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Items: 1 to 20 of 51

1.
The miR-221/222 cluster regulates hematopoietic stem cell quiescence and multipotency by suppressing both Fos/AP-1/IEG pathway activation and stress-like differentiation to granulocytes
Peter K. Jani, Georg Petkau, Yohei Kawano, Uwe Klemm, Gabriela Maria Guerra, Gitta Anne Heinz, Frederik Heinrich, Pawel Durek, Mir-Farzin Mashreghi, Fritz Melchers
PLoS Biol. 2023 Nov; 21(11): e3002015. Published online 2023 Nov 20. doi: 10.1371/journal.pbio.3002015
PMCID:
PMC10695376
AbstractArticlePDF–3.3M
2.
Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activate Nrf2/HO-1 signaling pathway
Xue-jun Wang, Dan Zhang, Yan-ting Yang, Xiao-ying Li, Hong-na Li, Xiao-peng Zhang, Jun-yi Long, Yun-qiong Lu, Li Liu, Guang Yang, Jie Liu, Jue Hong, Huan-gan Wu, Xiao-peng Ma
Front Immunol. 2023; 14: 1089809. Published online 2023 Jan 27. doi: 10.3389/fimmu.2023.1089809
PMCID:
PMC9911687
AbstractArticlePDF–9.1M
3.
miR-222-3p is involved in neural tube closure by directly targeting Ddit4 in RA induced NTDs mouse model
Yuqing Sun, Juan Zhang, Yufei Wang, Lei Wang, Meiyan Song, Ajab Khan, Li Zhang, Bo Niu, Hong Zhao, Meining Li, Tiane Luo, Qiwei He, Xianghui Xie, Zhizhen Liu, Jun Xie
Cell Cycle. 2021; 20(22): 2372–2386. Published online 2021 Nov 15. doi: 10.1080/15384101.2021.1982506
PMCID:
PMC8794519
AbstractArticlePDF–2.2M
4.
Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4
Satoshi Yamaguchi, Dongxiao Zhang, Akihiro Katayama, Naoko Kurooka, Ryosuke Sugawara, Haya Hamed Hassan Albuayjan, Atsuko Nakatsuka, Jun Eguchi, Jun Wada
Front Endocrinol (Lausanne) 2021; 12: 750261. Published online 2022 Jan 3. doi: 10.3389/fendo.2021.750261
PMCID:
PMC8762293
AbstractArticlePDF–10M
5.
MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination
Eric J. Wigton, Yohei Mikami, Ryan J. McMonigle, Carlos A. Castellanos, Adam K. Wade-Vallance, Simon K. Zhou, Robin Kageyama, Adam Litterman, Suparna Roy, Daisuke Kitamura, Emily C. Dykhuizen, Christopher D.C. Allen, Hui Hu, John J. O’Shea, K. Mark Ansel
J Exp Med. 2021 Nov 1; 218(11): e20201422. Published online 2021 Sep 29. doi: 10.1084/jem.20201422
PMCID:
PMC8485858
AbstractArticlePDF–4.7M
6.
MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of Interleukin-23
Yohei Mikami, Rachael L. Philips, Giuseppe Sciumè, Franziska Petermann, Françoise Meylan, Hiroyuki Nagashima, Chen Yao, Fred P. Davis, Stephen R. Brooks, Hong-Wei Sun, Hayato Takahashi, Amanda C. Poholek, Han-Yu Shih, Behdad Afzali, Stefan A. Muljo, Markus Hafner, Yuka Kanno, John J. O’Shea
Immunity. Author manuscript; available in PMC 2022 Mar 9.
Published in final edited form as: Immunity. 2021 Mar 9; 54(3): 514–525.e6. Published online 2021 Mar 2. doi: 10.1016/j.immuni.2021.02.015
PMCID:
PMC8025838
AbstractArticlePDF–2.3M
7.
MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1
Tsai-Chun Lai, Tzu-Lin Lee, Yu-Chun Chang, Yu-Chen Chen, Shu-Rung Lin, Shu-Wha Lin, Chi-Ming Pu, Jaw-Shiun Tsai, Yuh-Lien Chen
Front Cell Dev Biol. 2020; 8: 569150. Published online 2020 Dec 3. doi: 10.3389/fcell.2020.569150
PMCID:
PMC7744807
AbstractArticlePDF–7.7M
8.
miR-221 and -222 target CACNA1C and KCNJ5 leading to altered cardiac ion channel expression and current density
Stephanie Binas, Maria Knyrim, Julia Hupfeld, Udo Kloeckner, Sindy Rabe, Sigrid Mildenberger, Katja Quarch, Nicole Strätz, Danny Misiak, Michael Gekle, Claudia Grossmann, Barbara Schreier
Cell Mol Life Sci. 2020 Mar; 77(5): 903–918. Published online 2019 Jul 16. doi: 10.1007/s00018-019-03217-y
PMCID:
PMC7058603
AbstractArticlePDF–1.5M
9.
Glycyrrhizin protects γ-irradiated mice from gut bacteria-associated infectious complications by improving miR-222-associated Gas5 RNA reduction in macrophages of the bacterial translocation site
Ichiaki Ito, Bradford D. Loucas, Sumihiro Suzuki, Makiko Kobayashi, Fujio Suzuki
J Immunol. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: J Immunol. 2020 Mar 1; 204(5): 1255–1262. Published online 2020 Jan 15. doi: 10.4049/jimmunol.1900949
PMCID:
PMC7033010
AbstractArticlePDF–992K
10.
miR-222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8
Yan-Yan Bai, Jun-Zhi Niu
Mol Med Rep. 2020 Mar; 21(3): 1145–1153. Published online 2019 Dec 23. doi: 10.3892/mmr.2019.10903
PMCID:
PMC7003054
AbstractArticlePDF–1.2M
11.
Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation
Emilio Rojas, Monica Martinez-Pacheco, Maria Alexandra Rodriguez-Sastre, Paulina Ramos-Espinosa, Mahara Valverde
PLoS One. 2020; 15(1): e0221681. Published online 2020 Jan 10. doi: 10.1371/journal.pone.0221681
PMCID:
PMC6953820
AbstractArticlePDF–1.2M
12.
Inhibition of miRNA-222-3p Relieves Staphylococcal Enterotoxin B-Induced Liver Inflammatory Injury by Upregulating Suppressors of Cytokine Signaling 1
Peng Zhang, Jingda Yu, Yifang Gui, Cui Sun, Weiping Han
Yonsei Med J. 2019 Nov 1; 60(11): 1093–1102. Published online 2019 Oct 17. doi: 10.3349/ymj.2019.60.11.1093
PMCID:
PMC6813146
AbstractArticlePDF–401K
13.
ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis
Xincai Zhang, Xiangting Gao, Jun Hu, Yuxin Xie, Yuanyi Zuo, Hongfei Xu, Shaohua Zhu
Int J Mol Sci. 2019 Jan; 20(2): 407. Published online 2019 Jan 18. doi: 10.3390/ijms20020407
PMCID:
PMC6359435
AbstractArticlePDF–3.5M
14.
Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice
Xiuli Jiang, Lei Jiang, Aijing Shan, Yutong Su, Yulong Cheng, Dalong Song, He Ji, Guang Ning, Weiqing Wang, Yanan Cao
EBioMedicine. 2018 Nov; 37: 307–321. Published online 2018 Oct 10. doi: 10.1016/j.ebiom.2018.09.051
PMCID:
PMC6284352
AbstractArticlePDF–7.8M
15.
Upregulation of miR-221 and -222 in response to increased extracellular signal-regulated kinases 1/2 activity exacerbates neointimal hyperplasia in diabetes mellitus
Daniel J. Lightell, Jr., Stephanie C. Moss, T. Cooper Woods
Atherosclerosis. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Atherosclerosis. 2018 Feb; 269: 71–78. Published online 2017 Dec 9. doi: 10.1016/j.atherosclerosis.2017.12.016
PMCID:
PMC5812823
AbstractArticlePDF–2.8M
16.
Identification of microRNA that represses IRS-1 expression in liver
Kaoru Ono, Motoyuki Igata, Tatsuya Kondo, Sayaka Kitano, Yuki Takaki, Satoko Hanatani, Masaji Sakaguchi, Rieko Goto, Takafumi Senokuchi, Junji Kawashima, Noboru Furukawa, Hiroyuki Motoshima, Eiichi Araki
PLoS One. 2018; 13(1): e0191553. Published online 2018 Jan 24. doi: 10.1371/journal.pone.0191553
PMCID:
PMC5783395
AbstractArticlePDF–1.7M
17.
Macrophage-derived apoptotic bodies promote the proliferation of the recipient cells via shuttling microRNA-221/222
Ziwen Zhu, Duo Zhang, Heedoo Lee, Aravind Ajakumar Menon, Jingxuan Wu, Kebin Hu, Yang Jin
J Leukoc Biol. 2017 Jun; 101(6): 1349–1359. Published online 2017 Mar 8. doi: 10.1189/jlb.3A1116-483R
PMCID:
PMC5433853
AbstractArticle
18.
Gastric Carcinogenesis in the miR-222/221 Transgenic Mouse Model
Boram Choi, Jieun Yu, Tae-Su Han, Young-Kook Kim, Keun Hur, Byeong-Cheol Kang, Woo-Ho Kim, Dae-Yong Kim, Hyuk-Joon Lee, V. Narry Kim, Han-Kwang Yang
Cancer Res Treat. 2017 Jan; 49(1): 150–160. Published online 2016 Jun 23. doi: 10.4143/crt.2015.462
PMCID:
PMC5266385
AbstractArticlePDF–4.3M
19.
Role of miR-222-3p in c-Src-Mediated Regulation of Osteoclastogenesis
Shinya Takigawa, Andy Chen, Qiaoqiao Wan, Sungsoo Na, Akihiro Sudo, Hiroki Yokota, Kazunori Hamamura
Int J Mol Sci. 2016 Feb; 17(2): 240. Published online 2016 Feb 16. doi: 10.3390/ijms17020240
PMCID:
PMC4783971
AbstractArticlePDF–3.5M
20.
Endothelial microparticles reduce ICAM-1 expression in a microRNA-222-dependent mechanism
Felix Jansen, Xiaoyan Yang, Katharina Baumann, David Przybilla, Theresa Schmitz, Anna Flender, Kathrin Paul, Adil Alhusseiny, Georg Nickenig, Nikos Werner
J Cell Mol Med. 2015 Sep; 19(9): 2202–2214. Published online 2015 Jun 17. doi: 10.1111/jcmm.12607
PMCID:
PMC4568925
AbstractArticlePDF–544K

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