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Select item 114766471.

Nrf2/Keap1/ARE regulation by plant secondary metabolites: a new horizon in brain tumor management

Saikat Dewanjee, Hiranmoy Bhattacharya, Chiranjib Bhattacharyya, Pratik Chakraborty, Joshua Fleishman, Athanasios Alexiou, Marios Papadakis, Saurabh Kumar Jha

Cell Commun Signal. 2024; 22: 497. Published online 2024 Oct 15. doi: 10.1186/s12964-024-01878-2

PMCID:: PMC11476647

Abstract Article PDF–3.3M

Select item 113691742.

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2024 Sep; 20(9): 1025–1048. Published online 2024 Jul 15. doi: 10.1038/s44320-024-00055-4

PMCID:: PMC11369174

Abstract Article PDF–2.7M

Select item 113028753.

NRF2-HIF2α Signaling Attenuates Endothelial Cell Senescence and Maintains Intercellular Junctions in Diabetes

Jian Shen, Yifan Lai, Yaner Lu, Yabin Liu, Jinlong Zhang, Yan Wu, Yunan Pan, Haibo Chen, Qiyue Gao, Qucheng Wei, Yuwen Chen, Jian Ye, Yinuo Lin, Bingchen Liu, Jun Jiang, Jinliang Nan

Int J Biol Sci. 2024; 20(10): 4055–4073. Published online 2024 Jul 22. doi: 10.7150/ijbs.96719

PMCID:: PMC11302875

Abstract Article PDF–11M

Select item 112620004.

Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer

Hong-Yuan Tsai, Mary P Bronner, Jordon K March, John F Valentine, Noah Freeman Shroyer, Lisa A Lai, Teresa A Brentnall, Sheng Pan, Ru Chen

Cancer Lett. Author manuscript; available in PMC 2024 Jul 22.

Published in final edited form as: Cancer Lett. 2022 Nov 28; 549: 215915. Published online 2022 Sep 13. doi: 10.1016/j.canlet.2022.215915

PMCID:: PMC11262000

Abstract Article PDF–3.7M

Select item 112397545.

Correlation of PD‐L1 expression with CD8+ T cells and oxidative stress‐related molecules NRF2 and NQO1 in esophageal squamous cell carcinoma

Xin Zhang, Yanan Yang, Hongying Zhao, Zhongqiu Tian, Qing Cao, Yunlong Li, Yajuan Gu, Qinfei Song, Xiumei Hu, Mulan Jin, Xingran Jiang

J Pathol Clin Res. 2024 Jul; 10(4): e12390. Published online 2024 Jul 11. doi: 10.1002/2056-4538.12390

PMCID:: PMC11239754

Abstract Article PDF–20M

Select item 111863656.

CPEB1 Controls NRF2 Proteostasis and Ferroptosis Susceptibility in Pancreatic Cancer

Shuxia Zhang, Jingnan Huang, Zhangzhang Lan, Yanlin Xiao, Youyou Liao, Shiva Basnet, Piying Huang, Yunze Li, Jingyu Yan, Yuling Sheng, Wenwen Zhou, Qi Liu, Haoyuan Tan, Yi Tan, Leyong Yuan, Lisheng Wang, Lingyun Dai, Wenyong Zhang, Changzheng Du

Int J Biol Sci. 2024; 20(8): 3156–3172. Published online 2024 Jun 3. doi: 10.7150/ijbs.95962

PMCID:: PMC11186365

Abstract Article PDF–19M

Select item 111480207.

PPIA dictates NRF2 stability to promote lung cancer progression

Weiqiang Lu, Jiayan Cui, Wanyan Wang, Qian Hu, Yun Xue, Xi Liu, Ting Gong, Yiping Lu, Hui Ma, Xinyu Yang, Bo Feng, Qi Wang, Naixia Zhang, Yechun Xu, Mingyao Liu, Ruth Nussinov, Feixiong Cheng, Hongbin Ji, Jin Huang

Nat Commun. 2024; 15: 4703. Published online 2024 Jun 3. doi: 10.1038/s41467-024-48364-4

PMCID:: PMC11148020

Abstract Article PDF–4.0M

Select item 111156278.

