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Items: 1 to 20 of 27

1.
Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin2 G protein–coupled receptor
Katie M. Babin, Jordan A. Karim, Peyton H. Gordon, James Lennon, Alex Dickson, Augen A. Pioszak
J Biol Chem. 2023 Jun; 299(6): 104785. Published online 2023 May 4. doi: 10.1016/j.jbc.2023.104785
PMCID:
PMC10248883
AbstractArticlePDF–4.6M
2.
CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2
Harsha Nagar, Seonhee Kim, Ikjun Lee, Su-Jeong Choi, Shuyu Piao, Byeong Hwa Jeon, Minho Shong, Cuk-Seong Kim
PLoS One. 2021; 16(8): e0256646. Published online 2021 Aug 26. doi: 10.1371/journal.pone.0256646
PMCID:
PMC8389428
AbstractArticlePDF–2.9M
3.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway
Yanhong Wang, Juanjuan Wang, Jia Yang, Jing Kang, Fuping Xue, Sijia Chang, He Ji, Haojing Zang, Xiaoshuang Zhou, Guiqin Wang, Weiping Fan, Xianyan Yan, Jinli Guo, Xiaojun Ren, Jihua Tian
Oxid Med Cell Longev. 2021; 2021: 8889408. Published online 2021 Aug 14. doi: 10.1155/2021/8889408
PMCID:
PMC8382522
AbstractArticlePDF–4.5M
4.
CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells
Ashley J. Clark, Niamh Mullooly, Dewi Safitri, Matthew Harris, Tessa de Vries, Antoinette MaassenVanDenBrink, David R. Poyner, Davide Gianni, Mark Wigglesworth, Graham Ladds
Commun Biol. 2021; 4: 776. Published online 2021 Jun 23. doi: 10.1038/s42003-021-02293-w
PMCID:
PMC8222276
AbstractArticlePDF–3.1M
5.
Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway
Xian-Qiang Ni, Ya-Rong Zhang, Li-Xin Jia, Wei-Wei Lu, Qing Zhu, Jin-Ling Ren, Yao Chen, Lin-Shuang Zhang, Xin Liu, Yan-Rong Yu, Mo-Zhi Jia, Zhong-Ping Ning, Jie Du, Chao-Shu Tang, Yong-Fen Qi
Aging (Albany NY) 2021 Feb 28; 13(4): 5164–5184. Published online 2021 Feb 1. doi: 10.18632/aging.202436
PMCID:
PMC7950288
AbstractArticlePDF–2.4M
6.
Intermedin facilitates hepatocellular carcinoma cell survival and invasion via ERK1/2-EGR1/DDIT3 signaling cascade
Fei Xiao, Hongyu Li, Zhongxue Feng, Luping Huang, Lingmiao Kong, Min Li, Denian Wang, Fei Liu, Zhijun Zhu, Yong’gang Wei, Wei Zhang
Sci Rep. 2021; 11: 488. Published online 2021 Jan 12. doi: 10.1038/s41598-020-80066-x
PMCID:
PMC7803743
AbstractArticlePDF–12M
7.
Altered expression of ADM and ADM2 by hypoxia regulates migration of trophoblast and HLA-G expression
Changdai Gu, Sohae Park, Jin Seok, Hee Yeon Jang, Yong Ju Bang, G I Jin Kim
Biol Reprod. 2021 Jan; 104(1): 159–169. Published online 2020 Sep 30. doi: 10.1093/biolre/ioaa178
PMCID:
PMC7786263
AbstractArticlePDF–1.1M
8.
Development of chimeric and bifunctional antagonists for CLR/RAMP receptors
Chia Lin Chang, Sheau Yu Teddy Hsu
PLoS One. 2019; 14(5): e0216996. Published online 2019 May 31. doi: 10.1371/journal.pone.0216996
PMCID:
PMC6544337
AbstractArticlePDF–2.8M
9.
Intermedin protects HUVECs from ischemia reperfusion injury via Wnt/β-catenin signaling pathway
Yanhong Wang, Zhijing Wu, Jihua Tian, Yang Mi, Xiaojun Ren, Jing Kang, Wan Zhang, Xiaoshuang Zhou, Guiqin Wang, Rongshan Li
Ren Fail. 2019; 41(1): 159–166. Published online 2019 Apr 1. doi: 10.1080/0886022X.2019.1587468
PMCID:
PMC6450471
AbstractArticlePDF–1.1M
10.
Structure–function analyses reveal a triple β-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design
Amanda M. Roehrkasse, Jason M. Booe, Sang-Min Lee, Margaret L. Warner, Augen A. Pioszak
J Biol Chem. 2018 Oct 12; 293(41): 15840–15854. Published online 2018 Aug 23. doi: 10.1074/jbc.RA118.005062
PMCID:
PMC6187615
AbstractArticlePDF–3.5M
11.
