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Items: 1 to 20 of 28

1.
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis
Boyuan Chen, Weihao Fu, Chunyang Jie, Guoxiu Zhang, Zhen Li, Yihai Liu, Shibo Zhou
Mol Med Rep. 2024 Jul; 30(1): 118. Published online 2024 May 14. doi: 10.3892/mmr.2024.13242
PMCID:
PMC11129537
AbstractArticlePDF–5.1M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Comprehensive analysis of epigenetics regulation, prognostic and the correlation with immune infiltrates of GPX7 in adult gliomas
Wallax Augusto Silva Ferreira, Glauco Akelinghton Freire Vitiello, Tiago da Silva Medina, Edivaldo Herculano Correa de Oliveira
Sci Rep. 2022; 12: 6442. Published online 2022 Apr 19. doi: 10.1038/s41598-022-10114-1
PMCID:
PMC9018725
AbstractArticlePDF–87M
4.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord
Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6
PMCID:
PMC8760077
AbstractArticlePDF–12M
5.
GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway
Xuchen Hu, Boer Li, Fanzi Wu, Xiaoyu Liu, Mengyu Liu, Chenglin Wang, Yu Shi, Ling Ye
J Cell Mol Med. 2021 Nov; 25(22): 10454–10465. Published online 2021 Oct 9. doi: 10.1111/jcmm.16974
PMCID:
PMC8581313
AbstractArticlePDF–2.2M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Characterization of the endoplasmic reticulum–resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding
Shingo Kanemura, Elza Firdiani Sofia, Naoya Hirai, Masaki Okumura, Hiroshi Kadokura, Kenji Inaba
J Biol Chem. 2020 Sep 4; 295(36): 12772–12785. Published online 2020 Jul 21. doi: 10.1074/jbc.RA120.013607
PMCID:
PMC7476714
AbstractArticlePDF–3.0M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
HIV–host interactome revealed directly from infected cells
Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed, Tommy Tong, Sarah Keegan, James M. Binley, Ileana M. Cristea, David Fenyö, Michael P. Rout, Brian T. Chait, Mark A. Muesing
Nat Microbiol. Author manuscript; available in PMC 2016 Jul 1.
Published in final edited form as: Nat Microbiol. 2016 Jul; 1(7): 16068. Published online 2016 May 23. doi: 10.1038/nmicrobiol.2016.68
PMCID:
PMC4928716
AbstractArticlePDF–1.1M
11.
GPX4 and GPX7 Over-Expression in Human Hepatocellular Carcinoma Tissues
E. Guerriero, F. Capone, M. Accardo, A. Sorice, M. Costantini, G. Colonna, G. Castello, S. Costantini
Eur J Histochem. 2015 Oct 26; 59(4): 2540. Published online 2015 Dec 1. doi: 10.4081/ejh.2015.2540
PMCID:
PMC4698610
AbstractArticlePDF–2.1M
12.
NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress
Po-Jen Chen, Jui-Yun Weng, Pang-Hung Hsu, Jin-Yuh Shew, Yi-Shuian Huang, Wen-Hwa Lee
Nucleic Acids Res. 2015 Oct 30; 43(19): 9393–9404. Published online 2015 Oct 7. doi: 10.1093/nar/gkv1010
PMCID:
PMC4627054
AbstractArticlePDF–2.0M
13.
Candidate pathway-based genetic association study of Platinum and Platinum-Taxane Related Toxicity in a Cohort of Primary Lung Cancer Patients
Cassandra Johnson, Vernon S. Pankratz, Ana I. Velazquez, Jeremiah A. Aakre, Charles L. Loprinzi, Nathan P. Staff, Anthony J. Windebank, Ping Yang
J Neurol Sci. Author manuscript; available in PMC 2016 Feb 15.
Published in final edited form as: J Neurol Sci. 2015 Feb 15; 349(0): 124–128. Published online 2015 Jan 5. doi: 10.1016/j.jns.2014.12.041
PMCID:
PMC4334320
AbstractArticlePDF–260K
14.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
15.
Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett’s carcinogenesis
Dun-Fa Peng, Tian-Ling Hu, Mohammed Soutto, Abbes Belkhiri, Wael El-Rifai
Carcinogenesis. 2014 Jul; 35(7): 1620–1628. Published online 2014 Apr 1. doi: 10.1093/carcin/bgu083
PMCID:
PMC4076814
AbstractArticlePDF–2.8M
16.
Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human
Yi-Cheng Chang, Yu-Hsiang Yu, Jin-Yuh Shew, Wei-Jei Lee, Juey-Jen Hwang, Yen-Hui Chen, Yet-Ran Chen, Pei-Chi Wei, Lee-Ming Chuang, Wen-Hwa Lee
EMBO Mol Med. 2013 Aug; 5(8): 1165–1179. Published online 2013 Jul 4. doi: 10.1002/emmm.201302679
PMCID:
PMC3944459
AbstractArticlePDF–1.3M
17.
Glutathione Peroxidase 7 Utilizes Hydrogen Peroxide Generated by Ero1α to Promote Oxidative Protein Folding
Lei Wang, Lihui Zhang, Yingbo Niu, Roberto Sitia, Chih-chen Wang
Antioxid Redox Signal. 2014 Feb 1; 20(4): 545–556. doi: 10.1089/ars.2013.5236
PMCID:
PMC3901321
AbstractArticlePDF–850K
18.
Glutathione peroxidase 7 has potential tumor suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma
DunFa Peng, TianLing Hu, Mohammed Soutto, Abbes Belkhiri, Alexander Zaika, Wael El-Rifai
Gut. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Gut. 2014 Apr; 63(4): 540–551. Published online 2013 Apr 12. doi: 10.1136/gutjnl-2013-304612
PMCID:
PMC3825783
AbstractArticlePDF–6.2M
19.
Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease
Pei-Chi Wei, Yi-Hsuan Hsieh, Mei-I Su, X-J Jiang, Pang-Hung Hsu, Wen-Ting Lo, Yung-Ming Jeng, Ju-Ming Wang, Phang-lang Chen, Yi-Cheng Chang, Kuo-Fen Lee, Ming-Daw Tsai, Jin-Yuh Shew, Wen-Hwa Lee
Mol Cell. Author manuscript; available in PMC 2013 Dec 14.
Published in final edited form as: Mol Cell. 2012 Dec 14; 48(5): 747–759. Published online 2012 Nov 1. doi: 10.1016/j.molcel.2012.10.007
PMCID:
PMC3582359
AbstractArticlePDF–5.6M
20.
Glutathione Peroxidase 7 Protects Against Oxidative DNA Damage in Oesophageal Cells
DunFa Peng, Abbes Belkhiri, TianLing Hu, Rupesh Chaturvedi, Mohammad Asim, Keith T. Wilson, Alexander Zaika, Wael El-Rifai
Gut. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: Gut. 2012 Sep; 61(9): 1250–1260. Published online 2011 Dec 9. doi: 10.1136/gutjnl-2011-301078
PMCID:
PMC3419307
AbstractArticlePDF–6.0M

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