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Select item 111156631.

Granzyme B is recovered by natural killer cells via clathrin-dependent endocytosis

Pan Li, Guoying Zheng, Yan Yang, Chunguang Zhang, Ping Xiong, Yong Xu, Min Fang, Zheng Tan, Fang Zheng, Feili Gong

Cell Mol Life Sci. 2010 Sep; 67(18): 3197–3208. Published online 2010 May 7. doi: 10.1007/s00018-010-0377-8

PMCID:: PMC11115663

Abstract Article PDF–783K

Select item 110309922.

Foxp3⁺ cell infiltration and granzyme B⁺/Foxp3⁺ cell ratio are associated with outcome in neoadjuvant chemotherapy-treated ovarian carcinoma

Martin Pölcher, Michael Braun, Nicolaus Friedrichs, Christian Rudlowski, Eva Bercht, Rolf Fimmers, Axel Sauerwald, Mignon-Denise Keyver-Paik, Kirsten Kübler, Reinhard Büttner, Walther C. Kuhn, Juan-José Hernando

Cancer Immunol Immunother. 2010 Jun; 59(6): 909–919. Published online 2010 Jan 20. doi: 10.1007/s00262-010-0817-1

PMCID:: PMC11030992

Abstract Article PDF–919K

Select item 107109673.

Does the expression of granzyme B participate in inflammation, fibrosis, and fertility of hydatid cysts?

Dina Sweed, Mohamed Mohamady, Marwa A. Gouda, Yahya Fayed, Sara A. Saied, Sara M. Abd Elhamed

Parasitol Res. 2024; 123(1): 22. Published online 2023 Dec 11. doi: 10.1007/s00436-023-08056-2

PMCID:: PMC10710967

Abstract Article PDF–2.7M

Select item 105076774.

Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children

Sandra McCullough, Harsh Dweep, Mitchell R. McGill, Sudeepa Bhattacharyya, Laura James, Sara Frankowski, Aaron Woodall, Gregory Kearns, Pritmohinder Gill

Microrna. Author manuscript; available in PMC 2023 Sep 19.

Published in final edited form as: Microrna. 2020; 9(2): 121–132. doi: 10.2174/2211536608666190808144456

PMCID:: PMC10507677

Abstract Article PDF–1.7M

Select item 104997015.

The mRNA expression and secretion of granzyme B are up-regulated via the histamine H2 receptor in human CD4⁺ T cells

Damilola Dawodu, Sophie Sand, Eirini Nikolouli, Thomas Werfel, Susanne Mommert

Inflamm Res. 2023; 72(8): 1525–1538. Published online 2023 Jul 20. doi: 10.1007/s00011-023-01759-3

PMCID:: PMC10499701

Abstract Article PDF–3.3M

Select item 102278626.

Clonally-Expanded, Thyrotoxic Effector CD8⁺ T cells Driven by IL-21 Contribute to Checkpoint Inhibitor Thyroiditis

Melissa G. Lechner, Zikang Zhou, Aline T. Hoang, Nicole Huang, Jessica Ortega, Lauren N. Scott, Ho-Chung Chen, Anushi Y. Patel, Rana Yakhshi-Tafti, Kristy Kim, Willy Hugo, Pouyan Famini, Alexandra Drakaki, Antoni Ribas, Trevor E. Angell, Maureen A. Su

Sci Transl Med. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Sci Transl Med. 2023 May 17; 15(696): eadg0675. Published online 2023 May 17. doi: 10.1126/scitranslmed.adg0675

PMCID:: PMC10227862

Abstract Article PDF–2.1M

Select item 101670727.

Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro

Lebogang Ramatsui, Tendamudzimu Harmfree Dongola, Tawanda Zininga, Gabriele Multhoff, Addmore Shonhai

Cell Stress Chaperones. 2023 May; 28(3): 321–331. Published online 2023 Apr 19. doi: 10.1007/s12192-023-01339-8

PMCID:: PMC10167072

Abstract Article PDF–1.4M

Select item 99529678.

