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Select item 113273671.

Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis

Stephen Huang, Casie Reed, Melissa Ilsley, Graham Magor, Michael Tallack, Michael Landsberg, Helen Mitchell, Kevin Gillinder, Andrew Perkins

Nat Commun. 2024; 15: 7019. Published online 2024 Aug 15. doi: 10.1038/s41467-024-50579-4

PMCID:: PMC11327367

Abstract Article PDF–4.2M

Select item 111481872.

TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice

Hee Joo Kim, Jinsun Jang, Kunhee Na, Eun-Hui Lee, Hyeon-Jung Gu, Yoon Hee Lim, Seul-A Joo, Seung Eun Baek, Joo-Young Roh, Han-Joo Maeng, Yun Hak Kim, Young-Jae Lee, Byung-Chul Oh, YunJae Jung

Exp Mol Med. 2024 May; 56(5): 1164–1177. Published online 2024 May 1. doi: 10.1038/s12276-024-01225-y

PMCID:: PMC11148187

Abstract Article PDF–7.7M

Select item 109015133.

A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis

Pengfei Guo, Rebecca C Lim, Keshari Rajawasam, Tiffany Trinh, Hong Sun, Hui Zhang

eLife. 2024; 13: e86168. Published online 2024 Feb 12. doi: 10.7554/eLife.86168

PMCID:: PMC10901513

Abstract Article PDF–9.2M

Select item 108911544.

Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress

Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini

Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1

PMCID:: PMC10891154

Abstract Article PDF–2.6M

Select item 108766485.

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek

Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8

PMCID:: PMC10876648

Abstract Article PDF–10M

Select item 108131206.

Eosinophils Contribute to Oral Tolerance via Induction of RORγt-Positive Antigen-Presenting Cells and RORγt-Positive Regulatory T Cells

Shunjiro Kurihara, Kotaro Suzuki, Masaya Yokota, Takashi Ito, Yuki Hayashi, Ryo Kikuchi, Takahiro Kageyama, Kazuyuki Meguro, Shigeru Tanaka, Arifumi Iwata, Yoshiyuki Goto, Akira Suto, Hiroshi Nakajima

Biomolecules. 2024 Jan; 14(1): 89. Published online 2024 Jan 10. doi: 10.3390/biom14010089

PMCID:: PMC10813120

Abstract Article PDF–4.1M

Select item 105772787.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 105764708.

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

Kim E. Nichols, John D. Crispino, Mortimer Poncz, James G. White, Stuart H. Orkin, John M. Maris, Mitchell J. Weiss

Nat Genet. Author manuscript; available in PMC 2023 Oct 14.

Published in final edited form as: Nat Genet. 2000 Mar; 24(3): 266–270. doi: 10.1038/73480

PMCID:: PMC10576470

Abstract Article PDF–1.3M

Select item 105657819.

Hypereosinophilia causes progressive cardiac pathologies in mice

Nicola Laura Diny, Megan Kay Wood, Taejoon Won, Monica Vladut Talor, Clarisse Lukban, Djahida Bedja, Nadan Wang, Hannah Kalinoski, Abdel Daoud, C. Conover Talbot, Jr., Brian Leei Lin, Daniela Čiháková

iScience. 2023 Oct 20; 26(10): 107990. Published online 2023 Sep 21. doi: 10.1016/j.isci.2023.107990

PMCID:: PMC10565781

Abstract Article PDF–6.4M

Select item 1046512710.

TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung antiviral immunity

William D Jackson, Chiara Giacomassi, Sophie Ward, Amber Owen, Tiago C Luis, Sarah Spear, Kevin J Woollard, Cecilia Johansson, Jessica Strid, Marina Botto

eLife. 2023; 12: e85647. Published online 2023 Aug 11. doi: 10.7554/eLife.85647

PMCID:: PMC10465127

Abstract Article PDF–5.0M

Select item 1036007411.

Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA – GPR35 ligand-receptor system

Marco De Giovanni, Eric V. Dang, Kevin Chen, Jinping An, Hiten D. Madhani, Jason G. Cyster

Immunity. Author manuscript; available in PMC 2024 Jul 11.

Published in final edited form as: Immunity. 2023 Jul 11; 56(7): 1548–1560.e5. Published online 2023 Jun 5. doi: 10.1016/j.immuni.2023.05.006

PMCID:: PMC10360074

Abstract Article PDF–2.7M

Select item 1033626312.

Gata1s mutant mice display persistent defects in the erythroid lineage

Te Ling, Kevin Zhang, Jiayue Yang, Sandeep Gurbuxani, John D. Crispino

Blood Adv. 2023 Jul 11; 7(13): 3253–3264. Published online 2022 Nov 11. doi: 10.1182/bloodadvances.2022008124

PMCID:: PMC10336263

Abstract Article PDF–3.4M

Select item 992960813.

Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment

Sandra Fernandes, Neetu Srivastava, Chiara Pedicone, Raki Sudan, Elizabeth A. Luke, Otto M. Dungan, Angela Pacherille, Shea T. Meyer, Shawn Dormann, Stéphane Schurmans, Benedict J. Chambers, John D. Chisholm, William G. Kerr

iScience. 2023 Feb 17; 26(2): 106071. Published online 2023 Jan 28. doi: 10.1016/j.isci.2023.106071

PMCID:: PMC9929608

Abstract Article PDF–2.4M

Select item 981072714.

In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis

C. Biben, T. S. Weber, K. S. Potts, J. Choi, D. C. Miles, A. Carmagnac, T. Sargeant, C. A. de Graaf, K. A. Fennell, A. Farley, O. J. Stonehouse, M. A. Dawson, D. J. Hilton, S. H. Naik, S. Taoudi

Nat Commun. 2023; 14: 41. Published online 2023 Jan 3. doi: 10.1038/s41467-022-35744-x

PMCID:: PMC9810727

Abstract Article PDF–3.0M

Select item 969191615.

GATA1 controls numbers of hematopoietic progenitors and their response to autoimmune neuroinflammation

Daniel Hwang, Larissa Lumi Watanabe Ishikawa, Maryam S. Seyedsadr, Elisabeth Mari, Ezgi Kasimoglu, Ziver Sahin, Alexandra Boehm, Soohwa Jang, Javad Rasouli, Courtney Vaccaro, Michael Gonzalez, Hakon Hakonarson, Abdolmohamad Rostami, Guang-Xian Zhang, Bogoljub Ciric

Blood Adv. 2022 Dec 13; 6(23): 5980–5994. Published online 2022 Oct 10. doi: 10.1182/bloodadvances.2022008234

PMCID:: PMC9691916

Abstract Article PDF–3.7M

Select item 933804016.

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

Moïra Rossitto, Stephanie Déjardin, Chris M. Rands, Stephanie Le Gras, Roberta Migale, Mahmoud-Reza Rafiee, Yasmine Neirijnck, Alain Pruvost, Anvi Laetitia Nguyen, Guillaume Bossis, Florence Cammas, Lionel Le Gallic, Dagmar Wilhelm, Robin Lovell-Badge, Brigitte Boizet-Bonhoure, Serge Nef, Francis Poulat

Nat Commun. 2022; 13: 4412. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32061-1

PMCID:: PMC9338040

Abstract Article PDF–11M

Select item 920312917.

Differential Etv2 threshold requirement for endothelial and erythropoietic development

Tanvi Sinha, Kelly Lammerts van Bueren, Diane E. Dickel, Ivana Zlatanova, Reuben Thomas, Carlos O. Lizama, Shan-Mei Xu, Ann C. Zovein, Kohta Ikegami, Ivan P. Moskowitz, Katherine S. Pollard, Len A. Pennacchio, Brian L. Black

Cell Rep. Author manuscript; available in PMC 2022 Jun 16.

Published in final edited form as: Cell Rep. 2022 May 31; 39(9): 110881. doi: 10.1016/j.celrep.2022.110881

PMCID:: PMC9203129

Abstract Article PDF–2.0M

Select item 919752218.

Siglec-F–expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis

Seungwon Ryu, Jae Woo Shin, Soie Kwon, Jiwon Lee, Yong Chul Kim, Yoe-Sik Bae, Yong-Soo Bae, Dong Ki Kim, Yon Su Kim, Seung Hee Yang, Hye Young Kim

J Clin Invest. 2022 Jun 15; 132(12): e156876. Published online 2022 Jun 15. doi: 10.1172/JCI156876

PMCID:: PMC9197522

Abstract Article PDF–10M

Select item 911737619.

Zkscan3 affects erythroblast development by regulating the transcriptional activity of GATA1 and KLF1 in mice

Zixuan Li, Binjie Sheng, Tingting Zhang, Tian Wang, Dan Chen, Gangli An, Xingbing Wang, Huimin Meng, Lin Yang

J Mol Histol. 2022; 53(2): 423–436. Published online 2021 Dec 23. doi: 10.1007/s10735-021-10052-8

PMCID:: PMC9117376

Abstract Article PDF–4.3M

Select item 896154920.

Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in Gata1^low Mice

Maria Zingariello, Paola Verachi, Francesca Gobbo, Fabrizio Martelli, Mario Falchi, Maria Mazzarini, Mauro Valeri, Giuseppe Sarli, Christian Marinaccio, Johanna Melo-Cardenas, John D. Crispino, Anna Rita Migliaccio

Biomolecules. 2022 Feb; 12(2): 234. Published online 2022 Jan 30. doi: 10.3390/biom12020234