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Select item 115395941.

NOD2 protects against allergic lung inflammation in obese female mice

Rodrigo Rodrigues e-Lacerda, Nicole G. Barra, Han Fang, Gabriel Forato Anhê, Jonathan D. Schertzer

iScience. 2024 Nov 15; 27(11): 111130. Published online 2024 Oct 11. doi: 10.1016/j.isci.2024.111130

PMCID:: PMC11539594

Abstract Article PDF–7.5M

Select item 108585172.

NOD1 deficiency ameliorates the progression of diabetic retinopathy by modulating bone marrow–retina crosstalk

Jingwen Qiu, Jing Wu, Wenwen Chen, Yu Ruan, Jingning Mao, Shue Li, Xuan Tang, Lei Zhao, Shengbing Li, Ke Li, Dongfang Liu, Yaqian Duan

Stem Cell Res Ther. 2024; 15: 38. Published online 2024 Feb 9. doi: 10.1186/s13287-024-03654-y

PMCID:: PMC10858517

Abstract Article PDF–10M

Select item 102932523.

NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice

L. S. Tran, L. Ying, K. D’Costa, G. Wray-McCann, G. Kerr, L. Le, C. C. Allison, J. Ferrand, H. Chaudhry, J. Emery, A. De Paoli, N. Colon, S. Creed, M. Kaparakis-Liaskos, J. Como, J. K. Dowling, P. A. Johanesen, T. A. Kufer, J. S. Pedersen, A. Mansell, D. J. Philpott, K. D. Elgass, H. E. Abud, U. Nachbur, B. A. Croker, S. L. Masters, R. L. Ferrero

Nat Commun. 2023; 14: 3804. Published online 2023 Jun 26. doi: 10.1038/s41467-023-39487-1

PMCID:: PMC10293252

Abstract Article PDF–1.7M

Select item 101950324.

Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity

Ravi Bharadwaj, Christina F. Lusi, Siavash Mashayekh, Abhinit Nagar, Okuda, Amanda Monahan, Donggi Paik, Anubhab Nandy, Madison V. Anonick, William E. Goldman, Thirumala-Devi Kanneganti, Megan H. Orzalli, Catherine Leimkuhler Grimes, Prabhani U. Atukorale, Neal Silverman

Immunity. Author manuscript; available in PMC 2024 May 9.

Published in final edited form as: Immunity. 2023 May 9; 56(5): 998–1012.e8. Published online 2023 Apr 27. doi: 10.1016/j.immuni.2023.04.001

PMCID:: PMC10195032

Abstract Article PDF–2.5M

Select item 92565805.

High-fat diet activates splenic NOD1 and enhances neutrophil recruitment and neutrophil extracellular traps release in the spleen of ApoE-deficient mice

Victoria Fernández-García, Silvia González-Ramos, José Avendaño-Ortiz, Paloma Martín-Sanz, Diego Gómez-Coronado, Carmen Delgado, Antonio Castrillo, Lisardo Boscá

Cell Mol Life Sci. 2022 Aug; 79(8): 396. Published online 2022 Jul 5. doi: 10.1007/s00018-022-04415-x

PMCID:: PMC9256580

Abstract Article PDF–1.8M

Select item 86168666.

CTRP-3 Regulates NOD1-mediated Inflammation and NOD1 Expression in Adipocytes and Adipose Tissue

Andreas Schmid, Andreas Schäffler, Thomas Karrasch

Inflammation. 2021; 44(6): 2260–2269. Published online 2021 Jun 24. doi: 10.1007/s10753-021-01497-w

PMCID:: PMC8616866

Abstract Article PDF–510K

Select item 84534457.

