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Items: 1 to 20 of 62

1.
MST1 knockdown inhibits osteoarthritis progression through Parkin‐mediated mitophagy and Nrf2/NF‐κB signalling pathway
Hantao Ye, Tingwen Cai, Yang Shen, Lin Zhao, Haojie Zhang, Jianxin Yang, Feida Li, Jiaoxiang Chen, Xiaolong Shui
J Cell Mol Med. 2024 Jun; 28(11): e18476. Published online 2024 Jun 6. doi: 10.1111/jcmm.18476
PMCID:
PMC11154837
AbstractArticlePDF–31M
2.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
3.
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes
Weijun Huang, Depeng Wu, Chaoyang Cai, Hui Yao, Zhenming Tian, Yang Yang, Mao Pang, Limin Rong, Bin Liu
Redox Biol. 2024 May; 71: 103104. Published online 2024 Feb 28. doi: 10.1016/j.redox.2024.103104
Correction in:
Redox Biol. 2024 Aug; 74: 103198.
PMCID:
PMC10914584
AbstractArticlePDF–17M
4.
Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions
Yana Xu, Meiyu Qu, Yangxun He, Qiangqiang He, Tingyu Shen, Jiahao Luo, Dan Tan, Hangyang Bao, Chengyun Xu, Xing Ji, Xinhua Hu, Muhammad Qasim Barkat, Ling-Hui Zeng, Ximei Wu
J Biol Chem. 2023 Dec; 299(12): 105395. Published online 2023 Oct 27. doi: 10.1016/j.jbc.2023.105395
PMCID:
PMC10696403
AbstractArticlePDF–5.4M
5.
Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice
Xinyu Cai, Yue Jiang, Zhiwen Cao, Mei Zhang, Na Kong, Lina Yu, Yedong Tang, Shuangbo Kong, Wenbo Deng, Haibin Wang, Jianxin Sun, Lijun Ding, Ruiwei Jiang, Haixiang Sun, Guijun Yan
eBioMedicine. 2023 Feb; 88: 104433. Published online 2023 Jan 7. doi: 10.1016/j.ebiom.2022.104433
PMCID:
PMC9841229
AbstractArticlePDF–3.2M
6.
Deficiency of MST1 in endometriosis related peritoneal macrophages promoted the autophagy of ectopic endometrial stromal cells by IL-10
Yufei Huang, Shumin Yan, Xiaoyu Dong, Xue Jiao, Shuang Wang, Dong Li, Guoyun Wang
Front Immunol. 2022; 13: 993788. Published online 2022 Oct 3. doi: 10.3389/fimmu.2022.993788
PMCID:
PMC9575673
AbstractArticlePDF–10M
7.
Regulation of MST complexes and activity via SARAH domain modifications
Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff
Biochem Soc Trans. Author manuscript; available in PMC 2022 Oct 7.
Published in final edited form as: Biochem Soc Trans. 2021 Apr 30; 49(2): 675–683. doi: 10.1042/BST20200559
PMCID:
PMC9540434
AbstractArticlePDF–485K
8.
Long noncoding RNA MST1P2 promotes cervical cancer progression by sponging with microRNA miR-133b
Rongrong Xu, Xiaoyue Zhang, Yan Xu, Junqin Wang, Zhihui Li, Xiaoming Cui
Bioengineered. 2021; 12(1): 1851–1860. Published online 2021 May 25. doi: 10.1080/21655979.2021.1921550
PMCID:
PMC8806230
AbstractArticlePDF–2.5M
9.
