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Select item 109989081.

Gadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms

Peiwen Zhang, Na You, Yiyi Ding, Wenqi Zhu, Nan Wang, Yueqiao Xie, Wanling Huang, Qian Ren, Tiejun Qin, Rongfeng Fu, Lei Zhang, Zhijian Xiao, Tao Cheng, Xiaotong Ma

Nat Commun. 2024; 15: 2989. Published online 2024 Apr 6. doi: 10.1038/s41467-024-47297-2

PMCID:: PMC10998908

Abstract Article PDF–4.0M

Select item 105715122.

Identify GADD45G as a potential target of 4-methoxydalbergione in treatment of liver cancer: bioinformatics analysis and in vivo experiment

Li-Ping Zeng, Yu-Qi Qin, Xiao-Min Lu, Zhen-Bo Feng, Xian-Lei Fang

World J Surg Oncol. 2023; 21: 324. Published online 2023 Oct 13. doi: 10.1186/s12957-023-03214-3

PMCID:: PMC10571512

Abstract Article PDF–5.7M

Select item 100339373.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 89737734.

Circular RNA circCHFR downregulation protects against oxidized low-density lipoprotein-induced endothelial injury via regulation of microRNA-15b-5p/growth arrest and DNA damage inducible gamma

Yang Li, Bing Wang

Bioengineered. 2022; 13(2): 4481–4492. Published online 2022 Feb 9. doi: 10.1080/21655979.2022.2032967

PMCID:: PMC8973773

Abstract Article PDF–2.5M

Select item 85980655.

MAGEH1 interacts with GADD45G and induces renal tubular cell apoptosis

Gyu-Tae Shin, Ji Eun Park, Min-Jeong Lee

PLoS One. 2021; 16(11): e0260135. Published online 2021 Nov 17. doi: 10.1371/journal.pone.0260135

PMCID:: PMC8598065

Abstract Article PDF–3.8M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70592738.

Novel myocardial markers GADD45G and NDUFS5 identified by RNA-sequencing predicts left ventricular reverse remodeling in advanced non-ischemic heart failure: a retrospective cohort study

Togo Iwahana, Sho Okada, Masato Kanda, Motohiko Oshima, Atsushi Iwama, Goro Matsumiya, Yoshio Kobayashi

BMC Cardiovasc Disord. 2020; 20: 116. Published online 2020 Mar 5. doi: 10.1186/s12872-020-01396-2

PMCID:: PMC7059273

Abstract Article PDF–892K

Select item 67426469.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 643055710.

GADD45γ Activated Early in the Course of Herpes Simplex Virus 1 Infection Suppresses the Activation of a Network of Innate Immunity Genes

Mingmin She, Haifang Jiang, Xiaoxiang Chen, Xiaoqing Chen, Xianjie Liu, Xueyan Zhang, Bernard Roizman, Grace G. Zhou

J Virol. 2019 Apr 1; 93(7): e02201-18. Prepublished online 2019 Jan 30. Published online 2019 Mar 21. doi: 10.1128/JVI.02201-18

PMCID:: PMC6430557

Abstract Article PDF–1.2M

Select item 638626811.

Growth arrest and DNA damage 45γ is required for caspase-dependent renal tubular cell apoptosis

Gyu-Tae Shin, Hwa Joung Lee, Ji Eun Park

PLoS One. 2019; 14(2): e0212818. Published online 2019 Feb 22. doi: 10.1371/journal.pone.0212818

PMCID:: PMC6386268

Abstract Article PDF–3.4M

Select item 492468412.

GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

Rodrigo E. Tamura, Juliano D. Paccez, Kristal C. Duncan, Mirian G. Morale, Fernando M. Simabuco, Simon Dillon, Ricardo G. Correa, Xuesong Gu, Towia A. Libermann, Luiz F. Zerbini

Oncotarget. 2016 Mar 22; 7(12): 13865–13879. Published online 2016 Feb 12. doi: 10.18632/oncotarget.7355

PMCID:: PMC4924684

Abstract Article PDF–3.0M

Select item 487529313.

