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Select item 110262871.

Role of transient receptor potential ankyrin 1 in idiopathic pulmonary fibrosis: modulation of M2 macrophage polarization

Yi Yang, Zhenyu Xiao, Weijie Yang, Yangyang Sun, Xin Sui, Xueyang Lin, Xinyi Yang, Zhenghao Bao, Ziqi Cui, Yingkai Ma, Weidong Li, Shengran Wang, Jun Yang, Yongan Wang, Yuan Luo

Cell Mol Life Sci. 2024 Dec; 81(1): 187. Published online 2024 Apr 18. doi: 10.1007/s00018-024-05219-x

PMCID:: PMC11026287

Abstract Article PDF–23M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108700283.

Discovery of PRDM16‐Mediated TRPA1 Induction as the Mechanism for Low Tubulo‐Interstitial Fibrosis in Diabetic Kidney Disease

Fang Xu, Hongwei Jiang, Xiaozhou Li, Jian Pan, Huiling Li, Luxiang Wang, Pan Zhang, Junxiang Chen, Shuangfa Qiu, Yuxin Xie, Yijian Li, Dongshan Zhang, Zheng Dong

Adv Sci (Weinh) 2024 Feb; 11(7): 2306704. Published online 2023 Dec 10. doi: 10.1002/advs.202306704

PMCID:: PMC10870028

Abstract Article PDF–21M

Select item 108551304.

The Lack of TRPA1 Ion Channel Does Not Affect the Chronic Stress-Induced Activation of the Locus Ceruleus

Milica Milicic, Balázs Gaszner, Gergely Berta, Erika Pintér, Viktória Kormos

Int J Mol Sci. 2024 Feb; 25(3): 1765. Published online 2024 Feb 1. doi: 10.3390/ijms25031765

PMCID:: PMC10855130

Abstract Article PDF–3.0M

Select item 107881645.

Canine, mouse, and human transient receptor potential ankyrin 1 (TRPA1) channels show different sensitivity to menthol or cold stimulation

Takuya YAMAGUCHI, Kunitoshi UCHIDA, Jun YAMAZAKI

J Vet Med Sci. 2023 Dec; 85(12): 1301–1309. Published online 2023 Oct 11. doi: 10.1292/jvms.23-0327

PMCID:: PMC10788164

Abstract Article PDF–2.7M

Select item 106986356.

A Novel Flp Reporter Mouse Shows That TRPA1 Expression Is Largely Limited to Sensory Neuron Subsets

Mayur J. Patil, Seol-Hee Kim, Parmvir K. Bahia, Sanjay S. Nair, Teresa S. Darcey, Jailene Fiallo, Xiao Xia Zhu, Robert D. Frisina, Stephen H. Hadley, Thomas E. Taylor-Clark

eNeuro. 2023 Dec; 10(12): ENEURO.0350-23.2023. Prepublished online 2023 Nov 21. Published online 2023 Dec 4. doi: 10.1523/ENEURO.0350-23.2023

PMCID:: PMC10698635

Abstract Article PDF–5.5M

Select item 105822647.

TRPA1-dependent and -independent activation by commonly used preservatives

Maximilian L. Mager, Cosmin I. Ciotu, Markus Gold-Binder, Stefan Heber, Michael J. M. Fischer

Front Pharmacol. 2023; 14: 1248558. Published online 2023 Oct 4. doi: 10.3389/fphar.2023.1248558

PMCID:: PMC10582264

Abstract Article PDF–2.0M

Select item 105571788.

TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage

Fei Deng, Heping Zhang, Wei Zhou, Shijie Ma, Yuwei Kang, Wei Yang, Liangbin Zhao, Wei Qin

J Transl Med. 2023; 21: 695. Published online 2023 Oct 5. doi: 10.1186/s12967-023-04351-9

PMCID:: PMC10557178

Abstract Article PDF–10M

Select item 105529419.

Lipopolysaccharide-Induced TRPA1 Upregulation in Trigeminal Neurons is Dependent on TLR4 and Vesicular Exocytosis

Benoit Michot, Sharon M. Casey, Caroline S. Lee, Ozge Erdogan, Himanish Basu, Isaac Chiu, Jennifer L. Gibbs

J Neurosci. 2023 Oct 4; 43(40): 6731–6744. doi: 10.1523/JNEUROSCI.0162-23.2023

PMCID:: PMC10552941

Abstract Article PDF–4.2M

Select item 1051424010.

MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel

Ping Lu, Yonghui Zhao, Zili Xie, Huan Zhou, Xinzhong Dong, Gregory F. Wu, Brian S. Kim, Jing Feng, Hongzhen Hu

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Apr 25; 42(4): 112283. Published online 2023 Mar 22. doi: 10.1016/j.celrep.2023.112283

PMCID:: PMC10514240

Abstract Article PDF–2.0M

Select item 1045452911.

The Contribution of TRPA1 to Corneal Thermosensitivity and Blink Regulation in Young and Aged Mice

Laura Frutos-Rincón, Carolina Luna, Fernando Aleixandre-Carrera, Enrique Velasco, Ariadna Diaz-Tahoces, Víctor Meseguer, Juana Gallar, M. Carmen Acosta

Int J Mol Sci. 2023 Aug; 24(16): 12620. Published online 2023 Aug 9. doi: 10.3390/ijms241612620

PMCID:: PMC10454529

Abstract Article PDF–2.1M

Select item 1043471412.

