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Items: 1 to 20 of 28

1.
Depletion of plasma thymidine results in growth retardation and mitochondrial myopathy in mice overexpressing human thymidine phosphorylase
Naomoto Harada, Haruka Nagasaki, Hiromi Yamamoto, Kenji Matsubara, Takamasa Suzuki, Akira Gomori, Tatsushi Yokogawa, Kenichi Matsuo, Kazutaka Miyadera
J Biol Chem. 2023 Mar; 299(3): 103002. Published online 2023 Feb 10. doi: 10.1016/j.jbc.2023.103002
PMCID:
PMC10020661
AbstractArticlePDF–3.3M
2.
Life-long persistence of nuclear RNAs in the mouse brain
Sara Zocher, Asako McCloskey, Anne Karasinsky, Roberta Schulte, Ulrike Friedrich, Mathias Lesche, Nicole Rund, Fred H. Gage, Martin W. Hetzer, Tomohisa Toda
Science. Author manuscript; available in PMC 2024 Apr 24.
Published in final edited form as: Science. 2024 Apr 5; 384(6691): 53–59. Published online 2024 Apr 4. doi: 10.1126/science.adf3481
PMCID:
PMC7615865
AbstractArticlePDF–2.3M
3.
Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate: Platelets stimulate endothelial cell migration
Giordano Pula, Elena Garonna, Warwick B Dunn, Michio Hirano, Giuseppe Pizzorno, Michelangelo Campanella, Edward L Schwartz, Mahmoud H el Kouni, Caroline PD Wheeler-Jones
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12): 2631–2638. Published online 2010 Sep 30. doi: 10.1161/ATVBAHA.110.215855
PMCID:
PMC7528120
AbstractArticlePDF–1.4M
4.
Single-cell analysis of cardiogenesis reveals basis for organ level developmental defects
T. Yvanka de Soysa, Sanjeev S. Ranade, Satoshi Okawa, Srikanth Ravichandran, Yu Huang, Hazel T. Salunga, Amelia Schricker, Antonio Del Sol, Casey A. Gifford, Deepak Srivastava
Nature. Author manuscript; available in PMC 2020 Jan 24.
Published in final edited form as: Nature. 2019 Aug; 572(7767): 120–124. Published online 2019 Jul 24. doi: 10.1038/s41586-019-1414-x
PMCID:
PMC6719697
AbstractArticlePDF–8.9M
5.
Administration of deoxyribonucleosides or inhibition of their catabolism as a pharmacological approach for mitochondrial DNA depletion syndrome
Yolanda Cámara, Emiliano González-Vioque, Mauro Scarpelli, Javier Torres-Torronteras, Andrea Caballero, Michio Hirano, Ramon Martí
Hum Mol Genet. 2014 May 1; 23(9): 2459–2467. Published online 2013 Dec 20. doi: 10.1093/hmg/ddt641
PMCID:
PMC6281351
AbstractArticlePDF–464K
6.
Uridine prevents tamoxifen-induced liver lipid droplet accumulation
Thuc T Le, Yasuyo Urasaki, Giuseppe Pizzorno
BMC Pharmacol Toxicol. 2014; 15: 27. Published online 2014 May 23. doi: 10.1186/2050-6511-15-27
PMCID:
PMC4064512
AbstractArticlePDF–3.0M
7.
Uridine Affects Liver Protein Glycosylation, Insulin Signaling, and Heme Biosynthesis
Yasuyo Urasaki, Giuseppe Pizzorno, Thuc T. Le
PLoS One. 2014; 9(6): e99728. Published online 2014 Jun 11. doi: 10.1371/journal.pone.0099728
PMCID:
PMC4053524
AbstractArticlePDF–1.6M
8.
Uridine Prevents Fenofibrate-Induced Fatty Liver
Thuc T. Le, Yasuyo Urasaki, Giuseppe Pizzorno
PLoS One. 2014; 9(1): e87179. Published online 2014 Jan 24. doi: 10.1371/journal.pone.0087179
PMCID:
PMC3901748
AbstractArticlePDF–2.8M
9.
Disruption of uridine homeostasis links liver pyrimidine metabolism to lipid accumulation
Thuc T. Le, Amy Ziemba, Yasuyo Urasaki, Eugene Hayes, Steven Brotman, Giuseppe Pizzorno
J Lipid Res. 2013 Apr; 54(4): 1044–1057. doi: 10.1194/jlr.M034249
PMCID:
PMC3605981
AbstractArticlePDF–2.0M
10.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
11.
Differential expression of uridine phosphorylase in tumors contributes to an improved fluoropyrimidine therapeutic activity
Deliang Cao, Amy Ziemba, James McCabe, Ruilan Yan, Laxiang Wan, Bradford Kim, Michael Gach, Stuart Flynn, Giuseppe Pizzorno
Mol Cancer Ther. Author manuscript; available in PMC 2012 Dec 1.
Published in final edited form as: Mol Cancer Ther. 2011 Dec; 10(12): 2330–2339. Published online 2011 Sep 27. doi: 10.1158/1535-7163.MCT-11-0202
PMCID:
PMC3397678
AbstractArticlePDF–904K
12.
A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity
Tarmo P. Roosild, Samantha Castronovo, Adelbert Villoso, Amy Ziemba, Giuseppe Pizzorno
J Struct Biol. Author manuscript; available in PMC 2012 Nov 1.
Published in final edited form as: J Struct Biol. 2011 Nov; 176(2): 229–237. Published online 2011 Aug 10. doi: 10.1016/j.jsb.2011.08.002
PMCID:
PMC3190963
AbstractArticlePDF–1.0M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres
Fuchou Tang, Catalin Barbacioru, Ellen Nordman, Siqin Bao, Caroline Lee, Xiaohui Wang, Brian B. Tuch, Edith Heard, Kaiqin Lao, M. Azim Surani
PLoS One. 2011; 6(6): e21208. Published online 2011 Jun 23. doi: 10.1371/journal.pone.0021208
PMCID:
PMC3121735
AbstractArticlePDF–1.0M
15.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
16.
Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice
Luis C. López, Hasan O. Akman, Ángeles García-Cazorla, Beatriz Dorado, Ramón Martí, Ichizo Nishino, Saba Tadesse, Giuseppe Pizzorno, Dikoma Shungu, Eduardo Bonilla, Kurenai Tanji, Michio Hirano
Hum Mol Genet. 2009 Feb 15; 18(4): 714–722. Published online 2008 Nov 21. doi: 10.1093/hmg/ddn401
PMCID:
PMC2638828
AbstractArticlePDF–290K
17.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
18.
Structural analyses reveal two distinct families of nucleoside phosphorylases.
Matthew J Pugmire, Steven E Ealick
Biochem J. 2002 Jan 1; 361(Pt 1): 1–25. doi: 10.1042/0264-6021:3610001
PMCID:
PMC1222293
SummaryPDF–1.8M
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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