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Items: 1 to 20 of 30

1.
Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease
Dominic W. Kolonay, Kristina M. Sattler, Corinne Strawser, Jill Rafael-Fortney, Maria M. Mihaylova, Katherine E. Miller, Christoph Lepper, Kedryn K. Baskin
Front Cell Dev Biol. 2024; 12: 1331563. Published online 2024 Apr 16. doi: 10.3389/fcell.2024.1331563
PMCID:
PMC11058648
AbstractArticlePDF–3.8M
2.
The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation
Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang
Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548
PMCID:
PMC9386464
AbstractArticlePDF–6.6M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
The extent of cyclin C promoter occupancy directs changes in stress-dependent transcription
David C. Stieg, Katrina F. Cooper, Randy Strich
J Biol Chem. 2020 Nov 27; 295(48): 16280–16291. Published online 2020 Sep 15. doi: 10.1074/jbc.RA120.015215
PMCID:
PMC7705302
AbstractArticlePDF–2.1M
5.
Stress‐Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics
Jessica M. Ponce, Grace Coen, Kathryn M. Spitler, Nikola Dragisic, Ines Martins, Antentor Hinton, Jr, Margaret Mungai, Satya Murthy Tadinada, Hao Zhang, Gavin Y. Oudit, Long‐Sheng Song, Na Li, Peter Sicinski, Stefan Strack, E. Dale Abel, Colleen Mitchell, Duane D. Hall, Chad E. Grueter
J Am Heart Assoc. 2020 Apr 7; 9(7): e014366. Published online 2020 Apr 4. doi: 10.1161/JAHA.119.014366
PMCID:
PMC7428645
AbstractArticlePDF–1.9M
6.
Synergistic repression of thyroid hyperplasia by cyclin C and Pten
Jan Jezek, Kun Wang, Ruilan Yan, Antonio Di Cristofano, Katrina F. Cooper, Randy Strich
J Cell Sci. 2019 Aug 15; 132(16): jcs230029. Published online 2019 Aug 15. doi: 10.1242/jcs.230029
PMCID:
PMC6737908
AbstractArticle
7.
Mitochondrial translocation of cyclin C stimulates intrinsic apoptosis through Bax recruitment
Jan Jezek, Kai‐Ti Chang, Amogh M Joshi, Randy Strich
EMBO Rep. 2019 Sep; 20(9): e47425. Published online 2019 Aug 6. doi: 10.15252/embr.201847425
PMCID:
PMC6726902
AbstractArticlePDF–1.2M
8.
Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission
Vidyaramanan Ganesan, Stephen D. Willis, Kai-Ti Chang, Samuel Beluch, Katrina F. Cooper, Randy Strich
Mol Biol Cell. 2019 Feb 1; 30(3): 302–311. doi: 10.1091/mbc.E18-07-0463
PMCID:
PMC6589575
AbstractArticlePDF–1.1M
9.
Lin28-mediated temporal promotion of protein synthesis is crucial for neural progenitor cell maintenance and brain development in mice
Stephanie Herrlinger, Qiang Shao, Mei Yang, Qing Chang, Yang Liu, Xiaohan Pan, Hang Yin, Li-Wei Xie, Jian-Fu Chen
Development. 2019 May 15; 146(10): dev173765. Published online 2019 May 28. doi: 10.1242/dev.173765
PMCID:
PMC6550015
AbstractArticle
10.
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α
Ziyi Song, Alus M. Xiaoli, Quanwei Zhang, Yi Zhang, Ellen S. T. Yang, Sven Wang, Rui Chang, Zhengdong D. Zhang, Gongshe Yang, Randy Strich, Jeffrey E. Pessin, Fajun Yang
J Biol Chem. 2017 May 26; 292(21): 8918–8932. Published online 2017 Mar 28. doi: 10.1074/jbc.M117.776229
PMCID:
PMC5448125
AbstractArticlePDF–5.2M
11.
