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Select item 111571521.

Nono induces Gadd45b to mediate DNA repair

Victoria Mamontova, Barbara Trifault, Kaspar Burger

Life Sci Alliance. 2024 Aug; 7(8): e202302555. Published online 2024 Jun 6. doi: 10.26508/lsa.202302555

PMCID:: PMC11157152

Abstract Article PDF–3.1M

Select item 104787532.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 103790853.

GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury

Ming Xie, Ruiyan Xie, Pengcheng Huang, Desmond Y. H. Yap, Peng Wu

Int J Mol Sci. 2023 Jul; 24(14): 11304. Published online 2023 Jul 11. doi: 10.3390/ijms241411304

PMCID:: PMC10379085

Abstract Article PDF–11M

Select item 100932694.

Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance

Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jr., Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik

Cells. 2023 Apr; 12(7): 1035. Published online 2023 Mar 28. doi: 10.3390/cells12071035

PMCID:: PMC10093269

Abstract Article PDF–21M

Select item 79532685.

Hepatic Gadd45β promotes hyperglycemia and glucose intolerance through DNA demethylation of PGC-1α

Ling Wu, Yang Jiao, Yao Li, Jingjing Jiang, Lin Zhao, Menghui Li, Bin Li, Zheng Yan, Xuejin Chen, Xiaoying Li, Yan Lu

J Exp Med. 2021 May 3; 218(5): e20201475. Published online 2021 Mar 10. doi: 10.1084/jem.20201475

PMCID:: PMC7953268

Abstract Article PDF–6.5M

Select item 77102776.

Inhibiting calpain 1 and 2 in cyclin G associated kinase–knockout mice mitigates podocyte injury

Xuefei Tian, Kazunori Inoue, Yan Zhang, Ying Wang, C. John Sperati, Christopher E. Pedigo, Tingting Zhao, Meihua Yan, Marwin Groener, Dennis G. Moledina, Karen Ebenezer, Wei Li, Zhenhai Zhang, Dan A. Liebermann, Lois Greene, Peter Greer, Chirag R. Parikh, Shuta Ishibe

JCI Insight. 2020 Nov 19; 5(22): e142740. Published online 2020 Nov 19. doi: 10.1172/jci.insight.142740

PMCID:: PMC7710277

Abstract Article PDF–5.2M

Select item 74123967.

Ablation of Gadd45β ameliorates the inflammation and renal fibrosis caused by unilateral ureteral obstruction

Sung‐Je Moon, Jae‐Hoon Kim, Young‐Keun Choi, Chul‐Ho Lee, Jung Hwan Hwang

J Cell Mol Med. 2020 Aug; 24(15): 8814–8825. Published online 2020 Jun 22. doi: 10.1111/jcmm.15519

PMCID:: PMC7412396

Abstract Article PDF–1.7M

Select item 68219128.

Gadd45β promotes regeneration after injury through TGFβ-dependent restitution in experimental colitis

Jung Hwan Hwang, Tae-Hwan Kim, Yong-Hoon Kim, Jung-Ran Noh, Dong-Hee Choi, Kyoung-Shim Kim, Eun-Young Lee, Byoung-Chan Kim, Myung Hee Kim, Ho Kim, Tae Geol Lee, Jong-Soo Lee, Chul-Ho Lee

Exp Mol Med. 2019 Oct; 51(10): 128. Published online 2019 Oct 30. doi: 10.1038/s12276-019-0335-y

PMCID:: PMC6821912

Abstract Article PDF–2.3M

Select item 66015119.

GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells

Katrin M. Schüle, Manuel Leichsenring, Tommaso Andreani, Viviana Vastolo, Medhavi Mallick, Michael U. Musheev, Emil Karaulanov, Christof Niehrs

Genes Dev. 2019 Jul 1; 33(13-14): 782–798. doi: 10.1101/gad.325696.119

PMCID:: PMC6601511

Abstract Article PDF–5.4M

Select item 642066210.

Gadd45b mediates depressive-like role through DNA demethylation

Benoit Labonté, Yun Ha Jeong, Eric Parise, Orna Issler, Mena Fatma, Olivia Engmann, Kyung-Ah Cho, Rachael Neve, Eric J. Nestler, Ja Wook Koo

Sci Rep. 2019; 9: 4615. Published online 2019 Mar 15. doi: 10.1038/s41598-019-40844-8

PMCID:: PMC6420662

Abstract Article PDF–1.4M

Select item 630097911.

PPARα activation drives demethylation of the CpG islands of the Gadd45b promoter in the mouse liver

Jung-Hwan Kim, Lilik Duwi Wahyudi, Kee K. Kim, Frank J. Gonzalez

Biochem Biophys Res Commun. Author manuscript; available in PMC 2018 Dec 20.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Aug 5; 476(4): 293–298. Published online 2016 May 24. doi: 10.1016/j.bbrc.2016.05.115

PMCID:: PMC6300979

Abstract Article PDF–1.5M

Select item 616179312.

