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Items: 1 to 20 of 44

1.
A narrow T cell receptor repertoire instructs thymic differentiation of MHC class Ib–restricted CD8+ regulatory T cells
Hye-Jung Kim, Hidetoshi Nakagawa, John Y. Choi, Xuchun Che, Andrew Divris, Qingshi Liu, Andrew E. Wight, Hengcheng Zhang, Anis Saad, Zhabiz Solhjou, Christa Deban, Jamil R. Azzi, Harvey Cantor
J Clin Invest. 2024 Jan 2; 134(1): e170512. Published online 2024 Jan 2. doi: 10.1172/JCI170512
PMCID:
PMC10760956
AbstractArticlePDF–2.1M
2.
The promiscuous development of an unconventional Qa1b-restricted T cell population
Michael Manoharan Valerio, Kathya Arana, Jian Guan, Shiao Wei Chan, Xiaokun Yang, Nadia Kurd, Angus Lee, Nilabh Shastri, Laurent Coscoy, Ellen A. Robey
Front Immunol. 2023; 14: 1250316. Published online 2023 Oct 31. doi: 10.3389/fimmu.2023.1250316
PMCID:
PMC10644506
AbstractArticlePDF–2.8M
3.
Class Ib MHC–Mediated Immune Interactions Play a Critical Role in Maintaining Mucosal Homeostasis in the Mammalian Large Intestine
Suryasarathi Dasgupta, Igor Maricic, Jay Tang, Stephen Wandro, Kelly Weldon, Carolina S. Carpenter, Lars Eckmann, Jesus Rivera-Nieves, William Sandborn, Rob Knight, Peter Dorrestein, Austin D. Swafford, Vipin Kumar
Immunohorizons. Author manuscript; available in PMC 2023 Mar 20.
Published in final edited form as: Immunohorizons. 2021 Dec 15; 5(12): 953–971. Published online 2021 Dec 15. doi: 10.4049/immunohorizons.2100090
PMCID:
PMC10026853
AbstractArticlePDF–2.5M
4.
The nonclassical MHC class I Qa-1 expressed in layer 6 neurons regulates activity-dependent plasticity via microglial CD94/NKG2 in the cortex
Ioana A. Marin, Alan Y. Gutman-Wei, Kylie S. Chew, Aram J. Raissi, Maja Djurisic, Carla J. Shatz
Proc Natl Acad Sci U S A. 2022 Jun 7; 119(23): e2203965119. Published online 2022 Jun 1. doi: 10.1073/pnas.2203965119
PMCID:
PMC9191652
AbstractArticlePDF–4.6M
5.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
6.
Qa-1b modulates resistance to anti-PD-1 immune checkpoint blockade in tumors with defects in antigen processing
Xiao Zhang, Erich Sabio, Chirag Krishna, Xiaoxiao Ma, Jingming Wang, Hui Jiang, Jonathan J. Havel, Timothy A. Chan
Mol Cancer Res. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Mol Cancer Res. 2021 Jun; 19(6): 1076–1084. Published online 2021 Mar 5. doi: 10.1158/1541-7786.MCR-20-0652
PMCID:
PMC8178214
AbstractArticlePDF–1.7M
7.
Viral infection modulates Qa-1b in infected and bystander cells to properly direct NK cell killing
Maria Ferez, Cory J. Knudson, Avital Lev, Eric B. Wong, Pedro Alves-Peixoto, Lingjuan Tang, Colby Stotesbury, Luis J. Sigal
J Exp Med. 2021 May 3; 218(5): e20201782. Published online 2021 Mar 25. doi: 10.1084/jem.20201782
PMCID:
PMC8006856
AbstractArticlePDF–3.6M
8.
Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues
Paula Ruibal, Kees L. M. C. Franken, Krista E. van Meijgaarden, Joeri J. F. van Loon, Dirk van der Steen, Mirjam H. M. Heemskerk, Tom H. M. Ottenhoff, Simone A. Joosten
J Immunol. 2020 Nov 15; 205(10): 2861–2872. Published online 2020 Oct 5. doi: 10.4049/jimmunol.2000810
PMCID:
PMC7653511
AbstractArticlePDF–1.7M
9.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
10.
Coupling of terminal differentiation deficit with neurodegenerative pathology in Vps35-deficient pyramidal neurons
Fu-Lei Tang, Lu Zhao, Yang Zhao, Dong Sun, Xiao-Juan Zhu, Lin Mei, Wen-Cheng Xiong
Cell Death Differ. 2020 Jul; 27(7): 2099–2116. Published online 2020 Jan 6. doi: 10.1038/s41418-019-0487-2
PMCID:
PMC7308361
AbstractArticlePDF–7.3M
11.
Regulatory CD8 T cells that recognize Qa-1 expressed by CD4 T-helper cells inhibit rejection of heart allografts
John Y. Choi, Siawosh K. Eskandari, Songjie Cai, Ina Sulkaj, Jean Pierre Assaker, Hazim Allos, Juliano AlHaddad, Saif A. Muhsin, Eman Alhussain, Amr Mansouri, Melissa Y. Yeung, Marc A. J. Seelen, Hye-Jung Kim, Harvey Cantor, Jamil R. Azzi
Proc Natl Acad Sci U S A. 2020 Mar 17; 117(11): 6042–6046. Published online 2020 Feb 28. doi: 10.1073/pnas.1918950117
PMCID:
PMC7084119
AbstractArticlePDF–1.2M
12.