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis
Beatriz Aranda-Orgilles, Ricardo Saldaña-Meyer, Eric Wang, Eirini Trompouki, Anne Fassl, Stephanie Lau, Jasper Mullenders, Pedro P. Rocha, Ramya Raviram, María Guillamot, María Sánchez-Díaz, Kun Wang, Clarisse Kayembe, Nan Zhang, Leonela Amoasii, Avik Choudhuri, Jane A. Skok, Markus Schober, Danny Reinberg, Piotr Sicinski, Heinrich Schrewe, Aristotelis Tsirigos, Leonard I. Zon, Iannis Aifantis
Cell Stem Cell. Author manuscript; available in PMC 2017 Jan 26.
Published in final edited form as: Cell Stem Cell. 2016 Dec 1; 19(6): 784–799. Published online 2016 Aug 25. doi: 10.1016/j.stem.2016.08.004
PMCID:
PMC5268820
AbstractArticlePDF–1.7M
12.
mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC)
Daorong Feng, Dou Yeon Youn, Xiaoping Zhao, Yanguang Gao, William J. Quinn, 3rd, Alus M. Xiaoli, Yan Sun, Morris J. Birnbaum, Jeffrey E. Pessin, Fajun Yang
PLoS One. 2015; 10(6): e0126240. Published online 2015 Jun 4. doi: 10.1371/journal.pone.0126240
PMCID:
PMC4456374
AbstractArticlePDF–5.0M
13.
Cyclin C mediates stress-induced mitochondrial fission and apoptosis
Kun Wang, Ruilan Yan, Katrina F. Cooper, Randy Strich
Mol Biol Cell. 2015 Mar 15; 26(6): 1030–1043. doi: 10.1091/mbc.E14-08-1315
PMCID:
PMC4357504
AbstractArticlePDF–5.7M
14.
Cyclin C is a haploinsufficient tumor suppressor
Na Li, Anne Fassl, Joel Chick, Hiroyuki Inuzuka, Xiaoyu Li, Marc R. Mansour, Lijun Liu, Haizhen Wang, Bryan King, Shavali Shaik, Alejandro Gutierrez, Alban Ordureau, Tobias Otto, Taras Kreslavsky, Lukas Baitsch, Leah Bury, Clifford A. Meyer, Nan Ke, Kristin A. Mulry, Michael J. Kluk, Moni Roy, Sunkyu Kim, Xiaowu Zhang, Yan Geng, Agnieszka Zagozdzon, Sarah Jenkinson, Rosemary E. Gale, David C. Linch, Jean J. Zhao, Charles G. Mullighan, J. Wade Harper, Jon C. Aster, Iannis Aifantis, Harald von Boehmer, Steven P. Gygi, Wenyi Wei, A. Thomas Look, Piotr Sicinski
Nat Cell Biol. Author manuscript; available in PMC 2015 May 1.
Published in final edited form as: Nat Cell Biol. 2014 Nov; 16(11): 1080–1091. Published online 2014 Oct 26. doi: 10.1038/ncb3046
PMCID:
PMC4235773
AbstractArticlePDF–4.3M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module
Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David Elliott, Mark Solloway, Elisa Lenti, Chisa Hidaka, Ching-Pin Chang, Nizar Mahlaoui, Richard P. Harvey, Jean-Laurent Casanova, Licia Selleri
Dev Cell. Author manuscript; available in PMC 2013 May 15.
Published in final edited form as: Dev Cell. 2012 May 15; 22(5): 913–926. Published online 2012 May 3. doi: 10.1016/j.devcel.2012.02.009
PMCID:
PMC3356505
AbstractArticlePDF–6.8M
17.
PRC1 and PRC2 Are Not Required for Targeting of H2A.Z to Developmental Genes in Embryonic Stem Cells
Robert S. Illingworth, Catherine H. Botting, Graeme R. Grimes, Wendy A. Bickmore, Ragnhild Eskeland
PLoS One. 2012; 7(4): e34848. Published online 2012 Apr 9. doi: 10.1371/journal.pone.0034848
PMCID:
PMC3322156
AbstractArticlePDF–1.5M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
20.
An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells
Debbie L.C. van den Berg, Tim Snoek, Nick P. Mullin, Adam Yates, Karel Bezstarosti, Jeroen Demmers, Ian Chambers, Raymond A. Poot
Cell Stem Cell. 2010 Apr 2; 6(4): 369–381. doi: 10.1016/j.stem.2010.02.014
PMCID:
PMC2860243
AbstractArticle

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