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Select item 111788421.

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics

Ken Hashimoto, Momoko Ohira, Aya Kodama, Misaki Kimoto, Mariko Inoue, Shigenobu Toné, Yuu Usui, Akira Hanashima, Takato Goto, Yuhei Ogura, Yoshihiro Ujihara, Satoshi Mohri

Sci Rep. 2024; 14: 13727. Published online 2024 Jun 14. doi: 10.1038/s41598-024-64608-1

PMCID:: PMC11178842

Abstract Article PDF–5.4M

Select item 111139002.

Ca_V1.2 and Ca_V1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum

Guang Yang, Yue Shi, Jia Yu, Yuxin Li, Lina Yu, Andrea Welling, Franz Hofmann, Jörg Striessnig, Lisa Juntti-Berggren, Per-Olof Berggren, Shao-Nian Yang

Cell Mol Life Sci. 2015 Mar; 72(6): 1197–1207. Published online 2014 Oct 8. doi: 10.1007/s00018-014-1737-6

PMCID:: PMC11113900

Abstract Article PDF–2.0M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107620684.

Selective blockade of Ca_v1.2 (α1C) versus Ca_v1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine

Pietro Mesirca, Jean Chemin, Christian Barrère, Eleonora Torre, Laura Gallot, Arnaud Monteil, Isabelle Bidaud, Sylvie Diochot, Michel Lazdunski, Tuck Wah Soong, Stéphanie Barrère-Lemaire, Matteo E. Mangoni, Joël Nargeot

Nat Commun. 2024; 15: 54. Published online 2024 Jan 2. doi: 10.1038/s41467-023-43502-w

PMCID:: PMC10762068

Abstract Article PDF–2.2M

Select item 105168845.

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction

Michael J. Davis, Jorge A. Castorena-Gonzalez, Scott D. Zawieja

Sci Rep. 2023; 13: 15862. Published online 2023 Sep 22. doi: 10.1038/s41598-023-42877-6

PMCID:: PMC10516884

Abstract Article PDF–1.7M

Select item 102971936.

Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis

Peilei Lu, Danyu Zhang, Fan Ding, Jialu Ma, Yang K. Xiang, Meimi Zhao

Cells. 2023 Jun; 12(12): 1667. Published online 2023 Jun 19. doi: 10.3390/cells12121667

PMCID:: PMC10297193

Abstract Article PDF–3.4M

Select item 102541187.

Increased Ca²⁺ signaling through Ca_V1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties

Haiyin Li, Antonion Korcari, David Ciufo, Christopher L. Mendias, Scott A. Rodeo, Mark R. Buckley, Alayna E. Loiselle, Geoffrey S. Pitt, Chike Cao

FASEB J. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: FASEB J. 2023 Jul; 37(7): e23007. doi: 10.1096/fj.202300607R

PMCID:: PMC10254118

Abstract Article PDF–3.3M

Select item 100231618.

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart

Valeria Taliani, Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Tiziana Santini, Silvia Galfrè, Leonardo Schirone, Davide Mariani, Giacomo Frati, Valentina Valenti, Sebastiano Sciarretta, Emerald Perlas, Carmine Nicoletti, Antonio Musarò, Monica Ballarino

eLife. 2023; 12: e81360. Published online 2023 Mar 6. doi: 10.7554/eLife.81360

PMCID:: PMC10023161

Abstract Article PDF–4.8M

Select item 99449429.

Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac Ca_V1.2 calcium channel

Liam Hovey, Xiaoyun Guo, Yi Chen, Qinghang Liu, William A. Catterall

Front Physiol. 2023; 14: 1049611. Published online 2023 Feb 8. doi: 10.3389/fphys.2023.1049611

PMCID:: PMC9944942

Abstract Article PDF–1.7M

Select item 990929910.

Mettl3 deficiency leads to the upregulation of Cav1.2 and increases arrhythmia susceptibility in mice: Mettl3 regulates L-type Ca currents of cardiomyocytes

Ling Shi, Xuexin Jin, Zheng Li, Rui Gong, Yang Guo, Jiudong Ma, Yang Zhang, Benzhi Cai, Baofeng Yang, Dongmei Gong, Zhenwei Pan

Acta Biochim Biophys Sin (Shanghai) 2022 Feb; 54(2): 199–208. Published online 2022 Jan 24. doi: 10.3724/abbs.2021025

PMCID:: PMC9909299

Abstract Article PDF–5.3M

Select item 987828511.

A vascular smooth muscle-specific integrin-α8 Cre mouse for lymphatic contraction studies that allows male-female comparisons and avoids visceral myopathy

Michael J. Davis, Hae Jin Kim, Min Li, Scott D. Zawieja

Front Physiol. 2022; 13: 1060146. Published online 2023 Jan 12. doi: 10.3389/fphys.2022.1060146

PMCID:: PMC9878285

Abstract Article PDF–1.5M

Select item 978034012.

