PMC Links for GEO Profiles (Select 87136869) - PMC

Select item 87489581.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 67609012.

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

Jie Li, Guijun Shang, Yu-Ju Chen, Chad A Brautigam, Jen Liou, Xuewu Zhang, Xiao-chen Bai

eLife. 2019; 8: e47650. Published online 2019 Sep 19. doi: 10.7554/eLife.47650

PMCID:: PMC6760901

Abstract Article PDF–5.5M

Select item 66727763.

Glial Cell Line-Derived Neurotrophic Factor and Neurturin Inhibit Neurite Outgrowth and Activate RhoA through GFRα2b, an Alternatively Spliced Isoform of GFRα2

Li Foong Yoong, Heng-Phon Too

J Neurosci. 2007 May 23; 27(21): 5603–5614. doi: 10.1523/JNEUROSCI.4552-06.2007

PMCID:: PMC6672776

Abstract Article PDF–999K

Select item 66690144.

Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain

Janna M. Bigalke, Shintaro Aibara, Robert Roth, Göran Dahl, Euan Gordon, Sarah Dorbéus, A. Amunts, Jenny Sandmark

Sci Adv. 2019 Jul; 5(7): eaau4202. Published online 2019 Jul 31. doi: 10.1126/sciadv.aau4202

PMCID:: PMC6669014

Abstract Article PDF–6.0M

Select item 62371815.

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal dementia and GRN mutations: a genome-wide association study

Cyril Pottier, Xiaolai Zhou, Ralph B. Perkerson, III, Matt Baker, Gregory D. Jenkins, Daniel J. Serie, Roberta Ghidoni, Luisa Benussi, Giuliano Binetti, Prof Adolfo López de Munain, Miren Zulaica, Fermin Moreno, Isabelle Le Ber, Prof Florence Pasquier, Prof Didier Hannequin, Raquel Sánchez-Valle, Anna Antonell, Albert Lladó, Tammee M. Parsons, NiCole A. Finch, Elizabeth C. Finger, Prof Carol F. Lippa, Edward D. Huey, Prof Manuela Neumann, Prof Peter Heutink, Matthis Synofzik, Carlo Wilke, Robert A. Rissman, Prof Jaroslaw Slawek, Emilia Sitek, Peter Johannsen, Jørgen E. Nielsen, Yingxue Ren, Marka van Blitterswijk, Mariely DeJesus-Hernandez, Elizabeth Christopher, Melissa E. Murray, Kevin F. Bieniek, Bret M. Evers, Camilla Ferrari, Sara Rollinson, Anna Richardson, Prof Elio Scarpini, Giorgio G. Fumagalli, Prof Alessandro Padovani, Prof John Hardy, Parastoo Momeni, Raffaele Ferrari, Francesca Frangipane, Raffaele Maletta, Maria Anfossi, Maura Gallo, Prof Leonard Petrucelli, EunRan Suh, Prof Oscar L. Lopez, Tsz H. Wong, Jeroen G. J. van Rooij, Harro Seelaar, Prof Simon Mead, Prof Richard J. Caselli, Prof Eric M. Reiman, Prof Marwan Noel Sabbagh, Mads Kjolby, Prof Anders Nykjaer, Anna M. Karydas, Prof Adam L. Boxer, Lea T. Grinberg, Prof Jordan Grafman, Salvatore Spina, Adrian Oblak, Prof M-Marsel Mesulam, Prof Sandra Weintraub, Prof Changiz Geula, Prof John R. Hodges, Prof Olivier Piguet, William S. Brooks, David J. Irwin, Prof John Q. Trojanowski, Edward B. Lee, Prof Keith A. Josephs, Prof Joseph E. Parisi, Prof Nilüfer Ertekin-Taner, Prof David S. Knopman, Benedetta Nacmias, Irene Piaceri, Silvia Bagnoli, Prof Sandro Sorbi, Marla Gearing, Prof Jonathan Glass, Thomas G. Beach, Prof Sandra E. Black, Mario Masellis, Prof Ekaterina Rogaeva, Prof Jean-Paul Vonsattel, Prof Lawrence S. Honig, Julia Kofler, Prof Amalia C. Bruni, Prof Julie Snowden, Prof David Mann, Prof Stuart Pickering-Brown, Janine Diehl-Schmid, Prof Juliane Winkelmann, Daniela Galimberti, Prof Caroline Graff, Linn Öijerstedt, Claire Troakes, Prof Safa Al-Sarraj, Carlos Cruchaga, Prof Nigel J. Cairns, Jonathan D. Rohrer, Prof Glenda M. Halliday, John B. Kwok, Prof John C. van Swieten, Prof Charles L. White, III, Prof Bernardino Ghetti, Jill R. Murell, Prof Ian R. A. Mackenzie, Ging-Yuek R. Hsiung, Barbara Borroni, Giacomina Rossi, Fabrizio Tagliavini, Prof Zbigniew K. Wszolek, Prof Ronald C. Petersen, Prof Eileen H. Bigio, Prof Murray Grossman, Prof Vivianna M Van Deerlin, Prof William W. Seeley, Prof Bruce L. Miller, Prof Neill R. Graff-Radford, Prof Bradley F. Boeve, Prof Dennis W. Dickson, Prof Joanna M. Biernacka, Prof Rosa Rademakers

