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Items: 1 to 20 of 46

1.
Knockout mice with pituitary malformations help identify human cases of hypopituitarism
Julian Martinez-Mayer, Michelle L. Brinkmeier, Sean P. O’Connell, Arnold Ukagwu, Marcelo A. Marti, Mirta Miras, Maria V. Forclaz, Maria G. Benzrihen, Leonard Y. M. Cheung, Sally A. Camper, Buffy S. Ellsworth, Lori T. Raetzman, Maria I. Pérez-Millán, Shannon W. Davis
Genome Med. 2024; 16: 75. Published online 2024 May 31. doi: 10.1186/s13073-024-01347-y
PMCID:
PMC11140907
AbstractArticlePDF–4.4M
2.
BRD2 promotes antibody class switch recombination by facilitating DNA repair in collaboration with NIPBL
Santosh K Gothwal, Ahmed M Refaat, Mikiyo Nakata, Andre Stanlie, Tasuku Honjo, Nasim A Begum
Nucleic Acids Res. 2024 May 8; 52(8): 4422–4439. Published online 2024 Apr 3. doi: 10.1093/nar/gkae204
PMCID:
PMC11077081
AbstractArticlePDF–2.5M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
TRF2-mediated telomere protection is dispensable in pluripotent stem cells
Marta Markiewicz-Potoczny, Anastasia Lobanova, Anisha M. Loeb, Oktay Kirak, Teresa Olbrich, Sergio Ruiz, Eros Lazzerini Denchi
Nature. Author manuscript; available in PMC 2022 Jun 2.
Published in final edited form as: Nature. 2021 Jan; 589(7840): 110–115. Published online 2020 Nov 25. doi: 10.1038/s41586-020-2959-4
PMCID:
PMC9161009
AbstractArticlePDF–5.8M
5.
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death
Farrah El-Saafin, Maria I. Bergamasco, Yunshun Chen, Rose E. May, Prabagaran Esakky, Soroor Hediyeh-zadeh, Mathew Dixon, Stephen Wilcox, Melissa J. Davis, Andreas Strasser, Gordon K. Smyth, Tim Thomas, Anne K. Voss
Cell Death Differ. 2022 May; 29(5): 1013–1027. Published online 2022 Mar 31. doi: 10.1038/s41418-022-00982-5
PMCID:
PMC9091217
AbstractArticlePDF–7.2M
6.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
7.
BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos
Mami Tsume-Kajioka, Chiharu Kimura-Yoshida, Kyoko Mochida, Yoko Ueda, Isao Matsuo
BMC Biol. 2022; 20: 64. Published online 2022 Mar 9. doi: 10.1186/s12915-022-01251-0
PMCID:
PMC8905768
AbstractArticlePDF–10M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice
Shilpa Pathak, William C. L. Stewart, Christin E. Burd, Mark E. Hester, David A. Greenberg
PLoS One. 2020; 15(6): e0234910. Published online 2020 Jun 19. doi: 10.1371/journal.pone.0234910
PMCID:
PMC7304595
AbstractArticlePDF–1.7M
10.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
11.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
12.
HDAC11 suppresses the thermogenic program of adipose tissue via BRD2
Rushita A. Bagchi, Bradley S. Ferguson, Matthew S. Stratton, Tianjing Hu, Maria A. Cavasin, Lei Sun, Ying-Hsi Lin, Dianxin Liu, Pilar Londono, Kunhua Song, Maria F. Pino, Lauren M. Sparks, Steven R. Smith, Philipp E. Scherer, Sheila Collins, Edward Seto, Timothy A. McKinsey
JCI Insight. 2018 Aug 9; 3(15): e120159. Published online 2018 Aug 9. doi: 10.1172/jci.insight.120159
PMCID:
PMC6129125
AbstractArticlePDF–3.0M
13.
The BET protein BRD2 cooperates with CTCF to enforce transcriptional and architectural boundaries
Sarah C. Hsu, Thomas G. Gilgenast, Caroline R. Bartman, Christopher R. Edwards, Aaron J. Stonestrom, Peng Huang, Daniel J. Emerson, Perry Evans, Michael T. Werner, Cheryl A. Keller, Belinda Giardine, Ross C. Hardison, Arjun Raj, Jennifer E. Phillips-Cremins, Gerd A. Blobel
Mol Cell. Author manuscript; available in PMC 2018 Apr 6.
