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Select item 105057321.

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Penny A. F. Whiley, Michael C. M. Luu, Liza O’Donnell, David J. Handelsman, Kate L. Loveland

Front Endocrinol (Lausanne) 2023; 14: 1234712. Published online 2023 Sep 1. doi: 10.3389/fendo.2023.1234712

PMCID:: PMC10505732

Abstract Article PDF–9.9M

Select item 103997092.

Immune escape of colorectal tumours via local LRH‐1/Cyp11b1‐mediated synthesis of immunosuppressive glucocorticoids

Asma Ahmed, Cindy Reinhold, Eileen Breunig, Truong San Phan, Lea Dietrich, Feodora Kostadinova, Corinne Urwyler, Verena M. Merk, Mario Noti, Israel Toja da Silva, Konstantin Bode, Fatima Nahle, Anna Pia Plazzo, Julia Koerner, Regula Stuber, Constantin Menche, Eva Karamitopoulou, Henner F. Farin, Kenneth J. Gollob, Thomas Brunner

Mol Oncol. 2023 Aug; 17(8): 1545–1566. Published online 2023 Mar 9. doi: 10.1002/1878-0261.13414

PMCID:: PMC10399709

Abstract Article PDF–3.7M

Select item 88437533.

Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse

Vijay K. Yadav, Julian M. Berger, Parminder Singh, Perumal Nagarajan, Gerard Karsenty

J Clin Invest. 2022 Feb 15; 132(4): e153752. Published online 2022 Feb 15. doi: 10.1172/JCI153752

PMCID:: PMC8843753

Abstract Article PDF–4.9M

Select item 72110354.

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate

Amélie Ménard, Nour Abou Nader, Adrien Levasseur, Guillaume St-Jean, Marie Le Gad-Le Roy, Derek Boerboom, Marie-Odile Benoit-Biancamano, Alexandre Boyer

Endocrinology. 2020 Jun; 161(6): bqaa052. Published online 2020 Apr 2. doi: 10.1210/endocr/bqaa052

PMCID:: PMC7211035

Abstract Article

Select item 64470815.

Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus

Matthew D. Taves, Paul R. Mittelstadt, Diego M. Presman, Gordon L. Hager, Jonathan D. Ashwell

Cell Rep. Author manuscript; available in PMC 2019 Apr 3.

Published in final edited form as: Cell Rep. 2019 Mar 26; 26(13): 3629–3642.e4. doi: 10.1016/j.celrep.2019.02.108

PMCID:: PMC6447081

Abstract Article PDF–2.1M

Select item 61816396.

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

Tatiana V. Novoselova, Mashal Hussain, Peter J. King, Leonardo Guasti, Louise A. Metherell, Marika Charalambous, Adrian J. L. Clark, Li F. Chan

FASEB J. 2018 Nov; 32(11): 6186–6196. Published online 2018 Jun 7. doi: 10.1096/fj.201701274RR

PMCID:: PMC6181639

Abstract Article

Select item 60786427.

Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy

Jessica A. Chadwick, Sarah A. Swager, Jeovanna Lowe, Steven S. Welc, James G. Tidball, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Jill A. Rafael-Fortney

Hum Mol Genet. 2016 Dec 1; 25(23): 5167–5177. Published online 2016 Oct 23. doi: 10.1093/hmg/ddw331

PMCID:: PMC6078642

Abstract Article PDF–668K

Select item 60748388.

Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function

A. Berthon, F.R. Faucz, S. Espiard, L. Drougat, J. Bertherat, C.A. Stratakis

Hum Mol Genet. 2017 Sep 15; 26(18): 3495–3507. Published online 2017 Jun 20. doi: 10.1093/hmg/ddx235

PMCID:: PMC6074838

Abstract Article PDF–2.2M

Select item 58400049.

De novo glucocorticoid synthesis by thymic epithelial cells regulates antigen-specific thymocyte selection

Paul R. Mittelstadt, Matthew D. Taves, Jonathan D. Ashwell

J Immunol. Author manuscript; available in PMC 2019 Mar 15.

Published in final edited form as: J Immunol. 2018 Mar 15; 200(6): 1988–1994. Published online 2018 Feb 9. doi: 10.4049/jimmunol.1701328

PMCID:: PMC5840004

Abstract Article PDF–743K

Select item 575227210.

