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Select item 112511671.

MCM8 interacts with DDX5 to promote R-loop resolution

Canxin Wen, Lili Cao, Shuhan Wang, Weiwei Xu, Yongze Yu, Simin Zhao, Fan Yang, Zi-Jiang Chen, Shidou Zhao, Yajuan Yang, Yingying Qin

EMBO J. 2024 Jul; 43(14): 3044–3071. Published online 2024 Jun 10. doi: 10.1038/s44318-024-00134-0

PMCID:: PMC11251167

Abstract Article PDF–8.7M

Select item 109594152.

FOXL2 interaction with different binding partners regulates the dynamics of ovarian development

Roberta Migale, Michelle Neumann, Richard Mitter, Mahmoud-Reza Rafiee, Sophie Wood, Jessica Olsen, Robin Lovell-Badge

Sci Adv. 2024 Mar 22; 10(12): eadl0788. Published online 2024 Mar 22. doi: 10.1126/sciadv.adl0788

PMCID:: PMC10959415

Abstract Article PDF–4.4M

Select item 109098933.

MAX controls meiotic entry in sexually undifferentiated germ cells

Ayumu Suzuki, Kousuke Uranishi, Masazumi Nishimoto, Yosuke Mizuno, Seiya Mizuno, Satoru Takahashi, Robert N. Eisenman, Akihiko Okuda

Sci Rep. 2024; 14: 5236. Published online 2024 Mar 4. doi: 10.1038/s41598-024-55506-7

PMCID:: PMC10909893

Abstract Article PDF–7.0M

Select item 107535874.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 106541015.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 106264436.

Nutritional and metabolic control of germ cell fate through O‐GlcNAc regulation

Yohei Hayashi, Yukiko Tando, Yumi Ito‐Matsuoka, Kaho Ikuta, Asuka Takehara, Katsutaro Morino, Hiroshi Maegawa, Yasuhisa Matsui

EMBO Rep. 2023 Nov; 24(11): e56845. Published online 2023 Oct 16. doi: 10.15252/embr.202356845

PMCID:: PMC10626443

Abstract Article PDF–2.9M

Select item 105772787.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 105206378.

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun

Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940

PMCID:: PMC10520637

Abstract Article PDF–6.6M

Select item 105057329.

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Penny A. F. Whiley, Michael C. M. Luu, Liza O’Donnell, David J. Handelsman, Kate L. Loveland

Front Endocrinol (Lausanne) 2023; 14: 1234712. Published online 2023 Sep 1. doi: 10.3389/fendo.2023.1234712

PMCID:: PMC10505732

Abstract Article PDF–9.9M

Select item 1042615410.

FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin, Zi-Jiang Chen

BMC Biol. 2023; 21: 174. Published online 2023 Aug 15. doi: 10.1186/s12915-023-01676-1

PMCID:: PMC10426154

Abstract Article PDF–6.6M

Select item 1041512811.

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development

Adda-Lee Graham-Paquin, Deepak Saini, Jacinthe Sirois, Ishtiaque Hossain, Megan S Katz, Qinwei Kim-Wee Zhuang, Sin Young Kwon, Yojiro Yamanaka, Guillaume Bourque, Maxime Bouchard, William A Pastor

Nucleic Acids Res. 2023 Aug 11; 51(14): 7314–7329. Published online 2023 Jul 3. doi: 10.1093/nar/gkad540

PMCID:: PMC10415128

Abstract Article PDF–2.6M

Select item 1039049212.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1025966013.

DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement

Aushaq B. Malla, Shannon R. Rainsford, Zachary D. Smith, Bluma J. Lesch

Development. 2023 May 1; 150(9): dev201497. Published online 2023 May 12. doi: 10.1242/dev.201497

PMCID:: PMC10259660

Abstract Article

Select item 1016458214.

SPIDR is required for homologous recombination during mammalian meiosis

Tao Huang, Xinyue Wu, Shiyu Wang, Ziyou Bao, Yanling Wan, Ziqi Wang, Mengjing Li, Xiaochen Yu, Yue Lv, Zhaojian Liu, Xiangfeng Chen, Wai-Yee Chan, Fei Gao, Gang Lu, Zi-Jiang Chen, Hongbin Liu

Nucleic Acids Res. 2023 May 8; 51(8): 3855–3868. Published online 2023 Mar 20. doi: 10.1093/nar/gkad154

PMCID:: PMC10164582

Abstract Article PDF–11M

Select item 1015134315.

The Mc4r gene is responsible for the development of experimentally induced testicular teratomas

Syunsuke Seki, Kaoru Ohura, Takehiro Miyazaki, Abdullah An Naser, Shuji Takabayashi, Eisei Tsutsumi, Toshinobu Tokumoto

Sci Rep. 2023; 13: 6756. Published online 2023 May 1. doi: 10.1038/s41598-023-32784-1

PMCID:: PMC10151343

Abstract Article PDF–2.2M

Select item 1008603316.

LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway

Jung-Hsuan Chang, Chia-Hua Chou, Jui-Ching Wu, Keng-Mao Liao, Wei-Jia Luo, Wei-Lun Hsu, Xuan-Ren Chen, Sung-Liang Yu, Szu-Hua Pan, Pan-Chyr Yang, Kang-Yi Su

Commun Biol. 2023; 6: 389. Published online 2023 Apr 10. doi: 10.1038/s42003-023-04778-2

PMCID:: PMC10086033

Abstract Article PDF–5.9M

Select item 1001770317.

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco

Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0

PMCID:: PMC10017703

Abstract Article PDF–16M

Select item 997409518.

TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis

Chengzi Huang, Simin Zhao, Yajuan Yang, Ting Guo, Hanni Ke, Xin Mi, Yingying Qin, Zi-Jiang Chen, Shidou Zhao

J Clin Invest. 2023 Mar 1; 133(5): e162315. Published online 2023 Mar 1. doi: 10.1172/JCI162315

PMCID:: PMC9974095

Abstract Article PDF–3.1M

Select item 997132019.

DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development

Simin Zhao, Chengzi Huang, Yajuan Yang, Weiwei Xu, Yongze Yu, Canxin Wen, Lili Cao, Fei Gao, Yingying Qin, Zi-Jiang Chen, Ting Guo, Shidou Zhao

J Biol Chem. 2023 Mar; 299(3): 102905. Published online 2023 Jan 13. doi: 10.1016/j.jbc.2023.102905

PMCID:: PMC9971320

Abstract Article PDF–4.2M

Select item 977234620.

SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse

Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, Atsuo Ogura, Masami Kanai-Azuma, Akihiko Kudo, Yoshiakira Kanai

Nat Commun. 2022; 13: 7860. Published online 2022 Dec 21. doi: 10.1038/s41467-022-35465-1