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Select item 112110201.

Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors

Marco Bassetto, Alexander V. Kolesnikov, Dominik Lewandowski, Jianying Z. Kiser, Maximilian Halabi, David E. Einstein, Elliot H. Choi, Krzysztof Palczewski, Vladimir J. Kefalov, Philip D. Kiser

Cell Rep. Author manuscript; available in PMC 2024 Jun 27.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114143. Published online 2024 Apr 25. doi: 10.1016/j.celrep.2024.114143

PMCID:: PMC11211020

Abstract Article PDF–1.8M

Select item 111822962.

Iron overload and chelation modulates bisretinoid levels in the retina

Jin Zhao, Hye Jin Kim, Diego Montenegro, Josh L. Dunaief, Janet R. Sparrow

Front Ophthalmol (Lausanne) 2023; 3: 1305864. Published online 2023 Dec 22. doi: 10.3389/fopht.2023.1305864

PMCID:: PMC11182296

Abstract Article PDF–9.4M

Select item 111402083.

Conditional deletion of miR-204 and miR-211 in murine retinal pigment epithelium results in retinal degeneration

Samuel W. Du, Ravikiran Komirisetty, Dominik Lewandowski, Elliot H. Choi, Damian Panas, Susie Suh, Marcin Tabaka, Roxana A. Radu, Krzysztof Palczewski

J Biol Chem. 2024 Jun; 300(6): 107344. Published online 2024 May 4. doi: 10.1016/j.jbc.2024.107344

PMCID:: PMC11140208

Abstract Article PDF–5.5M

Select item 111057704.

Bardet–Biedl Syndrome proteins regulate cilia disassembly during tissue maturation

Sarita Rani Patnaik, Viola Kretschmer, Lena Brücker, Sandra Schneider, Ann-Kathrin Volz, Liliana del Rocio Oancea-Castillo, Helen Louise May-Simera

Cell Mol Life Sci. 2019 Feb; 76(4): 757–775. Published online 2018 Nov 16. doi: 10.1007/s00018-018-2966-x

PMCID:: PMC11105770

Abstract Article PDF–3.0M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107562126.

A simple, rapid fluorescent reporter-based method for detection of ectopic Cre recombinase expression in presumed retinal cell type-targeted mouse lines

Sriganesh Ramachandra Rao, Steven J. Fliesler

Exp Eye Res. Author manuscript; available in PMC 2023 Dec 29.

Published in final edited form as: Exp Eye Res. 2023 Oct; 235: 109637. Published online 2023 Aug 31. doi: 10.1016/j.exer.2023.109637

PMCID:: PMC10756212

Abstract Article PDF–1.3M

Select item 105304947.

Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia

Aleksander Tworak, Alexander V. Kolesnikov, John D. Hong, Elliot H. Choi, Jennings C. Luu, Grazyna Palczewska, Zhiqian Dong, Dominik Lewandowski, Matthew J. Brooks, Laura Campello, Anand Swaroop, Philip D. Kiser, Vladimir J. Kefalov, Krzysztof Palczewski

Cell Rep. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112982. Published online 2023 Aug 15. doi: 10.1016/j.celrep.2023.112982

PMCID:: PMC10530494

Abstract Article PDF–3.2M

Select item 103547298.

Gene Supplementation in Mice Heterozygous for the D477G RPE65 Variant Implicated in Autosomal Dominant Retinitis Pigmentosa

Kecia L. Feathers, Lin Jia, Naheed W. Khan, Alexander J. Smith, Jian-Xing Ma, Robin R. Ali, Debra A. Thompson

Hum Gene Ther. July 2023; 34(13-14): 639–648. Published online 2023 Jul 17. doi: 10.1089/hum.2022.240

PMCID:: PMC10354729

Abstract Article PDF–956K

Select item 102660389.

Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models

Yunlu Xue, Xiaomei Sun, Sean K. Wang, Gayle B. Collin, Vladimir J. Kefalov, Constance L. Cepko

Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2217885120. Published online 2023 May 30. doi: 10.1073/pnas.2217885120

PMCID:: PMC10266038

Abstract Article PDF–5.5M

Select item 1017429210.

Mouse all-cone retina models of Cav1.4 synaptopathy

Joseph G. Laird, Ariel Kopel, Colten K. Lankford, Sheila A. Baker

Front Mol Neurosci. 2023; 16: 1155955. Published online 2023 Apr 27. doi: 10.3389/fnmol.2023.1155955

PMCID:: PMC10174292

Abstract Article PDF–2.8M

Select item 991871911.

