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Select item 110622521.

Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event

Allison J. Greaney, Makayla K. Portley, Danielle O’Mard, Devorah Crown, Nolan K. Maier, Megan A. Mendenhall, Katrin D. Mayer-Barber, Stephen H. Leppla, Mahtab Moayeri

J Leukoc Biol. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: J Leukoc Biol. 2020 Sep; 108(3): 773–786. Published online 2020 May 18. doi: 10.1002/JLB.4HI0320-028R

PMCID:: PMC11062252

Article PDF–1.0M

Select item 106700002.

The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes

Markus Spurlock, Weijun An, Galina Reshetnikova, Rong Wen, Hua Wang, Michelle Braha, Gabriela Solis, Stefan Kurtenbach, Orlando J. Galindez, Juan Pablo de Rivero Vaccari, Tsung-Han Chou, Vittorio Porciatti, Valery I. Shestopalov

Cells. 2023 Nov; 12(22): 2626. Published online 2023 Nov 15. doi: 10.3390/cells12222626

PMCID:: PMC10670000

Article PDF–6.1M

Select item 92482823.

UVB-Induced Skin Autoinflammation Due to Nlrp1b Mutation and Its Inhibition by Anti-IL-1β Antibody

Yuya Murase, Takuya Takeichi, Jun Koseki, Yuki Miyasaka, Yoshinao Muro, Tamio Ohno, Teppei Shimamura, Masashi Akiyama

Front Immunol. 2022; 13: 876390. Published online 2022 Jun 17. doi: 10.3389/fimmu.2022.876390

PMCID:: PMC9248282

Article PDF–5.7M

Select item 86803364.

NLRP1 inflammasome involves in learning and memory impairments and neuronal damages during aging process in mice

Dan Sun, Guofang Gao, Bihua Zhong, Han Zhang, Shixin Ding, Zhenghao Sun, Yaodong Zhang, Weizu Li

Behav Brain Funct. 2021; 17: 11. Published online 2021 Dec 17. doi: 10.1186/s12993-021-00185-x

PMCID:: PMC8680336

Article PDF–16M

Select item 67610905.

Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production

Jonathan Salazar-León, Ana Laura Valdez-Hernández, Sara García-Jiménez, Luis Román-Domínguez, Enrique Huanosta-Murillo, Laura C. Bonifaz, Leonor Pérez-Martínez, Gustavo Pedraza-Alva

Sci Rep. 2019; 9: 13815. Published online 2019 Sep 25. doi: 10.1038/s41598-019-49546-7

PMCID:: PMC6761090

Article PDF–1.7M

Select item 66108626.

N-terminal degradation activates the NLRP1B inflammasome

Ashley J. Chui, Marian C. Okondo, Sahana D. Rao, Kuo Gai, Andrew R. Griswold, Darren C. Johnson, Daniel P. Ball, Cornelius Y. Taabazuing, Elizabeth L. Orth, Brooke A. Vittimberga, Daniel A. Bachovchin

Science. Author manuscript; available in PMC 2020 Apr 5.

Published in final edited form as: Science. 2019 Apr 5; 364(6435): 82–85. Published online 2019 Mar 14. doi: 10.1126/science.aau1208

PMCID:: PMC6610862

Article PDF–637K

Select item 58566107.

Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

Marian C. Okondo, Sahana D. Rao, Cornelius Y. Taabazuing, Ashley J. Chui, Sarah E. Poplawski, Darren C. Johnson, Daniel A. Bachovchin

Cell Chem Biol. Author manuscript; available in PMC 2019 Mar 15.

Published in final edited form as: Cell Chem Biol. 2018 Mar 15; 25(3): 262–267.e5. Published online 2018 Jan 27. doi: 10.1016/j.chembiol.2017.12.013

PMCID:: PMC5856610

Article PDF–838K

Select item 56490238.