Lancet Neurol. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Lancet Neurol. 2018 Jun; 17(6): 548–558. Published online 2018 Apr 30. doi: 10.1016/S1474-4422(18)30126-1

PMCID:: PMC6237181

Abstract Article PDF–367K

Select item 59806566.

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease

SJ Furney, A Simmons, G Breen, I Pedroso, K Lunnon, P Proitsi, A Hodges, J Powell, L-O Wahlund, I Kloszewska, P Mecocci, H Soininen, M Tsolaki, B Vellas, C Spenger, M Lathrop, L Shen, S Kim, AJ Saykin, MW Weiner, S Lovestone

Mol Psychiatry. Author manuscript; available in PMC 2018 May 31.

Published in final edited form as: Mol Psychiatry. 2011 Nov; 16(11): 1130–1138. Published online 2010 Nov 30. doi: 10.1038/mp.2010.123

PMCID:: PMC5980656

Abstract Article PDF–439K

Select item 59007807.

Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling

Jenny Sandmark, Göran Dahl, Linda Öster, Bingze Xu, Patrik Johansson, Tomas Akerud, Anna Aagaard, Pia Davidsson, Janna M. Bigalke, Maria Sörhede Winzell, G. Jonah Rainey, Robert G. Roth

J Biol Chem. 2018 Apr 13; 293(15): 5492–5508. Published online 2018 Feb 2. doi: 10.1074/jbc.RA117.000820

PMCID:: PMC5900780

Abstract Article PDF–2.7M

Select item 49674778.

GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway

Hidekazu Ishida, Rie Saba, Ioannis Kokkinopoulos, Masakazu Hashimoto, Osamu Yamaguchi, Sonja Nowotschin, Manabu Shiraishi, Prashant Ruchaya, Duncan Miller, Stephen Harmer, Ariel Poliandri, Shigetoyo Kogaki, Yasushi Sakata, Leo Dunkel, Andrew Tinker, Anna-Katerina Hadjantonakis, Yoshiki Sawa, Hiroshi Sasaki, Keiichi Ozono, Ken Suzuki, Kenta Yashiro

Cell Rep. 2016 Jul 26; 16(4): 1026–1038. Published online 2016 Jul 7. doi: 10.1016/j.celrep.2016.06.050

Correction in:: Cell Rep. 2023 Nov 28; 42(11): 113383.

PMCID:: PMC4967477

Abstract Article

Select item 47372409.

A genome‐wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain

W. Meng, H.A. Deshmukh, N.R. van Zuydam, Y. Liu, L.A. Donnelly, K. Zhou, Wellcome Trust Case Control Consortium 2 (WTCCC2), Surrogate Markers for Micro‐ and Macro‐Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group, A.D. Morris, H.M. Colhoun, C.N.A. Palmer, B.H. Smith

Eur J Pain. 2015 Mar; 19(3): 392–399. Published online 2015 Mar 18. doi: 10.1002/ejp.560

PMCID:: PMC4737240

Abstract Article PDF–488K

Select item 409029710.