Nucleotide-Oligomerizing Domain-1 Activation Exaggerates Cigarette Smoke-Induced Chronic Obstructive Pulmonary-Like Disease in Mice

Guangchao Han, Min Li, Junfeng Du, Yang Chen, Chen Xu

Int J Chron Obstruct Pulmon Dis. 2021; 16: 2605–2615. Published online 2021 Sep 16. doi: 10.2147/COPD.S323616

PMCID:: PMC8453445

Abstract Article PDF–6.3M

Select item 83333438.

Intestinal microbiota modulates adrenomedullary response through Nod1 sensing in chromaffin cells

Chen Xiang, Peihua Chen, Qin Zhang, Yinghui Li, Ying Pan, Wenchun Xie, Jianyuan Sun, Zhihua Liu

iScience. 2021 Aug 20; 24(8): 102849. Published online 2021 Jul 10. doi: 10.1016/j.isci.2021.102849

PMCID:: PMC8333343

Abstract Article PDF–6.9M

Select item 79696479.

NOD1 Agonist Protects Against Lipopolysaccharide and D-Galactosamine-Induced Fatal Hepatitis Through the Upregulation of A20 Expression in Hepatocytes

Fang Jia, Fuxue Deng, Pan Xu, Shiying Li, Xuefu Wang, Peng Hu, Hong Ren, Shiwen Tong, Wenwei Yin

Front Immunol. 2021; 12: 603192. Published online 2021 Mar 4. doi: 10.3389/fimmu.2021.603192

PMCID:: PMC7969647

Abstract Article PDF–7.8M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 793457111.

Gut Microbiota Modulate CD8 T Cell Responses to Influence Colitis-Associated Tumorigenesis

Amy I. Yu, Lili Zhao, Kathryn A. Eaton, Sharon Ho, Jiachen Chen, Sara Poe, James Becker, Allison Gonzalez, Delaney McKinstry, Muneer Hasso, Jonny Mendoza-Castrejon, Joel Whitfield, Charles Koumpouras, Patrick D. Schloss, Eric C. Martens, Grace Y. Chen

Cell Rep. Author manuscript; available in PMC 2021 Mar 5.

Published in final edited form as: Cell Rep. 2020 Apr 7; 31(1): 107471. doi: 10.1016/j.celrep.2020.03.035

PMCID:: PMC7934571

Abstract Article PDF–3.2M

Select item 770824612.

NOD1/RIP2 signalling enhances the microglia-driven inflammatory response and undergoes crosstalk with inflammatory cytokines to exacerbate brain damage following intracerebral haemorrhage in mice

Miao Wang, Xinchun Ye, Jinxia Hu, Qiuchen Zhao, Bingchen Lv, Weijing Ma, Weiwei Wang, Hanhan Yin, Qi Hao, Chao Zhou, Tao Zhang, Weifeng Wu, Yan Wang, Mingyue Zhou, Cong-hui Zhang, Guiyun Cui

J Neuroinflammation. 2020; 17: 364. Published online 2020 Dec 1. doi: 10.1186/s12974-020-02015-9

PMCID:: PMC7708246

Abstract Article PDF–2.6M

Select item 770056713.

Genetic Deletion of NOD1 Prevents Cardiac Ca²⁺ Mishandling Induced by Experimental Chronic Kidney Disease

Marta Gil-Fernández, José Alberto Navarro-García, Almudena Val-Blasco, Laura González-Lafuente, José Carlos Martínez, Angélica Rueda, Maria Tamayo, José Luis Morgado, Carlos Zaragoza, Luis Miguel Ruilope, Carmen Delgado, Gema Ruiz-Hurtado, María Fernández-Velasco

Int J Mol Sci. 2020 Nov; 21(22): 8868. Published online 2020 Nov 23. doi: 10.3390/ijms21228868

PMCID:: PMC7700567

Abstract Article PDF–3.3M

Select item 756468914.

Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis

Silvia González-Ramos, Victoria Fernández-García, Miriam Recalde, Cristina Rodríguez, José Martínez-González, Vicente Andrés, Paloma Martín-Sanz, Lisardo Boscá

Cells. 2020 Sep; 9(9): 2067. Published online 2020 Sep 10. doi: 10.3390/cells9092067

PMCID:: PMC7564689

Abstract Article PDF–3.8M

Select item 737807815.

