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Items: 1 to 20 of 96

1.
Chemogenetic Manipulation of Amygdala Kappa Opioid Receptor Neurons Modulates Amygdala Neuronal Activity and Neuropathic Pain Behaviors
Guangchen Ji, Peyton Presto, Takaki Kiritoshi, Yong Chen, Edita Navratilova, Frank Porreca, Volker Neugebauer
Cells. 2024 Apr; 13(8): 705. Published online 2024 Apr 19. doi: 10.3390/cells13080705
PMCID:
PMC11049235
AbstractArticlePDF–2.8M
2.
κ-Opioid receptor activation attenuates osteoarthritis synovitis by regulating macrophage polarization through the NF-κB pathway: KOR regulates OA synovitis via NF-κB
Yi Shi, Huaqiang Tao, Xueyan Li, Liyuan Zhang, Chunhui Li, Wen Sun, Miao Chu, Kai Chen, Pengfei Zhu, Qiang Wang, Chengyong Gu, Liangliang Wang, Xing Yang, Yuefeng Hao
Acta Biochim Biophys Sin (Shanghai) 2024 Jan 25; 56(1): 82–95. Published online 2023 Nov 28. doi: 10.3724/abbs.2023223
PMCID:
PMC10875361
AbstractArticlePDF–4.1M
3.
Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms
Arjun Muralidharan, Alexander Samoshkin, Marino Convertino, Marjo Hannele Piltonen, Pavel Gris, Jian Wang, Changyu Jiang, Richard Klares, III, Alexander Linton, Ru-Rong Ji, William Maixner, Nikolay V. Dokholyan, Jeffrey S. Mogil, Luda Diatchenko
Br J Pharmacol. Author manuscript; available in PMC 2023 Dec 5.
Published in final edited form as: Br J Pharmacol. 2021 Jul; 178(13): 2709–2726. Published online 2021 Apr 30. doi: 10.1111/bph.15463
PMCID:
PMC10697213
AbstractArticlePDF–2.1M
4.
The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology
Yu-Jun Wang, Gui-Ying Zan, Cenglin Xu, Xue-Ping Li, Xuelian Shu, Song-Yu Yao, Xiao-Shan Xu, Xiaoyun Qiu, Yexiang Chen, Kai Jin, Qi-Xin Zhou, Jia-Yu Ye, Yi Wang, Lin Xu, Zhong Chen, Jing-Gen Liu
Nat Commun. 2023; 14: 7903. Published online 2023 Nov 30. doi: 10.1038/s41467-023-43636-x
PMCID:
PMC10689794
AbstractArticlePDF–3.7M
5.
Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice
Jinyu Zhang, Ye Lu, Min Jia, Yuying Bai, Lulu Sun, Ziqing Dong, Wenrong Tian, Fangyuan Yin, Shuguang Wei, Yunpeng Wang
iScience. 2023 Sep 15; 26(9): 107536. Published online 2023 Aug 3. doi: 10.1016/j.isci.2023.107536
PMCID:
PMC10448166
AbstractArticlePDF–5.8M
6.
Kappa opioid receptor activation increases thermogenic energy expenditure which drives increased feeding
Aaron L. Cone, Kenny K. Wu, Alexxai V. Kravitz, Aaron J. Norris
iScience. 2023 Jul 21; 26(7): 107241. Published online 2023 Jun 28. doi: 10.1016/j.isci.2023.107241
PMCID:
PMC10362357
AbstractArticlePDF–4.5M
7.
A Cre Driver Line for Genetic Targeting of Kappa Opioid Receptor Expressing Cells
Franciely Paliarin, Chelsea Duplantis, Andrea F. Jones, Jessica Cucinello-Ragland, Samhita Basavanhalli, Emily Blaze, Evan Doré, Anna Isabella Neel, Haiguo Sun, Rong Chen, Scott Edwards, Nicholas W. Gilpin, Robert O. Messing, Rajani Maiya
eNeuro. 2023 Jul; 10(7): ENEURO.0043-23.2023. Prepublished online 2023 Jun 26. Published online 2023 Jul 11. doi: 10.1523/ENEURO.0043-23.2023
PMCID:
PMC10348446
AbstractArticlePDF–4.4M
8.
Conditional Deletion of KOR (Oprk1) in Kisspeptin Cells Does Not Alter LH Pulses, Puberty, or Fertility in Mice
Eulalia A Coutinho, Lourdes A Esparza, Alexandra D Hudson, Nathanael Rizo, Paige Steffen, Alexander S Kauffman
Endocrinology. 2022 Dec; 163(12): bqac175. Published online 2022 Oct 19. doi: 10.1210/endocr/bqac175
PMCID:
PMC10233252
AbstractArticle
9.
Kappa Opioid Receptors Reduce Serotonin Uptake and Escitalopram Efficacy in the Mouse Substantia Nigra Pars Reticulata
Alyssa M. West, Katherine M. Holleran, Sara R. Jones
Int J Mol Sci. 2023 Feb; 24(3): 2080. Published online 2023 Jan 20. doi: 10.3390/ijms24032080
PMCID:
PMC9916942
AbstractArticlePDF–2.0M
10.
Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal
Matthew B. Pomrenze, Daniel F. Cardozo Pinto, Peter A. Neumann, Pierre Llorach, Jason M. Tucciarone, Wade Morishita, Neir Eshel, Boris D. Heifets, Robert C. Malenka
Neuron. Author manuscript; available in PMC 2023 Dec 21.