Published in final edited form as: Mol Cell. 2017 Apr 6; 66(1): 102–116.e7. doi: 10.1016/j.molcel.2017.02.027
PMCID:
PMC5393350
AbstractArticlePDF–1.1M
14.
A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)
Stefan H. Geyer, Lukas Reissig, Julia Rose, Robert Wilson, Fabrice Prin, Dorota Szumska, Ramiro Ramirez‐Solis, Catherine Tudor, Jacqui White, Timothy J. Mohun, Wolfgang J. Weninger
J Anat. 2017 May; 230(5): 710–719. Published online 2017 Feb 9. doi: 10.1111/joa.12590
PMCID:
PMC5382591
AbstractArticlePDF–1.5M
15.
Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation
Ka Lung Cheung, Fan Zhang, Anbalagan Jaganathan, Rajal Sharma, Qiang Zhang, Tsuyoshi Konuma, Tong Shen, June-Yong Lee, Chunyan Ren, Chih-Hung Chen, Geming Lu, Matthew R. Olson, Weijia Zhang, Mark H. Kaplan, Dan R. Littman, Martin J. Walsh, Huabao Xiong, Lei Zeng, Ming-Ming Zhou
Mol Cell. Author manuscript; available in PMC 2018 Mar 16.
Published in final edited form as: Mol Cell. 2017 Mar 16; 65(6): 1068–1080.e5. Published online 2017 Mar 3. doi: 10.1016/j.molcel.2016.12.022
PMCID:
PMC5357147
AbstractArticlePDF–3.0M
16.
H2A.Z.1 mono-ubiquitylation antagonizes BRD2 to maintain poised chromatin in ESCs
Lauren E. Surface, Paul A. Fields, Vidya Subramanian, Russell Behmer, Namrata Udeshi, Sally E. Peach, Jacob D. Jaffe, Laurie A. Boyer
Cell Rep. Author manuscript; available in PMC 2016 Mar 9.
Published in final edited form as: Cell Rep. 2016 Feb 9; 14(5): 1142–1155. Published online 2016 Jan 21. doi: 10.1016/j.celrep.2015.12.100
PMCID:
PMC4764991
AbstractArticlePDF–2.4M
17.
The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene
Nadezhda Logunova, Maria Korotetskaya, Vladimir Polshakov, Alexander Apt
PLoS Genet. 2015 Nov; 11(11): e1005672. Published online 2015 Nov 30. doi: 10.1371/journal.pgen.1005672
PMCID:
PMC4664271
AbstractArticlePDF–8.4M
18.
Sex-specific behavioral traits in the Brd2 mouse model of Juvenile Myoclonic Epilepsy
Tamar Chachua, Cezar Goletiani, Giorgi Maglakelidze, Galyna Sidyelyeva, Margaret Daniel, Emily Morris, James Miller, Enyuan Shang, Debra J. Wolgemuth, David A. Greenberg, Jana Velíšková, Libor Velíšek
Genes Brain Behav. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Genes Brain Behav. 2014 Sep; 13(7): 702–712. Published online 2014 Aug 28. doi: 10.1111/gbb.12160
PMCID:
PMC4186774
AbstractArticlePDF–1.3M
19.
Brd2 gene disruption causes ‘metabolically healthy’ obesity: Epigenetic and chromatin-based mechanisms that uncouple obesity from Type 2 diabetes
Fangnian Wang, Jude T. Deeney, Gerald V. Denis
Vitam Horm. Author manuscript; available in PMC 2014 Feb 25.
Published in final edited form as: Vitam Horm. 2013; 91: 49–75. doi: 10.1016/B978-0-12-407766-9.00003-1
PMCID:
PMC3934552
AbstractArticlePDF–485K
20.
The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis
Anna C. Belkina, Wanda P. Blanton, Barbara S. Nikolajczyk, Gerald V. Denis
J Leukoc Biol. 2014 Mar; 95(3): 451–460. doi: 10.1189/jlb.1112588
PMCID:
PMC3923082
AbstractArticle

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