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    Items: 1 to 20 of 42

    1.
    Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway
    Kevin Alicea-Torres, Emilio Sanseviero, Jun Gui, Jinyun Chen, Filippo Veglia, Qiujin Yu, Laxminarasimha Donthireddy, Andrew Kossenkov, Cindy Lin, Shuyu Fu, Charles Mulligan, Brian Nam, Gregory Masters, Fred Denstman, Joseph Bennett, Neil Hockstein, Agnieszka Rynda-Apple, Yulia Nefedova, Serge Y. Fuchs, Dmitry I. Gabrilovich
    Nat Commun. 2021; 12: 1717. Published online 2021 Mar 19. doi: 10.1038/s41467-021-22033-2
    PMCID:
    PMC7979850
    ArticlePDF–1.0M
    2.
    Interferon Receptor Trafficking and Signaling: Journey to the Cross Roads
    Natacha Zanin, Christine Viaris de Lesegno, Christophe Lamaze, Cedric M. Blouin
    Front Immunol. 2020; 11: 615603. Published online 2021 Jan 20. doi: 10.3389/fimmu.2020.615603
    PMCID:
    PMC7855707
    ArticlePDF–2.0M
    3.
    Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
    Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar, Evan Peter Williams, Lillian Zalduondo, Parimal Samir, Min Zheng, Balamurugan Sundaram, Balaji Banoth, R.K. Subbarao Malireddi, Patrick Schreiner, Geoffrey Neale, Peter Vogel, Richard Webby, Colleen Beth Jonsson, Thirumala-Devi Kanneganti
    Cell. 2021 Jan 7; 184(1): 149–168.e17. Published online 2020 Nov 19. doi: 10.1016/j.cell.2020.11.025
    PMCID:
    PMC7674074
    ArticlePDF–9.9M
    4.
    Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion
    David E. Place, Benoit Briard, Parimal Samir, Rajendra Karki, Anannya Bhattacharya, Clifford S. Guy, Jennifer L. Peters, Sharon Frase, Peter Vogel, Geoffrey Neale, Masahiro Yamamoto, Thirumala-Devi Kanneganti
    PLoS Pathog. 2020 Mar; 16(3): e1008364. Published online 2020 Mar 9. doi: 10.1371/journal.ppat.1008364
    PMCID:
    PMC7082077
    ArticlePDF–6.9M
    5.
    IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections
    Kelly M. Shepardson, Kyle Larson, Laura L. Johns, Kayla Stanek, Hanbyul Cho, Julia Wellham, Haley Henderson, Agnieszka Rynda-Apple
    Front Immunol. 2018; 9: 2589. Published online 2018 Nov 9. doi: 10.3389/fimmu.2018.02589
    PMCID:
    PMC6237881
    ArticlePDF–1.9M
    6.
    Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection
    Qifan Zhu, Si Ming Man, Rajendra Karki, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti
    Cell Rep. Author manuscript; available in PMC 2018 Oct 28.
    Published in final edited form as: Cell Rep. 2018 Mar 20; 22(12): 3168–3174. doi: 10.1016/j.celrep.2018.02.096
    PMCID:
    PMC6204211
    ArticlePDF–1.6M
    7.
    Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice
    Javier A. Carrero, Nicholas D. Benshoff, Kimberly Nalley, Emil R. Unanue
    Diabetes. 2018 Sep; 67(9): 1830–1835. Published online 2018 Jul 3. doi: 10.2337/db18-0331
    PMCID:
    PMC6110319
    ArticlePDF–1.6M
    8.
    IRF8 regulates transcription of Naips for NLRC4 inflammasome activation
    Rajendra Karki, Ein Lee, David Place, Parimal Samir, Jayadev Mavuluri, Bhesh Raj Sharma, Arjun Balakrishnan, R. K. Subbarao Malireddi, Rechel Geiger, Qifan Zhu, Geoffrey Neale, Thirumala-Devi Kanneganti
    Cell. Author manuscript; available in PMC 2019 May 3.
    Published in final edited form as: Cell. 2018 May 3; 173(4): 920–933.e13. Published online 2018 Mar 22. doi: 10.1016/j.cell.2018.02.055
    PMCID:
    PMC5935577
    ArticlePDF–2.0M
    9.
    Distinct regulatory mechanisms control proinflammatory cytokines IL-18 and IL-1β
    Qifan Zhu, Thirumala-Devi Kannegant
    J Immunol. Author manuscript; available in PMC 2018 Jun 1.
    Published in final edited form as: J Immunol. 2017 Jun 1; 198(11): 4210–4215. Published online 2017 May 3. doi: 10.4049/jimmunol.1700352
    PMCID:
    PMC5544497
    ArticlePDF–569K
    10.
    SYK licenses MyD88 to instigate IL-1α-mediated inflammatory disease
    Prajwal Gurung, Gaofeng Fan, John R. Lukens, Peter Vogel, Nicholas K Tonks, Thirumala-Devi Kanneganti
    Immunity. Author manuscript; available in PMC 2018 Apr 18.
    Published in final edited form as: Immunity. 2017 Apr 18; 46(4): 635–648. Published online 2017 Apr 11. doi: 10.1016/j.immuni.2017.03.014
    PMCID:
    PMC5501252
    ArticlePDF–1.1M
    11.
    The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity
    Yichuan Xiao, Qiang Zou, Xiaoping Xie, Ting Liu, Haiyan S. Li, Zuliang Jie, Jin Jin, Hongbo Hu, Ganiraju Manyam, Li Zhang, Xuhong Cheng, Hui Wang, Isabelle Marie, David E. Levy, Stephanie S. Watowich, Shao-Cong Sun
    J Exp Med. 2017 May 1; 214(5): 1493–1507. doi: 10.1084/jem.20161524
    PMCID:
    PMC5413337
    ArticlePDF–3.4M
    12.
    Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects
    Elena Bekerman, Gregory Neveu, Ana Shulla, Jennifer Brannan, Szu-Yuan Pu, Stanley Wang, Fei Xiao, Rina Barouch-Bentov, Russell R. Bakken, Roberto Mateo, Jennifer Govero, Claude M. Nagamine, Michael S. Diamond, Steven De Jonghe, Piet Herdewijn, John M. Dye, Glenn Randall, Shirit Einav
    J Clin Invest. 2017 Apr 3; 127(4): 1338–1352. Published online 2017 Feb 27. doi: 10.1172/JCI89857
    PMCID:
    PMC5373883
    ArticlePDF–1.6M
    13.
    A Mouse Model of Zika Virus Sexual Transmission and Vaginal Viral Replication
    William Weihao Tang, Matthew Perry Young, Anila Mamidi, Jose Angel Regla-Nava, Kenneth Kim, Sujan Shresta
    Cell Rep. Author manuscript; available in PMC 2017 Dec 20.
    Published in final edited form as: Cell Rep. 2016 Dec 20; 17(12): 3091–3098. doi: 10.1016/j.celrep.2016.11.070
    PMCID:
    PMC5193244
    ArticlePDF–1.0M
    14.
    ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
    Teneema Kuriakose, Si Ming Man, R.K. Subbarao Malireddi, Rajendra Karki, Sannula Kesavardhana, David E. Place, Geoffrey Neale, Peter Vogel, Thirumala-Devi Kanneganti
    Sci Immunol. Author manuscript; available in PMC 2016 Dec 1.
    Published in final edited form as: Sci Immunol. 2016 Aug 5; 1(2): aag2045. Published online 2016 Aug 12. doi: 10.1126/sciimmunol.aag2045
    PMCID:
    PMC5131924
    ArticlePDF–2.2M
    15.
    Interferon alpha inhibits spinal cord synaptic and nociceptive transmission via neuronal-glial interactions
    Chien-Cheng Liu, Yong-Jing Gao, Hao Luo, Temugin Berta, Zhen-Zhong Xu, Ru-Rong Ji, Ping-Heng Tan
    Sci Rep. 2016; 6: 34356. Published online 2016 Sep 27. doi: 10.1038/srep34356
    PMCID:
    PMC5037469
    ArticlePDF–2.2M
    16.
    B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
    Shaun W. Jackson, Holly M. Jacobs, Tanvi Arkatkar, Elizabeth M. Dam, Nicole E. Scharping, Nikita S. Kolhatkar, Baidong Hou, Jane H. Buckner, David J. Rawlings
    J Exp Med. 2016 May 2; 213(5): 733–750. doi: 10.1084/jem.20151724
    PMCID:
    PMC4854732
    ArticlePDF–3.5M
    17.
    Development of Th17-associated interstitial kidney inflammation in lupus-prone mice lacking the gene encoding Signal Transduction and Activator of Transcription-1 (STAT-1)
    Gloria Yiu, Tue Kruse Rasmussen, Bahareh Ajami, David J. Haddon, Alvina D. Chu, Stephanie Tangsombatvisit, Winston A. Haynes, Vivian Diep, Larry Steinman, James Faix, Paul J. Utz
    Arthritis Rheumatol. Author manuscript; available in PMC 2016 May 1.
    Published in final edited form as: Arthritis Rheumatol. 2016 May; 68(5): 1233–1244. doi: 10.1002/art.39535
    PMCID:
    PMC4848130
    ArticlePDF–3.1M
    18.
    Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses
    Barbara Kroczynska, Robert L. Rafidi, Beata Majchrzak-Kita, Ewa M. Kosciuczuk, Gavin T. Blyth, Jacek Jemielity, Zofia Warminska, Diana Saleiro, Swarna Mehrotra, Ahmet Dirim Arslan, Eleanor N. Fish, Leonidas C. Platanias
    J Biol Chem. 2016 Jan 29; 291(5): 2389–2396. Published online 2015 Dec 8. doi: 10.1074/jbc.M115.664995
    PMCID:
    PMC4732221
    ArticlePDF–1.0M
    19.
    TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
    Burcu Temizoz, Etsushi Kuroda, Keiichi Ohata, Nao Jounai, Koji Ozasa, Kouji Kobiyama, Taiki Aoshi, Ken J Ishii
    Eur J Immunol. 2015 Apr; 45(4): 1159–1169. Published online 2015 Feb 5. doi: 10.1002/eji.201445132
    PMCID:
    PMC4671267
    ArticlePDF–893K
    20.
    Hydroxypropyl-β-Cyclodextrin Spikes Local Inflammation That Induces Th2 Cell and T Follicular Helper Cell Responses to the Coadministered Antigen
    Motoyasu Onishi, Koji Ozasa, Kouji Kobiyama, Keiichi Ohata, Mitsutaka Kitano, Keiichi Taniguchi, Tomoyuki Homma, Masanori Kobayashi, Akihiko Sato, Yuko Katakai, Yasuhiro Yasutomi, Edward Wijaya, Yoshinobu Igarashi, Noriyuki Nakatsu, Wataru Ise, Takeshi Inoue, Hiroshi Yamada, Alexis Vandenbon, Daron M. Standley, Tomohiro Kurosaki, Cevayir Coban, Taiki Aoshi, Etsushi Kuroda, Ken J. Ishii
    J Immunol. 2015 Mar 15; 194(6): 2673–2682. Published online 2015 Feb 13. doi: 10.4049/jimmunol.1402027
    PMCID:
    PMC4470223
    ArticlePDF–1.5M

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