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Select item 107900861.

Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation

Ebru Ermis, Titli Nargis, Kierstin Webster, Sarah A. Tersey, Ryan M. Anderson, Raghavendra G. Mirmira

J Biol Chem. 2024 Jan; 300(1): 105561. Published online 2023 Dec 12. doi: 10.1016/j.jbc.2023.105561

PMCID:: PMC10790086

Abstract Article PDF–3.0M

Select item 99458432.

Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

Erwan Pernet, Sarah Sun, Nicole Sarden, Saideep Gona, Angela Nguyen, Nargis Khan, Martin Mawhinney, Kim A. Tran, Julia Chronopoulos, Dnyandeo Amberkar, Mina Sadeghi, Alexandre Grant, Shradha Wali, Renaud Prevel, Jun Ding, James G. Martin, Ajitha Thanabalasuriar, Bryan G. Yipp, Luis B. Barreiro, Maziar Divangahi

Nature. 2023; 614(7948): 530–538. Published online 2023 Jan 4. doi: 10.1038/s41586-022-05660-7

PMCID:: PMC9945843

Abstract Article PDF–44M

Select item 87183673.

Contributory Role of BLT2 in the Production of Proinflammatory Cytokines in Cecal Ligation and Puncture-Induced Sepsis

Donghwan Park, MyungJa Ro, A-Jin Lee, Dong-Wook Kwak, Yunro Chung, Jae-Hong Kim

Mol Cells. 2021 Dec 31; 44(12): 893–899. Published online 2021 Dec 10. doi: 10.14348/molcells.2021.0159

PMCID:: PMC8718367

Abstract Article PDF–3.2M

Select item 85692144.

Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation

Jae-Hyun Jang, Donghwan Park, Guen-soo Park, Dong-Wook Kwak, JaeIn Park, Dae-Yeul Yu, Hye Jin You, Jae-Hong Kim

Exp Mol Med. 2021 Oct; 53(10): 1559–1568. Published online 2021 Oct 11. doi: 10.1038/s12276-021-00682-z

PMCID:: PMC8569214

Abstract Article PDF–4.1M

Select item 80166595.

Leukotriene B₄ receptors contribute to house dust mite-induced eosinophilic airway inflammation via T_H2 cytokine production

Donghwan Park, Dong-Wook Kwak, Jae-Hong Kim

BMB Rep. 2021 Mar 31; 54(3): 182–187. Published online 2021 Mar 31. doi: 10.5483/BMBRep.2021.54.3.247

PMCID:: PMC8016659

Abstract Article PDF–7.5M

Select item 62372156.

Leukotriene B₄ promotes neovascularization and macrophage recruitment in murine wet-type AMD models

Fumiyuki Sasaki, Tomoaki Koga, Mai Ohba, Kazuko Saeki, Toshiaki Okuno, Keijiro Ishikawa, Takahito Nakama, Shintaro Nakao, Shigeo Yoshida, Tatsuro Ishibashi, Hamid Ahmadieh, Mozhgan Rezaei Kanavi, Ali Hafezi-Moghadam, Josef M. Penninger, Koh-Hei Sonoda, Takehiko Yokomizo

JCI Insight. 2018 Sep 20; 3(18): e96902. Published online 2018 Sep 20. doi: 10.1172/jci.insight.96902

PMCID:: PMC6237215

Abstract Article PDF–9.4M

Select item 56433017.

Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B₄ receptor 2

Satoshi Iwamoto, Tomoaki Koga, Mai Ohba, Toshiaki Okuno, Masato Koike, Akira Murakami, Akira Matsuda, Takehiko Yokomizo

Sci Rep. 2017; 7: 13267. Published online 2017 Oct 16. doi: 10.1038/s41598-017-13122-8

PMCID:: PMC5643301

Abstract Article PDF–7.6M

Select item 54960338.

Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling

Ann V. Hertzel, Hongliang Xu, Michael Downey, Nicholas Kvalheim, David A. Bernlohr

J Lipid Res. 2017 Jul; 58(7): 1354–1361. Published online 2017 May 25. doi: 10.1194/jlr.M074542

PMCID:: PMC5496033

Abstract Article PDF–897K

Select item 53917459.

The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons

Sebastian Zinn, Marco Sisignano, Katharina Kern, Sandra Pierre, Sorin Tunaru, Holger Jordan, Jing Suo, Elsa-Marie Treutlein, Carlo Angioni, Nerea Ferreiros, Andreas Leffler, Natasja DeBruin, Stefan Offermanns, Gerd Geisslinger, Klaus Scholich

J Biol Chem. 2017 Apr 14; 292(15): 6123–6134. Published online 2017 Feb 27. doi: 10.1074/jbc.M116.769125

PMCID:: PMC5391745

Abstract Article PDF–1.6M

Select item 533557910.

