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Items: 1 to 20 of 31

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
3.
Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness
Christin Richter, Stephan Marquardt, Fanghua Li, Alf Spitschak, Nico Murr, Berdien A. H. Edelhäuser, George Iliakis, Brigitte M. Pützer, Stella Logotheti
J Exp Clin Cancer Res. 2019; 38: 292. Published online 2019 Jul 8. doi: 10.1186/s13046-019-1286-9
PMCID:
PMC6615232
AbstractArticlePDF–2.1M
4.
XLF and APLF bind to Ku80 on two remote sites to ensure DNA repair by non-homologous end-joining
Clement Nemoz, Virginie Ropars, Philippe Frit, Amandine Gontier, Pascal Drevet, Jinchao Yu, Raphaël Guerois, Aurelien Pitois, Audrey Comte, Christine Delteil, Nadia Barboule, Pierre Legrand, Sonia Baconnais, Yandong Yin, Satish Tadi, Emeline Barbet-Massin, Imre Berger, Eric Le Cam, Mauro Modesti, Eli Rothenberg, Patrick Calsou, Jean-Baptiste Charbonnier
Nat Struct Mol Biol. Author manuscript; available in PMC 2018 Nov 13.
Published in final edited form as: Nat Struct Mol Biol. 2018 Oct; 25(10): 971–980. Published online 2018 Oct 5. doi: 10.1038/s41594-018-0133-6
PMCID:
PMC6234012
AbstractArticlePDF–2.3M
5.
DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface
Ivan Corbeski, Klemen Dolinar, Hans Wienk, Rolf Boelens, Hugo van Ingen
Nucleic Acids Res. 2018 Aug 21; 46(14): 7138–7152. Published online 2018 Jun 14. doi: 10.1093/nar/gky507
PMCID:
PMC6101569
AbstractArticlePDF–5.3M
6.
PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
Qian Chen, Muzaffer Ahmad Kassab, Françoise Dantzer, Xiaochun Yu
Nat Commun. 2018; 9: 3233. Published online 2018 Aug 13. doi: 10.1038/s41467-018-05588-5
PMCID:
PMC6089979
AbstractArticlePDF–1.9M
7.
Enhanced expression of histone chaperone APLF associate with breast cancer
Aditi Majumder, Khaja Moheiddin Syed, Ananda Mukherjee, Manendra Babu Lankadasari, Juberiya Mohammed Azeez, Sreeharshan Sreeja, Kuzhuvelil B. Harikumar, Madhavan Radhakrishna Pillai, Debasree Dutta
Mol Cancer. 2018; 17: 76. Published online 2018 Mar 26. doi: 10.1186/s12943-018-0826-9
PMCID:
PMC5870250
AbstractArticlePDF–4.6M
8.
Characterization of the APLF FHA–XRCC1 phosphopeptide interaction and its structural and functional implications
Kyungmin Kim, Lars C. Pedersen, Thomas W. Kirby, Eugene F. DeRose, Robert E. London
Nucleic Acids Res. 2017 Dec 1; 45(21): 12374–12387. Published online 2017 Oct 20. doi: 10.1093/nar/gkx941
PMCID:
PMC5716189
AbstractArticlePDF–4.1M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity
Ian Gibbs-Seymour, Pietro Fontana, Johannes Gregor Matthias Rack, Ivan Ahel
Mol Cell. 2016 May 5; 62(3): 432–442. doi: 10.1016/j.molcel.2016.03.008
PMCID:
PMC4858568
AbstractArticlePDF–2.7M
11.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
12.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
13.
Tripartite Motif-containing 33 (TRIM33) Protein Functions in the Poly(ADP-ribose) Polymerase (PARP)-dependent DNA Damage Response through Interaction with Amplified in Liver Cancer 1 (ALC1) Protein
Atul Kulkarni, Jay Oza, Ming Yao, Honeah Sohail, Vasudeva Ginjala, Antonia Tomas-Loba, Zuzana Horejsi, Antoinette R. Tan, Simon J. Boulton, Shridar Ganesan
J Biol Chem. 2013 Nov 8; 288(45): 32357–32369. Published online 2013 Aug 6. doi: 10.1074/jbc.M113.459164
PMCID:
PMC3820871
AbstractArticlePDF–2.8M
14.
