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Items: 1 to 20 of 22

1.
Extra centrosomes delay DNA damage–driven tumorigenesis
Vincent Z. Braun, Gerlinde Karbon, Fabian Schuler, Marina A. Schapfl, Johannes G. Weiss, Paul Y. Petermann, Diana C.J. Spierings, Andrea E. Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Sci Adv. 2024 Mar 29; 10(13): eadk0564. Published online 2024 Mar 29. doi: 10.1126/sciadv.adk0564
PMCID:
PMC10980279
AbstractArticlePDF–5.0M
2.
PIDDosome-SCAP crosstalk controls high fructose diet dependent transition from simple steatosis to steatohepatitis
Ju Youn Kim, Lily Q. Wang, Valentina C. Sladky, Tae Gyu Oh, Junlai Liu, Kaitlyn Trinh, Felix Eichin, Michael Downes, Mojgan Hosseini, Etienne D. Jacotot, Ronald M. Evans, Andreas Villunger, Michael Karin
Cell Metab. Author manuscript; available in PMC 2023 Oct 4.
Published in final edited form as: Cell Metab. 2022 Oct 4; 34(10): 1548–1560.e6. Published online 2022 Aug 29. doi: 10.1016/j.cmet.2022.08.005
PMCID:
PMC9547947
AbstractArticlePDF–3.3M
3.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
4.
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex
Pauline Antonie Ulmke, M. Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann, Huu Phuc Nguyen, Andre Fischer, Gregor Eichele, Jochen F. Staiger, Tran Tuoc
Stem Cell Reports. 2021 Apr 13; 16(4): 968–984. Published online 2021 Apr 1. doi: 10.1016/j.stemcr.2021.03.008
PMCID:
PMC8072132
AbstractArticlePDF–8.1M
5.
Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability
Taimoor I. Sheikh, Nasim Vasli, Stephen Pastore, Kimia Kharizi, Ricardo Harripaul, Zohreh Fattahi, Shruti Pande, Farooq Naeem, Abrar Hussain, Asif Mir, Omar Islam, Katta Mohan Girisha, Muhammad Irfan, Muhammad Ayub, Christoph Schwarzer, Hossein Najmabadi, Anju Shukla, Valentina C. Sladky, Vincent Zoran Braun, Irmina Garcia-Carpio, Andreas Villunger, John B. Vincent
Transl Psychiatry. 2021; 11: 1. Published online 2021 Jan 5. doi: 10.1038/s41398-020-01158-w
PMCID:
PMC7791037
AbstractArticlePDF–1.5M
6.
The spatiotemporal pattern and intensity of p53 activation during embryogenesis dictates phenotypic diversity in p53-driven developmental syndromes
Margot E. Bowen, Jacob McClendon, Hannah K. Long, Aryo Sorayya, Jeanine L. Van Nostrand, Joanna Wysocka, Laura D. Attardi
Dev Cell. Author manuscript; available in PMC 2020 Jul 22.
Published in final edited form as: Dev Cell. 2019 Jul 22; 50(2): 212–228.e6. Published online 2019 Jun 6. doi: 10.1016/j.devcel.2019.05.015
PMCID:
PMC6650355
AbstractArticlePDF–4.1M
7.
NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus
Kiyohiro Ando, Melissa J. Parsons, Richa B. Shah, Chloé I. Charendoff, Sheré L. Paris, Peter H. Liu, Sara R. Fassio, Brittany A. Rohrman, Ruth Thompson, Andrew Oberst, Samuel Sidi, Lisa Bouchier-Hayes
J Cell Biol. 2017 Jun 5; 216(6): 1795–1810. doi: 10.1083/jcb.201608095
PMCID:
PMC5461015
AbstractArticlePDF–2.8M
8.
The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd
L Peintner, L Dorstyn, S Kumar, T Aneichyk, A Villunger, C Manzl
Cell Death Differ. 2015 Nov; 22(11): 1803–1811. Published online 2015 Apr 10. doi: 10.1038/cdd.2015.31
PMCID:
PMC4648327
AbstractArticlePDF–1.8M
9.
Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage
F J Bock, G Krumschnabel, C Manzl, L Peintner, M C Tanzer, N Hermann-Kleiter, G Baier, L Llacuna, J Yelamos, A Villunger
Cell Death Differ. 2013 Apr; 20(4): 546–557. Published online 2012 Dec 14. doi: 10.1038/cdd.2012.152
PMCID:
PMC3595480
AbstractArticlePDF–1.9M
10.
PIDDosome-independent tumor suppression by Caspase-2
C Manzl, L Peintner, G Krumschnabel, F Bock, V Labi, M Drach, A Newbold, R Johnstone, Andreas Villunger
Cell Death Differ. 2012 Oct; 19(10): 1722–1732. Published online 2012 May 18. doi: 10.1038/cdd.2012.54
PMCID:
PMC3438502
AbstractArticlePDF–854K
11.
Neuronal caspase 2 activity and function requires RAIDD, but not PIDD
Elena M. Ribe, Ying Y. Jean, Rebecca L. Goldstein, Claudia Manzl, Leonidas Stefanis, Andreas Villunger, Carol M. Troy
Biochem J. 2012 Jun 15; 444(Pt 3): 591–599. Prepublished online 2012 Apr 19. Published online 2012 May 29. doi: 10.1042/BJ20111588
PMCID:
PMC3365438
AbstractArticlePDF–843K
12.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
13.
PIDD orchestrates translesion DNA synthesis in response to UV irradiation
E Logette, S Schuepbach-Mallepell, M J Eckert, X H Leo, B Jaccard, C Manzl, A Tardivel, A Villunger, M Quadroni, O Gaide, J Tschopp
Cell Death Differ. 2011 Jun; 18(6): 1036–1045. Published online 2011 Mar 18. doi: 10.1038/cdd.2011.19
PMCID:
PMC3131944
AbstractArticlePDF–547K
14.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
15.
Caspase-2 activation in the absence of PIDDosome formation
Claudia Manzl, Gerhard Krumschnabel, Florian Bock, Benedicte Sohm, Verena Labi, Florian Baumgartner, Emmanuelle Logette, Jürg Tschopp, Andreas Villunger
J Cell Biol. 2009 Apr 20; 185(2): 291–303. doi: 10.1083/jcb.200811105
PMCID:
PMC2700374
AbstractArticlePDF–3.5M
16.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
17.
Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD
Christina Berube, Louis-Martin Boucher, Weili Ma, Andrew Wakeham, Leonardo Salmena, Razqallah Hakem, Wen-Chen Yeh, Tak W. Mak, Samuel Benchimol
Proc Natl Acad Sci U S A. 2005 Oct 4; 102(40): 14314–14320. Published online 2005 Sep 23. doi: 10.1073/pnas.0506475102
PMCID:
PMC1242316
AbstractArticlePDF–507K
18.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
19.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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