PMC Links for GEO Profiles (Select 84505571) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107987374.

LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure

Muchen Wu, Jing Wu, Kai Liu, Minjie Jiang, Fang Xie, Xuehong Yin, Jushan Wu, Qinghua Meng

Chin Med J (Engl) 2024 Jan 20; 137(2): 190–199. Published online 2024 Jan 5. doi: 10.1097/CM9.0000000000002969

PMCID:: PMC10798737

Abstract Article PDF–9.7M

Select item 103078525.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 99682976.

Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation

Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee

Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y

PMCID:: PMC9968297

Abstract Article PDF–4.4M

Select item 99064287.

LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease

Mi Bai, Mengqiu Wu, Mingzhu Jiang, Jia He, Xu Deng, Shuang Xu, Jiaojiao Fan, Mengqiu Miao, Ting Wang, Yuting Li, Xiaowen Yu, Lin Wang, Yue Zhang, Songming Huang, Li Yang, Zhanjun Jia, Aihua Zhang

EMBO Mol Med. 2023 Feb; 15(2): e16581. Published online 2023 Jan 11. doi: 10.15252/emmm.202216581

PMCID:: PMC9906428

Abstract Article PDF–14M

Select item 98994058.

Sirt3 restricts tumor initiation via promoting LONP1 deacetylation and K63 ubiquitination

Liyi Wu, Xinyi Yan, Ruibo Sun, Ye Ma, Wanyu Yao, Baogui Gao, Qingyuan Zhang, Junxiong You, Hao Wang, Qinrui Han, Xuegang Sun

J Transl Med. 2023; 21: 81. Published online 2023 Feb 4. doi: 10.1186/s12967-023-03925-x

PMCID:: PMC9899405

Abstract Article PDF–2.2M

Select item 88504669.

Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength

Zhisheng Xu, Tingting Fu, Qiqi Guo, Danxia Zhou, Wanping Sun, Zheng Zhou, Xinyi Chen, Jingzi Zhang, Lin Liu, Liwei Xiao, Yujing Yin, Yuhuan Jia, Erkai Pang, Yuncong Chen, Xin Pan, Lei Fang, Min-sheng Zhu, Wenyong Fei, Bin Lu, Zhenji Gan

Nat Commun. 2022; 13: 894. Published online 2022 Feb 16. doi: 10.1038/s41467-022-28557-5

PMCID:: PMC8850466

Abstract Article PDF–8.1M

Select item 873323210.

The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals

Xiaoqiang Sheng, Chuanming Liu, Guijun Yan, Guangyu Li, Jingyu Liu, Yanjun Yang, Shiyuan Li, Zhongxun Li, Jidong Zhou, Xin Zhen, Yang Zhang, Zhenyu Diao, Yali Hu, Chuanhai Fu, Bin Yao, Chaojun Li, Yu Cao, Bin Lu, Zhongzhou Yang, Yingying Qin, Haixiang Sun, Lijun Ding

EBioMedicine. 2022 Jan; 75: 103790. Published online 2021 Dec 30. doi: 10.1016/j.ebiom.2021.103790

PMCID:: PMC8733232

Abstract Article PDF–4.2M

Select item 854603711.

Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene

Lu Qiao, Le Xu, Lan Yu, Julia Wynn, Rebecca Hernan, Xueya Zhou, Christiana Farkouh-Karoleski, Usha S. Krishnan, Julie Khlevner, Aliva De, Annette Zygmunt, Timothy Crombleholme, Foong-Yen Lim, Howard Needelman, Robert A. Cusick, George B. Mychaliska, Brad W. Warner, Amy J. Wagner, Melissa E. Danko, Dai Chung, Douglas Potoka, Przemyslaw Kosiński, David J. McCulley, Mahmoud Elfiky, Kenneth Azarow, Elizabeth Fialkowski, David Schindel, Samuel Z. Soffer, Jane B. Lyon, Jill M. Zalieckas, Badri N. Vardarajan, Gudrun Aspelund, Vincent P. Duron, Frances A. High, Xin Sun, Patricia K. Donahoe, Yufeng Shen, Wendy K. Chung

Am J Hum Genet. 2021 Oct 7; 108(10): 1964–1980. Published online 2021 Sep 20. doi: 10.1016/j.ajhg.2021.08.011

PMCID:: PMC8546037

Abstract Article PDF–1.6M

Select item 813677612.

DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion

Pedro Silva-Pinheiro, Carlos Pardo-Hernández, Aurelio Reyes, Lisa Tilokani, Anup Mishra, Raffaele Cerutti, Shuaifeng Li, Dieu-Hien Rozsivalova, Sebastian Valenzuela, Sukru A Dogan, Bradley Peter, Patricio Fernández-Silva, Aleksandra Trifunovic, Julien Prudent, Michal Minczuk, Laurence Bindoff, Bertil Macao, Massimo Zeviani, Maria Falkenberg, Carlo Viscomi

Nucleic Acids Res. 2021 May 21; 49(9): 5230–5248. Published online 2021 May 6. doi: 10.1093/nar/gkab282

Correction in:: Nucleic Acids Res. 2021 Oct 11; 49(18): 10803.

PMCID:: PMC8136776

Abstract Article PDF–8.7M

Select item 801695313.

Mitochondrial LonP1 protease is implicated in the degradation of unstable Parkinson's disease-associated DJ-1/PARK 7 missense mutants

Raúl Sánchez-Lanzas, José G. Castaño

Sci Rep. 2021; 11: 7320. Published online 2021 Apr 1. doi: 10.1038/s41598-021-86847-2

PMCID:: PMC8016953

Abstract Article PDF–1.9M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 735573715.

Impaired Mitochondrial Morphology and Functionality in Lonp1^wt/− Mice

Anna De Gaetano, Lara Gibellini, Elena Bianchini, Rebecca Borella, Sara De Biasi, Milena Nasi, Federica Boraldi, Andrea Cossarizza, Marcello Pinti

J Clin Med. 2020 Jun; 9(6): 1783. Published online 2020 Jun 8. doi: 10.3390/jcm9061783

PMCID:: PMC7355737

Abstract Article PDF–7.4M

Select item 677055116.

Global Proteome of LonP1^+/− Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes

Jana Key, Aneesha Kohli, Clea Bárcena, Carlos López-Otín, Juliana Heidler, Ilka Wittig, Georg Auburger

Int J Mol Sci. 2019 Sep; 20(18): 4523. Published online 2019 Sep 12. doi: 10.3390/ijms20184523

PMCID:: PMC6770551

Abstract Article PDF–960K

Select item 629804017.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 624418318.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 579902319.

Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue

Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce

Cell Syst. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017

PMCID:: PMC5799023

Abstract Article PDF–730K

Select item 579538820.

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck

Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470

PMCID:: PMC5795388

Abstract Article PDF–4.4M

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