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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 99382162.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 96038603.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95745154.

A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert

J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484

PMCID:: PMC9574515

Abstract Article PDF–1.8M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 90156996.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 86436367.

Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis

Huawei Wang, Xiajing Shan, Mengtian Ren, Mengdi Shang, Chuanzheng Zhou

Nucleic Acids Res. 2021 Dec 2; 49(21): 12306–12319. Published online 2021 Nov 19. doi: 10.1093/nar/gkab1121

PMCID:: PMC8643636

Abstract Article PDF–4.6M

Select item 81398268.

Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction

Xingyu Zhang, Li Zou, Lanxia Meng, Min Xiong, Lina Pan, Guiqin Chen, Yongfa Zheng, Jing Xiong, Zhihao Wang, Duc M Duong, Zhaohui Zhang, Xuebing Cao, Tao Wang, Li Tang, Keqiang Ye, Zhentao Zhang

eLife. 2021; 10: e65301. Published online 2021 May 21. doi: 10.7554/eLife.65301

PMCID:: PMC8139826

Abstract Article PDF–8.4M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 741599110.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 725247711.

BRAG2a Mediates mGluR-Dependent AMPA Receptor Internalization at Excitatory Postsynapses through the Interaction with PSD-95 and Endophilin 3

Masahiro Fukaya, Takeyuki Sugawara, Yoshinobu Hara, Makoto Itakura, Masahiko Watanabe, Hiroyuki Sakagami

J Neurosci. 2020 May 27; 40(22): 4277–4296. doi: 10.1523/JNEUROSCI.1645-19.2020

PMCID:: PMC7252477

Abstract Article PDF–7.1M

Select item 704168812.

Clathrin’s adaptor interaction sites are repurposed to stabilize microtubules during mitosis

Arnaud Rondelet, Yu-Chih Lin, Divya Singh, Arthur T. Porfetye, Harish C. Thakur, Andreas Hecker, Pia Brinkert, Nadine Schmidt, Shweta Bendre, Franziska Müller, Lisa Mazul, Per O. Widlund, Tanja Bange, Michael Hiller, Ingrid R. Vetter, Alexander W. Bird

J Cell Biol. 2020 Feb 3; 219(2): e201907083. Published online 2020 Jan 13. doi: 10.1083/jcb.201907083

PMCID:: PMC7041688

Abstract Article PDF–4.2M

Select item 699392513.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 682337814.

Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension

Matteo Biancospino, Gwen R. Buel, Carlos A. Niño, Elena Maspero, Rossella Scotto di Perrotolo, Andrea Raimondi, Lisa Redlingshöfer, Janine Weber, Frances M. Brodsky, Kylie J. Walters, Simona Polo

Nat Commun. 2019; 10: 4974. Published online 2019 Oct 31. doi: 10.1038/s41467-019-12855-6

PMCID:: PMC6823378

Abstract Article PDF–2.7M

Select item 670346415.

Synaptotagmin 1 Is Necessary for the Ca²⁺ Dependence of Clathrin-Mediated Endocytosis

Li-Hua Yao, Yan Rao, Kelly Varga, Chun-Yang Wang, Peng Xiao, Manfred Lindau, Liang-Wei Gong

J Neurosci. 2012 Mar 14; 32(11): 3778–3785. doi: 10.1523/JNEUROSCI.3540-11.2012

PMCID:: PMC6703464

Abstract Article PDF–1.1M

Select item 668173616.

Cardiomyocyte orientation modulated by the Numb family proteins–N-cadherin axis is essential for ventricular wall morphogenesis

Lianjie Miao, Jingjing Li, Jian Li, Yangyang Lu, David Shieh, Joseph E. Mazurkiewicz, Margarida Barroso, John J. Schwarz, Hong-Bo Xin, Harold A. Singer, Peter A. Vincent, Weimin Zhong, Glenn L. Radice, Leo Q. Wan, Zhen-Chuan Fan, Guoying Huang, Mingfu Wu

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15560–15569. Published online 2019 Jul 12. doi: 10.1073/pnas.1904684116

PMCID:: PMC6681736

Abstract Article PDF–3.6M

Select item 665555117.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 663303618.

LRRK2 Controls Synaptic Vesicle Storage and Mobilization within the Recycling Pool

Giovanni Piccoli, Steven B. Condliffe, Matthias Bauer, Florian Giesert, Karsten Boldt, Silvia De Astis, Andrea Meixner, Hakan Sarioglu, Daniela M. Vogt-Weisenhorn, Wolfgang Wurst, Christian Johannes Gloeckner, Michela Matteoli, Carlo Sala, Marius Ueffing

J Neurosci. 2011 Feb 9; 31(6): 2225–2237. doi: 10.1523/JNEUROSCI.3730-10.2011

PMCID:: PMC6633036

Abstract Article PDF–2.5M

Select item 661859919.

A Local, Periactive Zone Endocytic Machinery at Photoreceptor Synapses in Close Vicinity to Synaptic Ribbons

Silke Wahl, Rashmi Katiyar, Frank Schmitz

J Neurosci. 2013 Jun 19; 33(25): 10278–10300. doi: 10.1523/JNEUROSCI.5048-12.2013

PMCID:: PMC6618599

Abstract Article PDF–9.6M

Select item 658968920.

Clathrin plaques and associated actin anchor intermediate filaments in skeletal muscle

Agathe Franck, Jeanne Lainé, Gilles Moulay, Eline Lemerle, Michaël Trichet, Christel Gentil, Sofia Benkhelifa-Ziyyat, Emmanuelle Lacène, Mai Thao Bui, Guy Brochier, Pascale Guicheney, Norma Romero, Marc Bitoun, Stéphane Vassilopoulos

Mol Biol Cell. 2019 Mar 1; 30(5): 579–590. doi: 10.1091/mbc.E18-11-0718

PMCID:: PMC6589689

Abstract Article PDF–5.4M

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