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Select item 108666871.

A MAP1B–cortactin–Tks5 axis regulates TNBC invasion and tumorigenesis

Hiroki Inoue, Taku Kanda, Gakuto Hayashi, Ryota Munenaga, Masayuki Yoshida, Kana Hasegawa, Takuya Miyagawa, Yukiya Kurumada, Jumpei Hasegawa, Tomoyuki Wada, Motoi Horiuchi, Yasuhiro Yoshimatsu, Fumiko Itoh, Yuki Maemoto, Kohei Arasaki, Yuichi Wakana, Tetsuro Watabe, Hiromichi Matsushita, Hironori Harada, Mitsuo Tagaya

J Cell Biol. 2024 Mar 4; 223(3): e202303102. Published online 2024 Feb 14. doi: 10.1083/jcb.202303102

PMCID:: PMC10866687

Abstract Article PDF–8.5M

Select item 100729062.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 95699553.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 94754534.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 85850106.

Tks5 Regulates Synaptic Podosome Formation and Stabilization of the Postsynaptic Machinery at the Neuromuscular Junction

Marcin Pęziński, Kamila Maliszewska-Olejniczak, Patrycja Daszczuk, Paula Mazurek, Paweł Niewiadomski, Maria Jolanta Rędowicz

Int J Mol Sci. 2021 Nov; 22(21): 12051. Published online 2021 Nov 7. doi: 10.3390/ijms222112051

PMCID:: PMC8585010

Abstract Article PDF–1.9M

Select item 82770617.

The clinicopathologic significance of Tks5 expression of peritoneal mesothelial cells in gastric cancer patients

Atsushi Sugimoto, Tomohisa Okuno, Gen Tsujio, Tomohiro Sera, Yurie Yamamoto, Koji Maruo, Shuhei Kushiyama, Sadaaki Nishimura, Kenji Kuroda, Shingo Togano, Yuichiro Miki, Mami Yoshii, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Masaichi Ohira, Masakazu Yashiro

PLoS One. 2021; 16(7): e0253702. Published online 2021 Jul 13. doi: 10.1371/journal.pone.0253702

PMCID:: PMC8277061

Abstract Article PDF–823K

Select item 82547598.

HectD1 Controls Hematopoietic Stem Cell Regeneration by Coordinating Ribosome Assembly and Protein Synthesis

Kaosheng Lv, Chujie Gong, Charles Antony, Xu Han, Jian-Gang Ren, Ryan Donaghy, Ying Cheng, Simone Pellegrino, Alan J. Warren, Vikram R. Paralkar, Wei Tong

Cell Stem Cell. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Cell Stem Cell. 2021 Jul 1; 28(7): 1275–1290.e9. Published online 2021 Mar 11. doi: 10.1016/j.stem.2021.02.008

PMCID:: PMC8254759

Abstract Article PDF–2.8M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 796946910.

Serine-threonine kinase TAO3-mediated trafficking of endosomes containing the invadopodia scaffold TKS5α promotes cancer invasion and tumor growth

Shinji Iizuka, Manuela Quintavalle, Jose C. Navarro, Kyle P. Gribbin, Robert J. Ardecky, Matthew M. Abelman, Chen-Ting Ma, Eduard Sergienko, Fu-Yue Zeng, Ian Pass, George V. Thomas, Shannon K. McWeeney, Christian A. Hassig, Anthony B. Pinkerton, Sara A. Courtneidge

Cancer Res. Author manuscript; available in PMC 2021 Sep 15.

Published in final edited form as: Cancer Res. 2021 Mar 15; 81(6): 1472–1485. Published online 2021 Jan 7. doi: 10.1158/0008-5472.CAN-20-2383

PMCID:: PMC7969469

Abstract Article PDF–3.1M

Select item 748010811.

Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia

Anna Zagryazhskaya-Masson, Pedro Monteiro, Anne-Sophie Macé, Alessia Castagnino, Robin Ferrari, Elvira Infante, Aléria Duperray-Susini, Florent Dingli, Arpad Lanyi, Damarys Loew, Elisabeth Génot, Philippe Chavrier

J Cell Biol. 2020 Sep 7; 219(9): e201910132. Published online 2020 Jul 16. doi: 10.1083/jcb.201910132

PMCID:: PMC7480108

Abstract Article PDF–6.7M

Select item 730149912.

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease

Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu

Transl Neurodegener. 2020; 9: 26. Published online 2020 Jun 18. doi: 10.1186/s40035-020-00206-1

PMCID:: PMC7301499

Abstract Article PDF–14M

Select item 699197813.

Tks5 SH3 domains exhibit differential effects on invadopodia development

Christina Daly, Brewer Logan, Joseph Breeyear, Kelley Whitaker, Maryam Ahmed, Darren F. Seals

PLoS One. 2020; 15(1): e0227855. Published online 2020 Jan 30. doi: 10.1371/journal.pone.0227855

PMCID:: PMC6991978

Abstract Article PDF–5.9M

Select item 694759714.

Non-Syndromic Cleft Lip with or without Cleft Palate: Genome-Wide Association Study in Europeans Identifies a Suggestive Risk Locus at 16p12.1 and Supports SH3PXD2A as a Clefting Susceptibility Gene

Iris ALM van Rooij, Kerstin U Ludwig, Julia Welzenbach, Nina Ishorst, Michelle Thonissen, Tessel E Galesloot, Edwin Ongkosuwito, Stefaan J Bergé, Khalid Aldhorae, Augusto Rojas-Martinez, Lambertus ALM Kiemeney, Joris Robert Vermeesch, Han Brunner, Nel Roeleveld, Koen Devriendt, Titiaan Dormaar, Greet Hens, Michael Knapp, Carine Carels, Elisabeth Mangold

Genes (Basel) 2019 Dec; 10(12): 1023. Published online 2019 Dec 7. doi: 10.3390/genes10121023

PMCID:: PMC6947597

Abstract Article PDF–1.5M

Select item 636846415.

TKS5-positive invadopodia-like structures in human tumor surgical specimens

Yu-Chuan Chen, Matthew Baik, Joshua T. Byers, Kathryn T. Chen, Samuel W. French, Begoña Díaz

Exp Mol Pathol. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Exp Mol Pathol. 2019 Feb; 106: 17–26. Published online 2018 Nov 12. doi: 10.1016/j.yexmp.2018.11.005

PMCID:: PMC6368464

Abstract Article PDF–1.0M

Select item 582692616.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 567858117.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 556849518.

Metabolic control of the scaffold protein TKS5 in tissue-invasive, pro-inflammatory T cells

Yi Shen, Zhenke Wen, Yinyin Li, Eric L. Matteson, Jison Hong, Jörg J. Goronzy, Cornelia M. Weyand

Nat Immunol. Author manuscript; available in PMC 2018 Jan 24.

Published in final edited form as: Nat Immunol. 2017 Sep; 18(9): 1025–1034. Published online 2017 Jul 24. doi: 10.1038/ni.3808

PMCID:: PMC5568495

Abstract Article PDF–1.3M

Select item 553161119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549522520.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

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