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Items: 1 to 20 of 37

1.
Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration
Jin-Min Sun, Hong-Ye Fan, Yan Zhu, Ting-Ting Pan, Yong-Ping Wu, Dao-Yong Zhang, Xiao-Yu Hou
Life Sci Alliance. 2023 Dec; 6(12): e202301966. Published online 2023 Sep 21. doi: 10.26508/lsa.202301966
PMCID:
PMC10514360
AbstractArticlePDF–4.9M
2.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
3.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
4.
The Kinase MAP4K1 Inhibits Cytosolic RNA-Induced Antiviral Signaling by Promoting Proteasomal Degradation of TBK1/IKKε
Tian-Sheng He, Jingping Huang, Tian Chen, Zhi Zhang, Kuntai Cai, Jingge Yu, Liang-Guo Xu
Microbiol Spectr. 2021 Nov-Dec; 9(3): e01458-21. Published online 2021 Dec 15. doi: 10.1128/Spectrum.01458-21
PMCID:
PMC8672915
AbstractArticlePDF–4.7M
5.
MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
Qing Ling, Fenglin Li, Xiang Zhang, Shihui Mao, Xiangjie Lin, Jiajia Pan, Wenle Ye, Wenwen Wei, Yu Qian, Chao Hu, Xin Huang, Jinghan Wang, Huafeng Wang, Jiansong Huang, Yungui Wang, Jie Jin
EBioMedicine. 2021 Jul; 69: 103441. Published online 2021 Jun 21. doi: 10.1016/j.ebiom.2021.103441
PMCID:
PMC8239467
AbstractArticlePDF–5.1M
6.
Using yeast surface display to engineer a soluble and crystallizable construct of hematopoietic progenitor kinase 1 (HPK1)
Wai L. Lau, Bradley Pearce, Heather Malakian, Iyoncy Rodrigo, Dianlin Xie, Mian Gao, Frank Marsilio, Chiehying Chang, Max Ruzanov, Jodi K. Muckelbauer, John A. Newitt, Daša Lipovšek, Steven Sheriff
Acta Crystallogr F Struct Biol Commun. 2021 Jan 1; 77(Pt 1): 22–28. Published online 2020 Dec 22. doi: 10.1107/S2053230X20016015
PMCID:
PMC7805552
AbstractArticlePDF–865K
7.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
8.
MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
Gayoung Seo, Han Han, Rebecca Elizabeth Vargas, Bing Yang, Xu Li, Wenqi Wang
Cell Rep. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107860. doi: 10.1016/j.celrep.2020.107860
PMCID:
PMC7382313
AbstractArticlePDF–2.6M
9.
Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer
Xianzhou Song, Hironari Akasaka, Hua Wang, Reza Abbasgholizadeh, Ji-Hyun Shin, Fenglin Zang, Jiayi Chen, Craig D. Logsdon, Anirban Maitra, Andrew J. Bean, Huamin Wang
J Biol Chem. 2020 Feb 21; 295(8): 2348–2358. Published online 2020 Jan 20. doi: 10.1074/jbc.RA119.012186
PMCID:
PMC7039544
AbstractArticlePDF–2.9M
10.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
11.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
12.
A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals Molecular Determinants of Redox Homeostasis and NF-κB Signaling
Ramy H. Malty, Hiroyuki Aoki, Ashwani Kumar, Sadhna Phanse, Shahreen Amin, Qingzhou Zhang, Zoran Minic, Florian Goebels, Gabriel Musso, Zhuoran Wu, Hosam Abou-tok, Michael Meyer, Viktor Deineko, Sandy Kassir, Vishaldeep Sidhu, Matthew Jessulat, Nichollas E. Scott, Xuejian Xiong, James Vlasblom, Bhanu Prasad, Leonard J. Foster, Tiziana Alberio, Barbara Garavaglia, Haiyuan Yu, Gary D. Bader, Ken Nakamura, John Parkinson, Mohan Babu
Cell Syst. Author manuscript; available in PMC 2018 Dec 27.
Published in final edited form as: Cell Syst. 2017 Dec 27; 5(6): 564–577.e12. Published online 2017 Nov 8. doi: 10.1016/j.cels.2017.10.010
PMCID:
PMC5746455
AbstractArticlePDF–3.3M
13.
HPK1 positive expression associated with longer overall survival in patients with estrogen receptor-positive invasive ductal carcinoma-not otherwise specified
Jiaojiao Wang, Lijie Song, Sen Yang, Weijie Zhang, Pengwei Lu, Shenglei Li, Huixiang Li, Liuxing Wang
Mol Med Rep. 2017 Oct; 16(4): 4634–4642. Published online 2017 Aug 2. doi: 10.3892/mmr.2017.7131
PMCID:
PMC5647019
AbstractArticlePDF–1.4M
14.
Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer
Namgyu Lee, Dae-Kyum Kim, Seung Hyun Han, Hye Guk Ryu, Sung Jin Park, Kyong-Tai Kim, Kwan Yong Choi
Mol Cells. 2017 Sep 30; 40(9): 621–631. Published online 2017 Sep 20. doi: 10.14348/molcells.2017.0108
PMCID:
PMC5638770
AbstractArticlePDF–2.9M
15.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
16.
The Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization
Björn Titz, Tracey Low, Evangelia Komisopoulou, Sharon S Chen, Liudmilla Rubbi, Thomas G Graeber
Oncogene. Author manuscript; available in PMC 2017 Feb 14.
Published in final edited form as: Oncogene. 2010 Nov 4; 29(44): 5895–5910. Published online 2010 Aug 9. doi: 10.1038/onc.2010.331
PMCID:
PMC5308218
AbstractArticlePDF–3.8M
17.
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect
Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva
RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030
PMCID:
PMC4841607
AbstractArticlePDF–1.6M
18.
Proteasome-Mediated Degradation and Functions of Hematopoietic Progenitor Kinase 1 in Pancreatic Cancer
Hua Wang, Xianzhou Song, Craig Logsdon, Guisheng Zhou, Douglas B. Evans, James L. Abbruzzese, Stanley R. Hamilton, Tse-Hua Tan, Huamin Wang
Cancer Res. Author manuscript; available in PMC 2015 Apr 20.
Published in final edited form as: Cancer Res. 2009 Feb 1; 69(3): 1063–1070. Published online 2009 Jan 13. doi: 10.1158/0008-5472.CAN-08-1751
PMCID:
PMC4403239
AbstractArticlePDF–3.1M
19.
The CUL7/F-box and WD Repeat Domain Containing 8 (CUL7/Fbxw8) Ubiquitin Ligase Promotes Degradation of Hematopoietic Progenitor Kinase 1
Hua Wang, Yue Chen, Ping Lin, Lei Li, Guisheng Zhou, Guangchao Liu, Craig Logsdon, Jianping Jin, James L. Abbruzzese, Tse-Hua Tan, Huamin Wang
J Biol Chem. 2014 Feb 14; 289(7): 4009–4017. Published online 2013 Dec 20. doi: 10.1074/jbc.M113.520106
PMCID:
PMC3924268
AbstractArticlePDF–2.8M
20.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M

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