The F-box Protein FBXO25 Promotes the Proteasome-dependent Degradation of ELK-1 Protein
Felipe R. Teixeira, Adriana O. Manfiolli, Cláudia S. Soares, Munira M. A. Baqui, Tie Koide, Marcelo D. Gomes
J Biol Chem. 2013 Sep 27; 288(39): 28152–28162. Published online 2013 Aug 12. doi: 10.1074/jbc.M113.504308
PMCID:
PMC3784726
AbstractArticlePDF–856K
15.
Identification and Functional Characterization of a Ku-binding Motif in Aprataxin Polynucleotide Kinase/Phosphatase-like Factor (APLF)
Purnata Shirodkar, Amanda L. Fenton, Li Meng, C. Anne Koch
J Biol Chem. 2013 Jul 5; 288(27): 19604–19613. Published online 2013 May 20. doi: 10.1074/jbc.M112.440388
PMCID:
PMC3707661
AbstractArticlePDF–1.3M
16.
The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
Amanda L. Fenton, Purnata Shirodkar, Chloe J. Macrae, Li Meng, C. Anne Koch
Nucleic Acids Res. 2013 Apr; 41(7): 4080–4092. Published online 2013 Feb 28. doi: 10.1093/nar/gkt134
PMCID:
PMC3627606
AbstractArticlePDF–2.5M
17.
APLF promotes the assembly and activity of non-homologous end joining protein complexes
Gabrielle J Grundy, Stuart L Rulten, Zhihong Zeng, Raquel Arribas-Bosacoma, Natasha Iles, Katie Manley, Antony Oliver, Keith W Caldecott
EMBO J. 2013 Jan 9; 32(1): 112–125. Published online 2012 Nov 23. doi: 10.1038/emboj.2012.304
PMCID:
PMC3545299
AbstractArticlePDF–2.3M
18.
Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodelling enzyme ALC1
Dragana Ahel, Zuzana Hořejší, Nicola Wiechens, Sophie E. Polo, Elisa Garcia-Wilson, Ivan Ahel, Helen Flynn, Mark Skehel, Stephen C. West, Stephen P. Jackson, Tom Owen-Hughes, Simon J. Boulton
Science. Author manuscript; available in PMC 2012 Sep 17.
Published in final edited form as: Science. 2009 Sep 4; 325(5945): 1240–1243. Published online 2009 Aug 6. doi: 10.1126/science.1177321
PMCID:
PMC3443743
AbstractArticlePDF–1.4M
19.
DNA repair factor APLF is a histone chaperone
Pawan Vinod Mehrotra, Dragana Ahel, Daniel P. Ryan, Ria Weston, Nicola Wiechens, Rolf Kraehenbuehl, Tom Owen-Hughes, Ivan Ahel
Mol Cell. Author manuscript; available in PMC 2012 Sep 17.
Published in final edited form as: Mol Cell. 2011 Jan 7; 41(1): 46–55. doi: 10.1016/j.molcel.2010.12.008
PMCID:
PMC3443741
AbstractArticlePDF–2.4M
20.
Genomewide meta-analysis identifies novel multiple sclerosis susceptibility loci
Nikolaos A. Patsopoulos, the BSP MS Genetics working group and the steering committees of studies evaluating IFNb-1b and a CCR1-antagonist, ANZgene Consortium, GeneMSA, International Multiple Sclerosis Genetics Consortium, Paul I.W. de Bakker
Ann Neurol. Author manuscript; available in PMC 2012 Dec 1.
Published in final edited form as: Ann Neurol. 2011 Dec; 70(6): 897–912. doi: 10.1002/ana.22609
Correction in:
volume 73 on page 561
PMCID:
PMC3247076
AbstractArticlePDF–620K

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