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Items: 1 to 20 of 1110

1.
AR Loss in Prostate Cancer Stroma Mediated by NF-κB and p38-MAPK Signaling Disrupts Stromal Morphogen Production
Tahsin Shekha, Neha S Sane, Cernyar Brent, Jiang Linan, Zohar Yitshak, Benjamin R Lee, Cindy K Miranti
Oncogene. Author manuscript; available in PMC 2025 Jan 6.
Published in final edited form as: Oncogene. 2024 Jun; 43(27): 2092–2103. Published online 2024 May 20. doi: 10.1038/s41388-024-03064-7
Correction in:
Oncogene. 2024 Nov 7
PMCID:
PMC11702291
AbstractArticlePDF–1.9M
2.
Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells
Kaisa-Mari Launonen, Vera Varis, Niina Aaltonen, Einari A Niskanen, Markku Varjosalo, Ville Paakinaho, Jorma J Palvimo
Nucleic Acids Res. 2024 Sep 9; 52(16): 9519–9535. Published online 2024 Aug 6. doi: 10.1093/nar/gkae653
PMCID:
PMC11381344
AbstractArticlePDF–3.2M
3.
Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells
Rachid Safi, Suzanne E. Wardell, Paige Watkinson, Xiaodi Qin, Marissa Lee, Sunghee Park, Taylor Krebs, Emma L. Dolan, Adam Blattler, Toshiya Tsuji, Surendra Nayak, Marwa Khater, Celia Fontanillo, Madeline A. Newlin, Megan L. Kirkland, Yingtian Xie, Henry Long, Emma C. Fink, Sean W. Fanning, Scott Runyon, Myles Brown, Shuichan Xu, Kouros Owzar, John D. Norris, Donald P. McDonnell
Nat Commun. 2024; 15: 7675. Published online 2024 Sep 3. doi: 10.1038/s41467-024-52032-y
PMCID:
PMC11371910
AbstractArticlePDF–3.6M
4.
Androgen receptor deficiency-induced TUG1 in suppressing ferroptosis to promote benign prostatic hyperplasia through the miR-188-3p/GPX4 signal pathway
Ming Zhan, Huan Xu, Guopeng Yu, Qi Chen, Ruifeng Yang, Yanbo Chen, Jianchao Ge, Zhong Wang, Ruimeng Yang, Bin Xu
Redox Biol. 2024 Sep; 75: 103298. Published online 2024 Aug 2. doi: 10.1016/j.redox.2024.103298
PMCID:
PMC11364272
AbstractArticlePDF–18M
5.
Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy
Maria Josè Polanco, Sara Parodi, Diana Piol, Conor Stack, Mathilde Chivet, Andrea Contestabile, Helen C. Miranda, Patricia M.-J. Lievens, Stefano Espinoza, Tobias Jochum, Anna Rocchi, Christopher Grunseich, Raul R. Gainetdinov, Andrew C. B. Cato, Andrew P. Lieberman, Albert R. La Spada, Fabio Sambataro, Kenneth H. Fischbeck, Illana Gozes, Maria Pennuto
Sci Transl Med. Author manuscript; available in PMC 2024 Aug 27.
Published in final edited form as: Sci Transl Med. 2016 Dec 21; 8(370): 370ra181. doi: 10.1126/scitranslmed.aaf9526
PMCID:
PMC11349029
AbstractArticlePDF–1.3M
6.
The miRNAs 203a/210‐3p/5001‐5p regulate the androgen/androgen receptor/YAP‐induced migration in prostate cancer cells
Chieh Huo, Ying‐Yu Kuo, Ching‐Yu Lin, Shine‐Gwo Shiah, Chia‐Yang Li, Shu‐Pin Huang, Jen‐Kun Chen, Wen‐Ching Wang, Hsing‐Jien Kung, Chih‐Pin Chuu
Cancer Med. 2024 Aug; 13(16): e70106. Published online 2024 Aug 16. doi: 10.1002/cam4.70106
PMCID:
PMC11327718
AbstractArticlePDF–15M
7.
The RNA secondary structure of androgen receptor-FL and V7 transcripts reveals novel regulatory regions
Warren B Rouse, Van S Tompkins, Collin A O’Leary, Walter N Moss
Nucleic Acids Res. 2024 Jun 24; 52(11): 6596–6613. Published online 2024 Mar 30. doi: 10.1093/nar/gkae220
PMCID:
PMC11194067
AbstractArticlePDF–1.8M
8.