TRPA1 and TPRV1 Ion Channels Are Required for Contact Lens-Induced Corneal Parainflammation and Can Modulate Levels of Resident Corneal Immune Cells

Ananya Datta, Ji Hyun Lee, Orneika Flandrin, Hart Horneman, Justin Lee, Matteo M. E. Metruccio, Diana Bautista, David J. Evans, Suzanne M. J. Fleiszig

Invest Ophthalmol Vis Sci. 2023 Aug; 64(11): 21. Published online 2023 Aug 16. doi: 10.1167/iovs.64.11.21

PMCID:: PMC10434714

Abstract Article PDF–9.5M

Select item 1036158813.

The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production

Masashi Kakae, Hiroki Nakajima, Shota Tobori, Ayaka Kawashita, Jun Miyanohara, Misa Morishima, Kazuki Nagayasu, Takayuki Nakagawa, Eiji Shigetomi, Schuichi Koizumi, Yasuo Mori, Shuji Kaneko, Hisashi Shirakawa

Sci Adv. 2023 Jul; 9(29): eadh0102. Published online 2023 Jul 21. doi: 10.1126/sciadv.adh0102

PMCID:: PMC10361588

Abstract Article PDF–2.6M

Select item 1031377314.

TRPA1 activation in non-sensory supporting cells contributes to regulation of cochlear sensitivity after acoustic trauma

A. Catalina Vélez-Ortega, Ruben Stepanyan, Stephanie E. Edelmann, Sara Torres-Gallego, Channy Park, Desislava A. Marinkova, Joshua S. Nowacki, Ghanshyam P. Sinha, Gregory I. Frolenkov

Nat Commun. 2023; 14: 3871. Published online 2023 Jun 30. doi: 10.1038/s41467-023-39589-w

PMCID:: PMC10313773

Abstract Article PDF–9.3M

Select item 1025267015.

Neuropathic-like Nociception and Spinal Cord Neuroinflammation Are Dependent on the TRPA1 Channel in Multiple Sclerosis Models in Mice

Diéssica Padilha Dalenogare, Daniel Souza Monteiro de Araújo, Lorenzo Landini, Mustafa Titiz, Gaetano De Siena, Francesco De Logu, Pierangelo Geppetti, Romina Nassini, Gabriela Trevisan

Cells. 2023 Jun; 12(11): 1511. Published online 2023 May 30. doi: 10.3390/cells12111511

PMCID:: PMC10252670

Abstract Article PDF–3.2M

Select item 1023226216.

IQGAP1 promotes chronic pain by regulating the trafficking and sensitization of TRPA1 channels

Shakil Khan, Pabitra Hriday Patra, Hannah Somerfield, Hattaya Benya-Aphikul, Manoj Upadhya, Xuming Zhang

Brain. 2023 Jun; 146(6): 2595–2611. Published online 2022 Dec 7. doi: 10.1093/brain/awac462

PMCID:: PMC10232262

Abstract Article PDF–1.7M

Select item 1013132117.

Acetaldehyde via CGRP receptor and TRPA1 in Schwann cells mediates ethanol-evoked periorbital mechanical allodynia in mice: relevance for migraine

Lorenzo Landini, Daniel Souza Monteiro de Araujo, Martina Chieca, Gaetano De Siena, Elisa Bellantoni, Pierangelo Geppetti, Romina Nassini, Francesco De Logu

J Biomed Sci. 2023; 30: 28. Published online 2023 Apr 26. doi: 10.1186/s12929-023-00922-6

PMCID:: PMC10131321

Abstract Article PDF–4.1M

Select item 1008924618.

Endogenous Inflammatory Mediators Produced by Injury Activate TRPV1 and TRPA1 Nociceptors to Induce Sexually Dimorphic Cold Pain That Is Dependent on TRPM8 and GFRα3

Chenyu Yang, Shanni Yamaki, Tyler Jung, Brian Kim, Ryan Huyhn, David D. McKemy

J Neurosci. 2023 Apr 12; 43(15): 2803–2814. doi: 10.1523/JNEUROSCI.2303-22.2023

PMCID:: PMC10089246

Abstract Article PDF–2.4M

Select item 1007788819.

TMEM100, a regulator of TRPV1-TRPA1 interaction, contributes to temporomandibular disorder pain

Peng Wang, Qiaojuan Zhang, Fabiana C. Dias, Abbie Suttle, Xinzhong Dong, Yong Chen

Front Mol Neurosci. 2023; 16: 1160206. Published online 2023 Mar 23. doi: 10.3389/fnmol.2023.1160206

PMCID:: PMC10077888

Abstract Article PDF–3.3M

Select item 1001635520.

Acid-sensing ion channel 3 is required for agmatine-induced histamine-independent itch in mice

Guo-Kun Zhou, Wen-Jing Xu, Yi Lu, Yan Zhou, Chen-Zhang Feng, Jiang-Tao Zhang, Shi-Yu Sun, Ruo-Meng Wang, Tong Liu, Bin Wu

Front Mol Neurosci. 2023; 16: 1086285. Published online 2023 Mar 1. doi: 10.3389/fnmol.2023.1086285

PMCID:: PMC10016355

Abstract Article PDF–6.1M

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