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Select item 112608121.

Toward the development of a sporadic model of Alzheimer's disease: comparing pathologies between humanized APP and the familial J20 mouse models

Peggy Rentsch, Kiruthika Ganesan, Alexander Langdon, Lyndsey M. Konen, Bryce Vissel

Front Aging Neurosci. 2024; 16: 1421900. Published online 2024 Jul 8. doi: 10.3389/fnagi.2024.1421900

PMCID:: PMC11260812

Abstract Article PDF–2.7M

Select item 108280032.

Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer’s disease by capillary western blotting

Luke T. Milham, Gary P. Morris, Lyndsey M. Konen, Peggy Rentsch, Nesli Avgan, Bryce Vissel

Front Mol Neurosci. 2023; 16: 1338065. Published online 2024 Jan 17. doi: 10.3389/fnmol.2023.1338065

PMCID:: PMC10828003

Abstract Article PDF–4.6M

Select item 106559983.

Two mouse models of Alzheimer’s disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein

Silvia A. Purro, Michael Farmer, Elizabeth Noble, Claire J. Sarell, Megan Powell, Daniel Yip, Lauren Giggins, Leila Zakka, David X. Thomas, Mark Farrow, Andrew J. Nicoll, Dominic Walsh, John Collinge

PLoS One. 2023; 18(11): e0294465. Published online 2023 Nov 17. doi: 10.1371/journal.pone.0294465

PMCID:: PMC10655998

Abstract Article PDF–2.2M

Select item 105782154.

Activation of TNF Receptor 2 Improves Synaptic Plasticity and Enhances Amyloid-β Clearance in an Alzheimer’s Disease Mouse Model with Humanized TNF Receptor 2

Natalia Ortí-Casañ, Harald Wajant, H. Bea Kuiperij, Annelien Hooijsma, Leon Tromp, Isabelle L. Poortman, Norick Tadema, Julia H.E. de Lange, Marcel M. Verbeek, Peter P. De Deyn, Petrus J.W. Naudé, Ulrich L.M. Eisel

J Alzheimers Dis. 2023; 94(3): 977–991. Prepublished online 2023 Jun 19. Published online 2023 Aug 1. doi: 10.3233/JAD-221230

PMCID:: PMC10578215

Abstract Article PDF–782K

Select item 105768135.

KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors

Bo Zhang, Chen Zhao, Wenchen Shen, Wei Li, Yue Zheng, Xiangfei Kong, Junbao Wang, Xudong Wu, Tao Zeng, Ying Liu, Yan Zhou

Nat Commun. 2023; 14: 6489. Published online 2023 Oct 14. doi: 10.1038/s41467-023-42322-2

PMCID:: PMC10576813

Abstract Article PDF–13M

Select item 105481736.

Microglia‐synapse engulfment via PtdSer‐TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models

Javier Rueda‐Carrasco, Dimitra Sokolova, Sang‐Eun Lee, Thomas Childs, Natália Jurčáková, Gerard Crowley, Sebastiaan De Schepper, Judy Z Ge, Joanne I Lachica, Christina E Toomey, Oliver J Freeman, John Hardy, Samuel J Barnes, Tammaryn Lashley, Beth Stevens, Sunghoe Chang, Soyon Hong

EMBO J. 2023 Oct; 42(19): e113246. Published online 2023 Aug 14. doi: 10.15252/embj.2022113246

Correction in:: EMBO J. 2024 Sep; 43(17): 3807–3811.

PMCID:: PMC10548173

Abstract Article PDF–3.3M

Select item 105372077.

The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer’s disease

Amanda L. Wright, Lyndsey M. Konen, Bruce G. Mockett, Gary P. Morris, Anurag Singh, Lisseth Estefania Burbano, Luke Milham, Monica Hoang, Raphael Zinn, Rose Chesworth, Richard P. Tan, Gordon A. Royle, Ian Clark, Steven Petrou, Wickliffe C. Abraham, Bryce Vissel

Mol Neurodegener. 2023; 18: 65. Published online 2023 Sep 28. doi: 10.1186/s13024-023-00632-5

PMCID:: PMC10537207

Abstract Article PDF–6.3M

Select item 104523198.

The Expression of Epac2 and GluA3 in an Alzheimer’s Disease Experimental Model and Postmortem Patient Samples

Tong Zhang, Nshunge Musheshe, Christina H. J. T. M. van der Veen, Helmut W. Kessels, Amalia Dolga, Peter De Deyn, Ulrich Eisel, Martina Schmidt

Biomedicines. 2023 Aug; 11(8): 2096. Published online 2023 Jul 25. doi: 10.3390/biomedicines11082096

PMCID:: PMC10452319

Abstract Article PDF–2.4M

Select item 102682409.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 1025366710.

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer

Luis Puelles, Matias Hidalgo-Sánchez

Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769

PMCID:: PMC10253667

Abstract Article PDF–6.8M

Select item 1000344911.

Alzheimer’s Amyloid β Peptide Induces Angiogenesis in an Alzheimer’s Disease Model Mouse through Placental Growth Factor and Angiopoietin 2 Expressions

Abdullah Md. Sheikh, Shozo Yano, Shatera Tabassum, Shingo Mitaki, Makoto Michikawa, Atsushi Nagai

Int J Mol Sci. 2023 Mar; 24(5): 4510. Published online 2023 Feb 24. doi: 10.3390/ijms24054510

PMCID:: PMC10003449

Abstract Article PDF–2.5M

Select item 993929312.