Galanin receptor 3 - a new pharmacological target in retina degeneration

Joseph T. Ortega, Tanu Parmar, Beata Jastrzebska

Pharmacol Res. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Pharmacol Res. 2023 Jan 21; 188: 106675. Published online 2023 Jan 21. doi: 10.1016/j.phrs.2023.106675

PMCID:: PMC9918719

Abstract Article PDF–2.8M

Select item 976934112.

Rapamycin Inhibits Light-Induced Necrosome Activation Occurring in Wild-Type, but not RPE65-Null, Mouse Retina

Chunfeng Lu, Songhua Li, Minghao Jin

Invest Ophthalmol Vis Sci. 2022 Dec; 63(13): 19. Published online 2022 Dec 19. doi: 10.1167/iovs.63.13.19

PMCID:: PMC9769341

Abstract Article PDF–1.7M

Select item 898373413.

In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

Elliot H. Choi, Susie Suh, Andrzej T. Foik, Henri Leinonen, Gregory A. Newby, Xin D. Gao, Samagya Banskota, Thanh Hoang, Samuel W. Du, Zhiqian Dong, Aditya Raguram, Sajeev Kohli, Seth Blackshaw, David C. Lyon, David R. Liu, Krzysztof Palczewski

Nat Commun. 2022; 13: 1830. Published online 2022 Apr 5. doi: 10.1038/s41467-022-29490-3

PMCID:: PMC8983734

Abstract Article PDF–5.7M

Select item 893121214.

The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation

Wenjing Wu, Yusuke Takahashi, Henry Younghwa Shin, Xiang Ma, Gennadiy Moiseyev, Jian-Xing Ma

Proc Natl Acad Sci U S A. 2022 Mar 15; 119(11): e2115202119. Published online 2022 Mar 10. doi: 10.1073/pnas.2115202119

PMCID:: PMC8931212

Abstract Article PDF–2.6M

Select item 875979515.

In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope

Jakub Boguslawski, Grazyna Palczewska, Slawomir Tomczewski, Jadwiga Milkiewicz, Piotr Kasprzycki, Dorota Stachowiak, Katarzyna Komar, Marcin J. Marzejon, Bartosz L. Sikorski, Arkadiusz Hudzikowski, Aleksander Głuszek, Zbigniew Łaszczych, Karol Karnowski, Grzegorz Soboń, Krzysztof Palczewski, Maciej Wojtkowski

J Clin Invest. 2022 Jan 18; 132(2): e154218. Published online 2022 Jan 18. doi: 10.1172/JCI154218

PMCID:: PMC8759795

Abstract Article PDF–1.7M

Select item 857784916.

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi, Young Hoon Sung, Katsuhiko Nishimori, Zbynek Kozmik, Han-Woong Lee, Jin Woo Kim

eLife. 2021; 10: e70079. Published online 2021 Oct 22. doi: 10.7554/eLife.70079

PMCID:: PMC8577849

Abstract Article PDF–10M

Select item 826234317.

An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease

Elliot H. Choi, Susie Suh, David E. Einstein, Henri Leinonen, Zhiqian Dong, Sriganesh Ramachandra Rao, Steven J. Fliesler, Seth Blackshaw, Minzhong Yu, Neal S. Peachey, Krzysztof Palczewski, Philip D. Kiser

JCI Insight. 2021 May 10; 6(9): e146604. Published online 2021 May 10. doi: 10.1172/jci.insight.146604

PMCID:: PMC8262343

Abstract Article PDF–11M

Select item 801959618.

Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity

Dai Le, Soyeon Lim, Kwang Wook Min, Joon Woo Park, Youjoung Kim, Taejeong Ha, Kyeong Hwan Moon, Kay-Uwe Wagner, Jin Woo Kim

Mol Cells. 2021 Mar 31; 44(3): 168–178. Published online 2021 Mar 28. doi: 10.14348/molcells.2021.0027

PMCID:: PMC8019596

Abstract Article PDF–34M

Select item 793698319.

Prolonged melanopsin-based photoresponses depend in part on RPE65 and cellular retinaldehyde-binding protein (CRALBP)

Krystal R. Harrison, Aaron N. Reifler, Andrew P. Chervenak, Kwoon Y. Wong

Curr Eye Res. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Curr Eye Res. 2021 Apr; 46(4): 515–523. Published online 2020 Sep 7. doi: 10.1080/02713683.2020.1815793

PMCID:: PMC7936983

Abstract Article PDF–1.2M

Select item 789166320.

A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs

Seoyoung Kang, Daniel Larbi, Monica Andrade, Sara Reardon, Thomas A. Reh, Stefanie G. Wohl

Front Cell Dev Biol. 2020; 8: 620459. Published online 2021 Jan 26. doi: 10.3389/fcell.2020.620459

PMCID:: PMC7891663

Abstract Article PDF–4.9M

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