Intermedin protects against sepsis by concurrently re-establishing the endothelial barrier and alleviating inflammatory responses
Fei Xiao, Denian Wang, Lingmiao Kong, Min Li, Zhongxue Feng, Bingxing Shuai, Lijun Wang, Yong’gang Wei, Hongyu Li, Sisi Wu, Chun Tan, Huan Zhao, Xuejiao Hu, Jin Liu, Yan Kang, Xuelian Liao, Yan Zhou, Wei Zhang
Nat Commun. 2018; 9: 2644. Published online 2018 Jul 6. doi: 10.1038/s41467-018-05062-2
PMCID:
PMC6035189
AbstractArticlePDF–6.1M
12.
Adrenomedullin 2 Enhances Beiging in White Adipose Tissue Directly in an Adipocyte-autonomous Manner and Indirectly through Activation of M2 Macrophages
Ying Lv, Song-Yang Zhang, Xianyi Liang, Heng Zhang, Zhi Xu, Bo Liu, Ming-Jiang Xu, Changtao Jiang, Jin Shang, Xian Wang
J Biol Chem. 2016 Nov 4; 291(45): 23390–23402. Published online 2016 Sep 12. doi: 10.1074/jbc.M116.735563
PMCID:
PMC5095396
AbstractArticlePDF–2.9M
13.
Adrenomedullin 2 (ADM2) Regulates Mucin 1 at the Maternal-Fetal Interface in Human Pregnancy
Madhu Chauhan, Meena Balakrishnan, Rexanna Chan, Chandrasekhar Yallampalli
Biol Reprod. 2015 Dec; 93(6): 136. Published online 2015 Oct 28. doi: 10.1095/biolreprod.115.134296
PMCID:
PMC4712695
AbstractArticlePDF–1.4M
14.
PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion
Anna E. Dart, Gary M. Box, William Court, Madeline E. Gale, John P. Brown, Sarah E. Pinder, Suzanne A. Eccles, Claire M. Wells
J Cell Biol. 2015 Nov 23; 211(4): 863–879. doi: 10.1083/jcb.201501072
PMCID:
PMC4657161
AbstractArticlePDF–8.1M
15.
Intermedin/Adrenomedullin 2 Is Associated With Implantation and Placentation via Trophoblast Invasion in Human Pregnancy
Dara Havemann, Meena Balakrishnan, Mostafa Borahay, Regan Theiler, Kristofer Jennings, Janice Endsley, John Phelps, Gary D. V. Hankins, Chandra Yallampalli, Madhu Chauhan
J Clin Endocrinol Metab. 2013 Feb; 98(2): 695–703. Published online 2013 Jan 21. doi: 10.1210/jc.2012-2172
PMCID:
PMC3565110
AbstractArticle
16.
The pharmacology of Adrenomedullin 2/Intermedin
Yanguo Hong, Debbie L Hay, Remi Quirion, David R Poyner
Br J Pharmacol. 2012 May; 166(1): 110–120. doi: 10.1111/j.1476-5381.2011.01530.x
PMCID:
PMC3415642
AbstractArticlePDF–821K
17.
Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers
M Aslam, U Pfeil, D Gündüz, A Rafiq, W Kummer, HM Piper, T Noll
Br J Pharmacol. 2012 Jan; 165(1): 208–222. doi: 10.1111/j.1476-5381.2011.01540.x
PMCID:
PMC3252978
AbstractArticlePDF–4.2M
18.
Regulation of Oocyte and Cumulus Cell Interactions by Intermedin/Adrenomedullin 2
Chia Lin Chang, Hsin-Shih Wang, Yung-Kuei Soong, Shang Yu Huang, Shun Yuan Pai, Sheau Yu Teddy Hsu
J Biol Chem. 2011 Dec 16; 286(50): 43193–43203. Published online 2011 Oct 18. doi: 10.1074/jbc.M111.297358
PMCID:
PMC3234849
AbstractArticlePDF–2.1M
19.
Adrenomedullin 2/Intermedin Regulates HLA-G in Human Trophoblasts
Madhu Chauhan, Meena Balakrishnan, Uma Yallampalli, Janice Endsley, Gary D.V. Hankins, Regan Theiler, Chandra Yallampalli
Biol Reprod. 2011 Dec; 85(6): 1232–1239. Published online 2011 Aug 3. doi: 10.1095/biolreprod.110.086835
PMCID:
PMC3223254
AbstractArticlePDF–862K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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