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion

Marzia Scortegagna, Annabel Berthon, Nikolaos Settas, Andreas Giannakou, Guillermina Garcia, Jian-Liang Li, Brian James, Robert C. Liddington, José G. Vilches-Moure, Constantine A. Stratakis, Ze’ev A. Ronai

JCI Insight. 2017 Dec 7; 2(23): e97128. Published online 2017 Dec 7. doi: 10.1172/jci.insight.97128

PMCID:: PMC5752272

Abstract Article PDF–9.0M

Select item 567544411.

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1

Yewei Xing, Ken-ichirou Morohashi, Holly A. Ingraham, Gary D. Hammer

Development. 2017 Oct 15; 144(20): 3798–3807. doi: 10.1242/dev.150516

PMCID:: PMC5675444

Abstract Article

Select item 538122612.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 451399613.

A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo

Melda Şişecioğlu, Harun Budak, Lars Geffers, Murat Çankaya, Mehmet Çiftci, Christina Thaller, Gregor Eichele, Ömer İrfan Küfrevioğlu, Hasan Özdemir

J Lipid Res. 2015 Aug; 56(8): 1551–1559. doi: 10.1194/jlr.M059634

PMCID:: PMC4513996

Abstract Article PDF–3.4M

Select item 447572014.

Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors

Sergei G. Tevosian, Elizabeth Jiménez, Heather M. Hatch, Tianyu Jiang, Deborah A. Morse, Shawna C. Fox, Maria B. Padua

Endocrinology. 2015 Jul; 156(7): 2503–2517. Published online 2015 May 1. doi: 10.1210/en.2014-1815

PMCID:: PMC4475720

Abstract Article

Select item 439875615.

Combined Loss of the GATA4 and GATA6 Transcription Factors in Male Mice Disrupts Testicular Development and Confers Adrenal-Like Function in the Testes

Maria B. Padua, Tianyu Jiang, Deborah A. Morse, Shawna C. Fox, Heather M. Hatch, Sergei G. Tevosian

Endocrinology. 2015 May; 156(5): 1873–1886. Published online 2015 Feb 10. doi: 10.1210/en.2014-1907

PMCID:: PMC4398756

Abstract Article

Select item 403279116.

WT1 maintains adrenal-gonadal-primordium (AGP) identity and marks a novel population of AGP-like progenitors within the adult adrenal gland

Roberto Bandiera, Valerie P.I. Vidal, Fariba Ranc, Michael Clarkson, Isabelle Sahut-Barnola, Alexander von Gise, William T. Pu, Peter Hohenstein, Antoine Martinez, Andreas Schedl

Dev Cell. Author manuscript; available in PMC 2014 May 25.

Published in final edited form as: Dev Cell. 2013 Oct 14; 27(1): 5–18. doi: 10.1016/j.devcel.2013.09.003

PMCID:: PMC4032791

Abstract Article PDF–2.2M

Select item 394491617.

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung

Eric Boucher, Pierre R Provost, Yves Tremblay

BMC Res Notes. 2014; 7: 119. Published online 2014 Mar 1. doi: 10.1186/1756-0500-7-119

PMCID:: PMC3944916

Abstract Article PDF–844K

Select item 365057718.

FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development

Leonardo Guasti, W.C. Candy Sze, Tristan McKay, Richard Grose, Peter J. King

Mol Cell Endocrinol. 2013 May 22; 371(1-2): 182–188. doi: 10.1016/j.mce.2013.01.014

PMCID:: PMC3650577

Abstract Article PDF–1.4M

Select item 362802619.

Conditional Mutagenesis of Gata6 in SF1-Positive Cells Causes Gonadal-Like Differentiation in the Adrenal Cortex of Mice

Marjut Pihlajoki, Elisabeth Gretzinger, Rebecca Cochran, Antti Kyrönlahti, Anja Schrade, Theresa Hiller, Laura Sullivan, Michael Shoykhet, Erica L. Schoeller, Michael D. Brooks, Markku Heikinheimo, David B. Wilson

Endocrinology. 2013 May; 154(5): 1754–1767. Published online 2013 Mar 7. doi: 10.1210/en.2012-1892