Published in final edited form as: Neuron. 2022 Dec 21; 110(24): 4125–4143.e6. Published online 2022 Oct 5. doi: 10.1016/j.neuron.2022.09.024
PMCID:
PMC9789200
AbstractArticlePDF–3.5M
11.
The Basolateral Amygdala to Ventral Hippocampus Circuit Controls Anxiety-Like Behaviors Induced by Morphine Withdrawal
Cuola Deji, Peng Yan, Yuanyuan Ji, Xinyue Yan, Yue Feng, Jincen Liu, Yige Liu, Shuguang Wei, Yongsheng Zhu, Jianghua Lai
Front Cell Neurosci. 2022; 16: 894886. Published online 2022 Jun 2. doi: 10.3389/fncel.2022.894886
PMCID:
PMC9205755
AbstractArticlePDF–3.9M
12.
Agonist-promoted kappa opioid receptor (KOR) phosphorylation has behavioral endpoint-dependent and sex-specific effects
Peng Huang, Chongguang Chen, Danni Cao, Melody Huang, Lee-Yuan Liu-Chen
Neuropharmacology. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Neuropharmacology. 2022 Jan 1; 202: 108860. Published online 2021 Nov 2. doi: 10.1016/j.neuropharm.2021.108860
PMCID:
PMC9122667
AbstractArticlePDF–876K
13.
Experience-dependent myelination following stress is mediated by the neuropeptide dynorphin
Lindsay A. Osso, Kelsey A. Rankin, Jonah R. Chan
Neuron. Author manuscript; available in PMC 2022 Nov 17.
Published in final edited form as: Neuron. 2021 Nov 17; 109(22): 3619–3632.e5. Published online 2021 Sep 17. doi: 10.1016/j.neuron.2021.08.015
PMCID:
PMC8602781
AbstractArticlePDF–3.5M
14.
Kappa opioid receptor modulation of excitatory drive onto nucleus accumbens fast-spiking interneurons
Benjamin C. Coleman, Kevin M. Manz, Brad A. Grueter
Neuropsychopharmacology. 2021 Dec; 46(13): 2340–2349. Published online 2021 Aug 16. doi: 10.1038/s41386-021-01146-8
PMCID:
PMC8581025
AbstractArticlePDF–1.7M
15.
Kappa Opioid Receptor and Dynorphin Signaling in the Central Amygdala Regulates Alcohol Intake
Daniel W. Bloodgood, J. Andrew Hardaway, Christina M. Stanhope, Dipanwita Pati, Melanie M. Pina, Sofia Neira, Shivani Desai, Kristen M. Boyt, Richard D. Palmiter, Thomas L. Kash
Mol Psychiatry. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Mol Psychiatry. 2021 Jun; 26(6): 2187–2199. Published online 2020 Feb 25. doi: 10.1038/s41380-020-0690-z
PMCID:
PMC8124770
AbstractArticlePDF–1003K
16.
κ-Opioid Signaling in the Lateral Hypothalamic Area Modulates Nicotine-Induced Negative Energy Balance
Patricia Seoane-Collazo, Amparo Romero-Picó, Eva Rial-Pensado, Laura Liñares-Pose, Ánxela Estévez-Salguero, Johan Fernø, Rubén Nogueiras, Carlos Diéguez, Miguel López
Int J Mol Sci. 2021 Feb; 22(4): 1515. Published online 2021 Feb 3. doi: 10.3390/ijms22041515
PMCID:
PMC7913331
AbstractArticlePDF–2.1M
17.
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, András Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar
eLife. 2021; 10: e56519. Published online 2021 Feb 8. doi: 10.7554/eLife.56519
PMCID:
PMC7909954
AbstractArticlePDF–12M
18.
Characterization of a Knock-In Mouse Line Expressing a Fusion Protein of κ Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging via CLARITY
Chongguang Chen, Alex H. Willhouse, Peng Huang, Nora Ko, Yujun Wang, Bin Xu, Lan Hsuan Melody Huang, Brigitte Kieffer, Mary F. Barbe, Lee-Yuan Liu-Chen
eNeuro. 2020 Jul-Aug; 7(4): ENEURO.0028-20.2020. Prepublished online 2020 Jun 19. Published online 2020 Jul 17. doi: 10.1523/ENEURO.0028-20.2020
PMCID:
PMC7385665
AbstractArticlePDF–6.3M
19.
Kappa Opioid Receptors in the Bed Nucleus of the Stria Terminalis Regulate Binge-Like Alcohol Consumption in Male and Female Mice.
Harold L. Haun, William C. Griffin, Marcelo F. Lopez, Howard C. Becker
Neuropharmacology. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Neuropharmacology. 2020 May 1; 167: 107984. Published online 2020 Feb 2. doi: 10.1016/j.neuropharm.2020.107984
PMCID:
PMC7080606
AbstractArticlePDF–1.2M
20.
Synergy of distinct dopamine projection populations in behavioral reinforcement
Gabriel Heymann, Yong Sang Jo, Kathryn L. Reichard, Naomi McFarland, Charles Chavkin, Richard D. Palmiter, Marta E. Soden, Larry S. Zweifel
Neuron. Author manuscript; available in PMC 2021 Mar 4.
Published in final edited form as: Neuron. 2020 Mar 4; 105(5): 909–920.e5. Published online 2019 Dec 23. doi: 10.1016/j.neuron.2019.11.024
PMCID:
PMC7060117
AbstractArticlePDF–2.2M

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