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Items: 1 to 20 of 27

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA
Xiang Zhang, Huilong Yin, Xiaofang Zhang, Xunliang Jiang, Yongkang Liu, Haolin Zhang, Yingran Peng, Da Li, Yanping Yu, Jinbao Zhang, Shuli Cheng, Angang Yang, Rui Zhang
Nat Commun. 2022; 13: 7038. Published online 2022 Nov 17. doi: 10.1038/s41467-022-34808-2
PMCID:
PMC9671881
AbstractArticlePDF–6.4M
3.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
4.
LATS1 and LATS2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ
Jing Yi, Li Lu, Kilangsungla Yanger, Wenqi Wang, Bo Hwa Sohn, Ben Z. Stanger, Min Zhang, James F. Martin, Jaffer A. Ajani, Junjie Chen, Ju-Seog Lee, Shumei Song, Randy L. Johnson
Hepatology. Author manuscript; available in PMC 2018 Mar 22.
Published in final edited form as: Hepatology. 2016 Nov; 64(5): 1757–1772. Published online 2016 Sep 30. doi: 10.1002/hep.28768
PMCID:
PMC5863546
AbstractArticlePDF–873K
5.
Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice
Jose M. Irimia, Catalina M. Meyer, Dyann M. Segvich, Sneha Surendran, Anna A. DePaoli-Roach, Nuria Morral, Peter J. Roach
J Biol Chem. 2017 Jun 23; 292(25): 10455–10464. Published online 2017 May 8. doi: 10.1074/jbc.M117.786525
PMCID:
PMC5481557
AbstractArticlePDF–2.8M
6.
Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation
Sandip K. Bose, Irina Hutson, Charles A. Harris
Endocrinology. 2016 Dec; 157(12): 4943–4960. Published online 2016 Oct 18. doi: 10.1210/en.2016-1615
PMCID:
PMC5133352
AbstractArticle
7.
Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion
Kristen E. Syring, Kayla A. Boortz, James K. Oeser, Alessandro Ustione, Kenneth A. Platt, Melanie K. Shadoan, Owen P. McGuinness, David W. Piston, David R. Powell, Richard M. O'Brien
Endocrinology. 2016 Dec; 157(12): 4534–4541. Published online 2016 Oct 18. doi: 10.1210/en.2016-1573
PMCID:
PMC5133349
AbstractArticle
8.
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series
Caitlyn E. Bowman, Liang Zhao, Thomas Hartung, Michael J. Wolfgang
Mol Cell Biol. 2016 Aug 1; 36(15): 2089–2104. Prepublished online 2016 May 23. Published online 2016 Jul 14. doi: 10.1128/MCB.00166-16
PMCID:
PMC4946427
AbstractArticlePDF–3.4M
9.
Structural basis for the recruitment of glycogen synthase by glycogenin
Elton Zeqiraj, Xiaojing Tang, Roger W. Hunter, Mar García-Rocha, Andrew Judd, Maria Deak, Alexander von Wilamowitz-Moellendorff, Igor Kurinov, Joan J. Guinovart, Mike Tyers, Kei Sakamoto, Frank Sicheri
Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28): E2831–E2840. Published online 2014 Jun 30. doi: 10.1073/pnas.1402926111
PMCID:
PMC4104858
AbstractArticlePDF–1.7M
10.
Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
Alexander von Wilamowitz-Moellendorff, Roger W. Hunter, Mar García-Rocha, Li Kang, Iliana López-Soldado, Louise Lantier, Kashyap Patel, Mark W. Peggie, Carlos Martínez-Pons, Martin Voss, Joaquim Calbó, Patricia T.W. Cohen, David H. Wasserman, Joan J. Guinovart, Kei Sakamoto
Diabetes. 2013 Dec; 62(12): 4070–4082. Published online 2013 Nov 16. doi: 10.2337/db13-0880
PMCID:
PMC3837029
AbstractArticlePDF–2.1M
11.