The murine CD94/NKG2 ligand, Qa-1b, is a high-affinity, functional ligand for the CD8αα homodimer
Katharine Jennifer Goodall, Angela Nguyen, Craig McKenzie, Sidonia Barbara Guiomar Eckle, Lucy Catherine Sullivan, Daniel Mark Andrews
J Biol Chem. 2020 Mar 6; 295(10): 3239–3246. Published online 2020 Jan 28. doi: 10.1074/jbc.RA119.010509
PMCID:
PMC7062157
AbstractArticlePDF–798K
13.
Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection
Courtney K. Anderson, Emma C. Reilly, Angus Y. Lee, Laurent Brossay
Cell Rep. Author manuscript; available in PMC 2019 Apr 18.
Published in final edited form as: Cell Rep. 2019 Apr 9; 27(2): 537–548.e5. doi: 10.1016/j.celrep.2019.03.059
PMCID:
PMC6472915
AbstractArticlePDF–1.9M
14.
NKG2A blockade potentiates CD8 T-cell immunity induced by cancer vaccines
Nadine van Montfoort, Linda Borst, Michael J. Korrer, Marjolein Sluijter, Koen A. Marijt, Saskia J. Santegoets, Vanessa J. van Ham, Ilina Ehsan, Pornpimol Charoentong, Pascale André, Nicolai Wagtmann, Marij J.P. Welters, Young J. Kim, Sytse J. Piersma, Sjoerd H. van der Burg, Thorbald van Hall
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1744–1755.e15. Published online 2018 Nov 29. doi: 10.1016/j.cell.2018.10.028
PMCID:
PMC6354585
AbstractArticlePDF–1.1M
15.
Non-classical immunity controls microbiota impact on skin immunity and tissue repair
Jonathan L. Linehan, Oliver J. Harrison, Seong-Ji Han, Allyson L. Byrd, Ivan Vujkovic-Cvijin, Alejandro V. Villarino, Shurjo K. Sen, Jahangheer Shaik, Margery Smelkinson, Samira Tamoutounour, Nicholas Collins, Nicolas Bouladoux, Amiran Dzutsev, Stephan P. Rosshart, Jesse H. Arbuckle, Chyung-Ru Wang, Thomas M. Kristie, Barbara Rehermann, Giorgio Trinchieri, Jason M. Brenchley, John J. O’Shea, Yasmine Belkaid
Cell. Author manuscript; available in PMC 2019 Feb 8.
Published in final edited form as: Cell. 2018 Feb 8; 172(4): 784–796.e18. Published online 2018 Jan 18. doi: 10.1016/j.cell.2017.12.033
PMCID:
PMC6034182
AbstractArticlePDF–1.8M
16.
Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance
Blair T. Stocks, Christopher S. Wilson, Andrew F. Marshall, Lauren A. Brewer, Daniel J. Moore
Sci Rep. 2017; 7: 11181. Published online 2017 Sep 11. doi: 10.1038/s41598-017-11780-2
PMCID:
PMC5593978
AbstractArticlePDF–1.7M
17.
Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells
Istéfani L. da Silva, Lucía Montero-Montero, Ester Martín-Villar, Jorge Martin-Pérez, Bruno Sainz, Jaime Renart, Renata Toscano Simões, Émerson Soares Veloso, Cláudia Salviano Teixeira, Mônica C. de Oliveira, Enio Ferreira, Miguel Quintanilla
Sci Rep. 2017; 7: 6276. Published online 2017 Jul 24. doi: 10.1038/s41598-017-06528-x
PMCID:
PMC5524840
AbstractArticlePDF–2.0M
18.
MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection
Yao Bian, Shaobin Shang, Sarah Siddiqui, Jie Zhao, Simone A. Joosten, Tom H. M. Ottenhoff, Harvey Cantor, Chyung-Ru Wang
PLoS Pathog. 2017 May; 13(5): e1006384. Published online 2017 May 5. doi: 10.1371/journal.ppat.1006384
PMCID:
PMC5435364
AbstractArticlePDF–7.7M
19.
Nonclassical MHC Ib-restricted CD8+ T Cells Recognize Mycobacterium tuberculosis-Derived Protein Antigens and Contribute to Protection Against Infection
Shaobin Shang, Sarah Siddiqui, Yao Bian, Jie Zhao, Chyung-Ru Wang
PLoS Pathog. 2016 Jun; 12(6): e1005688. Published online 2016 Jun 7. doi: 10.1371/journal.ppat.1005688
PMCID:
PMC4896622
AbstractArticlePDF–1.2M
20.
Expression of the mouse MHC class Ib H2-T11 gene product, a paralog of H2-T23 (Qa-1) with shared peptide-binding specificity
Lili Chen, Eduardo Reyes-Vargas, Hu Dai, Hernando Escobar, Brant Rudd, Jared Fairbanks, Alexander Ho, Mathew F. Cusick, Attila Kumánovics, Julio Delgado, Xiao He, Peter E. Jensen
J Immunol. Author manuscript; available in PMC 2015 Aug 1.
Published in final edited form as: J Immunol. 2014 Aug 1; 193(3): 1427–1439. Published online 2014 Jun 23. doi: 10.4049/jimmunol.1302048
PMCID:
PMC4211609
AbstractArticlePDF–1.2M

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