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Select item 105658761.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102431162.

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification

Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt

J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706

PMCID:: PMC10243116

Abstract Article PDF–13M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81080934.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 77254685.

Mus81-Eme1–dependent aberrant processing of DNA replication intermediates in mitosis impairs genome integrity

Nicolás Luis Calzetta, Marina Alejandra González Besteiro, Vanesa Gottifredi

Sci Adv. 2020 Dec; 6(50): eabc8257. Published online 2020 Dec 9. doi: 10.1126/sciadv.abc8257

PMCID:: PMC7725468

Abstract Article PDF–4.9M

Select item 69865636.

Pathway Analysis of Single-Nucleotide Polymorphisms Potentially Associated with Glioblastoma Multiforme Susceptibility Using Random Forests

Jeffrey S. Chang, Ru-Fang Yeh, John K. Wiencke, Joseph L. Wiemels, Ivan Smirnov, Alexander R. Pico, Tarik Tihan, Joe Patoka, Rei Miike, Jennette D. Sison, Terri Rice, Margaret R. Wrensch

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2020 Jan 28.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Jun; 17(6): 1368–1373. doi: 10.1158/1055-9965.EPI-07-2830

PMCID:: PMC6986563

Abstract Article PDF–327K

Select item 68212777.

SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair

Huimin Zhang, Zhen Chen, Yin Ye, Zu Ye, Dan Cao, Yun Xiong, Mrinal Srivastava, Xu Feng, Mengfan Tang, Chao Wang, John A Tainer, Junjie Chen

Nucleic Acids Res. 2019 Nov 4; 47(19): 10181–10201. Published online 2019 Sep 9. doi: 10.1093/nar/gkz769

PMCID:: PMC6821277

Abstract Article PDF–3.8M

Select item 67781378.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 64200979.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

Select item 616668210.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 600750911.

Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress

Anita Palma, Giusj Monia Pugliese, Ivana Murfuni, Veronica Marabitti, Eva Malacaria, Sara Rinalducci, Anna Minoprio, Massimo Sanchez, Filomena Mazzei, Lello Zolla, Annapaola Franchitto, Pietro Pichierri

Nucleic Acids Res. 2018 Jun 1; 46(10): 5109–5124. Published online 2018 Apr 18. doi: 10.1093/nar/gky280

PMCID:: PMC6007509

Abstract Article PDF–3.6M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 501610013.

SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr)

Xiaohong Zhou, Maria DeLucia, Jinwoo Ahn

J Biol Chem. 2016 Aug 12; 291(33): 16936–16947. Published online 2016 Jun 27. doi: 10.1074/jbc.M116.721183

PMCID:: PMC5016100

Abstract Article PDF–3.4M

Select item 474871214.

UHRF1 Contributes to DNA Damage Repair as a Lesion Recognition Factor and Nuclease Scaffold

Yanyan Tian, Manikandan Paramasivam, Gargi Ghosal, Ding Chen, Xi Shen, Yaling huang, Shamima Akhter, Randy Legerski, Junjie Chen, Michael M Seidman, Jun Qin, Lei Li

Cell Rep. Author manuscript; available in PMC 2016 Feb 10.

Published in final edited form as: Cell Rep. 2015 Mar 31; 10(12): 1957–1966. Published online 2015 Mar 26. doi: 10.1016/j.celrep.2015.03.038

PMCID:: PMC4748712

Abstract Article PDF–1.8M

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043