Granzyme B in Autoimmune Skin Disease

Anna Gleave, David J. Granville

Biomolecules. 2023 Feb; 13(2): 388. Published online 2023 Feb 18. doi: 10.3390/biom13020388

PMCID:: PMC9952967

Abstract Article PDF–1.4M

Select item 96821799.

Granzyme B in circulating CD8+ T cells as a biomarker of immunotherapy effectiveness and disability in neuromyelitis optica spectrum disorders

Ziyan Shi, Qin Du, Xiaofei Wang, Jianchen Wang, Hongxi Chen, Yanling Lang, Lingyao Kong, Wenqin Luo, Mu Yang, Hongyu Zhou

Front Immunol. 2022; 13: 1027158. Published online 2022 Nov 9. doi: 10.3389/fimmu.2022.1027158

PMCID:: PMC9682179

Abstract Article PDF–2.4M

Select item 950024510.

Decreased GZMB, NRP1, ITPR1, and SERPINB9 Transcripts Lead to Reduced Regulatory T Cells Suppressive Capacity in Generalized Vitiligo Patients

Prashant S. Giri, Ankit H. Bharti, Mitesh Dwivedi

J Immunol Res. 2022; 2022: 3426717. Published online 2022 Sep 15. doi: 10.1155/2022/3426717

PMCID:: PMC9500245

Abstract Article PDF–1.8M

Select item 923928211.

Expression of the GZMB Gene Polymorphism, SNP rs8192917, in 990 Han Chinese Patients with Postoperative Keloids

Xiulin Wen, Huicong Du, Xiaoyan Hao, Jingrong Wang, Yuan Guo

Med Sci Monit. 2022; 28: e936963-1–e936963-10. Prepublished online 2022 Jun 1. Published online 2022 Jun 23. doi: 10.12659/MSM.936963

PMCID:: PMC9239282

Abstract Article PDF–1.0M

Select item 903574812.

Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes

Hélène Jamann, Qiao-Ling Cui, Haritha L. Desu, Florian Pernin, Olivier Tastet, Alexandre Halaweh, Negar Farzam-kia, Victoria Hannah Mamane, Oumarou Ouédraogo, Aurélie Cleret-Buhot, Audrey Daigneault, Renaud Balthazard, Wendy Klement, Florent Lemaître, Nathalie Arbour, Jack Antel, Jo Anne Stratton, Catherine Larochelle

Front Immunol. 2022; 13: 850616. Published online 2022 Apr 11. doi: 10.3389/fimmu.2022.850616

PMCID:: PMC9035748

Abstract Article PDF–9.4M

Select item 871966113.

Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B

Anneleen Daemen, Akshata R. Udyavar, Thomas Sandmann, Congfen Li, Linda J. W. Bosch, William O’Gorman, Yijin Li, Amelia Au-Yeung, Chikara Takahashi, Omar Kabbarah, Richard Bourgon, Priti Hegde, Carlos Bais, Meghna Das Thakur

PLoS One. 2021; 16(12): e0262198. Published online 2021 Dec 31. doi: 10.1371/journal.pone.0262198

PMCID:: PMC8719661

Abstract Article PDF–2.6M

Select item 866491014.

Gut bacteria induce granzyme B expression in human colonic ILC3s in vitro in an IL-15-dependent manner

Moriah J. Castleman, Stephanie M. Dillon, Tezha A. Thompson, Mario L. Santiago, Martin D. McCarter, Edward Barker, Cara C. Wilson

J Immunol. Author manuscript; available in PMC 2022 Jun 15.

Published in final edited form as: J Immunol. 2021 Jun 15; 206(12): 3043–3052. Published online 2021 Jun 11. doi: 10.4049/jimmunol.2000239

PMCID:: PMC8664910

Abstract Article PDF–1.7M

Select item 864136615.