Apoptosis in Type 2 Diabetes: Can It Be Prevented? Hippo Pathway Prospects
Agnieszka Kilanowska, Agnieszka Ziółkowska
Int J Mol Sci. 2022 Jan; 23(2): 636. Published online 2022 Jan 7. doi: 10.3390/ijms23020636
PMCID:
PMC8775644
AbstractArticlePDF–834K
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
MST1 inhibits the progression of breast cancer by regulating the Hippo signaling pathway and may serve as a prognostic biomarker
Xiang Jin, Lihua Zhu, Sheng Xiao, Zhuhong Cui, Jing Tang, Jiangyong Yu, Mingjun Xie
Mol Med Rep. 2021 May; 23(5): 383. Published online 2021 Mar 18. doi: 10.3892/mmr.2021.12022
PMCID:
PMC7986037
AbstractArticlePDF–4.4M
12.
circCRAMP1L is a novel biomarker of preeclampsia risk and may play a role in preeclampsia pathogenesis via regulation of the MSP/RON axis in trophoblasts
Yonggang Zhang, Hongling Yang, Yipeng Zhang, Junzhu Shi, Ronggui Chen
BMC Pregnancy Childbirth. 2020; 20: 652. Published online 2020 Oct 27. doi: 10.1186/s12884-020-03345-5
PMCID:
PMC7590488
AbstractArticlePDF–4.1M
13.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
14.
Mst1 promotes mitochondrial dysfunction and apoptosis in oxidative stress-induced rheumatoid arthritis synoviocytes
Yingjie Wang, Qi Yang, Songpo Shen, Linjie Zhang, Yongbo Xiang, Xisheng Weng
Aging (Albany NY) 2020 Aug 31; 12(16): 16211–16223. Published online 2020 Jul 21. doi: 10.18632/aging.103643
PMCID:
PMC7485731
AbstractArticlePDF–2.3M
15.
The Legionella effector kinase LegK7 hijacks the host Hippo pathway to promote infection
Pei-Chung Lee, Matthias P. Machner
Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 8.
Published in final edited form as: Cell Host Microbe. 2018 Sep 12; 24(3): 429–438.e6. doi: 10.1016/j.chom.2018.08.004
PMCID:
PMC7343393
AbstractArticlePDF–1.5M
16.
MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer
Ethan L. Morgan, Molly R. Patterson, Emma L. Ryder, Siu Yi Lee, Christopher W. Wasson, Katherine L. Harper, Yigen Li, Stephen Griffin, G. Eric Blair, Adrian Whitehouse, Andrew Macdonald
PLoS Pathog. 2020 Jun; 16(6): e1008624. Published online 2020 Jun 18. doi: 10.1371/journal.ppat.1008624
PMCID:
PMC7326282
AbstractArticlePDF–3.5M
17.
FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis
S. Pauliina Turunen, Pernilla von Nandelstadh, Tiina Öhman, Erika Gucciardo, Brinton Seashore-Ludlow, Beatriz Martins, Ville Rantanen, Huini Li, Katrin Höpfner, Päivi Östling, Markku Varjosalo, Kaisa Lehti
Cell Death Differ. 2019 Dec; 26(12): 2577–2593. Published online 2019 Mar 22. doi: 10.1038/s41418-019-0321-x
PMCID:
PMC7224384
AbstractArticlePDF–3.7M
18.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
19.
POPX2 is a novel LATS phosphatase that regulates the Hippo pathway
Muhammad Bakhait Rahmat, Songjing Zhang, Cheng-Gee Koh
Oncotarget. 2019 Feb 19; 10(15): 1525–1538. Published online 2019 Feb 19. doi: 10.18632/oncotarget.26689
Correction in:
Oncotarget. 2019 Oct 8; 10(56): 5890–5891.
PMCID:
PMC6407677
AbstractArticlePDF–3.3M
20.
Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway
Hongyan Li, Jianxun Feng, Yunfang Zhang, Junxia Feng, Qi Wang, Shili Zhao, Ping Meng, Jingchun Li
Redox Biol. 2019 Jan; 20: 261–274. Published online 2018 Oct 19. doi: 10.1016/j.redox.2018.10.012
PMCID:
PMC6205415
AbstractArticlePDF–6.9M

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