Neuronal deletion of Ca_V1.2 is associated with sex-specific behavioral phenotypes in mice

Annette J. Klomp, Ashley Plumb, Jacqueline B. Mehr, Deniz A. Madencioglu, Hsiang Wen, Aislinn J. Williams

Sci Rep. 2022; 12: 22152. Published online 2022 Dec 22. doi: 10.1038/s41598-022-26504-4

PMCID:: PMC9780340

Abstract Article PDF–1.2M

Select item 964482513.

The Ca_V1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca²⁺ channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome

Jennifer L. Sanderson, Ronald K. Freund, Anna M. Castano, Timothy A. Benke, Mark L. Dell’Acqua

Neuropharmacology. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Neuropharmacology. 2022 Dec 1; 220: 109271. Published online 2022 Sep 24. doi: 10.1016/j.neuropharm.2022.109271

PMCID:: PMC9644825

Abstract Article PDF–1.8M

Select item 917707414.

Ca_v1.3 calcium channels are full-range linear amplifiers of firing frequencies in lateral DA SN neurons

Josef Shin, Lora Kovacheva, Dominique Thomas, Strahinja Stojanovic, Christopher J. Knowlton, Johanna Mankel, Johannes Boehm, Navid Farassat, Carlos Paladini, Jörg Striessnig, Carmen C. Canavier, Gerd Geisslinger, Jochen Roeper

Sci Adv. 2022 Jun; 8(23): eabm4560. Published online 2022 Jun 8. doi: 10.1126/sciadv.abm4560

PMCID:: PMC9177074

Abstract Article PDF–2.9M

Select item 916979815.

A molecular complex of Ca_v1.2/CaMKK2/CaMK1a in caveolae is responsible for vascular remodeling via excitation–transcription coupling

Yoshiaki Suzuki, Takumi Ozawa, Tomo Kurata, Nanami Nakajima, Gerald W. Zamponi, Wayne R. Giles, Yuji Imaizumi, Hisao Yamamura

Proc Natl Acad Sci U S A. 2022 Apr 19; 119(16): e2117435119. Published online 2022 Apr 11. doi: 10.1073/pnas.2117435119

PMCID:: PMC9169798

Abstract Article PDF–2.8M

Select item 899796716.

L-Type Ca_v1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells

Julien Louradour, Olivier Bortolotti, Eleonora Torre, Isabelle Bidaud, Ned Lamb, Anne Fernandez, Jean-Yves Le Guennec, Matteo E. Mangoni, Pietro Mesirca

Cells. 2022 Apr; 11(7): 1114. Published online 2022 Mar 25. doi: 10.3390/cells11071114

PMCID:: PMC8997967

Abstract Article PDF–4.1M

Select item 898313217.

Increased Ca²⁺ influx through Ca_V1.2 drives aortic valve calcification

Maiko Matsui, Rihab Bouchareb, Mara Storto, Yasin Hussain, Andrew Gregg, Steven O. Marx, Geoffrey S. Pitt

JCI Insight. 2022 Mar 8; 7(5): e155569. Published online 2022 Mar 8. doi: 10.1172/jci.insight.155569

PMCID:: PMC8983132

Abstract Article PDF–15M

Select item 880577018.

L-Type Calcium Channels Contribute to Ethanol-Induced Aberrant Tangential Migration of Primordial Cortical GABAergic Interneurons in the Embryonic Medial Prefrontal Cortex

Stephanie M. Lee, Pamela W. L. Yeh, Hermes H. Yeh

eNeuro. 2022 Jan-Feb; 9(1): ENEURO.0359-21.2021. Prepublished online 2021 Dec 20. Published online 2022 Jan 28. doi: 10.1523/ENEURO.0359-21.2021

PMCID:: PMC8805770

Abstract Article PDF–2.5M

Select item 874867119.

Enhanced long-term potentiation and impaired learning in mice lacking alternative exon 33 of Ca_V1.2 calcium channel

Sheeja Navakkode, Jing Zhai, Yuk Peng Wong, Guang Li, Tuck Wah Soong

Transl Psychiatry. 2022; 12: 1. Published online 2022 Jan 10. doi: 10.1038/s41398-021-01683-2

PMCID:: PMC8748671

Abstract Article PDF–1.2M

Select item 863544620.

Heart neurons use clock genes to control myocyte proliferation

Emmanouil Tampakakis, Harshi Gangrade, Stephanie Glavaris, Myo Htet, Sean Murphy, Brian Leei Lin, Ting Liu, Amir Saberi, Matthew Miyamoto, William Kowalski, Yoh-Suke Mukouyama, Gabsang Lee, Liliana Minichiello, Chulan Kwon

Sci Adv. 2021 Dec; 7(49): eabh4181. Published online 2021 Dec 1. doi: 10.1126/sciadv.abh4181

PMCID:: PMC8635446

Abstract Article PDF–6.2M

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