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Items: 1 to 20 of 387

1.
HMGB1-Mediated Cell Death—A Crucial Element in Post-Hepatectomy Liver Failure
Laura Brunnthaler, Thomas G. Hammond, David Pereyra, Jonas Santol, Joel Probst, Valerie Laferl, Ulrike Resch, Monika Aiad, Anna Sofie Janoschek, Thomas Gruenberger, Hubert Hackl, Patrick Starlinger, Alice Assinger
Int J Mol Sci. 2024 Jul; 25(13): 7150. Published online 2024 Jun 28. doi: 10.3390/ijms25137150
PMCID:
PMC11241647
AbstractArticlePDF–4.3M
2.
Lupus autoantibodies initiate neuroinflammation sustained by continuous HMGB1:RAGE signaling and reversed by increased LAIR-1 expression
Kaitlin R. Carroll, Mark Mizrachi, Sean Simmons, Bahtiyar Toz, Czeslawa Kowal, Jeffrey Wingard, Nazila Tehrani, Aida Zarfeshani, Nina Kello, Lara El Khoury, Rachel Weissman-Tsukamoto, Joshua Z. Levin, Bruce T. Volpe, Betty Diamond
Nat Immunol. Author manuscript; available in PMC 2024 May 31.
Published in final edited form as: Nat Immunol. 2024 Apr; 25(4): 671–681. Published online 2024 Mar 6. doi: 10.1038/s41590-024-01772-6
PMCID:
PMC11141703
AbstractArticlePDF–4.0M
3.
Peripheral HMGB1 is linked to O3 pathology of disease‐associated astrocytes and amyloid
Chandrama Ahmed, Hendrik J. Greve, Carla Garza‐Lombo, Jamie A. Malley, James A. Johnson, Jr., Adrian L. Oblak, Michelle L. Block
Alzheimers Dement. 2024 May; 20(5): 3551–3566. Published online 2024 Apr 16. doi: 10.1002/alz.13825
PMCID:
PMC11095433
AbstractArticlePDF–7.8M
4.
Involvement of damage-associated molecular patterns in tumor response to photodynamic therapy: surface expression of calreticulin and high-mobility group box-1 release
Mladen Korbelik, Wei Zhang, Soroush Merchant
Cancer Immunol Immunother. 2011 Oct; 60(10): 1431–1437. Published online 2011 Jun 5. doi: 10.1007/s00262-011-1047-x
PMCID:
PMC11028986
AbstractArticlePDF–1.8M
5.
Tumor-derived high-mobility group box 1 and thymic stromal lymphopoietin are involved in modulating dendritic cells to activate T regulatory cells in a mouse model
Yi Zhang, Zuqiang Liu, Xingxing Hao, Ang Li, Jiying Zhang, Cara D. Carey, Louis D. Falo, Zhaoyang You
Cancer Immunol Immunother. 2018 Mar; 67(3): 353–366. Published online 2017 Nov 7. doi: 10.1007/s00262-017-2087-7
PMCID:
PMC11028122
AbstractArticlePDF–757K
6.
Downregulation of HMGB1 carried by macrophage-derived extracellular vesicles delays atherosclerotic plaque formation through Caspase-11-dependent macrophage pyroptosis
Weijie Liang, Ruibin Wei, Xingxing Zhu, Jinliang Li, Aiwen Lin, Jun Chen, Wen Wu, Qiang Jie
Mol Med. 2024; 30: 38. Published online 2024 Mar 16. doi: 10.1186/s10020-023-00753-z
PMCID:
PMC10943908
AbstractArticlePDF–1.8M
7.
APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
Nicole Koutsodendris, Jessica Blumenfeld, Ayushi Agrawal, Michela Traglia, Oscar Yip, Antara Rao, Min Joo Kim, Maxine R. Nelson, Yung-Hua Wang, Brian Grone, Yanxia Hao, Reuben Thomas, Misha Zilberter, Seo Yeon Yoon, Patrick Arriola, Yadong Huang
Cell Rep. Author manuscript; available in PMC 2024 Feb 16.
Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113252. Published online 2023 Oct 19. doi: 10.1016/j.celrep.2023.113252
PMCID:
PMC10873109
AbstractArticlePDF–4.4M
8.
MiR129-5p-loaded exosomes suppress seizure-associated neurodegeneration in status epilepticus model mice by inhibiting HMGB1/TLR4-mediated neuroinflammation
Tengfei Liu, Haiyan Liu, Siyi Xue, Lijie Xiao, Jing Xu, Shuyan Tong, Xiu’e Wei
Mol Biol Rep. 2024; 51(1): 292. Published online 2024 Feb 8. doi: 10.1007/s11033-024-09215-z
PMCID:
PMC10853309
AbstractArticlePDF–4.6M
9.
Blockade of HMGB1 Reduces Inflammation and Pruritus in Atopic Dermatitis by Inhibiting Skin Fibroblasts Activation
Lingxuan Zhou, Xiaohui Yuan, Yongyan Hu, Siyu Zhu, Junxiang Li, Chenyu Wang, Miao Jing, Lingling Liu, Zhe Xu, Zuotao Zhao, Jiahui Zhao
Int Arch Allergy Immunol. 2024 Feb; 185(2): 170–181. Published online 2023 Nov 14. doi: 10.1159/000534568
PMCID:
PMC10836909
AbstractArticle
10.
