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Items: 1 to 20 of 120

1.
Erythroid-intrinsic activation of TLR8 impairs erythropoiesis in inherited anemia
Jing Liang, Yang Wan, Jie Gao, Lingyue Zheng, Jingwei Wang, Peng Wu, Yue Li, Bingrui Wang, Ding Wang, Yige Ma, Biao Shen, Xue Lv, Di Wang, Na An, Xiaoli Ma, Guangfeng Geng, Jingyuan Tong, Jinhua Liu, Guo Chen, Meng Gao, Ryo Kurita, Yukio Nakamura, Ping Zhu, Hang Yin, Xiaofan Zhu, Lihong Shi
Nat Commun. 2024; 15: 5678. Published online 2024 Jul 6. doi: 10.1038/s41467-024-50066-w
PMCID:
PMC11227506
AbstractArticlePDF–3.5M
2.
TLR8 escapes X chromosome inactivation in human monocytes and CD4+ T cells
Ali Youness, Claire Cenac, Berenice Faz-López, Solange Grunenwald, Franck J. Barrat, Julie Chaumeil, José Enrique Mejía, Jean-Charles Guéry
Biol Sex Differ. 2023; 14: 60. Published online 2023 Sep 18. doi: 10.1186/s13293-023-00544-5
PMCID:
PMC10506212
AbstractArticlePDF–2.9M
3.
CD8 T Cell‐Derived Exosomal miR‐186‐5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis
Xiaodong Xu, Shuang Qu, Changming Zhang, Mingchao Zhang, Weisong Qin, Guisheng Ren, Hao Bao, Limin Li, Ke Zen, Zhihong Liu
Adv Sci (Weinh) 2023 Sep; 10(25): 2301492. Published online 2023 Jul 3. doi: 10.1002/advs.202301492
PMCID:
PMC10477851
AbstractArticlePDF–5.2M
4.
Human TLR8 induces inflammatory bone marrow erythromyeloblastic islands and anemia in SLE-prone mice
Naomi I Maria, Julien Papoin, Chirag Raparia, Zeguo Sun, Rachel Josselsohn, Ailing Lu, Hani Katerji, Mahrukh M Syeda, David Polsky, Robert Paulson, Theodosia Kalfa, Betsy J Barnes, Weijia Zhang, Lionel Blanc, Anne Davidson
Life Sci Alliance. 2023 Oct; 6(10): e202302241. Published online 2023 Jul 26. doi: 10.26508/lsa.202302241
PMCID:
PMC10372407
AbstractArticlePDF–3.7M
5.
Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8
Marie Dominique Ah Kioon, Claudio Tripodo, David Fernandez, Kyriakos A. Kirou, Robert F. Spiera, Mary K. Crow, Jessica K. Gordon, Franck J. Barrat
Sci Transl Med. Author manuscript; available in PMC 2023 Jan 21.
Published in final edited form as: Sci Transl Med. 2018 Jan 10; 10(423): eaam8458. doi: 10.1126/scitranslmed.aam8458
PMCID:
PMC9865429
AbstractArticlePDF–2.3M
6.
Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling
Chalystha Yie Qin Lee, Yee Teng Chan, Yi Ying Cheok, Grace Min Yi Tan, Ting Fang Tang, Heng Choon Cheong, Jamuna Vadivelu, Suhailah Abdullah, Chung Yeng Looi, Won Fen Wong
J Immunol Res. 2022; 2022: 3861518. Published online 2022 Oct 22. doi: 10.1155/2022/3861518
PMCID:
PMC9617731
AbstractArticlePDF–1.1M
7.
TLR-8, TNF-α, and ESR-1α Gene Polymorphism Susceptibility in Onset of Arthritis
Maryam Mukhtar, Nadeem Sheikh, Andleeb Batool, Tayyaba Saleem, Muhammad Babar Khawar, Mavra Irfan, Saira Kainat Suqaina
Genet Res (Camb) 2022; 2022: 9208765. Published online 2022 Sep 20. doi: 10.1155/2022/9208765
PMCID:
PMC9553836
AbstractArticlePDF–474K
8.
Gain-of-function defects in toll-like receptor 8 shed light on the interface between immune system and bone marrow failure disorders
Jack Bleesing
Front Immunol. 2022; 13: 935321. Published online 2022 Sep 2. doi: 10.3389/fimmu.2022.935321
PMCID:
PMC9479092
AbstractArticlePDF–1.5M
9.
CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes
Chao Yang, Mahesh Bachu, Yong Du, Caroline Brauner, Ruoxi Yuan, Marie Dominique Ah Kioon, Giancarlo Chesi, Franck J. Barrat, Lionel B. Ivashkiv
Nat Commun. 2022; 13: 3426. Published online 2022 Jun 14. doi: 10.1038/s41467-022-31132-7
PMCID:
PMC9195402
AbstractArticlePDF–3.4M
10.
RNA-Cholesterol Nanoparticles Function as Potent Immune Activators via TLR7 and TLR8
Hannah-Lena Obermann, Ines I. Lederbogen, Jenny Steele, Jens Dorna, Leif Erik Sander, Konrad Engelhardt, Udo Bakowsky, Andreas Kaufmann, Stefan Bauer
Front Immunol. 2021; 12: 658895. Published online 2022 Jan 21. doi: 10.3389/fimmu.2021.658895
PMCID:
PMC8814444
AbstractArticlePDF–5.2M
11.
