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Select item 111504041.

Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration

M. Gabriele Bixel, Kishor K. Sivaraj, Melanie Timmen, Vishal Mohanakrishnan, Anusha Aravamudhan, Susanne Adams, Bong-Ihn Koh, Hyun-Woo Jeong, Kai Kruse, Richard Stange, Ralf H. Adams

Nat Commun. 2024; 15: 4575. Published online 2024 Jun 4. doi: 10.1038/s41467-024-48579-5

PMCID:: PMC11150404

Abstract Article PDF–9.1M

Select item 111441942.

IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development

Roshana Thambyrajah, Maria Maqueda, Muhammad Zaki Fadlullah, Martin Proffitt, Wen Hao Neo, Yolanda Guillén, Marta Casado-Pelaez, Patricia Herrero-Molinero, Carla Brujas, Noemi Castelluccio, Jessica González, Arnau Iglesias, Laura Marruecos, Cristina Ruiz-Herguido, Manel Esteller, Elisabetta Mereu, Georges Lacaud, Lluis Espinosa, Anna Bigas

Nat Commun. 2024; 15: 4673. Published online 2024 Jun 1. doi: 10.1038/s41467-024-48854-5

PMCID:: PMC11144194

Abstract Article PDF–3.9M

Select item 108820553.

Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate

Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluis Espinosa, Anna Bigas

Nat Commun. 2024; 15: 1604. Published online 2024 Feb 21. doi: 10.1038/s41467-024-45716-y

PMCID:: PMC10882055

Abstract Article PDF–6.6M

Select item 108766484.

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek

Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8

PMCID:: PMC10876648

Abstract Article PDF–10M

Select item 108615785.

Palmitic acid in type 2 diabetes mellitus promotes atherosclerotic plaque vulnerability via macrophage Dll4 signaling

Xiqiang Wang, Ling Zhu, Jing Liu, Yanpeng Ma, Chuan Qiu, Chengfeng Liu, Yangchao Gong, Ya Yuwen, Gongchang Guan, Yong Zhang, Shuo Pan, Junkui Wang, Zhongwei Liu

Nat Commun. 2024; 15: 1281. Published online 2024 Feb 12. doi: 10.1038/s41467-024-45582-8

PMCID:: PMC10861578

Abstract Article PDF–4.5M

Select item 108465396.

eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling

Lorraine Eley, Rachel V. Richardson, Ahlam Alqahtani, Bill Chaudhry, Deborah J. Henderson

Dis Model Mech. 2024 Jan 1; 17(1): dmm050265. Published online 2024 Jan 22. doi: 10.1242/dmm.050265

PMCID:: PMC10846539

Abstract Article

Select item 102674757.

PRDM16 regulates arterial development and vascular integrity

Michael Thompson, Masahide Sakabe, Mark Verba, Jiukuan Hao, Stryder M. Meadows, Q. Richard Lu, Mei Xin

Front Physiol. 2023; 14: 1165379. Published online 2023 Jun 1. doi: 10.3389/fphys.2023.1165379

PMCID:: PMC10267475

Abstract Article PDF–4.4M

Select item 101889078.

Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy

Jia-Lu Liu, Lei Zhang, Ying Huang, Xiao-Hui Li, Yi-Fei Liu, Shu-Min Zhang, Yue-E Zhao, Xiao-Jun Chen, Yu Liu, Li-Yu He, Zheng Dong, Fu-You Liu, Lin Sun, Li Xiao

Mol Ther. 2023 May 3; 31(5): 1451–1467. Published online 2023 Apr 3. doi: 10.1016/j.ymthe.2023.03.027

PMCID:: PMC10188907

Abstract Article PDF–8.5M

Select item 101192339.

Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties

Timothy Sargis, Seock-Won Youn, Krishna Thakkar, L. A. Naiche, Na Yoon Paik, Kostandin V. Pajcini, Jan K. Kitajewski

Angiogenesis. 2023; 26(2): 249–263. Published online 2022 Nov 15. doi: 10.1007/s10456-022-09861-6

PMCID:: PMC10119233

Abstract Article PDF–5.8M

Select item 1006544910.

PI(4,5)P₂-dependent regulation of endothelial tip cell specification contributes to angiogenesis

Elizabeth M. Davies, Rajendra Gurung, Kai Qin Le, Katherine T. T. Roan, Richard P. Harvey, Geraldine M. Mitchell, Quenten Schwarz, Christina A. Mitchell

Sci Adv. 2023 Mar; 9(13): eadd6911. Published online 2023 Mar 31. doi: 10.1126/sciadv.add6911

PMCID:: PMC10065449

Abstract Article PDF–3.5M

Select item 972074311.