Age-Dependent and Aβ-Induced Dynamic Changes in the Subcellular Localization of HMGB1 in Neurons and Microglia in the Brains of an Animal Model of Alzheimer’s Disease
Song-I Seol, Dashdulam Davaanyam, Sang-A Oh, Eun-Hwa Lee, Pyung-Lim Han, Seung-Woo Kim, Ja-Kyeong Lee
Cells. 2024 Jan; 13(2): 189. Published online 2024 Jan 18. doi: 10.3390/cells13020189
PMCID:
PMC10814163
AbstractArticlePDF–4.7M
11.
Vesicular HMGB1 release from neurons stressed with spreading depolarization enables confined inflammatory signaling to astrocytes
Zeynep Kaya, Nevin Belder, Melike Sever-Bahcekapili, Buket Donmez-Demir, Şefik Evren Erdener, Naz Bozbeyoglu, Canan Bagci, Emine Eren-Kocak, Muge Yemisci, Hulya Karatas, Esra Erdemli, Ihsan Gursel, Turgay Dalkara
J Neuroinflammation. 2023; 20: 295. Published online 2023 Dec 11. doi: 10.1186/s12974-023-02977-6
PMCID:
PMC10712196
AbstractArticlePDF–2.9M
12.
High-mobility group box-1 impedes skeletal muscle regeneration via downregulation of Pax-7 synthesis by increasing miR-342-5p expression
Trung-Loc Ho, Yu-Liang Lai, Chin-Jung Hsu, Chen-Ming Su, Chih-Hsin Tang
Aging (Albany NY) 2023 Nov 15; 15(21): 12618–12632. Published online 2023 Nov 13. doi: 10.18632/aging.205202
PMCID:
PMC10683625
AbstractArticlePDF–1.4M
13.
HMGB1 Release Induced by EV71 Infection Exacerbates Blood-Brain Barrier Disruption via VE-cadherin Phosphorylation
Qiao You, Jing Wu, Ye Liu, Fang Zhang, Na Jiang, Xiaoyan Tian, Yurong Cai, Enhui Yang, Ruining Lyu, Nan Zheng, Deyan Chen, Zhiwei Wu
Virus Res. 2023 Dec; 338: 199240. Published online 2023 Oct 14. doi: 10.1016/j.virusres.2023.199240
PMCID:
PMC10587765
AbstractArticlePDF–4.1M
14.
HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma
Joelle S. Suarez, Flavia Novelli, Keisuke Goto, Michiko Ehara, Mika Steele, Jin-Hee Kim, Alicia A. Zolondick, Jiaming Xue, Ronghui Xu, Mai Saito, Sandra Pastorino, Michael Minaai, Yasutaka Takanishi, Mitsuru Emi, Ian Pagano, Andrew Wakeham, Thorsten Berger, Harvey I. Pass, Giovanni Gaudino, Tak W. Mak, Michele Carbone, Haining Yang
Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2307999120. Published online 2023 Sep 20. doi: 10.1073/pnas.2307999120
PMCID:
PMC10523480
AbstractArticlePDF–4.1M
15.
Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea
Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong
Eur J Histochem. 2023 Jul 26; 67(3): 3704. Published online 2023 Sep 1. doi: 10.4081/ejh.2023.3704
PMCID:
PMC10518653
AbstractArticlePDF–23M
16.
Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality
Gurvinder Kaur, Rebecca A. Helmer, Dalia Martinez-Marin, Souad R. Sennoune, Rachel L. Washburn, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton
PLoS One. 2023; 18(8): e0286109. Published online 2023 Aug 25. doi: 10.1371/journal.pone.0286109
PMCID:
PMC10456192
AbstractArticlePDF–3.7M
17.
Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation
Moises Freitas-Andrade, Cesar H. Comin, Peter Van Dyken, Julie Ouellette, Joanna Raman-Nair, Nicole Blakeley, Qing Yan Liu, Sonia Leclerc, Youlian Pan, Ziying Liu, Micaël Carrier, Karan Thakur, Alexandre Savard, Gareth M. Rurak, Marie-Ève Tremblay, Natalina Salmaso, Luciano da F. Costa, Gianfilippo Coppola, Baptiste Lacoste
Nat Commun. 2023; 14: 4965. Published online 2023 Aug 16. doi: 10.1038/s41467-023-40682-3
PMCID:
PMC10432480
AbstractArticlePDF–20M
18.
Repeated Social Defeat Stress Induces HMGB1 Nuclear Export in Prefrontal Neurons, Leading to Social Avoidance in Mice
Shiho Kitaoka, Ayaka Tomohiro, Shinya Ukeshima, Keyue Liu, Hidenori Wake, Shinya H. Kimura, Yasuhiko Yamamoto, Masahiro Nishibori, Tomoyuki Furuyashiki
Cells. 2023 Jul; 12(13): 1789. Published online 2023 Jul 5. doi: 10.3390/cells12131789
PMCID:
PMC10340449
AbstractArticlePDF–2.2M
19.
Hepatic depletion of nucleolar protein mDEF causes excessive mitochondrial copper accumulation associated with p53 and NRF1 activation
Jinsong Wei, Shuai Wang, Haozhe Zhu, Wei Cui, Jianan Gao, Ce Gao, Bo Yu, Bojing Liu, Jun Chen, Jinrong Peng
iScience. 2023 Jul 21; 26(7): 107220. Published online 2023 Jun 26. doi: 10.1016/j.isci.2023.107220
PMCID:
PMC10339200
AbstractArticlePDF–7.3M
20.
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis: Nrf2/HMGB1 affects osteoarthritis
Wenzhao Li, Cheng Tao, Minzhi Mao, Kewei Zhu
Acta Biochim Biophys Sin (Shanghai) 2023 May; 55(5): 818–830. Published online 2023 May 26. doi: 10.3724/abbs.2023078
PMCID:
PMC10281874
AbstractArticlePDF–2.5M

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