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Select item 100275621.

Hepatocyte estrogen sulfotransferase inhibition protects female mice from concanavalin A–induced T cell–mediated hepatitis independent of estrogens

Jingyuan Wang, Ziteng Zhang, Jibin Guan, Hung-Chun Tung, Jiaxuan Xie, Haozhe Huang, Yuang Chen, Meishu Xu, Songrong Ren, Song Li, Min Zhang, Da Yang, Wen Xie

J Biol Chem. 2023 Mar; 299(3): 103026. Published online 2023 Feb 15. doi: 10.1016/j.jbc.2023.103026

PMCID:: PMC10027562

Abstract Article PDF–6.2M

Select item 82735162.

Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells

Pauline Sararols, Isabelle Stévant, Yasmine Neirijnck, Diane Rebourcet, Annalucia Darbey, Michael K. Curley, Françoise Kühne, Emmanouil Dermitzakis, Lee B. Smith, Serge Nef

Front Cell Dev Biol. 2021; 9: 695546. Published online 2021 Jun 28. doi: 10.3389/fcell.2021.695546

PMCID:: PMC8273516

Abstract Article PDF–8.1M

Select item 73510103.

Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice

Anne C. Silva Barbosa, Dong Zhou, Yang Xie, You-Jin Choi, Hung-Chun Tung, Xinyun Chen, Meishu Xu, Robert B. Gibbs, Samuel M. Poloyac, Silvia Liu, Yanping Yu, Jianhua Luo, Youhua Liu, Wen Xie

J Am Soc Nephrol. 2020 Jul; 31(7): 1496–1508. Published online 2020 May 18. doi: 10.1681/ASN.2019080767

PMCID:: PMC7351010

Abstract Article

Select item 70812544.

Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver

MyeongJin Yi, Muluneh Fashe, Shingo Arakawa, Rick Moore, Tatsuya Sueyoshi, Masahiko Negishi

Sci Rep. 2020; 10: 5001. Published online 2020 Mar 19. doi: 10.1038/s41598-020-61767-9

PMCID:: PMC7081254

Abstract Article PDF–2.4M

Select item 69704545.

Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung Injury

Yang Xie, Anne Caroline S Barbosa, Meishu Xu, Patrick J Oberly, Songrong Ren, Robert B Gibbs, Samuel M Poloyac, Wen-Chao Song, Jie Fan, Wen Xie

Endocrinology. 2020 Jan; 161(1): bqz031. Published online 2019 Dec 14. doi: 10.1210/endocr/bqz031

PMCID:: PMC6970454

Abstract Article

Select item 66349716.

Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice

Jorge López-Tello, Vicente Pérez-García, Jaspreet Khaira, Laura C Kusinski, Wendy N Cooper, Adam Andreani, Imogen Grant, Edurne Fernández de Liger, Brian YH Lam, Myriam Hemberger, Ionel Sandovici, Miguel Constancia, Amanda N Sferruzzi-Perri

eLife. 2019; 8: e45282. Published online 2019 Jun 26. doi: 10.7554/eLife.45282

PMCID:: PMC6634971

Abstract Article PDF–4.5M

Select item 65512077.

Glucocorticoids Antagonize Estrogens by Glucocorticoid Receptor–Mediated Activation of Estrogen Sulfotransferase

Haibiao Gong, Michael J. Jarzynka, Timothy J. Cole, Jung Hoon Lee, Taira Wada, Bin Zhang, Jie Gao, Wen-Chao Song, Donald B. DeFranco, Shi-Yuan Cheng, Wen Xie

Cancer Res. Author manuscript; available in PMC 2019 Jun 5.

Published in final edited form as: Cancer Res. 2008 Sep 15; 68(18): 7386–7393. doi: 10.1158/0008-5472.CAN-08-1545

PMCID:: PMC6551207

Abstract Article PDF–1.5M

Select item 61021448.

Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor–mediated suppression of the estrogen sulfotransferase SULT1E1

Xijun Liu, Ruyi Xue, Caiting Yang, Jianxin Gu, She Chen, Si Zhang

J Biol Chem. 2018 Aug 17; 293(33): 12759–12769. Published online 2018 Jun 21. doi: 10.1074/jbc.RA118.001789

PMCID:: PMC6102144

Abstract Article PDF–2.5M

Select item 56958329.

Sex- and Tissue-Specific Role of Estrogen Sulfotransferase in Energy Homeostasis and Insulin Sensitivity

Wojciech G. Garbacz, Mengxi Jiang, Meishu Xu, Jun Yamauchi, H. Henry Dong, Wen Xie

Endocrinology. 2017 Nov 1; 158(11): 4093–4104. Published online 2017 Sep 5. doi: 10.1210/en.2017-00571

PMCID:: PMC5695832

Abstract Article

Select item 555228010.

Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1

Noriko Matsushita, Mohamed T. Hassanein, Marcos Martinez-Clemente, Raul Lazaro, Samuel W. French, Wen Xie, Keane Lai, Michael Karin, Hidekazu Tsukamoto

PLoS One. 2017; 12(8): e0181052. Published online 2017 Aug 10. doi: 10.1371/journal.pone.0181052

PMCID:: PMC5552280

Abstract Article PDF–6.7M

Select item 471190411.

Steroidogenic Factor 1 Differentially Regulates Fetal and Adult Leydig Cell Development in Male Mice

Tatiana Karpova, Kumarasamy Ravichandiran, Lovella Insisienmay, Daren Rice, Valentine Agbor, Leslie L. Heckert

Biol Reprod. 2015 Oct; 93(4): 83. Published online 2015 Aug 12. doi: 10.1095/biolreprod.115.131193

PMCID:: PMC4711904

Abstract Article PDF–2.8M

Select item 466661312.

Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome

Luke Isbel, Rahul Srivastava, Harald Oey, Alex Spurling, Lucia Daxinger, Hamsa Puthalakath, Emma Whitelaw

PLoS Genet. 2015 Dec; 11(12): e1005693. Published online 2015 Dec 1. doi: 10.1371/journal.pgen.1005693

PMCID:: PMC4666613

Abstract Article PDF–5.9M

Select item 453295113.

Estrogen sulfotransferase ablation sensitizes mice to sepsis

Xiaojuan Chai, Yan Guo, Mengxi Jiang, Bingfang Hu, Zhigang Li, Jie Fan, Meihong Deng, Timothy R. Billiar, Heidi Kucera, Nilesh W. Gaikwad, Meishu Xu, Peipei Lu, Jiong Yan, Haiyan Fu, Youhua Liu, Lushan Yu, Min Huang, Su Zeng, Wen Xie

Nat Commun. Author manuscript; available in PMC 2016 Feb 10.

Published in final edited form as: Nat Commun. 2015; 6: 7979. Published online 2015 Aug 10. doi: 10.1038/ncomms8979

PMCID:: PMC4532951

Abstract Article PDF–2.3M

Select item 450554014.

Estrogen Sulfotransferase Is an Oxidative Stress-responsive Gene That Gender-specifically Affects Liver Ischemia/Reperfusion Injury

Yan Guo, Bingfang Hu, Hai Huang, Allan Tsung, Nilesh W. Gaikwad, Meishu Xu, Mengxi Jiang, Songrong Ren, Jie Fan, Timothy R. Billiar, Min Huang, Wen Xie

J Biol Chem. 2015 Jun 5; 290(23): 14754–14764. Published online 2015 Apr 28. doi: 10.1074/jbc.M115.642124

PMCID:: PMC4505540

Abstract Article PDF–2.8M

Select item 438637615.

Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation

Lianjun Zhang, Min Chen, Qing Wen, Yaqiong Li, Yaqing Wang, Yanbo Wang, Yan Qin, Xiuhong Cui, Lin Yang, Vicki Huff, Fei Gao

Proc Natl Acad Sci U S A. 2015 Mar 31; 112(13): 4003–4008. Published online 2015 Mar 16. doi: 10.1073/pnas.1422371112

PMCID:: PMC4386376

Abstract Article PDF–1.8M

Select item 428321816.

Increased gene copy number of the vesicle SNARE VAMP7 disrupts human male urogenital development through altered estrogen action

Mounia Tannour-Louet, Shuo Han, Jean-Francois Louet, Bin Zhang, Karina Romero, Josephine Addai, Aysegul Sahin, Sau Wai Cheung, Dolores J Lamb

Nat Med. Author manuscript; available in PMC 2015 Jan 5.

Published in final edited form as: Nat Med. 2014 Jul; 20(7): 715–724. Published online 2014 Jun 1. doi: 10.1038/nm.3580

PMCID:: PMC4283218

Abstract Article PDF–3.1M

Select item 385542117.

Regulation of hepatic sulfotransferase (SULT) 1E1 expression and effects on estrogenic activity in cystic fibrosis (CF)

Charles N. Falany, Dongning He, Li Li, Josie L. Falany, Teresa W. Wilborn, Thomas A. Kocarek, Melissa Runge-Morris

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2013 Dec 7.

Published in final edited form as: J Steroid Biochem Mol Biol. 2009 Mar; 114(0): 10.1016/j.jsbmb.2009.02.009. Published online 2009 Mar 3. doi: 10.1016/j.jsbmb.2009.02.009

PMCID:: PMC3855421

Abstract Article PDF–1.9M

Select item 357241018.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163