Molecular docking of SARS-COV-2 Spike epitope sequences identifies heterodimeric peptide-protein complex formation with human Zo-1, TLR8 and brain specific glial proteins
Subhajit Dasgupta, Mausumi Bandyopadhyay
Med Hypotheses. 2021 Dec; 157: 110706. Published online 2021 Oct 13. doi: 10.1016/j.mehy.2021.110706
PMCID:
PMC8511551
AbstractArticlePDF–3.5M
12.
Monocyte-dependent co-stimulation of cytokine induction in human γδ T cells by TLR8 RNA ligands
Ruben Serrano, Christoph Coch, Christian Peters, Gunther Hartmann, Daniela Wesch, Dieter Kabelitz
Sci Rep. 2021; 11: 15231. Published online 2021 Jul 27. doi: 10.1038/s41598-021-94428-6
PMCID:
PMC8316369
AbstractArticlePDF–1.8M
13.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
14.
Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function
Jahnavi Aluri, Alicia Bach, Saara Kaviany, Luana Chiquetto Paracatu, Maleewan Kitcharoensakkul, Magdalena A. Walkiewicz, Christopher D. Putnam, Marwan Shinawi, Nermina Saucier, Elise M. Rizzi, Michael T. Harmon, Molly P. Keppel, Michelle Ritter, Morgan Similuk, Elaine Kulm, Michael Joyce, Adriana A. de Jesus, Raphaela Goldbach-Mansky, Yi-Shan Lee, Marina Cella, Peggy L. Kendall, Mary C. Dinauer, Jeffrey J. Bednarski, Christina Bemrich-Stolz, Scott W. Canna, Shirley M. Abraham, Matthew M. Demczko, Jonathan Powell, Stacie M. Jones, Amy M. Scurlock, Suk See De Ravin, Jack J. Bleesing, James A. Connelly, V. Koneti Rao, Laura G. Schuettpelz, Megan A. Cooper
Blood. 2021 May 6; 137(18): 2450–2462. Prepublished online 2020 Dec 23. doi: 10.1182/blood.2020009620
PMCID:
PMC8109013
AbstractArticle
15.
Successful Direct Acting Antiviral Therapy in Chronic Hepatitis C Normalizes IFNγ and IL2 Production in T Cells Together with TLR8 Expression and Functionality in Peripheral Blood Mononuclear Cells
María Teresa Arias-Loste, Joaquín Cabezas, Susana Llerena, Paula Iruzubieta, David San-Segundo, David Merino, Antonio Cuadrado, José Pedro Vaqué, Marcos López-Hoyos, Javier Crespo
Viruses. 2021 Apr; 13(4): 635. Published online 2021 Apr 7. doi: 10.3390/v13040635
PMCID:
PMC8068025
AbstractArticlePDF–10M
16.
SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway
Grant R. Campbell, Rachel K. To, Jonathan Hanna, Stephen A. Spector
iScience. 2021 Apr 23; 24(4): 102295. Published online 2021 Mar 9. doi: 10.1016/j.isci.2021.102295
PMCID:
PMC7939994
AbstractArticlePDF–3.7M
17.
STAT3 Silencing and TLR7/8 Pathway Activation Repolarize and Suppress Myeloid-Derived Suppressor Cells From Breast Cancer Patients
Elham Safarzadeh, Ali Mohammadi, Behzad Mansoori, Pascal H. G. Duijf, Shahryar Hashemzadeh, Vahid Khaze, Tohid Kazemi, Afshin Derakhshani, Nicola Silvestris, Behzad Baradaran
Front Immunol. 2020; 11: 613215. Published online 2021 Feb 19. doi: 10.3389/fimmu.2020.613215
PMCID:
PMC7933669
AbstractArticlePDF–4.3M
18.
Glucose metabolism characteristics and TLR8-mediated metabolic control of CD4+ Treg cells in ovarian cancer cells microenvironment
Rui Xu, Ming Wu, Shuna Liu, Wenwen Shang, Rong Li, Juan Xu, Lei Huang, Fang Wang
Cell Death Dis. 2021 Jan; 12(1): 22. Published online 2021 Jan 7. doi: 10.1038/s41419-020-03272-5
PMCID:
PMC7790820
AbstractArticlePDF–1.4M
19.
Association of Genetic Polymorphisms in TLR3, TLR4, TLR7, and TLR8 with the Clinical Forms of Dengue in Patients from Veracruz, Mexico
Araceli Posadas-Mondragón, José Leopoldo Aguilar-Faisal, Gerardo Zuñiga, Jonathan Javier Magaña, José Angel Santiago-Cruz, Edith Guillén-Salomón, Verónica Alcántara-Farfán, María Luisa Arellano-Flores, Juan Santiago Salas-Benito, Rocío M. Neri-Bazán, Lucero Luna-Rojas, Amanda Marineth Avila-Trejo, Adolfo Chávez-Negrete
Viruses. 2020 Nov; 12(11): 1230. Published online 2020 Oct 29. doi: 10.3390/v12111230
PMCID:
PMC7694044
AbstractArticlePDF–12M
20.
MAIT Cells Display a Specific Response to Type 1 IFN Underlying the Adjuvant Effect of TLR7/8 Ligands
Marion Pavlovic, Christelle Gross, Chahinaize Chili, Thomas Secher, Emmanuel Treiner
Front Immunol. 2020; 11: 2097. Published online 2020 Sep 8. doi: 10.3389/fimmu.2020.02097
PMCID:
PMC7509539
AbstractArticlePDF–2.7M

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