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Items: 1 to 20 of 39

1.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
2.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
circRNA_141539 can serve as an oncogenic factor in esophageal squamous cell carcinoma by sponging miR-4469 and activating CDK3 gene
Zheng-hua Liu, Shi-ze Yang, Wen-ya Li, Si-yuan Dong, Si-yu Zhou, Shun Xu
Aging (Albany NY) 2021 Apr 30; 13(8): 12179–12193. Published online 2021 Jan 27. doi: 10.18632/aging.103071
PMCID:
PMC8109109
AbstractArticlePDF–1.6M
5.
ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells
Jaya Bhushan, Joshua B. Radke, Yi-Chieh Perng, Michael Mcallaster, Deborah J. Lenschow, Herbert W. Virgin, L. David Sibley
mBio. 2020 Sep-Oct; 11(5): e00852-20. Published online 2020 Oct 6. doi: 10.1128/mBio.00852-20
PMCID:
PMC7542356
AbstractArticlePDF–2.4M
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice
Steven Findlay, John Heath, Vincent M Luo, Abba Malina, Théo Morin, Yan Coulombe, Billel Djerir, Zhigang Li, Arash Samiei, Estelle Simo‐Cheyou, Martin Karam, Halil Bagci, Dolev Rahat, Damien Grapton, Elise G Lavoie, Christian Dove, Husam Khaled, Hellen Kuasne, Koren K Mann, Kathleen Oros Klein, Celia M Greenwood, Yuval Tabach, Morag Park, Jean‐Francois Côté, Jean‐Yves Masson, Alexandre Maréchal, Alexandre Orthwein
EMBO J. 2018 Sep 14; 37(18): e100158. Published online 2018 Aug 28. doi: 10.15252/embj.2018100158
PMCID:
PMC6138439
AbstractArticlePDF–1.1M
8.
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel
eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879
PMCID:
PMC5999396
AbstractArticlePDF–3.6M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn
Cell Syst. Author manuscript; available in PMC 2017 Sep 28.
Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001
PMCID:
PMC5455996
AbstractArticlePDF–3.1M
11.
Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer
T Xiao, J J Zhu, S Huang, C Peng, S He, J Du, R Hong, X Chen, A M Bode, W Jiang, Z Dong, D Zheng
Oncogene. 2017 May 18; 36(20): 2835–2845. Published online 2016 Nov 28. doi: 10.1038/onc.2016.434
PMCID:
PMC5442426
AbstractArticlePDF–3.4M
12.
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family
Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang
Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277
PMCID:
PMC5013315
AbstractArticlePDF–3.2M
13.
Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis
Jinping Lu, Zhen Lin Zhang, Damao Huang, Na Tang, Yuejin Li, Zhengke Peng, Chengrong Lu, Zigang Dong, Faqing Tang
Oncotarget. 2016 Feb 9; 7(6): 7012–7028. Published online 2016 Jan 9. doi: 10.18632/oncotarget.6875
PMCID:
PMC4872765
AbstractArticlePDF–2.9M
14.
Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1
Zhenghong Lin, Can Tan, Quan Qiu, Sinyi Kong, Heeyoung Yang, Fang Zhao, Zhaojian Liu, Jinping Li, Qingfei Kong, Beixue Gao, Terry Barrett, Guang-Yu Yang, Jianing Zhang, Deyu Fang
Cell Discov. 2015; 1: 15028. Published online 2015 Oct 13. doi: 10.1038/celldisc.2015.28
PMCID:
PMC4809424
AbstractArticlePDF–3.3M
15.
miR-214/199a/199a* cluster levels predict poor survival in hepatocellular carcinoma through interference with cell-cycle regulators
Peipei Wang, Song Chen, He Fang, Xiaojuan Wu, Dabiao Chen, Liang Peng, Zhiliang Gao, Chan Xie
Oncotarget. 2016 Jan 5; 7(1): 929–945. Published online 2015 Oct 19. doi: 10.18632/oncotarget.6137
PMCID:
PMC4808043
AbstractArticlePDF–1.4M
16.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
17.
Global mapping of herpesvirus-host protein complexes reveals a novel transcription strategy for late genes
Zoe H. Davis, Erik Verschueren, Gwendolyn M. Jang, Kevin Kleffman, Jeffrey R. Johnson, Jimin Park, John Von Dollen, M. Cyrus Maher, Tasha Johnson, William Newton, Stefanie Jäger, Michael Shales, Julie Horner, Ryan D. Hernandez, Nevan J. Krogan, Britt A. Glaunsinger
Mol Cell. Author manuscript; available in PMC 2016 Jan 22.
Published in final edited form as: Mol Cell. 2015 Jan 22; 57(2): 349–360. Published online 2014 Dec 24. doi: 10.1016/j.molcel.2014.11.026
PMCID:
PMC4305015
AbstractArticlePDF–1.9M
18.
Cyclin C is a haploinsufficient tumor suppressor
Na Li, Anne Fassl, Joel Chick, Hiroyuki Inuzuka, Xiaoyu Li, Marc R. Mansour, Lijun Liu, Haizhen Wang, Bryan King, Shavali Shaik, Alejandro Gutierrez, Alban Ordureau, Tobias Otto, Taras Kreslavsky, Lukas Baitsch, Leah Bury, Clifford A. Meyer, Nan Ke, Kristin A. Mulry, Michael J. Kluk, Moni Roy, Sunkyu Kim, Xiaowu Zhang, Yan Geng, Agnieszka Zagozdzon, Sarah Jenkinson, Rosemary E. Gale, David C. Linch, Jean J. Zhao, Charles G. Mullighan, J. Wade Harper, Jon C. Aster, Iannis Aifantis, Harald von Boehmer, Steven P. Gygi, Wenyi Wei, A. Thomas Look, Piotr Sicinski
Nat Cell Biol. Author manuscript; available in PMC 2015 May 1.
Published in final edited form as: Nat Cell Biol. 2014 Nov; 16(11): 1080–1091. Published online 2014 Oct 26. doi: 10.1038/ncb3046
PMCID:
PMC4235773
AbstractArticlePDF–4.3M
19.
PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair
Hanan Khoury-Haddad, Noga Guttmann-Raviv, Inbal Ipenberg, David Huggins, Anand D. Jeyasekharan, Nabieh Ayoub
Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7): E728–E737. Published online 2014 Feb 3. doi: 10.1073/pnas.1317585111
PMCID:
PMC3932863
AbstractArticlePDF–1.6M
20.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M

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