Nuclear translocation of ADAM‐10 contributes to the pathogenesis and progression of human prostate cancer
Takashi Arima, Hideki Enokida, Hiroyuki Kubo, Ichiro Kagara, Ryouichirou Matsuda, Kazuki Toki, Hiroaki Nishimura, Takeshi Chiyomaru, Shuichi Tatarano, Toshihiko Idesako, Kenryu Nishiyama, Masayuki Nakagawa
Cancer Sci. 2007 Nov; 98(11): 1720–1726. Published online 2007 Aug 28. doi: 10.1111/j.1349-7006.2007.00601.x
PMCID:
PMC11158887
AbstractArticlePDF–1.0M
9.
Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs
Dong Han, Maryam Labaf, Yawei Zhao, Jude Owiredu, Songqi Zhang, Krishna Patel, Kavita Venkataramani, Jocelyn S. Steinfeld, Wanting Han, Muqing Li, Mingyu Liu, Zifeng Wang, Anna Besschetnova, Susan Patalano, Michaela J. Mulhearn, Jill A. Macoska, Xin Yuan, Steven P. Balk, Peter S. Nelson, Stephen R. Plymate, Shuai Gao, Kellee R. Siegfried, Ruihua Liu, Mary M. Stangis, Gabrielle Foxa, Piotr J. Czernik, Bart O. Williams, Kourosh Zarringhalam, Xiaohong Li, Changmeng Cai
J Clin Invest. 2024 Jun 3; 134(11): e168649. Published online 2024 Apr 30. doi: 10.1172/JCI168649
PMCID:
PMC11142739
AbstractArticlePDF–4.3M
10.
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability
Jonathan M. Tsai, Jacob D. Aguirre, Yen-Der Li, Jared Brown, Vivian Focht, Lukas Kater, Georg Kempf, Brittany Sandoval, Stefan Schmitt, Justine C. Rutter, Pius Galli, Colby R. Sandate, Jevon A. Cutler, Charles Zou, Katherine A. Donovan, Ryan J. Lumpkin, Simone Cavadini, Paul M.C. Park, Quinlan Sievers, Charlie Hatton, Elizabeth Ener, Brandon D. Regalado, Micah T. Sperling, Miko1aj S1abicki, Jeonghyeon Kim, Rebecca Zon, Zinan Zhang, Peter G. Miller, Roger Belizaire, Adam S. Sperling, Eric S. Fischer, Rafael Irizarry, Scott A. Armstrong, Nicolas H. Thomä, Benjamin L. Ebert
Mol Cell. Author manuscript; available in PMC 2024 May 29.
Published in final edited form as: Mol Cell. 2023 Aug 3; 83(15): 2753–2767.e10. Published online 2023 Jul 20. doi: 10.1016/j.molcel.2023.06.028
PMCID:
PMC11134608
AbstractArticlePDF–2.6M
11.
Interaction between Chromodomain Y-like Protein and Androgen Receptor Signaling in Sertoli Cells Accounts for Spermatogenesis
Kuo-Chung Lan, Yin-Hua Cheng, Yun-Chiao Chang, Kuo-Ting Wei, Pei-Ling Weng, Hong-Yo Kang
Cells. 2024 May; 13(10): 851. Published online 2024 May 16. doi: 10.3390/cells13100851
PMCID:
PMC11120535
AbstractArticlePDF–4.6M
12.
A 629RKLKK633 motif in the hinge region controls the androgen receptor at multiple levels
Tamzin M. Tanner, Sarah Denayer, Bart Geverts, Nora Van Tilborgh, Stefanie Kerkhofs, Christine Helsen, Lien Spans, Vanessa Dubois, Adriaan B. Houtsmuller, Frank Claessens, Annemie Haelens
Cell Mol Life Sci. 2010 Jun; 67(11): 1919–1927. Published online 2010 Feb 26. doi: 10.1007/s00018-010-0302-1
PMCID:
PMC11115488
AbstractArticlePDF–457K
13.
FBI-1 functions as a novel AR co-repressor in prostate cancer cells
Jiajun Cui, Yutao Yang, Chuanfu Zhang, Pinliang Hu, Wei Kan, Xianhong Bai, Xuelin Liu, Hongbin Song
Cell Mol Life Sci. 2011 Mar; 68(6): 1091–1103. Published online 2010 Sep 2. doi: 10.1007/s00018-010-0511-7
PMCID:
PMC11114496
AbstractArticlePDF–662K
14.