Listeria monocytogenes and Shigella flexneri Activate the NLRP1B Inflammasome

Jana Neiman-Zenevich, Sarah Stuart, Mena Abdel-Nour, Stephen E. Girardin, Jeremy Mogridge

Infect Immun. 2017 Nov; 85(11): e00338-17. Prepublished online 2017 Aug 14. Published online 2017 Oct 18. doi: 10.1128/IAI.00338-17

PMCID:: PMC5649023

Article PDF–1002K

Select item 45637829.

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation

V Kaushal, R Dye, P Pakavathkumar, B Foveau, J Flores, B Hyman, B Ghetti, B H Koller, A C LeBlanc

Cell Death Differ. 2015 Oct; 22(10): 1676–1686. Published online 2015 Mar 6. doi: 10.1038/cdd.2015.16

PMCID:: PMC4563782

Article PDF–2.6M

Select item 426059410.

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function

Baptiste Guey, Mélanie Bodnar, Serge N. Manié, Aubry Tardivel, Virginie Petrilli

Proc Natl Acad Sci U S A. 2014 Dec 2; 111(48): 17254–17259. Published online 2014 Nov 17. doi: 10.1073/pnas.1415756111

PMCID:: PMC4260594

Article PDF–1.1M

Select item 392601111.

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

Nina Van Opdenbosch, Prajwal Gurung, Lieselotte Vande Walle, Amelie Fossoul, Thirumala-Devi Kanneganti, Mohamed Lamkanfi

Nat Commun. 2014 Feb 4; 5: 3209. Published online 2014 Feb 4. doi: 10.1038/ncomms4209

PMCID:: PMC3926011

Article PDF–2.1M

Select item 368855412.

Direct Proteolytic Cleavage of NLRP1B Is Necessary and Sufficient for Inflammasome Activation by Anthrax Lethal Factor

Joseph Chavarría-Smith, Russell E. Vance

PLoS Pathog. 2013 Jun; 9(6): e1003452. Published online 2013 Jun 20. doi: 10.1371/journal.ppat.1003452

PMCID:: PMC3688554

Article PDF–1.6M

Select item 364100513.

Transcriptional analysis of the three Nlrp1 paralogs in mice

Inka Sastalla, Devorah Crown, Seth L Masters, Andrew McKenzie, Stephen H Leppla, Mahtab Moayeri

BMC Genomics. 2013; 14: 188. Published online 2013 Mar 18. doi: 10.1186/1471-2164-14-188

PMCID:: PMC3641005

Article PDF–1.5M

Select item 363506714.

NLRP1 dependent pyroptosis leads to acute lung injury and morbidity in mice

Martina Kovarova, Pamela R. Hesker, Leigh Jania, MyTrang Nguyen, John N. Snouwaert, Zhidan Xiang, Stephen E. Lommatzsch, Max T. Huang, Jenny P.-Y. Ting, Beverly H. Koller

J Immunol. Author manuscript; available in PMC 2013 Aug 15.

Published in final edited form as: J Immunol. 2012 Aug 15; 189(4): 2006–2016. Published online 2012 Jun 29. doi: 10.4049/jimmunol.1201065

PMCID:: PMC3635067

Article PDF–2.5M

Select item 355380915.

Activation of the Nlrp1b Inflammasome by Reduction of Cytosolic ATP

Kuo-Chieh Liao, Jeremy Mogridge

Infect Immun. 2013 Feb; 81(2): 570–579. doi: 10.1128/IAI.01003-12

PMCID:: PMC3553809

Article PDF–1.3M

Select item 349586216.

Anthrax Lethal Factor Cleaves Mouse Nlrp1b in Both Toxin-Sensitive and Toxin-Resistant Macrophages

Kristina A. Hellmich, Jonathan L. Levinsohn, Rasem Fattah, Zachary L. Newman, Nolan Maier, Inka Sastalla, Shihui Liu, Stephen H. Leppla, Mahtab Moayeri

PLoS One. 2012; 7(11): e49741. Published online 2012 Nov 12. doi: 10.1371/journal.pone.0049741