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Select item 111158701.

The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition

Chiara Giommarelli, Valentina Zuco, Enrica Favini, Claudio Pisano, Fabrizio Dal Piaz, Nunziatina De Tommasi, Franco Zunino

Cell Mol Life Sci. 2010 Mar; 67(6): 995–1004. Published online 2009 Dec 29. doi: 10.1007/s00018-009-0233-x

PMCID:: PMC11115870

Abstract Article PDF–432K

Select item 111156392.

Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells

Giovanni Di Maira, Francesca Brustolon, Lorenzo A. Pinna, Maria Ruzzene

Cell Mol Life Sci. 2009 Oct; 66(20): 3363–3373. Published online 2009 Aug 8. doi: 10.1007/s00018-009-0108-1

PMCID:: PMC11115639

Abstract Article PDF–492K

Select item 111053183.

RIPK4 activity in keratinocytes is controlled by the SCF^β-TrCP ubiquitin ligase to maintain cortical actin organization

Giel Tanghe, Corinne Urwyler-Rösselet, Philippe De Groote, Emmanuel Dejardin, Pieter-Jan De Bock, Kris Gevaert, Peter Vandenabeele, Wim Declercq

Cell Mol Life Sci. 2018 Aug; 75(15): 2827–2841. Published online 2018 Feb 12. doi: 10.1007/s00018-018-2763-6

PMCID:: PMC11105318

Abstract Article PDF–2.2M

Select item 110733044.

USP35 dimer prevents its degradation by E3 ligase CHIP through auto-deubiquitinating activity

Jinyoung Park, Sang Chul Shin, Kyeong Sik Jin, Min Joon Lim, Yeojin Kim, Eunice EunKyeong Kim, Eun Joo Song

Cell Mol Life Sci. 2023 Apr; 80(4): 112. Published online 2023 Apr 1. doi: 10.1007/s00018-023-04740-9

PMCID:: PMC11073304

Abstract Article PDF–4.6M

Select item 110374475.

HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus

Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Tomonori Furukawa, Yuko Shiba, Terrance M. Egan, Shinya Ueno

Mol Pharmacol. 2016 Aug; 90(2): 116–126. Published online 2016 Aug. doi: 10.1124/mol.115.102988

PMCID:: PMC11037447

Abstract Article PDF–1.8M

Select item 109925276.

Circ-HSP90A expedites cell growth, stemness, and immune evasion in non-small cell lung cancer by regulating STAT3 signaling and PD-1/PD-L1 checkpoint

Jie Lei, Jianfei Zhu, Bengang Hui, Chenghui Jia, Xiaolong Yan, Tao Jiang, Xiaoping Wang

Cancer Immunol Immunother. 2023 Jan; 72(1): 101–124. Published online 2022 Jun 24. doi: 10.1007/s00262-022-03235-z

PMCID:: PMC10992527

Abstract Article PDF–9.2M

Select item 108129677.

Updates on Aβ Processing by Hsp90, BRICHOS, and Newly Reported Distinctive Chaperones

Mohammed Iqbal, Shea-Lorane Lewis, Shivani Padhye, Umesh Kumar Jinwal

Biomolecules. 2024 Jan; 14(1): 16. Published online 2023 Dec 22. doi: 10.3390/biom14010016

PMCID:: PMC10812967

Abstract Article PDF–1.3M

Select item 107649588.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 107466799.

Mutations F352A and Y528A in human HSP90α reduce fibronectin association and fibrillogenesis in cell-derived matrices.

Abir Chakraborty, Ronald Tonui, Adrienne Lesley Edkins

Cell Stress Chaperones. 2023 Nov; 28(6): 697–707. Published online 2023 Jun 23. doi: 10.1007/s12192-023-01362-9

PMCID:: PMC10746679

Abstract Article PDF–4.1M

Select item 1064152410.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 1062682711.

PER2 binding to HSP90 enhances immune response against oral squamous cell carcinoma by inhibiting IKK/NF-κB pathway and PD-L1 expression

Zhiwei Zhang, Deping Sun, Hong Tang, Jie Ren, Shilin Yin, Kai Yang

J Immunother Cancer. 2023; 11(11): e007627. Published online 2023 Nov 1. doi: 10.1136/jitc-2023-007627

PMCID:: PMC10626827

Abstract Article PDF–12M

Select item 1061767312.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 1056587613.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1056490814.

SIRT1 and HSP90α feed-forward circuit safeguards chromosome segregation integrity in diffuse large B cell lymphomas

Emilia Białopiotrowicz-Data, Monika Noyszewska-Kania, Ewa Jabłońska, Tomasz Sewastianik, Dorota Komar, Sonia Dębek, Filip Garbicz, Magdalena Wojtas, Maciej Szydłowski, Anna Polak, Patryk Górniak, Przemysław Juszczyński

Cell Death Dis. 2023 Oct; 14(10): 667. Published online 2023 Oct 11. doi: 10.1038/s41419-023-06186-0

PMCID:: PMC10564908

Abstract Article PDF–5.1M

Select item 1052950915.

Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery

Sarah J. Backe, Rebecca A. Sager, Jennifer A. Heritz, Laura A. Wengert, Katherine A. Meluni, Xavier Aran-Guiu, Barry Panaretou, Mark R. Woodford, Chrisostomos Prodromou, Dimitra Bourboulia, Mehdi Mollapour

Cell Rep. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112807. Published online 2023 Jul 14. doi: 10.1016/j.celrep.2023.112807

Correction in:: Cell Rep. 2024 Jan 23; 43(1): 113672.

PMCID:: PMC10529509

Abstract Article PDF–2.2M

Select item 1051408116.

HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma

Jinxin Zhang, Lixia Liu, Yan Li, Yaling Huang, Senbo Xiao, Zihao Deng, Zhenming Zheng, Jieyou Li, Manfeng Liang, Guantai Xie, Xiao Chen, Yaotang Deng, Wenchong Tan, Hairou Su, Guibing Wu, Chunqing Cai, Xuemei Chen, Fei Zou

Neoplasia. 2023 Oct; 44: 100935. Published online 2023 Sep 15. doi: 10.1016/j.neo.2023.100935

PMCID:: PMC10514081

Abstract Article PDF–14M

Select item 1048053517.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1046044818.

USP14 governs CYP2E1 to promote nonalcoholic fatty liver disease through deubiquitination and stabilization of HSP90AA1

Dongqin Wei, Xin Tian, Longbo Zhu, Han Wang, Chao Sun

Cell Death Dis. 2023 Aug; 14(8): 566. Published online 2023 Aug 26. doi: 10.1038/s41419-023-06091-6

PMCID:: PMC10460448

Abstract Article PDF–15M

Select item 1040007119.

Structural insight into guanylyl cyclase receptor hijacking of the kinase–Hsp90 regulatory mechanism

Nathanael A Caveney, Naotaka Tsutsumi, K Christopher Garcia

eLife. 2023; 12: RP86784. Published online 2023 Aug 3. doi: 10.7554/eLife.86784

PMCID:: PMC10400071

Abstract Article PDF–3.5M

Select item 1039839920.

HSP90AA1 promotes lymphatic metastasis of hypopharyngeal squamous cell carcinoma by regulating epithelial-mesenchymal transition

FENGXIANG TANG, YANSHI LI, MIN PAN, ZHIHAI WANG, TAO LU, CHUAN LIU, XIN ZHOU, GUOHUA HU

Oncol Res. 2023; 31(5): 787–803. Published online 2023 Jul 21. doi: 10.32604/or.2023.030081

PMCID:: PMC10398399

Abstract Article PDF–17M

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