Céline René, Estelle Lopez, Mireille Claustres, Magali Taulan, Marie-Catherine Romey-Chatelain

Cell Mol Life Sci. 2010 Jul; 67(13): 2297–2309. Published online 2010 Mar 23. doi: 10.1007/s00018-010-0336-4

PMCID:: PMC11115627

Abstract Article PDF–608K

Select item 111134849.

Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy

Hadi Digaleh, Mahmoud Kiaei, Fariba Khodagholi

Cell Mol Life Sci. 2013 Dec; 70(24): 4681–4694. Published online 2013 Jun 26. doi: 10.1007/s00018-013-1409-y

PMCID:: PMC11113484

Abstract Article PDF–490K

Select item 1110831410.

Hepatitis B virus inhibits insulin receptor signaling and impairs liver regeneration via intracellular retention of the insulin receptor

Sebastian Robert Barthel, Regina Medvedev, Thekla Heinrich, Sarah Manon Büchner, Nadja Kettern, Eberhard Hildt

Cell Mol Life Sci. 2016 Nov; 73(21): 4121–4140. Published online 2016 May 7. doi: 10.1007/s00018-016-2259-1

PMCID:: PMC11108314

Abstract Article PDF–12M

Select item 1108889611.

Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern

Zhaoyuan Xue, Yiliyaer Nuerrula, Yilidana Sitiwaerdi, Mayinur Eli

Biomol Biomed. 2024 Jun 1; 24(3): 545–559. Published online 2024 Jun 1. doi: 10.17305/bb.2024.10184

PMCID:: PMC11088896

Abstract Article PDF–9.2M

Select item 1105939412.

Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2

Wei Dong, Qing Li, Xing Lu, Jianfeng Lan, Zhidong Qiu, Xuehong Wang, Junnan Wang, Xiaojiao Zheng, Sifan Chen, Chong Zhang, Junfei Jin

Exp Mol Med. 2024 Apr; 56(4): 946–958. Published online 2024 Apr 1. doi: 10.1038/s12276-024-01203-4

PMCID:: PMC11059394

Abstract Article PDF–7.4M

Select item 1102293413.

The Complicated Role of Nuclear Factor Erythroid-Derived 2-Like 2 in Allergy and Asthma

Cheryl E. Rockwell, Yining Jin, Allison P. Boss, Luca M. Kaiser, Saamera Awali

Drug Metab Dispos. 2022 Apr; 50(4): 500–507. Published online 2022 Apr. doi: 10.1124/dmd.121.000414

PMCID:: PMC11022934

Abstract Article PDF–209K

Select item 1100804614.

Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression

Rumeng Pan, Rongli Wang, Feiyan Cheng, Lihui Wang, Zhiwei Cui, Jing She, Xinyuan Yang

Reprod Biol Endocrinol. 2024; 22: 41. Published online 2024 Apr 11. doi: 10.1186/s12958-024-01208-8

PMCID:: PMC11008046

Abstract Article PDF–7.5M

Select item 1100237115.

Role of kidney function on Nrf2 mRNA levels in type 2 diabetes

Belinda Spoto, Cristina Politi, Maurizio Postorino, Rosa Maria Parlongo, Alessandra Testa, Giovanni Luigi Tripepi, Francesca Mallamaci, Carmine Zoccali

BMJ Open Diabetes Res Care. 2024; 12(2): e003929. Published online 2024 Apr 3. doi: 10.1136/bmjdrc-2023-003929

PMCID:: PMC11002371

Abstract Article PDF–304K

Select item 1099823216.

MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes

Lorenzo Franci, Giulia Vallini, Franca Maria Bertolino, Vittoria Cicaloni, Giovanni Inzalaco, Mattia Cicogni, Laura Tinti, Laura Calabrese, Virginia Barone, Laura Salvini, Pietro Rubegni, Federico Galvagni, Mario Chiariello

Redox Biol. 2024 Jun; 72: 103131. Published online 2024 Mar 28. doi: 10.1016/j.redox.2024.103131