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Select item 47916831.

Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State

Alessandra Folda, Anna Citta, Valeria Scalcon, Tito Calì, Francesco Zonta, Guido Scutari, Alberto Bindoli, Maria Pia Rigobello

Sci Rep. 2016; 6: 23071. Published online 2016 Mar 15. doi: 10.1038/srep23071

PMCID:: PMC4791683

Abstract Article PDF–1.5M

Select item 45924752.

SPG7 is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore

Santhanam Shanmughapriya, Sudarsan Rajan, Nicholas E. Hoffman, Andrew M. Higgins, Dhanendra Tomar, Neeharika Nemani, Kevin J. Hines, Dylan J. Smith, Akito Eguchi, Sandhya Vallem, Farah Shaikh, Maggie Cheung, Nicole J. Leonard, Ryan S. Stolakis, Matthew P. Wolfers, Jessica Ibetti, J. Kurt Chuprun, Neelakshi R. Jog, Steven R. Houser, Walter J. Koch, John W. Elrod, Muniswamy Madesh

Mol Cell. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Mol Cell. 2015 Oct 1; 60(1): 47–62. Published online 2015 Sep 17. doi: 10.1016/j.molcel.2015.08.009

PMCID:: PMC4592475

Abstract Article PDF–3.5M

Select item 37682713.

Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells

Raquel S. Carreira, Youngil Lee, Mariam Ghochani, Åsa B. Gustafsson, Roberta A. Gottlieb

Autophagy. Author manuscript; available in PMC 2013 Sep 10.

Published in final edited form as: Autophagy. 2010 May; 6(4): 462–472. Published online 2010 May 16. doi: 10.4161/auto.6.4.11553

PMCID:: PMC3768271

Abstract Article PDF–3.3M

Select item 33836244.

p53 opens the mitochondrial permeability transition pore to trigger necrosis

Angelina V. Vaseva, Natalia D. Marchenko, Kyungmin Ji, Stella E. Tsirka, Sonja Holzmann, Ute M. Moll

Cell. Author manuscript; available in PMC 2013 Jun 22.

Published in final edited form as: Cell. 2012 Jun 22; 149(7): 1536–1548. doi: 10.1016/j.cell.2012.05.014

PMCID:: PMC3383624

Abstract Article PDF–5.3M

Select item 32589055.

The Mitochondrial Phosphate Carrier Interacts with Cyclophilin D and May Play a Key Role in the Permeability Transition

Anna W. C. Leung, Pinadda Varanyuwatana, Andrew P. Halestrap

J Biol Chem. 2008 Sep 26; 283(39): 26312–26323. doi: 10.1074/jbc.M805235200

PMCID:: PMC3258905

Abstract Article PDF–751K

Select item 31780596.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 30626577.

Modulation of F₀F₁-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

Christos Chinopoulos, Csaba Konràd, Gergely Kiss, Eugeniy Metelkin, Beata Töröcsik, Steven F. Zhang, Anatoly A. Starkov

FEBS J. Author manuscript; available in PMC 2012 Apr 1.

Published in final edited form as: FEBS J. 2011 Apr; 278(7): 1112–1125. Published online 2011 Feb 23. doi: 10.1111/j.1742-4658.2011.08026.x

PMCID:: PMC3062657

Abstract Article PDF–774K

Select item 30143038.

Mitochondrion as a Novel Site of Dichloroacetate Biotransformation by Glutathione Transferase ζ1

Wenjun Li, Margaret O. James, Sarah C. McKenzie, Nigel A. Calcutt, Chen Liu, Peter W. Stacpoole

J Pharmacol Exp Ther. 2011 Jan; 336(1): 87–94. doi: 10.1124/jpet.110.173195

PMCID:: PMC3014303

Abstract Article PDF–721K

Select item 29573429.

Chronic ethanol consumption enhances sensitivity to Ca²⁺-mediated opening of the mitochondrial permeability transition pore and increases cyclophilin D in liver

Adrienne L. King, Telisha M. Swain, Dale A. Dickinson, Mathieu J. Lesort, Shannon M. Bailey

Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299(4): G954–G966. Published online 2010 Jul 22. doi: 10.1152/ajpgi.00246.2010

PMCID:: PMC2957342

Abstract Article

Select item 291122610.

Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases

Tara L. Davis, John R. Walker, Valérie Campagna-Slater, Patrick J. Finerty, Jr, Ragika Paramanathan, Galina Bernstein, Farrell MacKenzie, Wolfram Tempel, Hui Ouyang, Wen Hwa Lee, Elan Z. Eisenmesser, Sirano Dhe-Paganon

PLoS Biol. 2010 Jul; 8(7): e1000439. Published online 2010 Jul 27. doi: 10.1371/journal.pbio.1000439

PMCID:: PMC2911226

Abstract Article PDF–3.6M

Select item 286080711.

Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation

Sylvanie Malouitre, Henry Dube, David Selwood, Martin Crompton

Biochem J. 2010 Jan 1; 425(Pt 1): 137–148. Prepublished online 2009 Oct 15. Published online 2009 Dec 14. doi: 10.1042/BJ20090332

PMCID:: PMC2860807

Abstract Article PDF–892K

Select item 279716812.

Cyclophilin D Modulates Mitochondrial F₀F₁-ATP Synthase by Interacting with the Lateral Stalk of the Complex

Valentina Giorgio, Elena Bisetto, Maria Eugenia Soriano, Federica Dabbeni-Sala, Emy Basso, Valeria Petronilli, Michael A. Forte, Paolo Bernardi, Giovanna Lippe

J Biol Chem. 2009 Dec 4; 284(49): 33982–33988. Published online 2009 Sep 29. doi: 10.1074/jbc.M109.020115

PMCID:: PMC2797168

Abstract Article PDF–780K

Select item 277884413.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 266509014.

Cyclophilin D Interacts with Bcl2 and Exerts an Anti-apoptotic Effect

Roman A. Eliseev, Jonathan Malecki, Tobias Lester, Yu Zhang, John Humphrey, Thomas E. Gunter

J Biol Chem. 2009 Apr 10; 284(15): 9692–9699. doi: 10.1074/jbc.M808750200

PMCID:: PMC2665090

Abstract Article PDF–440K

Select item 265001215.

Cyclophilin D is predominantly expressed in mitochondria of GABAergic interneurons

Julie L. Hazelton, Maryna Petrasheuskaya, Gary Fiskum, Tibor Kristián

J Neurosci Res. Author manuscript; available in PMC 2010 Apr 1.

Published in final edited form as: J Neurosci Res. 2009 Apr; 87(5): 1250–1259. doi: 10.1002/jnr.21921

PMCID:: PMC2650012

Abstract Article PDF–2.5M

Select item 254655616.

Phosphate Is Essential for Inhibition of the Mitochondrial Permeability Transition Pore by Cyclosporin A and by Cyclophilin D Ablation

Emy Basso, Valeria Petronilli, Michael A. Forte, Paolo Bernardi

J Biol Chem. 2008 Sep 26; 283(39): 26307–26311. doi: 10.1074/jbc.C800132200

PMCID:: PMC2546556

Abstract Article PDF–338K

Select item 226703817.

Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels

Federica Chiara, Diego Castellaro, Oriano Marin, Valeria Petronilli, William S. Brusilow, Magdalena Juhaszova, Steven J. Sollott, Michael Forte, Paolo Bernardi, Andrea Rasola

PLoS One. 2008; 3(3): e1852. Published online 2008 Mar 19. doi: 10.1371/journal.pone.0001852

PMCID:: PMC2267038

Abstract Article PDF–973K

Select item 181779318.

Muscle denervation promotes opening of the permeability transition pore and increases the expression of cyclophilin D

Alexis Ascah, Jimmy Matas, Phillip F Gardiner, Eric Fontaine, Yan Burelle, Kristina Csukly

J Physiol. 2006 Jul 1; 574(Pt 1): 319–327. Published online 2006 May 4. doi: 10.1113/jphysiol.2006.109702

PMCID:: PMC1817793

Abstract Article PDF–406K

Select item 121986919.

Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition.

K Woodfield, A Rück, D Brdiczka, A P Halestrap

Biochem J. 1998 Dec 1; 336(Pt 2): 287–290. doi: 10.1042/bj3360287

PMCID:: PMC1219869

Summary PDF–153K

Select item 118933320.

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

Anna C. Schinzel, Osamu Takeuchi, Zhihong Huang, Jill K. Fisher, Zhipeng Zhou, Jeffery Rubens, Claudio Hetz, Nika N. Danial, Michael A. Moskowitz, Stanley J. Korsmeyer

Proc Natl Acad Sci U S A. 2005 Aug 23; 102(34): 12005–12010. Published online 2005 Aug 15. doi: 10.1073/pnas.0505294102

PMCID:: PMC1189333

Abstract Article PDF–552K

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