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Items: 1 to 20 of 25

1.
The phagosomal solute transporter SLC15A4 promotes inflammasome activity via mTORC1 signaling and autophagy restraint in dendritic cells
Cynthia López‐Haber, Daniel J Netting, Zachary Hutchins, Xianghui Ma, Kathryn E Hamilton, Adriana R Mantegazza
EMBO J. 2022 Oct; 41(20): e111161. Published online 2022 Aug 29. doi: 10.15252/embj.2022111161
PMCID:
PMC9574736
AbstractArticlePDF–10M
2.
The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid–sensing TLRs and ligands to endolysosomes
Ivo Rimann, Rosana Gonzalez-Quintial, Roberto Baccala, William B. Kiosses, John R. Teijaro, Christopher G. Parker, Xiaohong Li, Bruce Beutler, Dwight H. Kono, Argyrios N. Theofilopoulos
Proc Natl Acad Sci U S A. 2022 Apr 5; 119(14): e2200544119. Published online 2022 Mar 29. doi: 10.1073/pnas.2200544119
PMCID:
PMC9169117
AbstractArticlePDF–1.7M
3.
The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models
Arna Katewa, Eric Suto, Jessica Hui, Jose Heredia, Jie Liang, Jason Hackney, Keith Anderson, Tuija M. Alcantar, Natasha Bacarro, Debra Dunlap, Jeffrey Eastham, Andres Paler-Martinez, Xin Y. Rairdan, Zora Modrusan, Wyne P. Lee, Cary D. Austin, Daniel Lafkas, Nico Ghilardi
PLoS One. 2021; 16(1): e0244439. Published online 2021 Jan 14. doi: 10.1371/journal.pone.0244439
PMCID:
PMC7808665
AbstractArticlePDF–3.2M
4.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
5.
A requirement for slc15a4 in imiquimod-induced systemic inflammation and psoriasiform inflammation in mice
Alexis D. Griffith, Asifa K. Zaidi, Ashley Pietro, Matthew Hadiono, Jessica S. Yang, Rachel Davis, Daniel L. Popkin
Sci Rep. 2018; 8: 14451. Published online 2018 Sep 27. doi: 10.1038/s41598-018-32668-9
PMCID:
PMC6160456
AbstractArticlePDF–5.2M
6.
SLC15A2 and SLC15A4 Mediate the Transport of Bacterially-Derived Di/Tripeptides to Enhance the NOD-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages
Yongjun Hu, Feifeng Song, Huidi Jiang, Gabriel Nuñez, David E. Smith
J Immunol. Author manuscript; available in PMC 2019 Jul 15.
Published in final edited form as: J Immunol. 2018 Jul 15; 201(2): 652–662. Published online 2018 May 21. doi: 10.4049/jimmunol.1800210
PMCID:
PMC6039277
AbstractArticlePDF–1.1M
7.
Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells
Toshihiko Kobayashi, Hidemitsu Tsutsui, Shiho Shimabukuro-Demoto, Reiko Yoshida-Sugitani, Hitomi Karyu, Kaori Furuyama-Tanaka, Daisuke Ohshima, Norihiro Kato, Tadashi Okamura, Noriko Toyama-Sorimachi
Int Immunol. 2017 Dec; 29(12): 551–566. Published online 2017 Nov 15. doi: 10.1093/intimm/dxx063
PMCID:
PMC5890901
AbstractArticlePDF–2.3M
8.
Semi-Mechanistic Population Pharmacokinetic Modeling of L-Histidine Disposition and Brain Uptake in Wildtype and Pht1 Null Mice
Xiao-Xing Wang, Yang-Bing Li, Meihua R. Feng, David E. Smith
Pharm Res. Author manuscript; available in PMC 2019 Jan 5.
Published in final edited form as: Pharm Res. 2018 Jan 5; 35(1): 19. Published online 2018 Jan 5. doi: 10.1007/s11095-017-2322-0
PMCID:
PMC5826761
AbstractArticlePDF–1.4M
9.
