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Items: 1 to 20 of 33

1.
JMJD5 inhibits lung cancer progression by facilitating EGFR proteasomal degradation
Jing Shen, Guiling Liu, Hongyan Qi, Xueping Xiang, Jimin Shao
Cell Death Dis. 2023 Oct; 14(10): 657. Published online 2023 Oct 9. doi: 10.1038/s41419-023-06194-0
PMCID:
PMC10562424
AbstractArticlePDF–4.1M
2.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
3.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors
Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier
Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118
PMCID:
PMC8017720
AbstractArticlePDF–1.9M
6.
JMJD5 couples with CDK9 to release the paused RNA polymerase II
Haolin Liu, Srinivas Ramachandran, Nova Fong, Tzu Phang, Schuyler Lee, Pirooz Parsa, Xinjian Liu, Laura Harmacek, Thomas Danhorn, Tengyao Song, Sangphil Oh, Qianqian Zhang, Zhongzhou Chen, Qian Zhang, Ting-Hui Tu, Carrie Happoldt, Brian O’Conner, Ralf Janknecht, Chuan-Yuan Li, Philippa Marrack, John Kappler, Sonia Leach, Gongyi Zhang
Proc Natl Acad Sci U S A. 2020 Aug 18; 117(33): 19888–19895. Published online 2020 Aug 3. doi: 10.1073/pnas.2005745117
PMCID:
PMC7443887
AbstractArticlePDF–1.1M
7.
Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model
Cheng-Yu Yang, Chang-Huei Tsao, Cheng-Chih Hsieh, Chih-Kung Lin, Chun-Shu Lin, Yu-Hsuan Li, Wei-Chin Chang, Jen-Chen Cheng, Gu-Jiun Lin, Huey-Kang Sytwu, Yin-Lai Wang, Yuan-Wu Chen
PLoS One. 2020; 15(7): e0236101. Published online 2020 Jul 17. doi: 10.1371/journal.pone.0236101
PMCID:
PMC7367477
AbstractArticlePDF–1.8M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC
Hung-Jung Wang, Mamata Pochampalli, Ling-Yu Wang, June X Zou, Pei-Shan Li, Sheng-Chieh Hsu, Bi-Juan Wang, Shih-Han Huang, Ping Yang, Joy C. Yang, Cheng-Ying Chu, Chia-Ling Hsieh, Shian-Ying Sung, Chien-Feng Li, Clifford G. Tepper, David K. Ann, Allen C. Gao, Christopher P. Evans, Yoshihiro Izumiya, Chi-Pin Chuu, Wen-Ching Wang, Hong-Wu Chen, Hsing-Jien Kung
Oncogene. 2019; 38(1): 17–32. Published online 2018 Aug 2. doi: 10.1038/s41388-018-0414-x
PMCID:
PMC6755995
AbstractArticlePDF–3.8M
10.
JMJD5 links CRY1 function and proteasomal degradation
Anand R. Saran, Diana Kalinowska, Sangphil Oh, Ralf Janknecht, Luciano DiTacchio
PLoS Biol. 2018 Nov; 16(11): e2006145. Published online 2018 Nov 30. doi: 10.1371/journal.pbio.2006145
Correction in:
PLoS Biol. 2019 Aug; 17(8): e3000454.
PMCID:
PMC6291157
AbstractArticlePDF–2.3M
11.
JMJD5 is a human arginyl C-3 hydroxylase
Sarah E. Wilkins, Md. Saiful Islam, Joan M. Gannon, Suzana Markolovic, Richard J. Hopkinson, Wei Ge, Christopher J. Schofield, Rasheduzzaman Chowdhury
Nat Commun. 2018; 9: 1180. Published online 2018 Mar 21. doi: 10.1038/s41467-018-03410-w
Correction in:
Nat Commun. 2018; 9: 1675.
PMCID:
PMC5862942
AbstractArticlePDF–2.8M
12.
Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7
Haolin Liu, Chao Wang, Schuyler Lee, Fangkun Ning, Yang Wang, Qianqian Zhang, Zhongzhou Chen, Jianye Zang, Jay Nix, Shaodong Dai, Philippa Marrack, James Hagman, John Kappler, Gongyi Zhang
Sci Rep. 2018; 8: 3275. Published online 2018 Feb 19. doi: 10.1038/s41598-018-21432-8
PMCID:
PMC5818494
AbstractArticlePDF–1.7M
13.
JMJD5 cleaves monomethylated histone H3 N‐tail under DNA damaging stress
Jing Shen, Xueping Xiang, Lihan Chen, Haiyi Wang, Li Wu, Yanyun Sun, Li Ma, Xiuting Gu, Hong Liu, Lishun Wang, Ying‐nian Yu, Jimin Shao, Chao Huang, Y Eugene Chin
EMBO Rep. 2017 Dec; 18(12): 2131–2143. Published online 2017 Oct 6. doi: 10.15252/embr.201743892
PMCID:
PMC5709736
AbstractArticlePDF–2.0M
14.
Clipping of arginine-methylated histone tails by JMJD5 and JMJD7
Haolin Liu, Chao Wang, Schuyler Lee, Yu Deng, Matthew Wither, Sangphil Oh, Fangkun Ning, Carissa Dege, Qianqian Zhang, Xinjian Liu, Aaron M. Johnson, Jianye Zang, Zhongzhou Chen, Ralf Janknecht, Kirk Hansen, Philippa Marrack, Chuan-Yuan Li, John W. Kappler, James Hagman, Gongyi Zhang
Proc Natl Acad Sci U S A. 2017 Sep 12; 114(37): E7717–E7726. Published online 2017 Aug 28. doi: 10.1073/pnas.1706831114
PMCID:
PMC5604019
AbstractArticlePDF–3.2M
15.
A role for mitochondrial translation in promotion of viability in K-Ras mutant cells
Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge
Cell Rep. Author manuscript; available in PMC 2017 Aug 11.
Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061
PMCID:
PMC5553568
AbstractArticlePDF–1.8M
16.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
17.
Depletion of JMJD5 sensitizes tumor cells to microtubule-destabilizing agents by altering microtubule stability
Junyu Wu, Zhimin He, Da-Liang Wang, Fang-Lin Sun
Cell Cycle. 2016; 15(21): 2980–2991. Published online 2016 Oct 7. doi: 10.1080/15384101.2016.1234548
PMCID:
PMC5105934
AbstractArticlePDF–1.4M
18.
Widespread expansion of protein interaction capabilities by alternative splicing
Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal
Cell. Author manuscript; available in PMC 2017 Feb 11.
Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029
PMCID:
PMC4882190
AbstractArticlePDF–1.9M
19.
Epigenetic silencing of JMJD5 promotes the proliferation of hepatocellular carcinoma cells by down-regulating the transcription of CDKN1A
Bing-Hao Wu, Hui Chen, Chun-Miao Cai, Jia-Zhu Fang, Chong-Chao Wu, Li-Yu Huang, Lan Wang, Ze-Guang Han
Oncotarget. 2016 Feb 9; 7(6): 6847–6863. Published online 2016 Jan 9. doi: 10.18632/oncotarget.6867
PMCID:
PMC4872753
AbstractArticlePDF–6.8M
20.
JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis
Zhimin He, Junyu Wu, Xiaonan Su, Ye Zhang, Lixia Pan, Huimin Wei, Qiang Fang, Haitao Li, Da-Liang Wang, Fang-Lin Sun
J Biol Chem. 2016 Feb 26; 291(9): 4684–4697. Published online 2015 Dec 18. doi: 10.1074/jbc.M115.672642
PMCID:
PMC4813491
AbstractArticlePDF–4.2M

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