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility

Mariam Rusidzé, Mélanie C. Faure, Pierre Sicard, Isabelle Raymond-Letron, Frank Giton, Emilie Vessieres, Vincent Prevot, Daniel Henrion, Jean-François Arnal, Charlotte A. Cornil, Françoise Lenfant

Development. 2022 Oct 1; 149(19): dev200683. Published online 2022 Oct 13. doi: 10.1242/dev.200683

PMCID:: PMC9720743

Abstract Article

Select item 957513512.

Delta‐like ligand‐4 regulates Notch‐mediated maturation of second heart field progenitor‐derived pharyngeal arterial endothelial cells

Prashan De Zoysa, Omar Toubat, Drayton C. Harvey, Christopher Yi, Jiang Liu, Susana Cavallero, Young‐Kwon Hong, Henry M. Sucov, Subramanyan Ram Kumar

J Cell Mol Med. 2022 Oct; 26(20): 5181–5194. Published online 2022 Sep 9. doi: 10.1111/jcmm.17542

PMCID:: PMC9575135

Abstract Article PDF–19M

Select item 936001613.

Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1

Daisuke Nagakubo, Mayumi Hirakawa, Norimasa Iwanami, Thomas Boehm

Sci Rep. 2022; 12: 13554. Published online 2022 Aug 8. doi: 10.1038/s41598-022-17844-2

PMCID:: PMC9360016

Abstract Article PDF–4.8M

Select item 929951114.

Dll4 Inhibition Promotes Graft Retention in Fat Grafting Enriched with Adipose-Derived Stem Cells

Choong-kun Lee, Bo-Yoon Park, Taehee Jo, Cheol-Heum Park, Ju-Hee Kim, Kyu-Jin Chung, Yong-Ha Kim, Do Young Park, Il-Kug Kim

Stem Cells Transl Med. 2022 Jul; 11(7): 742–752. Published online 2022 May 17. doi: 10.1093/stcltm/szac034

PMCID:: PMC9299511

Abstract Article PDF–79M

Select item 911033315.

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs

Yan Ting Shue, Alexandros P. Drainas, Nancy Yanzhe Li, Sarah M. Pearsall, Derrick Morgan, Nasa Sinnott-Armstrong, Susan Q. Hipkins, Garry L. Coles, Jing Shan Lim, Anthony E. Oro, Kathryn L. Simpson, Caroline Dive, Julien Sage

Nat Commun. 2022; 13: 2690. Published online 2022 May 16. doi: 10.1038/s41467-022-30416-2

PMCID:: PMC9110333

Abstract Article PDF–7.0M

Select item 905487916.

Unique functions for Notch4 in murine embryonic lymphangiogenesis

Ajit Muley, Minji Kim Uh, Glicella Salazar-De Simone, Bhairavi Swaminathan, Jennifer M. James, Aino Murtomaki, Seock Won Youn, Joseph D. McCarron, Chris Kitajewski, Maria Gnarra Buethe, Gloria Riitano, Yoh-suke Mukouyama, Jan Kitajewski, Carrie J. Shawber

Angiogenesis. 2022; 25(2): 205–224. Published online 2021 Oct 19. doi: 10.1007/s10456-021-09822-5

PMCID:: PMC9054879

Abstract Article PDF–6.8M

Select item 899508717.

FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac

Nanbing Li-Villarreal, Rebecca Lee Yean Wong, Monica D. Garcia, Ryan S. Udan, Ross A. Poché, Tara L. Rasmussen, Alexander M. Rhyner, Joshua D. Wythe, Mary E. Dickinson

Development. 2022 Apr 1; 149(7): dev200131. Published online 2022 Apr 1. doi: 10.1242/dev.200131

PMCID:: PMC8995087

Abstract Article

Select item 898800818.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 897588919.

Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals

Siyuan Hou, Zongcheng Li, Ji Dong, Yun Gao, Zhilin Chang, Xiaochen Ding, Shuaili Li, Yunqiao Li, Yang Zeng, Qian Xin, Baihan Wang, Yanli Ni, Xiaowei Ning, Yuqiong Hu, Xiaoying Fan, Yu Hou, Xianlong Li, Lu Wen, Bin Zhou, Bing Liu, Fuchou Tang, Yu Lan

Cell Res. 2022 Apr; 32(4): 333–348. Published online 2022 Jan 25. doi: 10.1038/s41422-022-00615-z

PMCID:: PMC8975889

Abstract Article PDF–7.1M

Select item 880935920.

Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects

Jacinta I. Kalisch-Smith, Emily C. Morris, Mary A. A. Strevens, Andia N. Redpath, Kostantinos Klaourakis, Dorota Szumska, Jennifer E. Outhwaite, Xin Sun, Joaquim Miguel Vieira, Nicola Smart, Sarah De Val, Paul R. Riley, Duncan B. Sparrow

Front Genet. 2021; 12: 806136. Published online 2022 Jan 19. doi: 10.3389/fgene.2021.806136