Elevated Extracellular Levels of Granzymes in Patients with Scrub Typhus

Joo-Hee Hwang, Jeong-Hwan Hwang, Chang-Seop Lee

Am J Trop Med Hyg. 2021 Dec; 105(6): 1680–1683. Published online 2021 Oct 11. doi: 10.4269/ajtmh.20-1369

PMCID:: PMC8641366

Abstract Article PDF–666K

Select item 850711616.

Correlation of peripheral CD4+GranzB+CTLs with disease severity in patients with primary Sjögren’s syndrome

Qi Wang, Nan Che, Chengyin Lu, Xiaoxuan Sun, Yanyan Wang, Qiang Wang, Wenfeng Tan, Lanlan Zhou, Xiaojun Zhang, Dong Xu, Lei Gu, Miaojia Zhang

Arthritis Res Ther. 2021; 23: 257. Published online 2021 Oct 12. doi: 10.1186/s13075-021-02632-6

PMCID:: PMC8507116

Abstract Article PDF–2.8M

Select item 809431317.

Role of Cytotoxic Protease Granzyme‐b in Neuronal Degeneration During Human Stroke

Ganta Vijay Chaitanya, Prabhakar Eeka, Reinhold Munker, Jonathan Steven Alexander, Phanithi Prakash Babu

Brain Pathol. 2011 Jan; 21(1): 16–30. Published online 2010 Dec 3. doi: 10.1111/j.1750-3639.2010.00426.x

PMCID:: PMC8094313

Abstract Article PDF–2.3M

Select item 805316218.

Granzyme B in peripheral blood mononuclear cells as a measure of cell-mediated immune response in paraneoplastic neurological syndromes and malignancy

Mikołaj Piotr Zaborowski, Patrycja Stefens-Stawna, Krystyna Osztynowicz, Tomasz Piorunek, Halina Batura-Gabryel, Agnieszka Dyzmann-Sroka, Wojciech Kozubski, Ewa Nowak-Markwitz, Sławomir Michalak

Cancer Immunol Immunother. 2021 May; 70(5): 1277–1289. Published online 2020 Nov 2. doi: 10.1007/s00262-020-02750-1

PMCID:: PMC8053162

Abstract Article PDF–1.4M

Select item 797832719.

Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma

Yuxiang Ma, Xi Chen, Ao Wang, Hongyun Zhao, Qingguang Lin, Hua Bao, Yang Zhang, Shaodong Hong, Wanxiangfu Tang, Yan Huang, Yunpeng Yang, Xue Wu, Yang Shao, Wenfeng Fang, Li Zhang

J Immunother Cancer. 2021; 9(3): e002014. Published online 2021 Mar 18. doi: 10.1136/jitc-2020-002014

PMCID:: PMC7978327

Abstract Article PDF–908K

Select item 793597320.

Cytotoxic CD8⁺ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling

Icia Santos-Zas, Jeremie Lemarié, Ivana Zlatanova, Marine Cachanado, Jean-Christophe Seghezzi, Hakim Benamer, Pascal Goube, Marie Vandestienne, Raphael Cohen, Maya Ezzo, Vincent Duval, Yujiao Zhang, Jin-Bo Su, Alain Bizé, Lucien Sambin, Philippe Bonnin, Maxime Branchereau, Christophe Heymes, Corinne Tanchot, José Vilar, Clement Delacroix, Jean-Sebastien Hulot, Clement Cochain, Patrick Bruneval, Nicolas Danchin, Alain Tedgui, Ziad Mallat, Tabassome Simon, Bijan Ghaleh, Jean-Sébastien Silvestre, Hafid Ait-Oufella

Nat Commun. 2021; 12: 1483. Published online 2021 Mar 5. doi: 10.1038/s41467-021-21737-9

PMCID:: PMC7935973

Abstract Article PDF–5.4M

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