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Select item 80841601.

Castration causes an increase in lysosomal size and upregulation of cathepsin D expression in principal cells along with increased secretion of procathepsin D and prosaposin oligomers in adult rat epididymis

Lorena Carvelli, Andrea Carolina Aguilera, Leila Zyla, Laura Lucía Pereyra, Carlos R. Morales, Louis Hermo, Miguel A. Sosa

PLoS One. 2021; 16(4): e0250454. Published online 2021 Apr 29. doi: 10.1371/journal.pone.0250454

PMCID:: PMC8084160

Abstract Article PDF–5.3M

Select item 70018672.

Cathepsin D plays a role in endothelial–pericyte interactions during alteration of the blood–retinal barrier in diabetic retinopathy

Finny Monickaraj, Paul McGuire, Arup Das

FASEB J. 2018 May; 32(5): 2539–2548. Published online 2018 Jan 8. doi: 10.1096/fj.201700781RR

PMCID:: PMC7001867

Abstract Article

Select item 69411913.

Hyperglycemia-induced cardiomyocyte death is mediated by lysosomal membrane injury and aberrant expression of Cathepsin D

Satoru Kobayashi, Fengyi Zhao, Tamayo Kobayashi, Mariko Hagiwara, Amanda Kaminaris, Cairong Li, Fei Cai, Yuan Huang, Qiangrong Liang

Biochem Biophys Res Commun. Author manuscript; available in PMC 2020 Dec 16.

Published in final edited form as: Biochem Biophys Res Commun. 2019 Dec 17 : S0006-291X(19)32371-X. Published online 2019 Dec 17. doi: 10.1016/j.bbrc.2019.12.051

PMCID:: PMC6941191

Abstract Article PDF–1.1M

Select item 48728794.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

Javier Barallobre-Barreiro, Rahmi Oklu, Marc Lynch, Marika Fava, Ferheen Baig, Xiaoke Yin, Temo Barwari, David N. Potier, Hassan Albadawi, Marjan Jahangiri, Karen E. Porter, Michael T. Watkins, Sanjay Misra, Julianne Stoughton, Manuel Mayr

Cardiovasc Res. 2016 Jun 1; 110(3): 419–430. Published online 2016 Apr 11. doi: 10.1093/cvr/cvw075

PMCID:: PMC4872879

Abstract Article PDF–1.1M

Select item 45768585.

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu

J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029

PMCID:: PMC4576858

Abstract Article PDF–3.0M

Select item 43514086.

Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

Aaron Ciechanover, Yong Tae Kwon

Exp Mol Med. 2015 Mar; 47(3): e147. Published online 2015 Mar 13. doi: 10.1038/emm.2014.117

PMCID:: PMC4351408

Abstract Article PDF–1.6M

Select item 43304577.

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

Christian Fork, Juliane Hitzel, Benjamin J. Nichols, Ritva Tikkanen, Ralf P. Brandes

Basic Res Cardiol. 2014; 109(6): 439. Published online 2014 Sep 10. doi: 10.1007/s00395-014-0439-4

PMCID:: PMC4330457

Abstract Article PDF–3.6M

Select item 37735058.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 293811410.

Proteomics Characterization of Extracellular Space Components in the Human Aorta

Athanasios Didangelos, Xiaoke Yin, Kaushik Mandal, Mark Baumert, Marjan Jahangiri, Manuel Mayr

Mol Cell Proteomics. 2010 Sep; 9(9): 2048–2062. Published online 2010 Jun 15. doi: 10.1074/mcp.M110.001693

PMCID:: PMC2938114

Abstract Article PDF–700K

Select item 276213911.

Mice Lacking Mannose 6-Phosphate Uncovering Enzyme Activity Have a Milder Phenotype than Mice Deficient for N-Acetylglucosamine-1-Phosphotransferase Activity

Marielle Boonen, Peter Vogel, Kenneth A. Platt, Nancy Dahms, Stuart Kornfeld

Mol Biol Cell. 2009 Oct 15; 20(20): 4381–4389. doi: 10.1091/mbc.E09-05-0398

PMCID:: PMC2762139

Abstract Article PDF–686K

Select item 273945212.

