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Select item 112099351.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 110308362.

Structure and function of ETAA16: a novel cell surface antigen in Ewing’s tumours

A. Borowski, U. Dirksen, L. Lixin, R. L. Shi, U. Göbel, E. M. Schneider

Cancer Immunol Immunother. 2006 Apr; 55(4): 363–374. Published online 2005 Jul 8. doi: 10.1007/s00262-005-0017-6

PMCID:: PMC11030836

Abstract Article PDF–752K

Select item 102297433.

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN

Kaini Zhang, Chen Yang, Xin Zhou, Jin Liang, Jianjin Guo, Min Li, Yi Zhang, Shulin Shao, Peng Sun, Kai Li, Jingjing Huang, Fang Chen, Xiubin Liang, Dongming Su

Cell Mol Life Sci. 2023 Jun; 80(6): 168. Published online 2023 May 30. doi: 10.1007/s00018-023-04820-w

PMCID:: PMC10229743

Abstract Article PDF–2.9M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 82577125.

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates

David Schlütermann, Niklas Berleth, Jana Deitersen, Nora Wallot-Hieke, Olena Friesen, Wenxian Wu, Fabian Stuhldreier, Yadong Sun, Lena Berning, Annabelle Friedrich, María José Mendiburo, Christoph Peter, Constanze Wiek, Helmut Hanenberg, Anja Stefanski, Kai Stühler, Björn Stork

Sci Rep. 2021; 11: 13863. Published online 2021 Jul 5. doi: 10.1038/s41598-021-92408-4

PMCID:: PMC8257712

Abstract Article PDF–3.2M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81080937.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 79947908.

ATR activation is regulated by dimerization of ATR activating proteins

Vaughn Thada, David Cortez

J Biol Chem. 2021 Jan-Jun; 296: 100455. Published online 2021 Feb 24. doi: 10.1016/j.jbc.2021.100455

PMCID:: PMC7994790

Abstract Article PDF–2.1M

Select item 72900329.

MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage

Jen-Wei Huang, Ananya Acharya, Angelo Taglialatela, Tarun S. Nambiar, Raquel Cuella-Martin, Giuseppe Leuzzi, Samuel B. Hayward, Sarah A. Joseph, Gregory J. Brunette, Roopesh Anand, Rajesh K. Soni, Nathan L. Clark, Kara A. Bernstein, Petr Cejka, Alberto Ciccia

Nat Commun. 2020; 11: 2948. Published online 2020 Jun 11. doi: 10.1038/s41467-020-16718-3

PMCID:: PMC7290032

Abstract Article PDF–3.0M

Select item 689109710.

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

Divya Achuthankutty, Roshan Singh Thakur, Peter Haahr, Saskia Hoffmann, Alexandros P. Drainas, Anna H. Bizard, Joachim Weischenfeldt, Ian D. Hickson, Niels Mailand

J Cell Biol. 2019 Dec 2; 218(12): 3943–3953. Published online 2019 Oct 15. doi: 10.1083/jcb.201905064

PMCID:: PMC6891097

Abstract Article PDF–2.7M

Select item 654486411.

Common motifs in ETAA1 and TOPBP1 required for ATR kinase activation

Vaughn Thada, David Cortez

J Biol Chem. 2019 May 24; 294(21): 8395–8402. Published online 2019 Apr 2. doi: 10.1074/jbc.RA119.008154

PMCID:: PMC6544864

Abstract Article PDF–2.0M

Select item 644685712.

Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1

Thomas E. Bass, David Cortez

J Cell Biol. 2019 Apr 1; 218(4): 1235–1249. Published online 2019 Feb 12. doi: 10.1083/jcb.201810058

PMCID:: PMC6446857

Abstract Article PDF–4.3M

Select item 636530513.

An intrinsic S/G2 checkpoint enforced by ATR

Joshua C. Saldivar, Stephan Hamperl, Michael J. Bocek, Mingyu Chung, Thomas E. Bass, Fernanda Cisneros-Soberanis, Kumiko Samejima, Linfeng Xie, James R. Paulson, William C. Earnshaw, David Cortez, Tobias Meyer, Karlene A. Cimprich

Science. Author manuscript; available in PMC 2019 Feb 24.

Published in final edited form as: Science. 2018 Aug 24; 361(6404): 806–810. doi: 10.1126/science.aap9346

PMCID:: PMC6365305

Abstract Article PDF–1.0M

Select item 524586114.

