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Items: 1 to 20 of 141

1.
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway
Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo
Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361
PMCID:
PMC11373599
AbstractArticlePDF–11M
2.
15-Deoxy-Δ12,14-prostaglandin-J2 reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1α degradation
Gemma Olmos, María I. Arenas, Raquel Bienes, María Jose Calzada, Julián Aragonés, Maria Laura Garcia-Bermejo, Manuel O. Landazuri, Javier Lucio-Cazaña
Cell Mol Life Sci. 2009 Jul; 66(13): 2167–2180. Published online 2009 May 21. doi: 10.1007/s00018-009-0039-x
PMCID:
PMC11115852
AbstractArticlePDF–657K
3.
LAMP2A regulates cisplatin resistance in colorectal cancer through mediating autophagy
Zhiliang Shi, Shuting Yang, Chenglong Shen, Jiazhe Shao, Fang Zhou, Haichen Liu, Guoqiang Zhou
J Cancer Res Clin Oncol. 2024; 150(5): 242. Published online 2024 May 8. doi: 10.1007/s00432-024-05775-6
PMCID:
PMC11078844
AbstractArticlePDF–5.0M
4.
Altered Splicing of LAMP2 in a Multigenerational Family from Latvia Affected by Danon Disease
Janis Stavusis, Ieva Micule, Ieva Grinfelde, Anna Zdanovica, Janis Pudulis, Sandra Valeina, Svetlana Sepetiene, Baiba Lace, Inna Inashkina
Medicina (Kaunas) 2024 Jan; 60(1): 99. Published online 2024 Jan 5. doi: 10.3390/medicina60010099
PMCID:
PMC10821070
AbstractArticlePDF–699K
5.
Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel
Jiyuan Zhang, Weizhong Zeng, Yan Han, Wan-Ru Lee, Jen Liou, Youxing Jiang
Mol Cell. Author manuscript; available in PMC 2024 Jul 20.
Published in final edited form as: Mol Cell. 2023 Jul 20; 83(14): 2524–2539.e7. Published online 2023 Jun 29. doi: 10.1016/j.molcel.2023.06.004
PMCID:
PMC10528928
AbstractArticlePDF–2.8M
6.
Identification and functional analysis of a novel de novo missense mutation located in the initiation codon of LAMP2 associated with early onset female Danon disease
Yongxiang Wang, Ming Bai, Piyi Zhang, Yu Peng, Zixian Chen, Zhiyu He, Jin Xu, Youqi Zhu, Dongdong Yan, Runqing Wang, Zheng Zhang
Mol Genet Genomic Med. 2023 Sep; 11(9): e2216. Published online 2023 Jun 8. doi: 10.1002/mgg3.2216
PMCID:
PMC10496070
AbstractArticlePDF–9.6M
7.
Danon Disease: Entire LAMP2 Gene Deletion with Unusual Clinical Presentation—Case Report and Review of the Literature
Adel Shalata, Marina Bar-Shai, Yarin Hadid, Muhammad Mahroum, Hila Mintz, Zaher Eldin Shalata, Evgeny Radzishevsky, Jacob Genizi, Avraham Lorber, Tamar Ben-Yosef, Liat Yaniv
Genes (Basel) 2023 Aug; 14(8): 1539. Published online 2023 Jul 27. doi: 10.3390/genes14081539
PMCID:
PMC10454823
AbstractArticlePDF–3.0M
8.
Identification of a novel splicing‐altering LAMP2 variant in a Chinese family with Danon disease
Di Fu, Shuai Wang, Yonghong Luo, Sha Wu, Daoquan Peng
ESC Heart Fail. 2023 Aug; 10(4): 2479–2486. Published online 2023 Jun 5. doi: 10.1002/ehf2.14417
PMCID:
PMC10375081
AbstractArticlePDF–1.0M
9.
Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma
Yatian Li, Zhenyue Gao, Yuhong Wang, Bo Pang, Binbin Zhang, Ruxin Hu, Yuqing Wang, Chao Liu, Xuebin Zhang, Jingxuan Yang, Mei Mei, Yongzhi Wang, Xuan Zhou, Min Li, Yu Ren
Nat Commun. 2023; 14: 4062. Published online 2023 Jul 10. doi: 10.1038/s41467-023-39845-z
PMCID:
PMC10333326
AbstractArticlePDF–6.5M
10.
AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity
Mario Ruiz, Ranjan Devkota, Delaney Kaper, Hanna Ruhanen, Kiran Busayavalasa, Uroš Radović, Marcus Henricsson, Reijo Käkelä, Jan Borén, Marc Pilon
J Biol Chem. 2023 Jun; 299(6): 104799. Published online 2023 May 8. doi: 10.1016/j.jbc.2023.104799
PMCID:
PMC10279913
AbstractArticlePDF–4.1M
11.
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805
Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang
Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558
PMCID:
PMC10240998
AbstractArticlePDF–4.4M
12.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
13.
Downregulation of Lysosome-Associated Membrane Protein-2A Contributes to the Pathogenesis of COPD
Yun-Jeong Jeong, Kyoung-Hee Lee, Jisu Woo, Ji Yeon Kim, Chang-Hoon Lee, Chul-Gyu Yoo
Int J Chron Obstruct Pulmon Dis. 2023; 18: 289–303. Published online 2023 Mar 14. doi: 10.2147/COPD.S378386
PMCID:
PMC10024500
AbstractArticlePDF–8.1M
14.
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice
Guohui Zhang, Chuan Jiang, Yushang Yang, Yan Wang, Haimeng Zhou, Siyu Dai, Mohan Liu, Yanting Yang, Li Yang, Qiongyan Shen, Tao Zhang, Xiaodong Zhang, Yihong Yang, Ying Shen
Cell Death Differ. 2023 Feb; 30(2): 500–514. Published online 2022 Dec 8. doi: 10.1038/s41418-022-01098-6
PMCID:
PMC9950085
AbstractArticlePDF–8.2M
15.
Metabolic Maturation Exaggerates Abnormal Calcium Handling in a Lamp2 Knockout Human Pluripotent Stem Cell-Derived Cardiomyocyte Model of Danon Disease
Robert J. Barndt, Qing Liu, Ying Tang, Michael P. Haugh, Jeffery Cui, Stephen Y. Chan, Haodi Wu
Biomolecules. 2023 Jan; 13(1): 69. Published online 2022 Dec 29. doi: 10.3390/biom13010069
PMCID:
PMC9855424
AbstractArticlePDF–5.4M
16.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
17.
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage
Jingyue Jia, Fulong Wang, Zambarlal Bhujabal, Ryan Peters, Michal Mudd, Thabata Duque, Lee Allers, Ruheena Javed, Michelle Salemi, Christian Behrends, Brett Phinney, Terje Johansen, Vojo Deretic
J Cell Biol. 2022 Nov 7; 221(11): e202207091. Published online 2022 Sep 30. doi: 10.1083/jcb.202207091
PMCID:
PMC9533235
AbstractArticlePDF–9.7M
18.
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold
Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo
Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134
PMCID:
PMC9475462
AbstractArticlePDF–4.6M
19.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
20.
Chaperone-mediated Autophagy Regulates Cell Growth by Targeting SMAD3 in Glioma
Hanqun Liu, Yuxuan Yong, Xingjian Li, Panghai Ye, Kai Tao, Guoyou Peng, Mingshu Mo, Wenyuan Guo, Xiang Chen, Yangfu Luo, Yuwan Lin, Jiewen Qiu, Zhiling Zhang, Liuyan Ding, Miaomiao Zhou, Xinling Yang, Lin Lu, Qian Yang, Pingyi Xu
Neurosci Bull. 2022 Jun; 38(6): 637–651. Published online 2022 Mar 10. doi: 10.1007/s12264-022-00818-9
PMCID:
PMC9206062
AbstractArticlePDF–3.0M

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