Pharmacological inhibition of androgen receptor expression induces cell death in prostate cancer cells
In-Sung Song, Yu Jeong Jeong, Jueun Kim, Kyoung-Hwa Seo, Nam-In Baek, Yunlim Kim, Choung-Soo Kim, Sung-Wuk Jang
Cell Mol Life Sci. 2020 Nov; 77(22): 4663–4673. Published online 2020 Jan 1. doi: 10.1007/s00018-019-03429-2
PMCID:
PMC11104930
AbstractArticlePDF–2.0M
15.
Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients
David W. James, Marcos Quintela, Lisa Lucini, Nour Al Abdullah Al Kafri, Gareth D. Healey, Nicholas Jones, Kinza Younas, Adnan Bunkheila, Lavinia Margarit, Lewis W. Francis, Deyarina Gonzalez, R. Steven Conlan
Front Endocrinol (Lausanne) 2024; 15: 1368494. Published online 2024 Apr 30. doi: 10.3389/fendo.2024.1368494
Correction in:
Front Endocrinol (Lausanne). 2024; 15: 1450375.
PMCID:
PMC11091321
AbstractArticlePDF–2.4M
16.
热激蛋白27联合miR-1介导雄激素受体上调导致雄激素性脱发发病
王 敏, 王 霞
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Jan 28; 47(1): 72–78. Chinese. doi: 10.11817/j.issn.1672-7347.2022.210131
PMCID:
PMC10930487
AbstractArticlePDF–890K
17.
Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression
Tianfang Ma, Lianjin Jin, Shanshan Bai, Zhan Liu, Shuo Wang, Beibei Shen, Yeyoung Cho, Subing Cao, Meijuan J S Sun, Ladan Fazli, David Zhang, Chiyaro Wedderburn, Derek Y Zhang, Gavisha Mugon, Nathan Ungerleider, Melody Baddoo, Kun Zhang, Lovisa Holmberg Schiavone, Brant R Burkhardt, Jia Fan, Zongbing You, Erik K Flemington, Xuesen Dong, Yan Dong
J Natl Cancer Inst. 2024 Mar; 116(3): 421–433. Published online 2023 Oct 17. doi: 10.1093/jnci/djad215
PMCID:
PMC10919334
AbstractArticlePDF–2.0M
18.
A plasma membrane–associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells
Hema Kalyanaraman, Darren E. Casteel, Shyamsundar Pal China, Shunhui Zhuang, Gerry R. Boss, Renate B. Pilz
Sci Signal. Author manuscript; available in PMC 2024 Mar 6.
Published in final edited form as: Sci Signal. 2024 Jan 30; 17(821): eadi7861. Published online 2024 Jan 30. doi: 10.1126/scisignal.adi7861
PMCID:
PMC10916501
AbstractArticlePDF–4.2M
19.
Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney
Lingyun Xiong, Jing Liu, Seung Yub Han, Kari Koppitch, Jin-Jin Guo, Megan Rommelfanger, Zhen Miao, Fan Gao, Ingileif B. Hallgrimsdottir, Lior Pachter, Junhyong Kim, Adam L. MacLean, Andrew P. McMahon
Dev Cell. Author manuscript; available in PMC 2024 Nov 6.
Published in final edited form as: Dev Cell. 2023 Nov 6; 58(21): 2338–2358.e5. Published online 2023 Sep 5. doi: 10.1016/j.devcel.2023.08.010
PMCID:
PMC10873092
AbstractArticlePDF–1.7M
20.
Identification of a Targetable JAK-STAT Enriched Androgen Receptor (AR) and AR Splice Variant Positive Triple Negative Breast Cancer Subtype
Sarah Asemota, Wendy Effah, Kirsten L. Young, Jeremiah Holt, Linnea Cripe, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Keely Mcnamara, Daniel Johnson, Yinan Wang, Brandy Grimes, Yekta Khosrosereshki, TJ Hollingsworth, Martin D. Fleming, Frances E. Pritchard, Ashley Hendrix, Farhan Khan, Meiyun Fan, Liza Makowski, Zheng Yin, Hironobu Sasano, D. Neil Hayes, Lawrence M. Pfeffer, Duane D. Miller, Ramesh Narayanan
Cell Rep. Author manuscript; available in PMC 2024 Feb 16.
Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113461. Published online 2023 Nov 17. doi: 10.1016/j.celrep.2023.113461
PMCID:
PMC10872270
AbstractArticlePDF–2.9M

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