ETAA1 acts at stalled replication forks to maintain genome integrity

Thomas E. Bass, Jessica W. Luzwick, Gina Kavanaugh, Clinton Carroll, Huzefa Dungrawala, Gloria G. Glick, Michael D. Feldkamp, Reid Putney, Walter J. Chazin, David Cortez

Nat Cell Biol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Nat Cell Biol. 2016 Nov; 18(11): 1185–1195. Published online 2016 Oct 10. doi: 10.1038/ncb3415

PMCID:: PMC5245861

Abstract Article PDF–2.8M

Select item 517339615.

RPA-binding protein ETAA1 is an ATR activator involved in DNA replication stress response

Yuan-Cho Lee, Qing Zhou, Junjie Chen, Jingsong Yuan

Curr Biol. Author manuscript; available in PMC 2017 Dec 19.

Published in final edited form as: Curr Biol. 2016 Dec 19; 26(24): 3257–3268. Published online 2016 Nov 3. doi: 10.1016/j.cub.2016.10.030

PMCID:: PMC5173396

Abstract Article PDF–2.2M

Select item 506397916.

Ewing Tumor-associated Antigen 1 Interacts with Replication Protein A to Promote Restart of Stalled Replication Forks

Sumin Feng, Yichao Zhao, Yixi Xu, Shaokai Ning, Wei Huo, Mei Hou, Ge Gao, Jianguo Ji, Rong Guo, Dongyi Xu

J Biol Chem. 2016 Oct 14; 291(42): 21956–21962. Published online 2016 Sep 6. doi: 10.1074/jbc.C116.747758

PMCID:: PMC5063979

Abstract Article PDF–1.7M

Select item 480585517.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Abstract Article PDF–4.6M

Select item 432443918.

Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2

Jeffrey T. Galligan, Gustavo Martinez-Noël, Verena Arndt, Sebastian Hayes, Thomas W. Chittenden, J. Wade Harper, Peter M. Howley

J Proteome Res. 2015 Feb 6; 14(2): 953–966. Published online 2014 Dec 4. doi: 10.1021/pr501005v

PMCID:: PMC4324439

Abstract Article PDF–7.5M

Select item 374444319.

Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci

Ching-Ti Liu, Keri L. Monda, Kira C. Taylor, Leslie Lange, Ellen W. Demerath, Walter Palmas, Mary K. Wojczynski, Jaclyn C. Ellis, Mara Z. Vitolins, Simin Liu, George J. Papanicolaou, Marguerite R. Irvin, Luting Xue, Paula J. Griffin, Michael A. Nalls, Adebowale Adeyemo, Jiankang Liu, Guo Li, Edward A. Ruiz-Narvaez, Wei-Min Chen, Fang Chen, Brian E. Henderson, Robert C. Millikan, Christine B. Ambrosone, Sara S. Strom, Xiuqing Guo, Jeanette S. Andrews, Yan V. Sun, Thomas H. Mosley, Lisa R. Yanek, Daniel Shriner, Talin Haritunians, Jerome I. Rotter, Elizabeth K. Speliotes, Megan Smith, Lynn Rosenberg, Josyf Mychaleckyj, Uma Nayak, Ida Spruill, W. Timothy Garvey, Curtis Pettaway, Sarah Nyante, Elisa V. Bandera, Angela F. Britton, Alan B. Zonderman, Laura J. Rasmussen-Torvik, Yii-Der Ida Chen, Jingzhong Ding, Kurt Lohman, Stephen B. Kritchevsky, Wei Zhao, Patricia A. Peyser, Sharon L. R. Kardia, Edmond Kabagambe, Ulrich Broeckel, Guanjie Chen, Jie Zhou, Sylvia Wassertheil-Smoller, Marian L. Neuhouser, Evadnie Rampersaud, Bruce Psaty, Charles Kooperberg, JoAnn E. Manson, Lewis H. Kuller, Heather M. Ochs-Balcom, Karen C. Johnson, Lara Sucheston, Jose M. Ordovas, Julie R. Palmer, Christopher A. Haiman, Barbara McKnight, Barbara V. Howard, Diane M. Becker, Lawrence F. Bielak, Yongmei Liu, Matthew A. Allison, Struan F. A. Grant, Gregory L. Burke, Sanjay R. Patel, Pamela J. Schreiner, Ingrid B. Borecki, Michele K. Evans, Herman Taylor, Michele M. Sale, Virginia Howard, Christopher S. Carlson, Charles N. Rotimi, Mary Cushman, Tamara B. Harris, Alexander P. Reiner, L. Adrienne Cupples, Kari E. North, Caroline S. Fox

PLoS Genet. 2013 Aug; 9(8): e1003681. Published online 2013 Aug 15. doi: 10.1371/journal.pgen.1003681

PMCID:: PMC3744443

Abstract Article PDF–2.2M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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