Loss of Gadd45b accelerates BCR-ABL-driven CML

Xiaojin Sha, Barbara Hoffman, Dan A. Liebermann

Oncotarget. 2018 Sep 7; 9(70): 33360–33367. Published online 2018 Sep 7. doi: 10.18632/oncotarget.26076

PMCID:: PMC6161793

Abstract Article PDF–2.6M

Select item 593559513.

GADD45β loss ablates innate immunosuppression in cancer

Daniela Verzella, Jason Bennett, Mariafausta Fischietti, Anil K. Thotakura, Camilla Recordati, Fabio Pasqualini, Daria Capece, Davide Vecchiotti, Daniel D’Andrea, Barbara Di Francesco, Marcella De Maglie, Federica Begalli, Laura Tornatore, Salvatore Papa, Toby Lawrence, Stuart J. Forbes, Antonio Sica, Edoardo Alesse, Francesca Zazzeroni, Guido Franzoso

Cancer Res. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Cancer Res. 2018 Mar 1; 78(5): 1275–1292. Published online 2017 Dec 26. doi: 10.1158/0008-5472.CAN-17-1833

PMCID:: PMC5935595

Abstract Article PDF–3.1M

Select item 589924114.

Epigenetic modulation of intestinal Na⁺/H⁺ exchanger-3 expression

Anoop Kumar, Pooja Malhotra, Hayley Coffing, Shubha Priyamvada, Arivarasu N. Anbazhagan, Harish R. Krishnan, Ravinder K. Gill, Waddah A. Alrefai, David P. Gavin, Subhash C. Pandey, Pradeep K. Dudeja, Seema Saksena

Am J Physiol Gastrointest Liver Physiol. 2018 Mar 1; 314(3): G309–G318. Published online 2017 Nov 22. doi: 10.1152/ajpgi.00293.2017

PMCID:: PMC5899241

Abstract Article

Select item 572295015.

Input-dependent regulation of excitability controls dendritic maturation in somatosensory thalamocortical neurons

Laura Frangeul, Vassilis Kehayas, Jose V. Sanchez-Mut, Sabine Fièvre, K. Krishna-K, Gabrielle Pouchelon, Ludovic Telley, Camilla Bellone, Anthony Holtmaat, Johannes Gräff, Jeffrey D. Macklis, Denis Jabaudon

Nat Commun. 2017; 8: 2015. Published online 2017 Dec 8. doi: 10.1038/s41467-017-02172-1

PMCID:: PMC5722950

Abstract Article PDF–1.5M

Select item 567929916.

Peripheral deletion of CD8 T cells requires p38 mitogen activated protein kinase in cross-presenting dendritic cells

Trevor Smith, Xiaotian Lin, Marielle Mello, Kristi Marquardt, Jocelyn Cheung, Binfeng Lu, Linda A Sherman, Grégory Verdeil

J Immunol. Author manuscript; available in PMC 2018 Oct 15.

Published in final edited form as: J Immunol. 2017 Oct 15; 199(8): 2713–2720. Published online 2017 Sep 1. doi: 10.4049/jimmunol.1700427

PMCID:: PMC5679299

Abstract Article PDF–2.5M

Select item 510880717.

Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Müller Glia Dedifferentiation in a Murine Model of Retinal Injury

Luis I. Reyes-Aguirre, Monica Lamas

Front Neurosci. 2016; 10: 523. Published online 2016 Nov 15. doi: 10.3389/fnins.2016.00523

PMCID:: PMC5108807

Abstract Article PDF–2.4M

Select item 505362318.

Gadd45b deficiency promotes premature senescence and skin aging

Andrew Magimaidas, Priyanka Madireddi, Silvia Maifrede, Kaushiki Mukherjee, Barbara Hoffman, Dan A. Liebermann

Oncotarget. 2016 May 10; 7(19): 26935–26948. Published online 2016 Apr 20. doi: 10.18632/oncotarget.8854

PMCID:: PMC5053623

Abstract Article PDF–1.6M

Select item 494146019.

Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap

Joshua W. Vincentz, Jose J. Casasnovas, Ralston M. Barnes, Jianwen Que, David E. Clouthier, Jun Wang, Anthony B. Firulli

Proc Natl Acad Sci U S A. 2016 Jul 5; 113(27): 7563–7568. Published online 2016 Jun 22. doi: 10.1073/pnas.1603930113

PMCID:: PMC4941460

Abstract Article PDF–1.7M

Select item 488885520.

Fasting‐induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health

Jessica Fuhrmeister, Annika Zota, Tjeerd P Sijmonsma, Oksana Seibert, Şahika Cıngır, Kathrin Schmidt, Nicola Vallon, Roldan M de Guia, Katharina Niopek, Mauricio Berriel Diaz, Adriano Maida, Matthias Blüher, Jürgen G Okun, Stephan Herzig, Adam J Rose

EMBO Mol Med. 2016 Jun; 8(6): 654–669. Published online 2016 May 3. doi: 10.15252/emmm.201505801

PMCID:: PMC4888855

Abstract Article PDF–1.8M

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