Nogo-B Receptor stabilizes Niemann-Pick Type C2 protein and regulates intracellular cholesterol trafficking

Kenneth D. Harrison, Robert Qing Miao, Carlos Fernandez-Hernándo, Yajaira Suárez, Alberto Dávalos, William C. Sessa

Cell Metab. Author manuscript; available in PMC 2010 Sep 1.

Published in final edited form as: Cell Metab. 2009 Sep; 10(3): 208–218. doi: 10.1016/j.cmet.2009.07.003

PMCID:: PMC2739452

Abstract Article PDF–3.7M

Select item 269239113.

Regulated renin release from 3T3-L1 adipocytes

Jason D. Fowler, Nathan D. Johnson, Thomas A. Haroldson, Joy A. Brintnall, Julio E. Herrera, Stephen A. Katz, David A. Bernlohr

Am J Physiol Endocrinol Metab. 2009 Jun; 296(6): E1383–E1391. Published online 2009 Mar 17. doi: 10.1152/ajpendo.00025.2009

PMCID:: PMC2692391

Abstract Article

Select item 263705014.

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper

J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406

PMCID:: PMC2637050

Abstract Article

Select item 248822215.

Prolactin Promotes the Secretion of Active Cathepsin D at the Basal Side of Rat Mammary Acini

Roberta Castino, Serge Delpal, Edwige Bouguyon, Marina Demoz, Ciro Isidoro, Michèle Ollivier-Bousquet

Endocrinology. 2008 Aug; 149(8): 4095–4105. Published online 2008 Apr 17. doi: 10.1210/en.2008-0249

PMCID:: PMC2488222

Abstract Article

Select item 219615116.

Natural Resistance to Infection with Intracellular Pathogens: The Nramp1 Protein Is Recruited to the Membrane of the Phagosome

Samantha Gruenheid, Elhanan Pinner, Michel Desjardins, Philippe Gros

J Exp Med. 1997 Feb 17; 185(4): 717–730. doi: 10.1084/jem.185.4.717

PMCID:: PMC2196151

Abstract Article PDF–439K

Select item 217201417.

Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Cary Esselens, Viola Oorschot, Veerle Baert, Tim Raemaekers, Kurt Spittaels, Lutgarde Serneels, Hui Zheng, Paul Saftig, Bart De Strooper, Judith Klumperman, Wim Annaert

J Cell Biol. 2004 Sep 27; 166(7): 1041–1054. doi: 10.1083/jcb.200406060

PMCID:: PMC2172014

Abstract Article PDF–6.5M

Select item 186726418.

Differential Expression of Cysteine and Aspartic Proteases during Progression of Atherosclerosis in Apolipoprotein E-Deficient Mice

Sofia Jormsjö, Dirk M. Wuttge, Allan Sirsjö, Carl Whatling, Anders Hamsten, Sten Stemme, Per Eriksson

Am J Pathol. 2002 Sep; 161(3): 939–945. doi: 10.1016/S0002-9440(10)64254-X

PMCID:: PMC1867264

Abstract Article PDF–643K

Select item 185071019.

Microinjection of Cathepsin D Induces Caspase-Dependent Apoptosis in Fibroblasts

Karin Roberg, Katarina Kågedal, Karin Öllinger

Am J Pathol. 2002 Jul; 161(1): 89–96. doi: 10.1016/S0002-9440(10)64160-0

PMCID:: PMC1850710

Abstract Article PDF–850K

Select item 53929720.

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis

Elisa Fossale, Pavlina Wolf, Janice A Espinola, Tanya Lubicz-Nawrocka, Allison M Teed, Hanlin Gao, Dorotea Rigamonti, Elena Cattaneo, Marcy E MacDonald, Susan L Cotman

BMC Neurosci. 2004; 5: 57. Published online 2004 Dec 10. doi: 10.1186/1471-2202-5-57