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Select item 112415761.

Role of HDAC5 Epigenetics in Chronic Craniofacial Neuropathic Pain

Sifong Elise Hui, Karin N. Westlund

Int J Mol Sci. 2024 Jul; 25(13): 6889. Published online 2024 Jun 23. doi: 10.3390/ijms25136889

PMCID:: PMC11241576

Abstract Article PDF–750K

Select item 111481842.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 109408293.

Histone Trimethylations and HDAC5 Regulate Spheroid Subpopulation and Differentiation Signaling of Human Adipose-Derived Stem Cells

Ming-Min Chang, Yi-Kai Hong, Chao-Kai Hsu, Hans I-Chen Harn, Bu-Miin Huang, Ya-Hsin Liu, Fu-I Lu, Yuan-Yu Hsueh, Shau-Ping Lin, Chia-Ching Wu

Stem Cells Transl Med. 2024 Mar; 13(3): 293–308. Published online 2023 Dec 30. doi: 10.1093/stcltm/szad090

PMCID:: PMC10940829

Abstract Article PDF–55M

Select item 109332674.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 100348485.

Pharmacogenetic Analysis of Genes Implicated in Rodent Models of Antidepressant Response: Association of TREK1 and Treatment Resistance in the STAR*D Study

Roy H Perlis, Priya Moorjani, Jesen Fagerness, Shaun Purcell, Madhukar H Trivedi, Maurizio Fava, A John Rush, Jordan W Smoller

Neuropsychopharmacology. Author manuscript; available in PMC 2023 Mar 23.

Published in final edited form as: Neuropsychopharmacology. 2008 Nov; 33(12): 2810–2819. Published online 2008 Feb 20. doi: 10.1038/npp.2008.6

PMCID:: PMC10034848

Abstract Article PDF–667K

Select item 97559576.

HDAC5 Loss Enhances Phospholipid-Derived Arachidonic Acid Generation and Confers Sensitivity to cPLA2 Inhibition in Pancreatic Cancer

Penglin Pan, Gengdu Qin, Bo Wang, Haixin Yu, Jie Chen, Jiaying Liu, Kaijian Bing, Jian Shen, Dianyun Ren, Yuhan Zhao, Wentao Xia, Hui Li, Heshui Wu, Yingke Zhou

Cancer Res. 2022 Dec 16; 82(24): 4542–4554. Published online 2022 Sep 14. doi: 10.1158/0008-5472.CAN-21-4362

PMCID:: PMC9755957

Abstract Article PDF–16M

Select item 95765267.

HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation

Ya Gao, Yangdan Liu, Danning Zheng, Chiakang Ho, Dongsheng Wen, Jiaming Sun, Lu Huang, Yuxin Liu, Qingfeng Li, Yifan Zhang

Int J Biol Sci. 2022; 18(15): 5724–5739. Published online 2022 Sep 11. doi: 10.7150/ijbs.76140

PMCID:: PMC9576526

Abstract Article PDF–4.9M

Select item 95422758.

Epigenetic master regulators HDAC1 and HDAC5 control pathobiont Enterobacteria colonization in ileal mucosa of Crohn’s disease patients

Mélissa Chervy, Adeline Sivignon, Flavie Dambrine, Anthony Buisson, Pierre Sauvanet, Catherine Godfraind, Matthieu Allez, Lionel Le Bourhis, The Remind Group, Nicolas Barnich, Jérémy Denizot

Gut Microbes. 2022; 14(1): 2127444. Published online 2022 Sep 29. doi: 10.1080/19490976.2022.2127444

PMCID:: PMC9542275

Abstract Article PDF–7.5M

Select item 93576269.

HDAC5, negatively regulated by miR‐148a‐3p, promotes colon cancer cell migration

Chunli OuYang, Guang Shu, Jiaxin Liu, Shumin Deng, Pengyan Lu, Yimin Li, Yaqi Gan, Bintao Xie, Junwen Liu, Gang Yin

Cancer Sci. 2022 Aug; 113(8): 2560–2574. Published online 2022 Jun 5. doi: 10.1111/cas.15399

Correction in:: Cancer Sci. 2024 Apr; 115(4): 1361.

PMCID:: PMC9357626

Abstract Article PDF–14M

Select item 911973610.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 889958611.

HDAC5 modulates PD-L1 expression and cancer immunity via p65 deacetylation in pancreatic cancer

Yingke Zhou, Xin Jin, Haixin Yu, Gengdu Qin, Penglin Pan, Jingyuan Zhao, Taoyu Chen, Xueyi Liang, Yan Sun, Bo Wang, Dianyun Ren, Shikai Zhu, Heshui Wu

Theranostics. 2022; 12(5): 2080–2094. Published online 2022 Jan 31. doi: 10.7150/thno.69444

PMCID:: PMC8899586

Abstract Article PDF–3.3M

Select item 882889512.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 876907213.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 876331714.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 863404615.

Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-κB signaling

Chonghui Xu, Jielin Tang, Qi Yang, He Zhao, Yaling Liu, Juan Cao, Yuan Zhou, Xinwen Chen, Jizheng Chen

J Biol Chem. 2021 Dec; 297(6): 101380. Published online 2021 Nov 3. doi: 10.1016/j.jbc.2021.101380

PMCID:: PMC8634046

Abstract Article PDF–3.6M

Select item 855465216.

Impairment of human terminal erythroid differentiation by histone deacetylase 5 deficiency

Yaomei Wang, Wei Li, Vincent P. Schulz, Huizhi Zhao, Xiaoli Qu, Qian Qi, Yong Cheng, Xinhua Guo, Shijie Zhang, Xin Wei, Donghao Liu, Karina Yazdanbakhsh, Christopher D. Hillyer, Narla Mohandas, Lixiang Chen, Patrick G. Gallagher, Xiuli An

Blood. 2021 Oct 28; 138(17): 1615–1627. doi: 10.1182/blood.2020007401

Correction in:: Blood. 2022 Mar 10; 139(10): 1600.

PMCID:: PMC8554652

Abstract Article

Select item 843171717.

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation

Hongyi Zhou, Huabo Su, Weiqin Chen

Int J Mol Sci. 2021 Sep; 22(17): 9509. Published online 2021 Sep 1. doi: 10.3390/ijms22179509

PMCID:: PMC8431717

Abstract Article PDF–3.4M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 791794819.

Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer

Diamanto Skopelitou, Beiping Miao, Aayushi Srivastava, Abhishek Kumar, Magdalena Kuswick, Dagmara Dymerska, Nagarajan Paramasivam, Matthias Schlesner, Jan Lubinski, Kari Hemminki, Asta Försti, Obul Reddy Bandapalli

Int J Mol Sci. 2021 Feb; 22(4): 1837. Published online 2021 Feb 12. doi: 10.3390/ijms22041837

PMCID:: PMC7917948

Abstract Article PDF–1.3M

Select item 783863920.

Activation of Tripartite Motif Containing 63 Expression by Transcription Factor EB and Transcription Factor Binding to Immunoglobulin Heavy Chain Enhancer 3 Is Regulated by Protein Kinase D and Class IIa Histone Deacetylases

Cristina Pablo Tortola, Britta Fielitz, Yi Li, Julia Rüdebusch, Friedrich C. Luft, Jens Fielitz

Front Physiol. 2020; 11: 550506. Published online 2021 Jan 13. doi: 10.3389/fphys.2020.550506

PMCID:: PMC7838639

Abstract Article PDF–393K

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