Expression of the pituitary stem/progenitor marker GFRα2 in human pituitary adenomas and normal pituitary

Nestoras Mathioudakis, Ram Sundaresh, Alexandra Larsen, William Ruff, Jennifer Schiller, Hugo Guerrero Cázares, Peter Burger, Roberto Salvatori, Alfredo Quiñones-Hinojosa

Pituitary. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Pituitary. 2015 Feb; 18(1): 31–41. doi: 10.1007/s11102-014-0553-1

PMCID:: PMC4090297

Abstract Article PDF–3.8M

Select item 404112311.

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Verneri Anttila, Bendik S. Winsvold, Padhraig Gormley, Tobias Kurth, Francesco Bettella, George McMahon, Mikko Kallela, Rainer Malik, Boukje de Vries, Gisela Terwindt, Sarah E. Medland, Unda Todt, Wendy L. McArdle, Lydia Quaye, Markku Koiranen, M. Arfan Ikram, Terho Lehtimäki, Anine H. Stam, Lannie Ligthart, Juho Wedenoja, Ian Dunham, Benjamin M. Neale, Priit Palta, Eija Hamalainen, Markus Schürks, Lynda M Rose, Julie E. Buring, Paul M. Ridker, Stacy Steinberg, Hreinn Stefansson, Finnbogi Jakobsson, Debbie A. Lawlor, David M. Evans, Susan M. Ring, Markus Färkkilä, Ville Artto, Mari A Kaunisto, Tobias Freilinger, Jean Schoenen, Rune R. Frants, Nadine Pelzer, Claudia M. Weller, Ronald Zielman, Andrew C. Heath, Pamela A.F. Madden, Grant W. Montgomery, Nicholas G. Martin, Guntram Borck, Hartmut Göbel, Axel Heinze, Katja Heinze-Kuhn, Frances M.K. Williams, Anna-Liisa Hartikainen, Anneli Pouta, Joyce van den Ende, Andre G. Uitterlinden, Albert Hofman, Najaf Amin, Jouke-Jan Hottenga, Jacqueline M. Vink, Kauko Heikkilä, Michael Alexander, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Heinz Erich Wichmann, Arpo Aromaa, Johan G. Eriksson, Bryan Traynor, Daniah Trabzuni, North American Brain Expression Consortium, UK Brain Expression Consortium, Elizabeth Rossin, Kasper Lage, Suzanne B.R. Jacobs, J. Raphael Gibbs, Ewan Birney, Jaakko Kaprio, Brenda W. Penninx, Dorret I. Boomsma, Cornelia van Duijn, Olli Raitakari, Marjo-Riitta Jarvelin, John-Anker Zwart, Lynn Cherkas, David P. Strachan, Christian Kubisch, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Martin Dichgans, Maija Wessman, George Davey Smith, Kari Stefansson, Mark J. Daly, Dale R. Nyholt, Daniel Chasman, Aarno Palotie

Nat Genet. Author manuscript; available in PMC 2014 Jun 2.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 912–917. Published online 2013 Jun 23. doi: 10.1038/ng.2676

PMCID:: PMC4041123

Article PDF–571K

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 173539313.

Investigation of germline GFRA4 mutations and evaluation of the involvement of GFRA1, GFRA2, GFRA3, and GFRA4 sequence variants in Hirschsprung disease

S Borrego, R Fernandez, H Dziema, A Niess, M Lopez-Alonso, G Antinolo, C Eng

J Med Genet. 2003 Mar; 40(3): e18. doi: 10.1136/jmg.40.3.e18

PMCID:: PMC1735393

Summary PDF–127K

Select item 52892814.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 13924115.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 2103316.

Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins

M. Sanicola, C. Hession, D. Worley, P. Carmillo, C. Ehrenfels, L. Walus, S. Robinson, G. Jaworski, H. Wei, R. Tizard, A. Whitty, R. B. Pepinsky, R. L. Cate

Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12): 6238–6243. doi: 10.1073/pnas.94.12.6238

PMCID:: PMC21033

Abstract Article PDF–391K

Select item 2046017.

GFRα3 is an orphan member of the GDNF/neurturin/persephin receptor family

Robert H. Baloh, Alexander Gorodinsky, Judith P. Golden, Malú G. Tansey, Catherine L. Keck, Nicholas C. Popescu, Eugene M. Johnson, Jr., Jeffrey Milbrandt

Proc Natl Acad Sci U S A. 1998 May 12; 95(10): 5801–5806. doi: 10.1073/pnas.95.10.5801

PMCID:: PMC20460

Abstract Article PDF–425K

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