Macrophage LTB₄ drives efficient phagocytosis of Borrelia burgdorferi via BLT1 or BLT2

Yan Zhang, Rachel M. Olson, Charles R. Brown

J Lipid Res. 2017 Mar; 58(3): 494–503. Published online 2017 Feb 27. doi: 10.1194/jlr.M068882

PMCID:: PMC5335579

Abstract Article PDF–989K

Select item 406530711.

Mast cell maturation is driven via a group III phospholipase A₂-prostaglandin D₂–DP1 receptor paracrine axis

Yoshitaka Taketomi, Noriko Ueno, Takumi Kojima, Hiroyasu Sato, Remi Murase, Kei Yamamoto, Satoshi Tanaka, Mariko Sakanaka, Masanori Nakamura, Yasumasa Nishito, Momoko Kawana, Naotomo Kambe, Kazutaka Ikeda, Ryo Taguchi, Satoshi Nakamizo, Kenji Kabashima, Michael H. Gelb, Makoto Arita, Takehiko Yokomizo, Motonao Nakamura, Kikuko Watanabe, Hiroyuki Hirai, Masataka Nakamura, Yoshimichi Okayama, Chisei Ra, Kosuke Aritake, Yoshihiro Urade, Kazushi Morimoto, Yukihiko Sugimoto, Takao Shimizu, Shuh Narumiya, Shuntaro Hara, Makoto Murakami

Nat Immunol. Author manuscript; available in PMC 2014 Jun 21.

Published in final edited form as: Nat Immunol. 2013 Jun; 14(6): 554–563. Published online 2013 Apr 28. doi: 10.1038/ni.2586

PMCID:: PMC4065307

Abstract Article PDF–1.0M

Select item 404264312.

12-hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor

Min Liu, Kazuko Saeki, Takehiko Matsunobu, Toshiaki Okuno, Tomoaki Koga, Yukihiko Sugimoto, Chieko Yokoyama, Satoshi Nakamizo, Kenji Kabashima, Shuh Narumiya, Takao Shimizu, Takehiko Yokomizo

J Exp Med. 2014 Jun 2; 211(6): 1063–1078. doi: 10.1084/jem.20132063

PMCID:: PMC4042643

Abstract Article PDF–3.4M

Select item 334014213.

Leukotriene B₄ Receptor-2 Promotes Invasiveness and Metastasis of Ovarian Cancer Cells through Signal Transducer and Activator of Transcription 3 (STAT3)-dependent Up-regulation of Matrix Metalloproteinase 2

Ji-Min Seo, Sooyoung Park, Jae-Hong Kim

J Biol Chem. 2012 Apr 20; 287(17): 13840–13849. Published online 2012 Mar 6. doi: 10.1074/jbc.M111.317131

PMCID:: PMC3340142

Abstract Article PDF–3.5M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 245104115.

Involvement of the BLT₂ receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice

H J Kim, D K Kim, H Kim, J Y Koh, K M Kim, M S Noh, S Lee, S Kim, S H Park, J J Kim, S Y Kim, C H Lee

Br J Pharmacol. 2008 Jul; 154(5): 1073–1078. Published online 2008 Jun 9. doi: 10.1038/bjp.2008.220

PMCID:: PMC2451041

Abstract Article PDF–156K

Select item 229221616.

12(S)-hydroxyheptadeca-5Z, 8E, 10E–trienoic acid is a natural ligand for leukotriene B₄ receptor 2

Toshiaki Okuno, Yoshiko Iizuka, Hiroshi Okazaki, Takehiko Yokomizo, Ryo Taguchi, Takao Shimizu

J Exp Med. 2008 Apr 14; 205(4): 759–766. doi: 10.1084/jem.20072329

PMCID:: PMC2292216

Abstract Article PDF–1.9M

Select item 219322417.

Cell-Specific Transcriptional Regulation of Human Leukotriene B₄ Receptor Gene

Kazuhiko Kato, Takehiko Yokomizo, Takashi Izumi, Takao Shimizu

J Exp Med. 2000 Aug 7; 192(3): 413–420. doi: 10.1084/jem.192.3.413

PMCID:: PMC2193224

Abstract Article PDF–198K

Select item 219321718.

A Second Leukotriene B₄ Receptor, Blt2: A New Therapeutic Target in Inflammation and Immunological Disorders

Takehiko Yokomizo, Kazuhiko Kato, Kan Terawaki, Takashi Izumi, Takao Shimizu

J Exp Med. 2000 Aug 7; 192(3): 421–432. doi: 10.1084/jem.192.3.421

PMCID:: PMC2193217

Abstract Article PDF–220K

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 31099220.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

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