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Items: 1 to 20 of 44

1.
Downregulation of HMGCS2 mediated AECIIs lipid metabolic alteration promotes pulmonary fibrosis by activating fibroblasts
Juntang Yang, Xin Pan, Min Xu, Yingge Li, Chenxi Liang, Lulu Liu, Zhongzheng Li, Lan Wang, Guoying Yu
Respir Res. 2024; 25: 176. Published online 2024 Apr 24. doi: 10.1186/s12931-024-02816-z
PMCID:
PMC11040761
AbstractArticlePDF–15M
2.
Hmgcs2 regulates M2 polarization of macrophages to repair myocardial injury induced by sepsis
Xiao-Zheng Zou, Jun-Feng Hao, Ming-Xiao Hou
Aging (Albany NY) 2023 Aug 15; 15(15): 7794–7810. Published online 2023 Aug 9. doi: 10.18632/aging.204944
PMCID:
PMC10457052
AbstractArticlePDF–1.6M
3.
TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine
Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova
Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452
PMCID:
PMC10253002
AbstractArticlePDF–2.4M
4.
LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease
Mi Bai, Mengqiu Wu, Mingzhu Jiang, Jia He, Xu Deng, Shuang Xu, Jiaojiao Fan, Mengqiu Miao, Ting Wang, Yuting Li, Xiaowen Yu, Lin Wang, Yue Zhang, Songming Huang, Li Yang, Zhanjun Jia, Aihua Zhang
EMBO Mol Med. 2023 Feb; 15(2): e16581. Published online 2023 Jan 11. doi: 10.15252/emmm.202216581
PMCID:
PMC9906428
AbstractArticlePDF–14M
5.
Metabolic Changes Associated with Cardiomyocyte Dedifferentiation Enable Adult Mammalian Cardiac Regeneration
Yuan-Yuan Cheng, Zachery Gregorich, Ray P. Prajnamitra, David J. Lundy, Ting-Yun Ma, Yu-Hsuan Huang, Yi-Chan Lee, Shu-Chian Ruan, Jen-Hao Lin, Po-Ju Lin, Chiung Wen Kuo, Peilin Chen, Yu-Ting Yan, Rong Tian, Timothy J. Kamp, Patrick C.H. Hsieh
Circulation. Author manuscript; available in PMC 2023 Dec 20.
Published in final edited form as: Circulation. 2022 Dec 20; 146(25): 1950–1967. Published online 2022 Nov 24. doi: 10.1161/CIRCULATIONAHA.122.061960
PMCID:
PMC9808601
AbstractArticlePDF–3.3M
6.
Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming
Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li
Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6
PMCID:
PMC9553951
AbstractArticlePDF–3.8M
7.
Single-cell roadmap of human gonadal development
Luz Garcia-Alonso, Valentina Lorenzi, Cecilia Icoresi Mazzeo, João Pedro Alves-Lopes, Kenny Roberts, Carmen Sancho-Serra, Justin Engelbert, Magda Marečková, Wolfram H. Gruhn, Rachel A. Botting, Tong Li, Berta Crespo, Stijn van Dongen, Vladimir Yu Kiselev, Elena Prigmore, Mary Herbert, Ashley Moffett, Alain Chédotal, Omer Ali Bayraktar, Azim Surani, Muzlifah Haniffa, Roser Vento-Tormo
Nature. 2022; 607(7919): 540–547. Published online 2022 Jul 6. doi: 10.1038/s41586-022-04918-4
PMCID:
PMC9300467
AbstractArticlePDF–23M
8.
Ketone body 3-hydroxybutyrate enhances adipocyte function
Shigeki Nishitani, Atsunori Fukuhara, Issei Tomita, Shinji Kume, Jihoon Shin, Yosuke Okuno, Michio Otsuki, Hiroshi Maegawa, Iichiro Shimomura
Sci Rep. 2022; 12: 10080. Published online 2022 Jun 16. doi: 10.1038/s41598-022-14268-w
PMCID:
PMC9203800
AbstractArticlePDF–1.5M
9.
Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis
Shaza Asif, Ri Youn Kim, Thet Fatica, Jordan Sim, Xiaoling Zhao, Yena Oh, Alix Denoncourt, Angela C. Cheung, Michael Downey, Erin E. Mulvihill, Kyoung-Han Kim
Mol Metab. 2022 Jul; 61: 101494. Published online 2022 Apr 12. doi: 10.1016/j.molmet.2022.101494
PMCID:
PMC9039870
AbstractArticlePDF–5.9M
10.
Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine
Christopher J. Terranova, Kristina M. Stemler, Praveen Barrodia, Sabrina L. Jeter-Jones, Zhongqi Ge, Marimar de la Cruz Bonilla, Ayush Raman, Chia-Wei Cheng, Kendra L. Allton, Emre Arslan, Ömer H. Yilmaz, Michelle C. Barton, Kunal Rai, Helen Piwnica-Worms
Cell Rep. Author manuscript; available in PMC 2021 Dec 13.
Published in final edited form as: Cell Rep. 2021 Nov 23; 37(8): 110044. doi: 10.1016/j.celrep.2021.110044
PMCID:
PMC8668154
AbstractArticlePDF–2.7M
11.
Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction
Nadja Gebert, Chia-Wei Cheng, Joanna M. Kirkpatrick, Domenico Di Fraia, Jina Yun, Patrick Schädel, Simona Pace, George B. Garside, Oliver Werz, K. Lenhard Rudolph, Henri Jasper, Ömer H. Yilmaz, Alessandro Ori
Cell Rep. Author manuscript; available in PMC 2020 Aug 25.
Published in final edited form as: Cell Rep. 2020 Apr 28; 31(4): 107565. doi: 10.1016/j.celrep.2020.107565
PMCID:
PMC7446723
AbstractArticlePDF–3.1M
12.
The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice
Stefan Bagheri-Fam, Huijun Chen, Sean Wilson, Katie Ayers, James Hughes, Frederique Sloan-Bena, Pierre Calvel, Gorjana Robevska, Beatriz Puisac, Kamila Kusz-Zamelczyk, Stefania Gimelli, Anna Spik, Jadwiga Jaruzelska, Alina Warenik-Szymankiewicz, Sultana Faradz, Serge Nef, Juan Pié, Paul Thomas, Andrew Sinclair, Dagmar Wilhelm
PLoS One. 2020; 15(1): e0227411. Published online 2020 Jan 7. doi: 10.1371/journal.pone.0227411
PMCID:
PMC6946174
AbstractArticlePDF–4.9M
13.
Ketone body signaling mediates intestinal stem cell homeostasis and adaptation to diet
Chia-Wei Cheng, Moshe Biton, Adam L. Haber, Nuray Gunduz, George Eng, Liam T. Gaynor, Surya Tripathi, Gizem Calibasi-Kocal, Steffen Rickelt, Vincent L. Butty, Marta Moreno, Ameena M Iqbal, Khristian E. Bauer-Rowe, Shinya Imada, Mehmet Sefa Ulutas, Constantine Mylonas, Mark T. Whary, Stuart S. Levine, Yasemin Basbinar, Richard O. Hynes, Mari Mino-Kenudson, Vikram Deshpande, Laurie A. Boyer, James G. Fox, Christopher Terranova, Kunal Rai, Helen Piwnica-Worms, Maria M. Mihaylova, Aviv Regev, Ömer H. Yilmaz
Cell. Author manuscript; available in PMC 2020 Aug 22.
Published in final edited form as: Cell. 2019 Aug 22; 178(5): 1115–1131.e15. doi: 10.1016/j.cell.2019.07.048
PMCID:
PMC6732196
AbstractArticlePDF–3.6M
14.
Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy
julie clar, Blandine Gri, Julien Calderaro, Marie-Christine Birling, Yann Herault, Peter Smith, Gilles Mithieux, Fabienne Rajas
Kidney Int. Author manuscript;
Published in final edited form as: Kidney Int. 2014 Oct 1; 86(4): 747–756. Published online 2014 Apr 9. doi: 10.1038/ki.2014.102
PMCID:
PMC5678048
AbstractArticle
15.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
16.
Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction
Mary AM Cleaton, Claire L Dent, Mark Howard, Jennifer A Corish, Isabelle Gutteridge, Ulla Sovio, Francesca Gaccioli, Nozomi Takahashi, Steven R Bauer, D Steven Charnock-Jones, Theresa L Powell, Gordon CS Smith, Anne C Ferguson–Smith, Marika Charalambous
Nat Genet. Author manuscript; available in PMC 2017 Jun 1.
Published in final edited form as: Nat Genet. 2016 Dec; 48(12): 1473–1480. Published online 2016 Oct 24. doi: 10.1038/ng.3699
PMCID:
PMC5373434
AbstractArticlePDF–1.3M
17.
CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs
Désirée Schatton, David Pla-Martin, Marie-Charlotte Marx, Henriette Hansen, Arnaud Mourier, Ivan Nemazanyy, Alberto Pessia, Peter Zentis, Teresa Corona, Vangelis Kondylis, Esther Barth, Astrid C. Schauss, Vidya Velagapudi, Elena I. Rugarli
J Cell Biol. 2017 Mar 6; 216(3): 675–693. doi: 10.1083/jcb.201607019
PMCID:
PMC5350512
AbstractArticlePDF–3.2M
18.
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355
PMCID:
PMC5045200
AbstractArticlePDF–2.9M
19.
A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo
Melda Şişecioğlu, Harun Budak, Lars Geffers, Murat Çankaya, Mehmet Çiftci, Christina Thaller, Gregor Eichele, Ömer İrfan Küfrevioğlu, Hasan Özdemir
J Lipid Res. 2015 Aug; 56(8): 1551–1559. doi: 10.1194/jlr.M059634
PMCID:
PMC4513996
AbstractArticlePDF–3.4M
20.
Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism
Terhi O. Helenius, Julia O. Misiorek, Joel H. Nyström, Lina E. Fortelius, Aida Habtezion, Jian Liao, M. Nadeem Asghar, Haiyan Zhang, Salman Azhar, M. Bishr Omary, Diana M. Toivola
Mol Biol Cell. 2015 Jun 15; 26(12): 2298–2310. doi: 10.1091/mbc.E14-02-0736
PMCID:
PMC4462946
AbstractArticlePDF–3.8M

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