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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99504472.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 89515563.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 85664734.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73607746.

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90

Wenwen Chen, Wei Wang, Xiaoxia Sun, Shanshan Xie, Xiaoyang Xu, Min Liu, Chunxia Yang, Min Li, Wen Zhang, Wei Liu, Liangjing Wang, Tianhua Zhou, Yuehong Yang

Cell Death Dis. 2020 Jul; 11(7): 534. Published online 2020 Jul 14. doi: 10.1038/s41419-020-02739-9

Correction in:: Cell Death Dis. 2024 Dec; 15(12): 886.

PMCID:: PMC7360774

Abstract Article PDF–3.3M

Select item 73220677.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 73083138.

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2

Chunqing Wang, Yongmei Li, Shuai Yan, Hao Wang, Xianfeng Shao, Mingming Xiao, Baicai Yang, Guoxuan Qin, Ruirui Kong, Ruibing Chen, Ning Zhang

Nat Commun. 2020; 11: 3162. Published online 2020 Jun 22. doi: 10.1038/s41467-020-16966-3

PMCID:: PMC7308313

Abstract Article PDF–2.9M

Select item 71127499.

IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection

Jeffery T. Kwock, Chelsea Handfield, Jutamas Suwanpradid, Peter Hoang, Michael J. McFadden, Kevin F. Labagnara, Lauren Floyd, Jessica Shannon, Ranjitha Uppala, Mrinal K. Sarkar, Johann E. Gudjonsson, David L. Corcoran, Helen M. Lazear, Gregory Sempowski, Stacy M. Horner, Amanda S. MacLeod

Sci Adv. 2020 Apr; 6(14): eaay3245. Published online 2020 Apr 1. doi: 10.1126/sciadv.aay3245

PMCID:: PMC7112749

Abstract Article PDF–621K

Select item 677813710.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 634248411.

Oligoadenylate synthetases family protein OASL inhibits DNA sensor cGAS activity during DNA virus infection to limit interferon production.

Arundhati Ghosh, Lulu Shao, Padmavathi Sampath, Baoyu Zhao, Nidhi V. Patel, Jianzhong Zhu, Bharat Behl, Robert A. Parise, Jan H. Beumer, Roderick J. O’Sullivan, Neal A. DeLuca, Stephen H. Thorne, Vijay A.K. Rathinam, Pingwei Li, Saumendra N. Sarkar

Immunity. Author manuscript; available in PMC 2020 Jan 15.

Published in final edited form as: Immunity. 2019 Jan 15; 50(1): 51–63.e5. Published online 2019 Jan 8. doi: 10.1016/j.immuni.2018.12.013

PMCID:: PMC6342484

Abstract Article PDF–2.1M

Select item 631010212.

Interactome and proteome dynamics uncover immune modulatory associations of the pathogen sensing factor cGAS

Krystal K. Lum, Bokai Song, Joel D. Federspiel, Benjamin A. Diner, Timothy Howard, Ileana M. Cristea

Cell Syst. Author manuscript; available in PMC 2019 Dec 26.

Published in final edited form as: Cell Syst. 2018 Dec 26; 7(6): 627–642.e6. Published online 2018 Nov 21. doi: 10.1016/j.cels.2018.10.010

PMCID:: PMC6310102

Abstract Article PDF–3.5M

Select item 583915813.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

Select item 562727514.

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

Zhen-Dong Xiao, Leng Han, Hyemin Lee, Li Zhuang, Yilei Zhang, Joelle Baddour, Deepak Nagrath, Christopher G. Wood, Jian Gu, Xifeng Wu, Han Liang, Boyi Gan

Nat Commun. 2017; 8: 783. Published online 2017 Oct 4. doi: 10.1038/s41467-017-00902-z

PMCID:: PMC5627275

Abstract Article PDF–1.1M

Select item 457792315.

2′-5′-Oligoadenylate Synthetase-Like Protein Inhibits Respiratory Syncytial Virus Replication and Is Targeted by the Viral Nonstructural Protein 1

Jayeeta Dhar, Rolando A. Cuevas, Ramansu Goswami, Jianzhong Zhu, Saumendra N. Sarkar, Sailen Barik

J Virol. 2015 Oct 1; 89(19): 10115–10119. Published online 2015 Jul 15. doi: 10.1128/JVI.01076-15

PMCID:: PMC4577923

Abstract Article PDF–872K

Select item 444644016.

Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling

Mikkel Søes Ibsen, Hans Henrik Gad, Line Lykke Andersen, Veit Hornung, Ilkka Julkunen, Saumendra N. Sarkar, Rune Hartmann

Nucleic Acids Res. 2015 May 26; 43(10): 5236–5248. Published online 2015 Apr 29. doi: 10.1093/nar/gkv389

PMCID:: PMC4446440

Abstract Article PDF–5.7M

Select item 410181217.

Antiviral activity of human oligoadenylate synthetases-like (OASL) is mediated by enhancing retinoic acid-inducible gene I (RIG-I) signaling

Jianzhong Zhu, Yugen Zhang, Arundhati Ghosh, Rolando A. Cuevas, Adriana Forero, Jayeeta Dhar, Mikkel Søes Ibsen, Jonathan Leo Schmid-Burgk, Tobias Schmidt, Madhavi K. Ganapathiraju, Takashi Fujita, Rune Hartmann, Sailen Barik, Veit Hornung, Carolyn B. Coyne, Saumendra N. Sarkar

Immunity. Author manuscript; available in PMC 2015 Jun 19.

Published in final edited form as: Immunity. 2014 Jun 19; 40(6): 936–948. Published online 2014 Jun 12. doi: 10.1016/j.immuni.2014.05.007

PMCID:: PMC4101812

Abstract Article PDF–4.1M

Select item 403683118.

HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells

Sami Kukkonen, Maria Del Pilar Martinez-Viedma, Nayoung Kim, Mariana Manrique, Anna Aldovini

Retrovirology. 2014; 11: 30. Published online 2014 Apr 17. doi: 10.1186/1742-4690-11-30

PMCID:: PMC4036831

Abstract Article PDF–1.8M

Select item 399919419.

New Variants Including ARG1 Polymorphisms Associated with C-Reactive Protein Levels Identified by Genome-Wide Association and Pathway Analysis

Nadimuthu Vinayagamoorthy, Hae-Jin Hu, Seon-Hee Yim, Seung-Hyun Jung, Jaeseong Jo, Sun Ha Jee, Yeun-Jun Chung

PLoS One. 2014; 9(4): e95866. Published online 2014 Apr 24. doi: 10.1371/journal.pone.0095866

PMCID:: PMC3999194

Abstract Article PDF–918K

Select item 351198420.

Genome-wide Association and Population Genetic Analysis of C-Reactive Protein in African American and Hispanic American Women

Alex P. Reiner, Sandra Beleza, Nora Franceschini, Paul L. Auer, Jennifer G. Robinson, Charles Kooperberg, Ulrike Peters, Hua Tang

Am J Hum Genet. 2012 Sep 7; 91(3): 502–512. doi: 10.1016/j.ajhg.2012.07.023

PMCID:: PMC3511984

Abstract Article PDF–742K

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