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Select item 97080861.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 92152272.

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication

Hainan Liu, Yu Bai, Xun Zhang, Ting Gao, Yue Liu, Entao Li, Xuefeng Wang, Zheng Cao, Lin Zhu, Qincai Dong, Yong Hu, Guangfei Wang, Caiwei Song, Xiayang Niu, Tong Zheng, Di Wang, Zijing Liu, Yanwen Jin, Ping Li, Xiuwu Bian, Cheng Cao, Xuan Liu

J Virol. 2022 Jun; 96(12): e00412-22. Published online 2022 Jun 2. doi: 10.1128/jvi.00412-22

PMCID:: PMC9215227

Abstract Article PDF–4.2M

Select item 85252373.

KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2

Siyuan Xu, Siqing Wang, Shenghui Xing, Dingdang Yu, Bowen Rong, Hai Gao, Mengyao Sheng, Yun Tan, Yifan Zhang, Xiaojian Sun, Kankan Wang, Kai Xue, Zhennan Shi, Fei Lan

Blood Adv. 2021 Sep 14; 5(17): 3241–3253. Published online 2021 Aug 27. doi: 10.1182/bloodadvances.2020002819

Correction in:: Blood Adv. 2022 Apr 12; 6(7): 2443.

PMCID:: PMC8525237

Abstract Article PDF–2.1M

Select item 83641814.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 82203915.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 81015326.

NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia

Xibao Yu, Ardalan Mansouri, Zhuandi Liu, Rili Gao, Kehan Li, Cunte Chen, Youxue Huang, Zheng Chen, Shaohua Chen, Yuhong Lu, Yangqiu Li, Chengwu Zeng, Yixin Zeng

Clin Transl Med. 2021 May; 11(5): e418. Published online 2021 May 6. doi: 10.1002/ctm2.418

PMCID:: PMC8101532

Article PDF–4.2M

Select item 73220677.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699838.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67426469.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 671971810.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik

Nat Genet. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1

PMCID:: PMC6719718

Abstract Article PDF–1.3M

Select item 664913411.

Quantitative detection of PML‐RARα fusion transcript by real‐time PCR with a single primer pair

Mariko Takenokuchi, Yuji Nakamachi, Keiko Yoneda, Kana Joo, Seiji Kawano, Eiji Tatsumi, Katsuyasu Saigo, Shunichi Kumagai

J Clin Lab Anal. 2009; 23(4): 223–230. Published online 2009 Jul 21. doi: 10.1002/jcla.20306

PMCID:: PMC6649134

Abstract Article PDF–198K

Select item 648477212.

S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia

Maurizio Gianni, Mineko Terao, Mami Kurosaki, Gabriela Paroni, Laura Brunelli, Roberta Pastorelli, Adriana Zanetti, Monica Lupi, Andrea Acquavita, Marco Bolis, Maddalena Fratelli, Cecile Rochette-Egly, Enrico Garattini

Oncogene. 2019; 38(14): 2482–2500. Published online 2018 Dec 7. doi: 10.1038/s41388-018-0599-z

Correction in:: Oncogene. 2023; 42(3): 254–258.

PMCID:: PMC6484772

Abstract Article PDF–7.7M

Select item 616668213.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 551489114.

RARα2 and PML-RAR similarities in the control of basal and retinoic acid induced myeloid maturation of acute myeloid leukemia cells

Maurizio Gianni, Maddalena Fratelli, Marco Bolis, Mami Kurosaki, Adriana Zanetti, Gabriela Paroni, Alessandro Rambaldi, Gianmaria Borleri, Cecile Rochette-Egly, Mineko Terao, Enrico Garattini

Oncotarget. 2017 Jun 6; 8(23): 37041–37060. Published online 2016 Jul 13. doi: 10.18632/oncotarget.10556

PMCID:: PMC5514891

Abstract Article PDF–7.0M

Select item 535790715.

Regulation of NF-κB by PML and PML-RARα

Abrar Ahmed, Xiaochun Wan, Izaskun Mitxitorena, Andrew J. Lindsay, Pier Paolo Pandolfi, Mary W. McCaffrey, Karen Keeshan, Youhai H. Chen, Ruaidhrí J. Carmody

Sci Rep. 2017; 7: 44539. Published online 2017 Mar 20. doi: 10.1038/srep44539

PMCID:: PMC5357907

Abstract Article PDF–1.3M

Select item 468531216.

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis

Giorgio Oliviero, Nayla Munawar, Ariane Watson, Gundula Streubel, Gwendolyn Manning, Vivian Bardwell, Adrian P. Bracken, Gerard Cagney

Sci Rep. 2015; 5: 18388. Published online 2015 Dec 21. doi: 10.1038/srep18388

PMCID:: PMC4685312

Abstract Article PDF–1.5M

Select item 453701317.

Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia

Francesco Albano, Antonella Zagaria, Luisa Anelli, Nicoletta Coccaro, Giuseppina Tota, Claudia Brunetti, Crescenzio Francesco Minervini, Luciana Impera, Angela Minervini, Angelo Cellamare, Paola Orsini, Cosimo Cumbo, Paola Casieri, Giorgina Specchia

Oncotarget. 2015 May 30; 6(15): 13269–13277. Published online 2015 Apr 18. doi: 10.18632/oncotarget.3773

PMCID:: PMC4537013

Abstract Article PDF–2.9M

Select item 437689318.

Development and Validation of a 3-Plex RT-qPCR Assay for the Simultaneous Detection and Quantitation of the Three PML-RARa Fusion Transcripts in Acute Promyelocytic Leukemia

Zhanguo Chen, Yongqing Tong, Yan Li, Qingping Gao, Qiongyu Wang, Chaohong Fu, Zunen Xia

PLoS One. 2015; 10(3): e0122530. Published online 2015 Mar 27. doi: 10.1371/journal.pone.0122530

PMCID:: PMC4376893

Abstract Article PDF–1.2M

Select item 426658819.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 419835820.

MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia

Cheng-Wu Zeng, Zhen-Hua Chen, Xing-Ju Zhang, Bo-Wei Han, Kang-Yu Lin, Xiao-Juan Li, Pan-Pan Wei, Hua Zhang, Yangqiu Li, Yue-Qin Chen

Autophagy. 2014 Oct 1; 10(10): 1726–1737. Published online 2014 Jul 18. doi: 10.4161/auto.29592

PMCID:: PMC4198358

Abstract Article PDF–5.0M

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