PER2 promotes glucose storage to liver glycogen during feeding and acute fasting by inducing Gys2 PTG and GL expression
Fabio Zani, Ludovic Breasson, Barbara Becattini, Ana Vukolic, Jean-Pierre Montani, Urs Albrecht, Alessandro Provenzani, Juergen A. Ripperger, Giovanni Solinas
Mol Metab. 2013 Aug; 2(3): 292–305. Published online 2013 Jul 1. doi: 10.1016/j.molmet.2013.06.006
PMCID:
PMC3773838
AbstractArticlePDF–3.9M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
A Stratified Transcriptomics Analysis of Polygenic Fat and Lean Mouse Adipose Tissues Identifies Novel Candidate Obesity Genes
Nicholas M. Morton, Yvonne B. Nelson, Zoi Michailidou, Emma M. Di Rollo, Lynne Ramage, Patrick W. F. Hadoke, Jonathan R. Seckl, Lutz Bunger, Simon Horvat, Christopher J. Kenyon, Donald R. Dunbar
PLoS One. 2011; 6(9): e23944. Published online 2011 Sep 7. doi: 10.1371/journal.pone.0023944
PMCID:
PMC3168488
AbstractArticlePDF–870K
15.
Hepatic Overexpression of a Constitutively Active Form of Liver Glycogen Synthase Improves Glucose Homeostasis
Susana Ros, Delia Zafra, Jordi Valles-Ortega, Mar García-Rocha, Stephen Forrow, Jorge Domínguez, Joaquim Calbó, Joan J. Guinovart
J Biol Chem. 2010 Nov 26; 285(48): 37170–37177. Published online 2010 Sep 14. doi: 10.1074/jbc.M110.157396
PMCID:
PMC2988323
AbstractArticlePDF–3.0M
16.
CLOCK Regulates Circadian Rhythms of Hepatic Glycogen Synthesis through Transcriptional Activation of Gys2
Ryosuke Doi, Katsutaka Oishi, Norio Ishida
J Biol Chem. 2010 Jul 16; 285(29): 22114–22121. Published online 2010 Apr 29. doi: 10.1074/jbc.M110.110361
PMCID:
PMC2903367
AbstractArticlePDF–1.7M
17.
Impaired Glucose Tolerance and Predisposition to the Fasted State in Liver Glycogen Synthase Knock-out Mice
Jose M. Irimia, Catalina M. Meyer, Caron L. Peper, Lanmin Zhai, Cheryl B. Bock, Stephen F. Previs, Owen P. McGuinness, Anna DePaoli-Roach, Peter J. Roach
J Biol Chem. 2010 Apr 23; 285(17): 12851–12861. Published online 2010 Feb 23. doi: 10.1074/jbc.M110.106534
PMCID:
PMC2857087
AbstractArticlePDF–2.3M
18.
The Imprinted Phlda2 Gene Regulates Extraembryonic Energy Stores
S. J. Tunster, B. Tycko, R. M. John
Mol Cell Biol. 2010 Jan; 30(1): 295–306. Published online 2009 Nov 2. doi: 10.1128/MCB.00662-09
PMCID:
PMC2798284
AbstractArticlePDF–4.9M
19.
Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors
S. Mandard, R. Stienstra, P. Escher, N. S. Tan, I. Kim, F. J. Gonzalez, W. Wahli, B. Desvergne, M. Müller, S. Kersten
Cell Mol Life Sci. 2007 May; 64(9): 1145. Published online 2007 Apr 16. doi: 10.1007/s00018-007-7006-1
PMCID:
PMC2771145
AbstractArticlePDF–1.0M
20.
In vivo role of the HNF4α AF-1 activation domain revealed by exon swapping
Nadège Briançon, Mary C Weiss
EMBO J. 2006 Mar 22; 25(6): 1253–1262. Published online 2006 Feb 23. doi: 10.1038/sj.emboj.7601021
PMCID:
PMC1422155
AbstractArticlePDF–593K

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