Crystal structure of human Gadd45 reveals an active dimer

Wenzheng Zhang, Sheng Fu, Xuefeng Liu, Xuelian Zhao, Wenchi Zhang, Wei Peng, Congying Wu, Yuanyuan Li, Xuemei Li, Mark Bartlam, Zong-Hao Zeng, Qimin Zhan, Zihe Rao

Protein Cell. 2011 Oct; 2(10): 814–826. Published online 2011 Nov 6. doi: 10.1007/s13238-011-1090-6

Correction in:: Protein Cell. 2012 Mar; 3(3): 239.

PMCID:: PMC4875293

Abstract Article PDF–2.9M

Select item 483136014.

Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering β‐catenin signalling and GADD45G expression

Lijuan Zhao, Shuman Li, Lin Gan, Chunhong Li, Zhu Qiu, Yixiao Feng, Jisheng Li, Lili Li, Chen Li, Weiyan Peng, Can Xu, Zhenyu Wang, Tianli Hui, Guosheng Ren, Qian Tao, Tingxiu Xiang

J Cell Mol Med. 2016 May; 20(5): 842–854. Published online 2016 Feb 4. doi: 10.1111/jcmm.12768

PMCID:: PMC4831360

Abstract Article PDF–1.2M

Select item 480532915.

Possible Role of GADD45γ Methylation in Diffuse Large B-Cell Lymphoma: Does It Affect the Progression and Tissue Involvement?

İkbal Cansu Barış, Vildan Caner, Nilay Şen Türk, İsmail Sarı, Sibel Hacıoğlu, Mehmet Hilmi Doğu, Ozan Çetin, Emre Tepeli, Özge Can, Gülseren Bağcı, Ali Keskin

Turk J Haematol. 2015 Dec; 32(4): 295–303. Published online 2015 Dec 3. doi: 10.4274/tjh.2014.0174

PMCID:: PMC4805329

Abstract Article PDF–278K

Select item 474179116.

SIP1 is a downstream effector of GADD45G in senescence induction and growth inhibition of liver tumor cells

Guiqin Xu, Li Zhang, Aihui Ma, Yu Qian, Qi Ding, Yun Liu, Boshi Wang, Zhaojuan Yang, Yongzhong Liu

Oncotarget. 2015 Oct 20; 6(32): 33636–33647. Published online 2015 Sep 10. doi: 10.18632/oncotarget.5602

PMCID:: PMC4741791

Abstract Article PDF–12M

Select item 469503717.

Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma

Da-Liang Ou, Song-Kun Shyue, Liang-In Lin, Zi-Rui Feng, Jun-Yang Liou, Hsiang-Hsuan Fan, Bin-Shyun Lee, Chiun Hsu, Ann-Lii Cheng

Oncotarget. 2015 Sep 29; 6(29): 27953–27965. Published online 2015 Jun 29. doi: 10.18632/oncotarget.4446

PMCID:: PMC4695037

Abstract Article PDF–6.1M

Select item 426658818.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 424053619.

MicroRNA-383 Regulates the Apoptosis of Tumor Cells through Targeting Gadd45g

Lei Zhao, Haihui Gu, Jianfeng Chang, Junyu Wu, Daliang Wang, Su Chen, Xiaomei Yang, Baohua Qian

PLoS One. 2014; 9(11): e110472. Published online 2014 Nov 21. doi: 10.1371/journal.pone.0110472

PMCID:: PMC4240536

Abstract Article PDF–1.4M

Select item 413659220.

GADD45γ regulates the thermogenic capacity of brown adipose tissue

Marin L. Gantner, Bethany C. Hazen, Juliana Conkright, Anastasia Kralli

Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32): 11870–11875. Published online 2014 Jul 28. doi: 10.1073/pnas.1406638111

PMCID:: PMC4136592

Abstract Article PDF–1.1M

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