Induction of Systemic Autoimmunity by Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome/Endolysosome but Not Type I IFN
K. Michael Pollard, Gabriela M. Escalante, Hua Huang, Katarina M. Haraldsson, Per Hultman, Joseph M. Christy, Rahul D. Pawar, Jessica M. Mayeux, Rosana Gonzalez-Quintial, Roberto Baccala, Bruce Beutler, Argyrios N. Theofilopoulos, Dwight H. Kono
J Immunol. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: J Immunol. 2017 Dec 1; 199(11): 3739–3747. Published online 2017 Oct 20. doi: 10.4049/jimmunol.1700332
PMCID:
PMC5698107
AbstractArticlePDF–904K
10.
A Novel Role for PHT1 in the Disposition of L-Histidine in Brain: In Vitro Slice and In Vivo Pharmacokinetic Studies in Wildtype and Pht1 Null Mice
Xiao-Xing Wang, Yongjun Hu, Richard F. Keep, Noriko Toyama-Sorimachi, David E. Smith
Biochem Pharmacol. Author manuscript; available in PMC 2018 Jan 15.
Published in final edited form as: Biochem Pharmacol. 2017 Jan 15; 124: 94–102. Published online 2016 Nov 11. doi: 10.1016/j.bcp.2016.11.012
PMCID:
PMC5173442
AbstractArticlePDF–1.1M
11.
Neutrophils regulate humoral autoimmunity by restricting interferon gamma production via the generation of reactive oxygen species
Xinfang Huang, Jingjing Li, Stephanie Dorta-Estremera, Jeremy Di Domizio, Scott M. Anthony, Stephanie S. Watowich, Daniel Popkin, Zheng Liu, Philip Brohawn, Yihong Yao, Kimberly S. Schluns, Lewis L. Lanier, Wei Cao
Cell Rep. Author manuscript; available in PMC 2016 Aug 18.
Published in final edited form as: Cell Rep. 2015 Aug 18; 12(7): 1120–1132. Published online 2015 Aug 6. doi: 10.1016/j.celrep.2015.07.021
PMCID:
PMC4545388
AbstractArticlePDF–1.7M
12.
Divergent Developmental Expression and Function of the Proton-Coupled Oligopeptide Transporters PepT2 and PhT1 in Regional Brain Slices of Mouse and Rat
Yongjun Hu, Yehua Xie, Richard F. Keep, David E. Smith
J Neurochem. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: J Neurochem. 2014 Jun; 129(6): 955–965. Published online 2014 Mar 20. doi: 10.1111/jnc.12687
PMCID:
PMC4181614
AbstractArticlePDF–2.9M
13.
Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus
Roberto Baccala, Rosana Gonzalez-Quintial, Amanda L. Blasius, Ivo Rimann, Keiko Ozato, Dwight H. Kono, Bruce Beutler, Argyrios N. Theofilopoulos
Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): 2940–2945. Published online 2013 Feb 4. doi: 10.1073/pnas.1222798110
PMCID:
PMC3581947
AbstractArticlePDF–737K
14.
Slc15a4, a Gene Required for pDC Sensing of TLR Ligands, Is Required to Control Persistent Viral Infection
Amanda L. Blasius, Philippe Krebs, Brian M. Sullivan, Michael B. Oldstone, Daniel L. Popkin
PLoS Pathog. 2012 Sep; 8(9): e1002915. Published online 2012 Sep 13. doi: 10.1371/journal.ppat.1002915
PMCID:
PMC3441671
AbstractArticlePDF–966K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
17.
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
Amanda L. Blasius, Carrie N. Arnold, Philippe Georgel, Sophie Rutschmann, Yu Xia, Pei Lin, Charles Ross, Xiaohong Li, Nora G. Smart, Bruce Beutler
Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46): 19973–19978. Published online 2010 Nov 2. doi: 10.1073/pnas.1014051107
PMCID:
PMC2993408
AbstractArticlePDF–1.0M
18.
pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling
Jooeun Lee, Ivan Tattoli, Kacper A. Wojtal, Stephan R. Vavricka, Dana J. Philpott, Stephen E. Girardin
J Biol Chem. 2009 Aug 28; 284(35): 23818–23829. Published online 2009 Jul 1. doi: 10.1074/jbc.M109.033670
PMCID:
PMC2749154
AbstractArticlePDF–2.1M
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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