Excitation-inhibition imbalance disrupts visual familiarity in amyloid and non-pathology conditions

Suraj Niraula, Julia J. Doderer, Shreya Indulkar, Kalen P. Berry, William L. Hauser, Oliver J. L’Esperance, Jasmine Z. Deng, Griffin Keeter, Adam G. Rouse, Jaichandar Subramanian

Cell Rep. Author manuscript; available in PMC 2023 Feb 20.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111946. Published online 2023 Jan 4. doi: 10.1016/j.celrep.2022.111946

PMCID:: PMC9939293

Abstract Article PDF–2.7M

Select item 982066313.

iTRAQ-Based Proteomic Analysis of APP Transgenic Mouse Urine Exosomes

Xiaojing Zhou, Abdullah Md. Sheikh, Ken-ichi Matsumoto, Shingo Mitaki, Abu Zaffar Shibly, Yuchi Zhang, Garu A, Shozo Yano, Atsushi Nagai

Int J Mol Sci. 2023 Jan; 24(1): 672. Published online 2022 Dec 30. doi: 10.3390/ijms24010672

PMCID:: PMC9820663

Abstract Article PDF–5.6M

Select item 970995814.

Zbtb20 identifies and controls a thymus derived population of regulatory T cells that play a role in intestinal homeostasis

Agata K. Krzyzanowska, Rashade A.H. Haynes, II, Damian Kovalovsky, Hsinching Lin, Louis Osorio, Karen L. Edelblum, Lynn M. Corcoran, Arnold B. Rabson, Lisa K. Denzin, Derek B. Sant’Angelo

Sci Immunol. Author manuscript; available in PMC 2022 Nov 30.

Published in final edited form as: Sci Immunol. 2022 May 6; 7(71): eabf3717. Published online 2022 May 6. doi: 10.1126/sciimmunol.abf3717

PMCID:: PMC9709958

Abstract Article PDF–2.8M

Select item 957397915.

BAF (mSWI/SNF) complex regulates mediolateral cortical patterning in the developing forebrain

Huong Nguyen, Godwin Sokpor, Arpan Parichha, Linh Pham, Nidhi Saikhedkar, Yuanbin Xie, Pauline Antonie Ulmke, Joachim Rosenbusch, Mehdi Pirouz, Rüdiger Behr, Anastassia Stoykova, Beate Brand-Saberi, Huu Phuc Nguyen, Jochen F. Staiger, Shubha Tole, Tran Tuoc

Front Cell Dev Biol. 2022; 10: 1011109. Published online 2022 Oct 3. doi: 10.3389/fcell.2022.1011109

PMCID:: PMC9573979

Abstract Article PDF–5.6M

Select item 955397916.

Caspase-1 inhibition improves cognition without significantly altering amyloid and inflammation in aged Alzheimer disease mice

Joseph Flores, Marie-Lyne Fillion, Andréa C. LeBlanc

Cell Death Dis. 2022 Oct; 13(10): 864. Published online 2022 Oct 11. doi: 10.1038/s41419-022-05290-x

PMCID:: PMC9553979

Abstract Article PDF–4.4M

Select item 948242817.

A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model

Natalia Ortí-Casañ, Inge S. Zuhorn, Petrus J. W. Naudé, Peter P. De Deyn, Pauline E. M. van Schaik, Harald Wajant, Ulrich L. M. Eisel

Proc Natl Acad Sci U S A. 2022 Sep 13; 119(37): e2201137119. Published online 2022 Aug 29. doi: 10.1073/pnas.2201137119

PMCID:: PMC9482428

Abstract Article PDF–1.7M

Select item 923350418.

14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer’s Disease Mouse Models

Mary Gannon, Bing Wang, Sara Anne Stringfellow, Stephan Quintin, Itzel Mendoza, Thanushri Srikantha, A. Claire Roberts, Takashi Saito, Takaomi C. Saido, Erik D. Roberson, Talene A. Yacoubian

eNeuro. 2022 May-Jun; 9(3): ENEURO.0368-21.2022. Prepublished online 2022 Jun 13. Published online 2022 Jun 22. doi: 10.1523/ENEURO.0368-21.2022

PMCID:: PMC9233504

Abstract Article PDF–4.6M

Select item 917707319.

Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models

E. Sandra Chocron, Erin Munkácsy, Harper S. Kim, Przemyslaw Karpowicz, Nisi Jiang, Candice E. Van Skike, Nicholas DeRosa, Andy Q. Banh, Juan P. Palavicini, Paweł Wityk, Leszek Kalinowski, Veronica Galvan, Pawel A. Osmulski, Elzbieta Jankowska, Maria Gaczynska, Andrew M. Pickering

Sci Adv. 2022 Jun; 8(23): eabk2252. Published online 2022 Jun 8. doi: 10.1126/sciadv.abk2252

PMCID:: PMC9177073

Abstract Article PDF–6.1M

Select item 913128920.

MIR205HG is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary

Qiumei Du, Ashley R. Hoover, Igor Dozmorov, Prithvi Raj, Shaheen Khan, Erika Molina, Tsung-Cheng Chang, M. Teresa de la Morena, Ondine B. Cleaver, Joshua T. Mendell, Nicolai S.C. van Oers

Dev Cell. Author manuscript; available in PMC 2022 May 25.

Published in final edited form as: Dev Cell. 2019 May 20; 49(4): 618–631.e5. Published online 2019 Apr 11. doi: 10.1016/j.devcel.2019.03.012