NOD1 deficiency promotes an imbalance of thyroid hormones and microbiota homeostasis in mice fed high fat diet

Silvia González-Ramos, Marta Paz-García, Victoria Fernández-García, Kevin J. Portune, Emilio F. Acosta-Medina, Yolanda Sanz, Antonio Castrillo, Paloma Martín-Sanz, Maria Jesus Obregon, Lisardo Boscá

Sci Rep. 2020; 10: 12317. Published online 2020 Jul 23. doi: 10.1038/s41598-020-69295-2

PMCID:: PMC7378078

Abstract Article PDF–7.1M

Select item 731668116.

Deficiency of Nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 reduces atherosclerosis

Ann-Kathrin Vlacil, Jutta Schuett, Volker Ruppert, Muhidien Soufi, Raghav Oberoi, Kinan Shahin, Christian Wächter, Thomas Tschernig, Yu Lei, Fan Liu, Uwe J. F. Tietge, Bernhard Schieffer, Harald Schuett, Karsten Grote

Basic Res Cardiol. 2020; 115(4): 47. Published online 2020 Jun 25. doi: 10.1007/s00395-020-0806-2

PMCID:: PMC7316681

Abstract Article PDF–988K

Select item 731495317.

Characterizing the BCG Induced Macrophage and Neutrophil Mechanisms for Defense Against Mycobacterium tuberculosis

Thomas E. Bickett, Jennifer McLean, Elizabeth Creissen, Linda Izzo, Cassidy Hagan, Antonio J. Izzo, Fabiola Silva Angulo, Angelo A. Izzo

Front Immunol. 2020; 11: 1202. Published online 2020 Jun 18. doi: 10.3389/fimmu.2020.01202

PMCID:: PMC7314953

Abstract Article PDF–1.5M

Select item 726788418.

NOD1/NOD2 and RIP2 Regulate Endoplasmic Reticulum Stress-Induced Inflammation during Chlamydia Infection

Oanh H. Pham, Bokyung Lee, Jasmine Labuda, A. Marijke Keestra-Gounder, Mariana X. Byndloss, Renée M. Tsolis, Stephen J. McSorley

mBio. 2020 May-Jun; 11(3): e00979-20. Published online 2020 Jun 2. doi: 10.1128/mBio.00979-20

PMCID:: PMC7267884

Abstract Article PDF–436K

Select item 723328719.

MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1

Nina Schmolka, Pedro H. Papotto, Paula Vargas Romero, Tiago Amado, Francisco J. Enguita, Ana Amorim, Ana F. Rodrigues, Katrina E. Gordon, Ana S. Coroadinha, Mark Boldin, Karine Serre, Amy H. Buck, Anita Q. Gomes, Bruno Silva-Santos

Sci Immunol. Author manuscript; available in PMC 2020 May 18.

Published in final edited form as: Sci Immunol. 2018 May 4; 3(23): eaao1392. doi: 10.1126/sciimmunol.aao1392

PMCID:: PMC7233287

Abstract Article PDF–2.1M

Select item 719244320.

Identification of microRNAs involved in NOD-dependent induction of pro-inflammatory genes in pulmonary endothelial cells

Ann-Kathrin Vlacil, Evelyn Vollmeister, Wilhelm Bertrams, Florian Schoesser, Raghav Oberoi, Jutta Schuett, Harald Schuett, Sonja Huehn, Katrin Bedenbender, Bernd T. Schmeck, Bernhard Schieffer, Karsten Grote

PLoS One. 2020; 15(4): e0228764. Published online 2020 Apr 30. doi: 10.1371/journal.pone.0228764

PMCID:: PMC7192443

Abstract Article PDF–1.7M

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